The supernatural characters and powers of sacred trees in the Holy Land

This article surveys the beliefs concerning the supernatural characteristics and powers of sacred trees in Israel; it is based on a field study as well as a survey of the literature and includes 118 interviews with Muslims and Druze. Both the Muslims and Druze in this study attribute supernatural dimensions to sacred trees which are directly related to ancient, deep-rooted pagan traditions. The Muslims attribute similar divine powers to sacred trees as they do to the graves of their saints; the graves and the trees are both considered to be the abode of the soul of a saint which is the source of their miraculous powers. Any violation of a sacred tree would be strictly punished while leaving the opportunity for atonement and forgiveness. The Druze, who believe in the transmigration of souls, have similar traditions concerning sacred trees but with a different religious background. In polytheistic religions the sacred grove/forest is a centre of the community's official worship; any violation of the trees is regarded as a threat to the well being of the community. Punishments may thus be collective. In the monotheistic world (including Christianity, Islam and Druze) the pagan worship of trees was converted into the worship/adoration of saints/prophets; it is not a part of the official religion but rather a personal act and the punishments are exerted only on the violating individual

Crystal structure of isopenicillin <i>N</i> synthase is the first from a new structural family of enzymes

Penicillin antibiotics are all produced from fermentation-derived penicillins because their chemical synthesis is not commercially viable. The key step in penicillin biosynthesis, in which both the beta-lactam and thiazolidine rings of the nucleus are created, is mediated by isopenicillin N synthase (IPNS), which binds ferrous iron and uses dioxygen as a cosubstrate. In a unique enzymatic step, with no chemical precedent, IPNS catalyses the transfer of four hydrogen atoms from its tripeptide substrate to dioxygen forming, in a single reaction, the complete bicyclic nucleus of the penicillins. We now report the structure of IPNS complexed with manganese, which reveals the active site is unusually buried within a 'jelly-roll' motif and lined by hydrophobic residues, and suggest how this structure permits the process of penicillin formation. Sequence analyses indicate IPNS, 1-aminocyclopropane-1-carboxylic acid oxidase and many of the 2-oxo-acid-dependent oxygenases contain a conserved jelly-roll motif, forming a new structural family of enzymes

Cottoning on to Cotton (Gossypium Spp.) in Arabia and Africa during Antiquity

International audienceThe occurrences of cotton in texts and in the archaeological record (seeds, fibres and textiles) demonstrate the emergence of cotton production centres in north-eastern Africa and western Arabia during the 1st\textendash4th centuries AD, which is concurrent with an increase of cotton trade. These finds could correspond to any of the two Old World domestic cotton species: Gossypium arboreum L., probably domesticated in the Indus valley and traded since the 3rd millennium BC, or Gossypium herbaceum L., an African species about which very little is known, beside its presence in Nubia during Antiquity. Our paper reviews the archaeobotanical, textile and textual data from north-eastern Africa and western Arabia, with specific attention to several sites located in Central Sudan (Muweis), Lower Nubia (Qasr Ibrim), western Egypt (Kellis, Amheida) and north-western Arabia (Madâ'in Sâlih/Hegra). The intention of this review is to a) document how cotton production was integrated into agrarian and trade economies and b) examine current hypotheses regarding the diachronic distribution of the two species. The results highlight the importance of cotton in different agrosystems from the 1st\textendash2nd centuries AD. In Central Sudan, Nubia and Dakhleh oasis, cotton cultivation appeared together with other new tropical/sub-tropical crops, such as sorghum ( Sorghum bicolor) and pearl millet (Pennisetum glaucum subsp. glaucum). This was not the case in north-western Arabia. It seems that cotton production occurred at first as small-scale experiments before scaling up during the 3rd century AD, in conjunction with the spread of the water-wheel in the Nile valley. Cotton in Nubia, and possibly in other neighbouring areas, probably belonged to the African species G. herbaceum, which was in all likelihood domesticated in southern regions, perhaps Ethiopia. We suggest that the increase of exchanges across the Indian Ocean during Antiquity created a favourable context for the emergence of cotton production and its relative expansion before the Islamic period