3,723 research outputs found
A Framework for the Principled Debugging of Prolog Programs: How to Debug Non-Terminating Programs
Jensen-Feynman approach to the statistics of interacting electrons
Faussurier et al. [Phys. Rev. E 65, 016403 (2001)] proposed to use a
variational principle relying on Jensen-Feynman (or Gibbs-Bogoliubov)
inequality in order to optimize the accounting for two-particle interactions in
the calculation of canonical partition functions. It consists in a
decomposition into a reference electron system and a first-order correction.
The procedure appears to be very efficient in order to evaluate the free energy
and the orbital populations. In this work, we present numerical applications of
the method and propose to extend it using a reference energy which includes the
interaction between two electrons inside a given orbital. This is possible
thanks to our efficient recursion relation for the calculation of partition
functions. We also show that a linear reference energy, however, is usually
sufficient to achieve a good precision and that the most promising way to
improve the approach of Faussurier et al. is to apply Jensen's inequality to a
more convenient convex function.Comment: submitted to Physical Review
Photometry of supernovae in an image series : methods and application to the Supernova Legacy Survey (SNLS)
We present a technique to measure lightcurves of time-variable point sources
on a spatially structured background from imaging data. The technique was
developed to measure light curves of SNLS supernovae in order to infer their
distances. This photometry technique performs simultaneous PSF photometry at
the same sky position on an image series. We describe two implementations of
the method: one that resamples images before measuring fluxes, and one which
does not. In both instances, we sketch the key algorithms involved and present
the validation using semi-artificial sources introduced in real images in order
to assess the accuracy of the supernova flux measurements relative to that of
surrounding stars. We describe the methods required to anchor these PSF fluxes
to calibrated aperture catalogs, in order to derive SN magnitudes. We find a
marginally significant bias of 2 mmag of the after-resampling method, and no
bias at the mmag accuracy for the non-resampling method. Given surrounding star
magnitudes, we determine the systematic uncertainty of SN magnitudes to be less
than 1.5 mmag, which represents about one third of the current photometric
calibration uncertainty affecting SN measurements. The SN photometry delivers
several by-products: bright star PSF flux mea- surements which have a
repeatability of about 0.6%, as for aperture measurements; we measure relative
astrometric positions with a noise floor of 2.4 mas for a single-image bright
star measurement; we show that in all bands of the MegaCam instrument, stars
exhibit a profile linearly broadening with flux by about 0.5% over the whole
brightness range.Comment: Accepted for publication in A&A. 20 page
Higher-order conservative interpolation between control-volume meshes: Application to advection and multiphase flow problems with dynamic mesh adaptivity
© 2016 .A general, higher-order, conservative and bounded interpolation for the dynamic and adaptive meshing of control-volume fields dual to continuous and discontinuous finite element representations is presented. Existing techniques such as node-wise interpolation are not conservative and do not readily generalise to discontinuous fields, whilst conservative methods such as Grandy interpolation are often too diffusive. The new method uses control-volume Galerkin projection to interpolate between control-volume fields. Bounded solutions are ensured by using a post-interpolation diffusive correction. Example applications of the method to interface capturing during advection and also to the modelling of multiphase porous media flow are presented to demonstrate the generality and robustness of the approach
Pulsed mononode dye laser developed for a geophysical application
Following the extension of the lidar technique in the study of the atmosphere, the necessity of having a high power pulsed laser beam with a narrowed bandwidth and the possibility of selecting a particular wavelength within a certain spectral region arises. With the collaboration of others, a laser cavity using the multiwave Fizeau wedge (MWFW) was developed. Using the classical method of beam amplification with the aid of different stages, a new pulsed dye laser device was designed. The originality resides in the use of reflecting properties of the MFWF. Locally a plan wave coming with a particular angular incidence is reflected with a greater than unity coefficient; this is the consequence of the wedge angle which doubles the participation of every ray in the interferometric process. This dye laser operation and advantages are discussed. The feasibility of different geophysical applications envisageable with this laser is discussed
Genesis of ancestral haplotypes: RNA modifications and reverse transcription–mediated polymorphisms
Understanding the genesis of the block haplotype structure of the genome is a major challenge. With the completion of the sequencing of the Human Genome and the initiation of the HapMap project the concept that the chromosomes of the mammalian genome are a mosaic, or patchwork, of conserved extended block haplotype sequences is now accepted by the mainstream genomics research community. Ancestral Haplotypes (AHs) can be viewed as a recombined string of smaller Polymorphic Frozen Blocks (PFBs). How have such variant extended DNA sequence tracts emerged in evolution? Here the relevant literature on the problem is reviewed from various fields of molecular and cell biology particularly molecular immunology and comparative and functional genomics. Based on our synthesis we then advance a testable molecular and cellular model. A critical part of the analysis concerns the origin of the strand biased mutation signatures in the transcribed regions of the human and higher primate genome, A-to-G versus T-to-C (ratio ~1.5 fold) and C-to-T versus G-to-A (≥1.5 fold). A comparison and evaluation of the current state of the fields of immunoglobulin Somatic Hypermutation (SHM) and Transcription-Coupled DNA Repair focused on how mutations in newly synthesized RNA might be copied back to DNA thus accounting for some of the genome-wide strand biases (e.g., the A-to-G vs T-to-C component of the strand biased spectrum). We hypothesize that the genesis of PFBs and extended AHs occurs during mutagenic episodes in evolution (e.g., retroviral infections) and that many of the critical DNA sequence diversifying events occur first at the RNA level, e.g., recombination between RNA strings resulting in tandem and dispersed RNA duplications (retroduplications), RNA mutations via adenosine-to-inosine pre-mRNA editing events as well as error prone RNA synthesis. These are then copied back into DNA by a cellular reverse transcription process (also likely to be error-prone) that we have called "reverse transcription-mediated long DNA conversion." Finally we suggest that all these activities and others can be envisaged as being brought physically under the umbrella of special sites in the nucleus involved in transcription known as "transcription factories."
- …