136 research outputs found
Entwicklung von Bekämpfungsstrategien für Meloidogyne halpa und Pratylenchus spp. im ökologischen Anbau von Möhren und Zwiebeln
Nematoden der Gattungen Meloidogyne und Pratylenchus zählen zu den Hauptschaderregern im ökologischen Anbau von Möhren und Zwiebeln. Typische Symptome sind geringes Wachstum, Deformationen der Ernteorgane, verstärkte Seitenwurzelbildung sowie Wurzelgallen (Meloidogyne) bzw. Wurzelläsionen (Pratylenchus). Beide Nematodengattungen haben ein sehr weites Wirtspflanzenspektrum und treten häufig gemeinsam auf. In dem vorliegenden Forschungsvorhaben werden Bekämpfungsstrategien für Meloidogyne und Pratylenchus unter praxisüblichen Bedingungen entwickelt
dE/dx electronics for MARK II experiment at SLAC
This paper describes a 100 MHz pulse digitizer for dE/dx measurements on the MARK II drift chamber at SLAC. The electronics provides the read-out of the detector's 5832 sense based on a 16-channel FASTBUS module. The basic element of the module is the TRW 6-bit Flash-ADC
Papillary Renal Cell Carcinomas Rewire Glutathione Metabolism and Are Deficient in Both Anabolic Glucose Synthesis and Oxidative Phosphorylation
Papillary renal cell carcinoma (pRCC) is a malignant kidney cancer with a prevalence of 7–20% of all renal tumors. Proteome and metabolome profiles of 19 pRCC and patient-matched healthy kidney controls were used to elucidate the regulation of metabolic pathways and the underlying molecular mechanisms. Glutathione (GSH), a main reactive oxygen species (ROS) scavenger, was highly increased and can be regarded as a new hallmark in this malignancy. Isotope tracing of pRCC derived cell lines revealed an increased de novo synthesis rate of GSH, based on glutamine consumption. Furthermore, profound downregulation of gluconeogenesis and oxidative phosphorylation was observed at the protein level. In contrast, analysis of the The Cancer Genome Atlas (TCGA) papillary RCC cohort revealed no significant change in transcripts encoding oxidative phosphorylation compared to normal kidney tissue, highlighting the importance of proteomic profiling. The molecular characteristics of pRCC are increased GSH synthesis to cope with ROS stress, deficient anabolic glucose synthesis, and compromised oxidative phosphorylation, which could potentially be exploited in innovative anti-cancer strategies
Dissolved Cd, Co, Cu, Fe, Mn, Ni and Zn in the Arctic Ocean
During the Polarstern (PS94) expedition, summer 2015, part of the international GEOTRACES program, sources and sinks of dissolved (D) Cd, Co, Cu, Fe, Mn, Ni and Zn were studied in the central Arctic Ocean. In the Polar Surface Water in which the TransPolar Drift (TPD) is situated, salinity and δ18O derived fractions indicated a distinct riverine source for silicate DCo, DCu, DFe, DMn and DNi. Linear relationships between DMn and the meteoric fraction depended on source distance, likely due to Mn-precipitation during transport. In the upper 50 m of the Makarov Basin, outside the TPD core, DCo, DMn, DNi, DCd and DCu were enriched by Pacific waters, whereas DFe seemed diluted. DCo, DFe, DMn and DZn were relatively high in the Barents Sea and led to enrichment of Atlantic water flowing into the Nansen Basin. Deep concentrations of all metals were significantly lower in the Makarov Basin compared to the Nansen and Amundsen, the Eurasian, Basins. The Gakkel ridge hydrothermal input and higher continental slope convection are explanations for higher metal concentrations in the Eurasian Basins. Although scavenging rates are lower in the Makarov Basin compared to the Eurasian Basins, the residence time is longer and therefore scavenging can decrease the dissolved concentrations with time. This study provides a baseline to assess future change, and additionally identifies processes driving trace metal distributions. Our results underline the importance of fluvial input as well as shelf sources and internal cycling, notably scavenging, for the distribution of bio-active metals in the Arctic Ocean
Das komplexe Beckentrauma: Matching des Beckenregisters DGU mit dem TraumaRegister DGU®
BACKGROUND
Complex pelvic traumas, i.e., pelvic fractures accompanied by pelvic soft tissue injuries, still have an unacceptably high mortality rate of about 18 %.
PATIENTS AND METHODS
We retrospectively evaluated an intersection set of data from the TraumaRegister DGU® and the German Pelvic Injury Register from 2004-2009. Patients with complex and noncomplex pelvic traumas were compared regarding their vital parameters, emergency management, stay in the ICU, and outcome.
RESULTS
From a total of 344 patients with pelvic injuries, 21 % of patients had a complex and 79 % a noncomplex trauma. Complex traumas were significantly less likely to survive (16.7 % vs. 5.9 %). Whereas vital parameters and emergency treatment in the preclinical setting did not differ substantially, patients with complex traumas were more often in shock and showed acute traumatic coagulopathy on hospital arrival, which resulted in more fluid volumes and transfusions when compared to patients with noncomplex traumas. Furthermore, patients with complex traumas had more complications and longer ICU stays.
CONCLUSION
Prevention of exsanguination and complications like multiple organ dysfunction syndrome still pose a major challenge in the management of complex pelvic traumas
Net Charge Fluctuations in Au + Au Interactions at sqrt(s_NN) = 130 GeV
Data from Au + Au interactions at sqrt(s_NN) = 130 GeV, obtained with the
PHENIX detector at RHIC, are used to investigate local net charge fluctuations
among particles produced near mid-rapidity. According to recent suggestions,
such fluctuations may carry information from the Quark Gluon Plasma. This
analysis shows that the fluctuations are dominated by a stochastic distribution
of particles, but are also sensitive to other effects, like global charge
conservation and resonance decays.Comment: 6 pages, RevTeX 3, 3 figures, 307 authors, submitted to Phys. Rev.
Lett. on 21 March, 2002. Plain text data tables for the points plotted in
figures for this and previous PHENIX publications are (will be made) publicly
available at http://www.phenix.bnl.gov/phenix/WWW/run/phenix/papers.htm
Flow Measurements via Two-particle Azimuthal Correlations in Au + Au Collisions at sqrt(s_NN) = 130 GeV
Two particle azimuthal correlation functions are presented for charged
hadrons produced in Au + Au collisions at RHIC sqrt(s_NN) = 130 GeV. The
measurements permit determination of elliptic flow without event-by-event
estimation of the reaction plane. The extracted elliptic flow values v_2 show
significant sensitivity to both the collision centrality and the transverse
momenta of emitted hadrons, suggesting rapid thermalization and relatively
strong velocity fields. When scaled by the eccentricity of the collision zone,
epsilon, the scaled elliptic flow shows little or no dependence on centrality
for charged hadrons with relatively low p_T. A breakdown of this epsilon
scaling is observed for charged hadrons with p_T > 1.0 GeV/c for the most
central collisions.Comment: 6 pages, RevTeX 3, 4 figures, 307 authors, submitted to Phys. Rev.
Lett. on 11 April 2002. Plain text data tables for the points plotted in
figures for this and previous PHENIX publications are (will be made) publicly
available at http://www.phenix.bnl.gov/phenix/WWW/run/phenix/papers.htm
Centrality Dependence of Charged Particle Multiplicity in Au-Au Collisions at sqrt(s_NN)=130 GeV
We present results for the charged-particle multiplicity distribution at
mid-rapidity in Au - Au collisions at sqrt(s_NN)=130 GeV measured with the
PHENIX detector at RHIC. For the 5% most central collisions we find
. The results,
analyzed as a function of centrality, show a steady rise of the particle
density per participating nucleon with centrality.Comment: 307 authors, 43 institutions, 6 pages, 4 figures, 1 table Minor
changes to figure labels and text to meet PRL requirements. One author added:
M. Hibino of Waseda Universit
Event-by-event fluctuations in Mean and Mean in sqrt(s_NN) = 130 GeV Au+Au Collisions
Distributions of event-by-event fluctuations of the mean transverse momentum
and mean transverse energy near mid-rapidity have been measured in Au+Au
collisions at sqrt(s_NN) = 130 GeV at RHIC. By comparing the distributions to
what is expected for statistically independent particle emission, the magnitude
of non-statistical fluctuations in mean transverse momentum is determined to be
consistent with zero. Also, no significant non-random fluctuations in mean
transverse energy are observed. By constructing a fluctuation model with two
event classes that preserve the mean and variance of the semi-inclusive p_T or
e_T spectra, we exclude a region of fluctuations in sqrt(s_NN) = 130 GeV Au+Au
collisions.Comment: 10 pages, RevTeX 3, 7 figures, 4 tables, 307 authors, submitted to
Phys. Rev. C on 22 March 2002. Plain text data tables for the points plotted
in figures for this and previous PHENIX publications are (will be made)
publicly available at
http://www.phenix.bnl.gov/phenix/WWW/run/phenix/papers.htm
Measurement of the mid-rapidity transverse energy distribution from GeV Au+Au collisions at RHIC
The first measurement of energy produced transverse to the beam direction at
RHIC is presented. The mid-rapidity transverse energy density per participating
nucleon rises steadily with the number of participants, closely paralleling the
rise in charged-particle density, such that E_T / N_ch remains relatively
constant as a function of centrality. The energy density calculated via
Bjorken's prescription for the 2% most central Au+Au collisions at
sqrt(s_NN)=130 GeV is at least epsilon_Bj = 4.6 GeV/fm^3 which is a factor of
1.6 larger than found at sqrt(s_NN)=17.2 GeV (Pb+Pb at CERN).Comment: 307 authors, 6 pages, 4 figures, 1 table, submitted to PRL 4/18/2001;
revised version submitted to PRL 5/24/200
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