31 research outputs found

    Risk profiles and one-year outcomes of patients with newly diagnosed atrial fibrillation in India: Insights from the GARFIELD-AF Registry.

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    BACKGROUND: The Global Anticoagulant Registry in the FIELD-Atrial Fibrillation (GARFIELD-AF) is an ongoing prospective noninterventional registry, which is providing important information on the baseline characteristics, treatment patterns, and 1-year outcomes in patients with newly diagnosed non-valvular atrial fibrillation (NVAF). This report describes data from Indian patients recruited in this registry. METHODS AND RESULTS: A total of 52,014 patients with newly diagnosed AF were enrolled globally; of these, 1388 patients were recruited from 26 sites within India (2012-2016). In India, the mean age was 65.8 years at diagnosis of NVAF. Hypertension was the most prevalent risk factor for AF, present in 68.5% of patients from India and in 76.3% of patients globally (P < 0.001). Diabetes and coronary artery disease (CAD) were prevalent in 36.2% and 28.1% of patients as compared with global prevalence of 22.2% and 21.6%, respectively (P < 0.001 for both). Antiplatelet therapy was the most common antithrombotic treatment in India. With increasing stroke risk, however, patients were more likely to receive oral anticoagulant therapy [mainly vitamin K antagonist (VKA)], but average international normalized ratio (INR) was lower among Indian patients [median INR value 1.6 (interquartile range {IQR}: 1.3-2.3) versus 2.3 (IQR 1.8-2.8) (P < 0.001)]. Compared with other countries, patients from India had markedly higher rates of all-cause mortality [7.68 per 100 person-years (95% confidence interval 6.32-9.35) vs 4.34 (4.16-4.53), P < 0.0001], while rates of stroke/systemic embolism and major bleeding were lower after 1 year of follow-up. CONCLUSION: Compared to previously published registries from India, the GARFIELD-AF registry describes clinical profiles and outcomes in Indian patients with AF of a different etiology. The registry data show that compared to the rest of the world, Indian AF patients are younger in age and have more diabetes and CAD. Patients with a higher stroke risk are more likely to receive anticoagulation therapy with VKA but are underdosed compared with the global average in the GARFIELD-AF. CLINICAL TRIAL REGISTRATION-URL: http://www.clinicaltrials.gov. Unique identifier: NCT01090362

    Groei en produksie van 'n aantal aangeplante weidings onder beweiding.

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    The growth and production of a number of cultivated pasture species in the grazed condition, were measured by means of the difference method. From the data obtained in the trial it became clear that green material can be supplied right through the year if there is possibility of irrigationLanguage: AfrikaansKeywords: Continuous grazing; Cultivated pastures; Dry-land; Exclosures; Irrigation; Subtropical species; Temperate specie

    A comparison of pasture and fodder crops for the production of slaughter lambs in the Pretoria-Witwatersrand-Vereeniging (PWV) area.

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    A number of pasture and fodder species were evaluated for the production of mutton with weaner lambs. Animal performance and meat production under three stocking rates, which were classified as light, medium, and heavy, were obtained with the aim of identifying best pasture/fodder for every season. The pastures/fodders included were Lolium multiflorum cv. Midmar and Triticum x Secale pastures under irrigation. Avena sativa and Vicia dasycarpa pasture mixture and maize crop residues under rainfed conditions and Medicago sativa and Digitaria eriantha hay for the winter months. The spring pastures were L. multiflorum cv. Midmar, Lolium perenne cv. Nui and Dactylis glomerata cv. Hera under irrigation, while the summer pastures included Digitaria eriantha var. eriantha and M. sativa cv. Cuf 101 pastures under rainfed conditions and Cynodon dactylon cv. NK37 under irrigation. Of these, the Midmar pasture for the winter and spring, maize crop residues for the winter, Hera for the spring and Cuf 101 for the summer seemed to be the best pasture of those tested in their season of use, from an animal production point of view.Keywords: afrikaans; animal performance; animal production; avena sativa; cynodon dactylon; dactylis glomerata; digitaria eriantha; fodder; hay; lambs; lolium multiflorum; lolium perenne; maize; meat production; medicago sativa; pastures; performance; rainfed condition; seasonal production; south africa; stocking rate; stocking rates; university of pretoria; vicia dasycarp

    Short Communication:A technique to quantify available above-ground phytomass of grass tufts in defoliation studies.

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    A technique to quantify available above-ground phytomass of grass tufts in defoliation studies is described. Highly significant correlations were found between tuft volume and above-ground phytomass in eighteen out of twenty-two species that were examined. Tuft volume can therefore be used to calculate the above-ground phytomass of a tuft. This can then be used to obtain a more objective description of utilization. The determination of the relative percentage utilization is based on the percentage material removed from a known amount.Keywords: above-ground phytomass; defoliation; grasses; growth form; leaf distribution; percentage utilization; phytomass; standing matter availability; technique; tufts; utilizatio
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