Children’s coping styles and trauma symptoms after an explosion disaster

Background: The negative impact of trauma on children and adolescents is well documented. However, few studies have investigated the relationship between coping and trauma and distress symptoms after man-made disasters, especially those not related to war. Objective: This study investigated the relationship between children’s coping styles and their self-reported levels of trauma and distress symptoms after an explosion disaster in a residential area. Method: Participants were recruited through the local public school that served the affected residential area. A total of 333 children and adolescents from grades 3 through 10 participated in the study 16 months after the explosion. All participants filled out questionnaires to assess their trauma and distress symptoms as well as their coping strategies. The adolescents answered additional questions about pre-, peri-, and post-traumatic factors and filled out questionnaires about their trauma and distress symptoms, including aspects of somatization and negative affectivity. Results: The following variables were associated with a higher degree of trauma symptoms for children in grades 6 through 10 and explained 39% to 48% of the unique variance in these symptoms: female gender; the experience of traumatic events pre-disaster; the destruction of property or danger to life occurring during the disaster; the experience of traumatic events post-disaster; and the use of self-blame, emotion regulation, wishful thinking, and cognitive restructuring. For the younger children, pre-, peri-, and post-disaster factors were not measured. However, female gender and the use of self-blame as a coping strategy explained 26% of the variance in trauma symptoms. Conclusions: This study generally supports the findings of the limited literature addressing coping skills after man-made disasters. However, contrary to previous findings in community samples after episodes of terrorism, adaptive coping strategies such as cognitive restructuring were found to influence the variance of trauma and distress symptoms

Caracterização da pastagem nativa de ?Zona de Mimoso? diferida, em Campo Maior, PI.

O presente trabalho objetivou avaliar o estrato herbáceo da pastagem nativa do tipo vegetacional em Campo Maior, PI, na transição entre períodos chuvoso e seco, em área vedada ao pastejo

Efeito do diferimento sobre características bromatológicas do estrato herbáceo de pastagem nativa de "Zona de Mimoso" na estação seca.

O tipo vegetacional ?Zona de Mimoso? constitui a base da alimentação dos rebanhos do município piauiense de Campo Maior. Avaliou-se o efeito do diferimento sobre características bromatológicas do estrato herbáceo da pastagem nativa de "Zona de Mimoso" em Campo Maior, PI, durante o período de estiagem

Zoneamento Agroecológico do município de Bonito/MS.

A Embrapa Solos em parceria com a Secretaria de Estado de Desenvolvimento Agrário, da Produção, da Indústria, do Comércio e do Turismo - SEPROTUR realizou o Zoneamento Agroecológico do Estado do Mato Grosso do Sul ? Fase I - com objetivo de contribuir na indicação de áreas passíveis de exploração agrícola sustentável. No desenvolvimento desse trabalho foram considerados aspectos legais, restrições ambientais, potencial das culturas, aspectos do clima, de geomorfologia e dos solos. Esses parâmetros estão integrados em ambiente de sistema de informação geográfica com apoio de algebra de mapas, no intuito de avaliar a adequabilidade de uso das terras e apresentar uma proposição de planejamento de uso e ocupação das terras. Os resultados desse trabalho foram consolidados por município e dão origem a esse boletim de pesquisa. As terras indicadas para o uso com lavouras somam cerca de 280.000 ha, correspondendo a aproximadamente 66,5% da área total do município, enquanto que as recomendadas equivalentem a 22,7% e as áreas recomendadas para pastagem especial ou cultivo de arroz correspondem a aproximadamente 8% da área do município que corresponde a algo como 40.000 hectares. Nestas unidades é fundamental avaliar-se criteriosamente a utilização de pastagens nestas terras quando essas ainda se encontram sob cobertura vegetal, visto que, praticamente 50% destas terras ainda permanecem com vegetação natural em seus diversos graus de conservação. As terras recomendadas para conservação dos recursos naturais e/ou recuperação ambiental somam quase 30.000 ha, as quais constituem áreas de alta fragilidade ambiental e/ou apresentam restrições legais de uso como áreas de preservação permanente.bitstream/item/103010/1/BPD-145-Bonito-MS.pd

Reprogramming energy metabolism and inducing angiogenesis : co-expression of monocarboxylate transporters with VEGF family members in cervical adenocarcinomas

Background: Deregulation of cellular energetic metabolism was recently pointed out as a hallmark of cancer cells. This deregulation involves a metabolic reprogramming that leads to a high production of lactate. Lactate efflux, besides contributing for the glycolytic flux, also acts in the extracellular matrix, contributing for cancer malignancy, by, among other effects, induction of angiogenesis. However, studies on the interplay between cancer metabolism and angiogenesis are scarce. Therefore, the aim of the present study was to evaluate the metabolic and vascular molecular profiles of cervical adenocarcinomas, their co-expression, and their relation to the clinical and pathological behavior. Methods: The immunohistochemical expression of metabolism-related proteins (MCT1, MCT4, CD147, GLUT1 and CAIX) as well as VEGF family members (VEGF-A, VEGF-C, VEGF-D, VEGFR-1, VEGFR-2 and VEGFR-3) was assessed in a series of 232 cervical adenocarcinomas. The co-expression among proteins was assessed and the expression profiles were associated with patients’ clinicopathological parameters. Results: Among the metabolism-related proteins, MCT4 and CAIX were the most frequently expressed in cervical adenocarcinomas while CD147 was the less frequently expressed protein. Overall, VEGF family members showed a strong and extended expression with VEGF-C and VEGFR-2 as the most frequently expressed and VEGFR-1 as the less expressed member. Co-expression of MCT isoforms with VEGF family members was demonstrated. Finally, MCT4 was associated with parametrial invasion and HPV18 infection, CD147 and GLUT1 with distant metastasis, CAIX with tumor size and HPV18 infection, and VEGFR-1 with local and lymphnode metastasis. Conclusions: The results herein presented provide additional evidence for a crosstalk between deregulating cellular energetics and inducing angiogenesis. Also, the metabolic remodeling and angiogenic switch are relevant to cancer progression and aggressiveness in adenocarcinomas.CP received a post-doctoral fellowship (SFRH/BPD/69479/2010) and FM-S received a doctoral fellowship (SFRH/BD/87139/2012) from FCT (Portuguese Foundation for Science and Technology). This work was supported by the FCT grant ref. PTDC/SAU-FCF/104347/2008, under the scope of "Programa Operacional Tematico Factores de Competitividade" (COMPETE) of "Quadro Comunitario de Apoio III" and co-financed by Fundo Comunitario Europeu FEDER, and also by FAPESP 2008/03232-1

Zoneamento Agroecológico do município de Guia Lopes da Laguna - MS.

bitstream/item/25441/1/bpd146-2009-guia-lopes-ms.pd

Efeito do diferimento na avaliação dos teores de matéria seca (MS) e proteína bruta (PB) do estrato herbáceo de pastagem nativa de "Zona de Mimoso", na transição estação chuvosa e seca.

O presente trabalho objetivou avaliar o efeito do diferimento sobre características bromatológicas do estrato herbáceo da pastagem nativa de "Zona de Mimoso", no município de Campo Maior, PI, no período de transição entre as estações chuvosa e seca

1,3-Dicyclo­hexyl-3-[(pyridin-2-yl)carbon­yl]urea monohydrate from synchrotron radiation

The title urea derivative crystallizes as a monohydrate, C19H27N3O2·H2O. The central C3N grouping is almost planar (r.m.s. deviation = 0.0092 Å), and the amide and pyridine groups are substanti­ally twisted out this plane [dihedral angles = 62.80 (12) and 34.98 (10)°, respectively]. Supra­molecular double chains propagating along the b-axis direction feature in the crystal packing whereby linear chains sustained by N—H⋯O hydrogen bonds formed between the amide groups are linked by helical chains of water mol­ecules (linked by O—H⋯O hydrogen bonds). The H atom that participates in these water chains is disordered over two positions of equal occupancy. The double chains are connected into a two-dimensional array by C—H⋯O contacts and the layers stack along the a axis