47 research outputs found

    Implementation of GIS-Based Applications in Water Governance

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    __Abstract__ Geographical Information Systems (GIS) are computer programs that are able to bring large amounts of data of both the physical and the social system together in one comprehensive overview shown digitally. GIS occurred very rapidly on the Dutch policy agenda. In this paper we analyze how the fast introduction process of GIS-based instruments in water management and more specifically in river flood management can be explained. By applying a range of classical models on agenda-setting, we show the important contribution of GIS to the water and flood issue in current spatial planning and policy development in the Netherland

    Chronology of prescribing error during the hospital stay and prediction of pharmacist's alerts overriding: a prospective analysis

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    <p>Abstract</p> <p>Background</p> <p>Drug prescribing errors are frequent in the hospital setting and pharmacists play an important role in detection of these errors. The objectives of this study are (1) to describe the drug prescribing errors rate during the patient's stay, (2) to find which characteristics for a prescribing error are the most predictive of their reproduction the next day despite pharmacist's alert (<it>i.e</it>. override the alert).</p> <p>Methods</p> <p>We prospectively collected all medication order lines and prescribing errors during 18 days in 7 medical wards' using computerized physician order entry. We described and modelled the errors rate according to the chronology of hospital stay. We performed a classification and regression tree analysis to find which characteristics of alerts were predictive of their overriding (<it>i.e</it>. prescribing error repeated).</p> <p>Results</p> <p>12 533 order lines were reviewed, 117 errors (errors rate 0.9%) were observed and 51% of these errors occurred on the first day of the hospital stay. The risk of a prescribing error decreased over time. 52% of the alerts were overridden (<it>i.e </it>error uncorrected by prescribers on the following day. Drug omissions were the most frequently taken into account by prescribers. The classification and regression tree analysis showed that overriding pharmacist's alerts is first related to the ward of the prescriber and then to either Anatomical Therapeutic Chemical class of the drug or the type of error.</p> <p>Conclusions</p> <p>Since 51% of prescribing errors occurred on the first day of stay, pharmacist should concentrate his analysis of drug prescriptions on this day. The difference of overriding behavior between wards and according drug Anatomical Therapeutic Chemical class or type of error could also guide the validation tasks and programming of electronic alerts.</p

    Arachnids of medical importance in Brazil: main active compounds present in scorpion and spider venoms and tick saliva

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    Role of Activity in Defining Metabolic and Contractile Adaptations After SCI

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    International audienceSpinal cord injury (SCI) can lead to moderate to severe muscle paralysis, loss of lower-limb functionality and often results in a reduced physical activity. As a consequence, people with SCI demonstrate numerous metabolic and contractile transformations such as leg muscles atrophy, a transformation from slow, fatigue-resistant fibers to fast, fatigable fibers, a decreased vascularization. Appropriate exercise and most especially exercise using functional electrical stimulation (FES) is now well-known to have beneficial effects on muscle characteristics, force output, exercise capacity, but also bone mineral density and cardiovascular parameters. For example, increases in muscle mass and strength, oxidative capacity and vascularization have been reported after several weeks of FES exercise (FES-strengthening, FES-cycling or FES-rowing) in people with SCI

    A Review on the Recent Advances in the Reductions of Carbon–Carbon/Oxygen Multiple Bonds Including Aromatic Rings Using Raney Ni–Al Alloy or Al Powder in the Presence of Noble Metal Catalysts in Water

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