Team Electronic Gameplay Combining Different Means of Control

Disclosed are methods and apparatuses provided for modifying the effect of an operator controlled input device on an interactive device to encourage the self-regulation of at least one physiological activity by a person different than the operator. The interactive device comprises a display area which depicts images and apparatus for receiving at least one input from the operator controlled input device to thus permit the operator to control and interact with at least some of the depicted images. One effect modification comprises measurement of the physiological activity of a person different from the operator, while modifying the ability of the operator to control and interact with at least some of the depicted images by modifying the input from the operator controlled input device in response to changes in the measured physiological signal

Effects of abiotic stressors on lutein production in the green microalga Dunaliella salina.

BackgroundRecent years have witnessed a rising trend in exploring microalgae for valuable carotenoid products as the demand for lutein and many other carotenoids in global markets has increased significantly. In green microalgae lutein is a major carotenoid protecting cellular components from damage incurred by reactive oxygen species under stress conditions. In this study, we investigated the effects of abiotic stressors on lutein accumulation in a strain of the marine microalga D. salina which had been selected for growth under stress conditions of combined blue and red lights by adaptive laboratory evolution.ResultsNitrate concentration, salinity and light quality were selected as three representative influencing factors and their impact on lutein production in batch cultures of D. salina was evaluated using response surface analysis. D. salina was found to be more tolerant to hyper-osmotic stress than to hypo-osmotic stress which caused serious cell damage and death in a high proportion of cells while hyper-osmotic stress increased the average cell size of D. salina only slightly. Two models were developed to explain how lutein productivity depends on the stress factors and for predicting the optimal conditions for lutein productivity. Among the three stress variables for lutein production, stronger interactions were found between nitrate concentration and salinity than between light quality and the other two. The predicted optimal conditions for lutein production were close to the original conditions used for adaptive evolution of D. salina. This suggests that the conditions imposed during adaptive evolution may have selected for the growth optima arrived at.ConclusionsThis study shows that systematic evaluation of the relationship between abiotic environmental stresses and lutein biosynthesis can help to decipher the key parameters in obtaining high levels of lutein productivity in D. salina. This study may benefit future stress-driven adaptive laboratory evolution experiments and a strategy of applying stress in a step-wise manner can be suggested for a rational design of experiments

Iron status in 6-y-old children: associations with growth and earlier iron status

To access publisher full text version of this article. Please click on the hyperlink in Additional Links fieldOBJECTIVE: To investigate the iron status of 6-y-old children and its association with growth and earlier iron status. DESIGN: In a cross-sectional study, children's body size measurements were recorded and blood samples taken near their sixth birthday. SUBJECTS: A sample of 188 children, randomly selected in two previous studies, was contacted, and 139(74%) agreed to participate. RESULTS: No children had iron deficiency anaemia, one was iron-deficient (serum ferritin (SF) or =15 microg/l (258+/-31%; n=49) (P=0.001). MCV at 2 y predicted weight gain from 2 to 6 y (B+/-s.e.=1.721+/-0.581; P=0.005; adj. R2=0.153) (n=44); also, children with SF or =15 microg/l (n=35) gained 9.6+/-2.8 kg (P=0.007), furthermore a difference was seen in proportional weight gain from 2 to 6 y between children with depleted iron stores at 2 y and not, or 156+/-13 vs 169+/-18% (P=0.038). CONCLUSION: The results suggest that low iron status at 1 and 2 y might lead to slower growth up to 6 y of age. Low iron status at 1 and 2 y and/or slower growth from 1 and 2 y up to 6 y might contribute to worse iron status at 6 y, while faster growth in early childhood is related to lower iron status

Experimental test of universal complementarity relations

Complementarity restricts the accuracy with which incompatible quantum observables can be jointly measured. Despite popular conception, the Heisenberg uncertainty relation does not quantify this principle. We report the experimental verification of universally valid complementarity relations, including an improved relation derived here. We exploit Einstein-Poldolsky-Rosen correlations between two photonic qubits, to jointly measure incompatible observables of one. The product of our measurement inaccuracies is low enough to violate the widely used, but not universally valid, Arthurs-Kelly relation.Comment: 8 pages, 4 figure

Using weak values to experimentally determine "negative probabilities" in a two-photon state with Bell correlations

Bipartite quantum entangled systems can exhibit measurement correlations that violate Bell inequalities, revealing the profoundly counter-intuitive nature of the physical universe. These correlations reflect the impossibility of constructing a joint probability distribution for all values of all the different properties observed in Bell inequality tests. Physically, the impossibility of measuring such a distribution experimentally, as a set of relative frequencies, is due to the quantum back-action of projective measurements. Weakly coupling to a quantum probe, however, produces minimal back-action, and so enables a weak measurement of the projector of one observable, followed by a projective measurement of a non-commuting observable. By this technique it is possible to empirically measure weak-valued probabilities for all of the values of the observables relevant to a Bell test. The marginals of this joint distribution, which we experimentally determine, reproduces all of the observable quantum statistics including a violation of the Bell inequality, which we independently measure. This is possible because our distribution, like the weak values for projectors on which it is built, is not constrained to the interval [0, 1]. It was first pointed out by Feynman that, for explaining singlet-state correlations within "a [local] hidden variable view of nature ... everything works fine if we permit negative probabilities". However, there are infinitely many such theories. Our method, involving "weak-valued probabilities", singles out a unique set of probabilities, and moreover does so empirically.Comment: 9 pages, 3 figure