530 research outputs found

    Social, environmental and economic impacts of alternative energy and fuel supply chains

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    Energy supply nowadays, being a vital element of a country’s development, has to independently meet diverse, sustainability criteria, be it economic, environmental and social. The main goal of the present research work is to present a methodological framework for the evaluation of alternative energy and fuel Supply Chains (SCs), consisting of a broad topology (representation) suggested, encompassing all the well-known energy and fuel SCs, under a unified scheme, a set of performance measures and indices as well as mathematical model development, formulated as Multi-objective Linear Programming with the extension of incorporating binary decisions as well (Multi-objective Mixed Integer-Linear programming). Basic characteristics of the current modelling approach include the adaptability of the model to be applied at different levels of energy SCs decisions, under different time frames and for multiple stakeholders. Model evaluation is carried for a set of Greek islands, located in the Aegean Archipelagos, examining both the existing energy supply options as well future, more sustainable Energy Supply Chains (ESCs) configurations. Results of the specific research work reveal the social and environmental costs which are underestimated under the traditional energy supply options' evaluation, as well as the benefits that may be produced from renewable energy based applications in terms of social security and employment

    THE ROLE OF LEADERSHIP IN CORRUPTION AND MISCONDUCT SCANDALS IN THE U.S. MILITARY

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    Includes Supplementary MaterialThis study explores the role of leadership in three high-profile corruption and misconduct scandals—the Fat Leonard scandal, the murder of SPC Vanessa Guillén, and the Abu Ghraib Prison scandal—that occurred in the U.S. military over several decades. Additionally, the research delves into the culture of corrupt military commands and investigates patterns of leadership behavior that set the conditions for wrongdoing to occur. This way, the research goes beyond the often-cited “one bad apple” explanation examining organizational wrongdoing as a process. Using a qualitative research approach and utilizing an existing theoretical model, I categorize and evaluate publicly available data. The research findings illustrate that leaders’ actions or inaction directly triggered corruption or misconduct in two out of three scandals; however, leadership was indirectly involved in the third case study. Organizational culture also had a normalizing effect attracting more severe transgression. Lastly, leaders were found mindful of misbehavior in all cases, tacitly or overtly authorized misconduct, and failed to cultivate an ethical organizational culture. These results show that systemic deficiencies and leadership failures continue afflicting DOD and articulate the need for more drastic policies. Based on the findings, recommendations for the DOD are provided and explained.Outstanding ThesisLohagos, Hellenic ArmyApproved for public release. Distribution is unlimited

    The Applicability of RFID for Indoor Localization

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    Chapter 11 : The applicability of RFID for indoor localizatio

    A Simple and Fast Method for the Formation and Downstream Processing of Cancer-Cell-Derived 3D Spheroids: An Example Using Nicotine-Treated A549 Lung Cancer 3D Spheres.

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    Although 2D in vitro cancer cell cultures have been used for decades as a first line-of-research tool to investigate antitumoral drugs and treatments, their use presents many drawbacks, including the poor resemblance of such cultures to the characteristics of in vivo tumors. To mitigate these drawbacks, 3D culture models have emerged as a more representative alternative. Cancer cells cultured as 3D structures have the advantage of resembling solid tumors in their architecture and in their resistance to chemotherapeutic drugs, in part because of restrained drug penetration. Additionally, these 3D structures create a more physiological environment for the study of immune cell invasion and migration, comparable to solid tumors. In this paper, we describe a fast and cost-effective step-by-step protocol for the generation of 3D spheres using ultra-low-attachment (ULA) multiwell plates, which can be incorporated into the normal workflow of any laboratory. Using this protocol, spheroids of different human cancer cell lines can be obtained and can then be characterized on the basis of their morphology, viability, and expression of specific markers
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