The Influence of an Adsorbate Layer on Adatom Diffusion and Island Nucleation: Fe on Si(111)-√3 x √3-Au

Using scanning tunneling microscopy, the influence of a thin Au layer on the diffusion of Fe adatoms and the subsequent island nucleation on a Si(111) surface is investigated. The adsorbate induces thestructure that increases the surface mobility of subsequently deposited Fe atoms, resulting in the formation well-defined nanoclusters. Surprisingly, the domain walls—inherent to the reconstruction—do not influence the surface diffusion, which demonstrates that the passivation is of much more importance for the self-assembly than the surface corrugation. Using the decoupling of the diffusion and nucleationonthe surface and the reactionwiththe surface and conventional nucleation theory, the activation energy for surface diffusionEd = 0.61 eV and the critical cluster sizei = 3 are determined, which reveal the microscopic details of the diffusion and nucleation processes

Electrochemical detection of Toxocara canis excretory-secretory antigens in children from rural communities in Esmeraldas Province, Ecuador: association between active infection and high eosinophilia.

BACKGROUND: The diagnosis of active Toxocara canis infections in humans is challenging. Larval stages of T. canis do not replicate in human tissues and disease may result from infection with a single T. canis larva. Recently, we developed a nanobody-based electrochemical magnetosensor assay with superior sensitivity to detect T. canis excretory-secretory (TES) antigens. Here, we evaluate the performance of the assay in children from an Ecuadorian birth cohort that followed children to five years of age. METHODS: Samples were selected based on the presence of peripheral blood eosinophilia and relative eosinophil counts. The samples were analyzed by the nanobody-based electrochemical magnetosensor assay, which utilizes a bivalent biotinylated nanobody as capturing agent on the surface of streptavidin pre-coated paramagnetic beads. Detection was performed by a different nanobody chemically labelled with horseradish peroxidase. RESULTS: Of 87 samples tested, 33 (38%) scored positive for TES antigen recognition by the electrochemical magnetosensor assay. The average concentration of TES antigen in serum was 2.1 ng/ml (SD = 1.1). The positive result in the electrochemical assay was associated with eosinophilia > 19% (P = 0.001). Parasitological data were available for 57 samples. There was no significant association between positivity by the electrochemical assay and the presence of other soil-transmitted helminth infections. CONCLUSIONS: Our nanobody-based electrochemical assay provides highly sensitive quantification of TES antigens in serum and has potential as a valuable tool for the diagnosis of active human toxocariasis

Understanding the effect of confinement in scanning spreading resistance microscopy measurements

Scanning spreading resistance microscopy (SSRM) is a powerful technique for quantitative two-and three-dimensional carrier profiling of semiconductor devices with sub-nm spatial resolution. However, considering the sub-10 nm dimensions of advanced devices and the introduction of three-dimensional architectures like fin field effect transistor (FinFET) and nanowires, the measured spreading resistance is easily impacted by parasitic series resistances present in the system. The limited amount of material, the presence of multiple interfaces, and confined current paths may increase the total resistance measured by SSRM beyond the expected spreading resistance, which can ultimately lead to an inaccurate carrier quantification. Here, we report a simulation assisted experimental study to identify the different parameters affecting the SSRM measurements in confined volumes. Experimentally, the two-dimensional current confinement is obtained by progressively thinning down uniformly doped blanket silicon on insulator wafers using scalpel SSRM. The concomitant SSRM provides detailed electrical information as a function of depth up to oxide interface. We show that the resistance is most affected by the interface traps in case of a heterogeneous sample, followed by the intrinsic resistance of the current carrying paths. Furthermore, we show that accurate carrier quantification is ensured for typical back contact distances of 1 μm if the region of interest is at least nine times larger than the probe radius. © 2020 Author(s)

Millibots: The Development of a Framework and Algorithms for a Distributed Heterogeneous Robot Team

The definitive article was published in IEEE Robotics and Automation Magazine, Volume 9, Issue 4, located at http://ieeexplore.ieee.org/ (DOI: 10.1109/MRA.2002.1160069) © Institute of Electrical and Electronics Engineers (IEEE)

RAVE: A Real and Virtual Environment for Multiple Mobile Robot Systems

This paper was presented at the 1999 IEEE/RSJ International Conference on Intelligent Robots and Systems (IROS'99), Kyongju, Korea, October 17-21. The definitive paper is located at http://ieeexplore.ieee.org (DOI: 10.1109/IROS.1999.811669). © IEEE.To focus on the research issues surrounding collaborative behavior in multiple mobile-robotic systems, a great amount of low-level infrastructure is required. To facilitate our on-going research into multi-robot systems, we have developed RAVE, a software framework that provides a Real And Virtual Environment for running and managing multiple heterogeneous mobile-robot systems. This framework simplifies the implementation and development of collaborative robotic systems by providing the following capabilities: the ability to run systems off-line in simulation, user-interfaces for observing and commanding simulated and real robots, transparent transference of simulated robot programs to real robots, the ability to have simulated robots interact with real robots, and the ability to place virtual sensors on real robots to augment or experiment with their performance

Heterogeneous Teams of Modular Robots for Mapping and Exploration

The definitive article is published in Autonomous Robots. It is available at http://www.springerlink.com (DOI: DOI: 10.1023/A:1008933826411). © Springer-VerlagIn this article, we present the design of a team of heterogeneous, centimeter-scale robots that collaborate to map and explore unknown environments. The robots, called Millibots, are configured from modular components that include sonar and IR sensors, camera, communication, computation, and mobility modules. Robots with different configurations use their special capabilities collaboratively to accomplish a given task. For mapping and exploration with multiple robots, it is critical to know the relative positions of each robot with respect to the others. We have developed a novel localization system that uses sonar-based distance measurements to determine the positions of all the robots in the group. With their positions known, we use an occupancy grid Bayesian mapping algorithm to combine the sensor data from multiple robots with different sensing modalities. Finally, we present the results of several mapping experiments conducted by a user-guided team of five robots operating in a room containing multiple obstacles

Thermodynamic properties of Pt nanoparticles: Size, shape, support, and adsorbate effects

This study presents a systematic investigation of the thermodynamic properties of free and γ-Al2O3-supported size-controlled Pt nanoparticles (NPs) and their evolution with decreasing NP size. A combination of in situ extended x-ray absorption fine-structure spectroscopy (EXAFS), ex situ transmission electron microscopy (TEM) measurements, and NP shape modeling revealed (i) a cross over from positive to negative thermal expansion with decreasing particle size, (ii) size- and shape-dependent changes in the mean square bond-projected bond-length fluctuations, and (iii) enhanced Debye temperatures (ΘD, relative to bulk Pt) with a bimodal size-dependence for NPs in the size range of ∼0.8–5.4 nm. For large NP sizes (diameter d >1.5 nm) ΘD was found to decrease toward ΘD of bulk Pt with increasing NP size. For NPs ≤ 1 nm, a monotonic decrease of ΘD was observed with decreasing NP size and increasing number of low-coordinated surface atoms. Our density functional theory calculations confirm the size- and shape-dependence of the vibrational properties of our smallest NPs and show how their behavior may be tuned by H desorption from the NPs. The experimental results can be partly attributed to thermally induced changes in the coverage of the adsorbate (H2) used during the EXAFS measurements, bearing in mind that the interaction of the Pt NPs with the stiff, high-melting temperature γ-Al2O3 support may also play a role. The calculations also provide good qualitative agreement with the trends in the mean square bond-projected bond-length fluctuations measured via EXAFS. Furthermore, they revealed that part of the ΘD enhancement observed experimentally for the smallest NPs (d ≤ 1 nm) might be assigned to the specific sensitivity of EXAFS, which is intrinsically limited to bond-projected bond-length fluctuations

Thermodynamic properties of Pt nanoparticles: Size, shape, support, and adsorbate effects

This study presents a systematic investigation of the thermodynamic properties of free and gamma-Al2O3-supported size-controlled Pt nanoparticles (NPs) and their evolution with decreasing NP size. A combination of in situ extended x-ray absorption fine-structure spectroscopy (EXAFS), ex situ transmission electron microscopy (TEM) measurements, and NP shape modeling revealed (i) a cross over from positive to negative thermal expansion with decreasing particle size, (ii) size- and shape-dependent changes in the mean square bond-projected bond-length fluctuations, and (iii) enhanced Debye temperatures (D-circle minus, relative to bulk Pt) with a bimodal size- dependence for NPs in the size range of similar to 0.8-5.4 nm. For large NP sizes (diameter d \u3e 1.5 nm) D-circle minus was found to decrease toward D-circle minus of bulk Pt with increasing NP size. For NPs \u3c = 1 nm, a monotonic decrease of D-circle minus was observed with decreasing NP size and increasing number of low-coordinated surface atoms. Our density functional theory calculations confirm the size- and shape-dependence of the vibrational properties of our smallest NPs and show how their behavior may be tuned by H desorption from the NPs. The experimental results can be partly attributed to thermally induced changes in the coverage of the adsorbate (H-2) used during the EXAFS measurements, bearing in mind that the interaction of the Pt NPs with the stiff, high-melting temperature gamma-Al2O3 support may also play a role. The calculations also provide good qualitative agreement with the trends in the mean square bond-projected bond-length fluctuations measured via EXAFS. Furthermore, they revealed that part of the D-circle minus enhancement observed experimentally for the smallest NPs (d \u3c = 1 nm) might be assigned to the specific sensitivity of EXAFS, which is intrinsically limited to bond-projected bond-length fluctuations

Intramolecular locking and coumarin insertion: a stepwise approach for TADF design

Three novel TADF (thermally activated delayed fluorescence) emitters based on the well-studied Qx-Ph-DMAC fluorophore are designed and synthesized. The photophysical properties of these materials are studied from a theoretical and experimental point of view, demonstrating the cumulative effects of multiple small modifications that combine to afford significantly improved TADF performance. First, an extra phenyl ring is added to the acceptor part of Qx-Ph-DMAC to increase the conjugation length, resulting in BQx-Ph-DMAC, which acts as an intermediate molecular structure. Next, an electron-deficient coumarin unit is incorporated to fortify the electron accepting ability, affording ChromPy-Ph-DMAC with red-shifted emission. Finally, the conjugated system is further enlarged by ‘locking’ the molecular structure, generating DBChromQx-DMAC with further red-shifted emission. The addition of the coumarin unit significantly impacts the charge-transfer excited state energy levels with little effect on the locally excited states, resulting in a decrease of the singlet–triplet energy gap. As a result, the two coumarin-based emitters show considerably improved TADF performance in 1 w/w% zeonex films when compared to the initial Qx-Ph-DMAC structure. ‘Locking’ the molecular structure further lowers the singlet–triplet energy gap, resulting in more efficient reverse intersystem crossing and increasing the contribution of TADF to the total emission

DETC2002/CIE-xx SUPPORTING DESIGN REFINEMENT IN MEMS DESIGN

ABSTRACT We present a framework to support design refinement during the virtual prototyping of microelectromechanical systems (MEMS). By instantiating MEMS components and connecting them to each other via ports, the designer can both configure complex systems and simulate them. We examine design refinement in the context of ease of use and representation of the virtual prototype. We propose the use of a common, formal grammar representation for the design entities in the virtual prototypeMEMS components, behavioral models and CAD models. We show that the formal grammar approach leads to easy creation of virtual prototypes. In this paper, we focus on portsthe fundamental building blocks of a virtual prototype. Ports mediate all interactions within and between aspects of the virtual prototype. For even moderately complex designs, there can be many interactions present. The representation and organization of all possible ports is important in the context of design refinement. We provide a set-theoretic formalism that defines the algebra of ports. We present a formal grammar for ports that represents a port as a set of attributes, and provide a design refinement mechanism that involves adding or modifying attributes in the port. We illustrate our framework with a MEMS example. We demonstrate that the MEMS designer can evaluate multiple design alternatives quickly and accurately with our framework. KEYWORDS Design methodology, MEMS, Simulation-based design, attribute grammars, port-based modeling, Modelica INTRODUCTION AND MOTIVATION Virtual prototyping can shorten the design cycle of MEMS products by reducing the need for expensive and timeconsuming physical prototyping. The designer can evaluate more design alternatives to obtain a better quality design. In this paper, we propose to support the process of virtual prototyping of multi-disciplinary MEMS systems. We focus our attention on those aspects of virtual prototyping that are particularly important in the context of design refinement. Specifically, we further the current state-of-the-art with respect to representation and ease of use. The system-level design process is usually top-down. The designer begins with a high-level functional description that he decomposes into sub-functions. These sub-functions are assigned to a system architecture as a configuration of components that contain both design specifications and simulation models. When further decomposition or component assignment is not desired, the designer composes the components to create a system-level configuration that is evaluated to verify the function. In this process, there are three recurring themes: composition, or combining subcomponents to create a compound component; reuse, or replacing a componen