9 research outputs found
Preferential uptake of polyunsaturated fatty acids by colorectal cancer cells
Although a growing body of evidence suggests that colorectal cancer (CRC) is associated with alterations of fatty acid (FA) profiles in serum and tumor tissues, available data about polyunsaturated fatty acid (PUFA) content in CRC patients are inconclusive. Our study showed that CRC tissues contained more PUFAs than normal large intestinal mucosa. However, serum levels of PUFAs in CRC patients were lower than in healthy controls. To explain the mechanism of PUFA alterations in CRC, we measured FA uptake by the colon cancer cells and normal colon cells. The levels of PUFAs in colon cancer cell culture medium decreased significantly with incubation time, while no changes were observed in the medium in which normal colon cells were incubated. Our findings suggest that the alterations in tumor and serum PUFA profiles result from preferential uptake of these FAs by cancer cells; indeed, PUFAs are essential for formation of cell membrane phospholipids during rapid proliferation of cancer cells. This observation puts into question potential benefits of PUFA supplementation in CRC patients
Chemical Additives for Corrosion Control in Desalination Plants
The addition of chemical additives has been considered as a standard
operation in water treatment systems. This chapter discusses the chemical
additives used for the control of corrosion in desalination systems. Specifically,
corrosion inhibitors for various metallurgies, biocides, and oxygen scavengers
are covered. The pros and cons of the additive chemicals have been
highlighted. The need to utilize green corrosion inhibitors based on plants and
ionic liquids materials have been emphasized. This class of materials are
environmentally friendly, cheap, and readily available