36 research outputs found

    Sexual networking, STDs and HIV/AIDS in four urban gaols in Nigeria

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    Truck drivers, female hawkers and prostitutes are generally regarded as high-risk groups because they have a high rate of partner change, run abnormally high risks of being infected with sexually transmitted diseases (STDs) including HIV/AIDS, and are capable of transmitting them to the general population who live around them (Orubuloye, Caldwell and Caldwell 1993; Orubuloye 1995). Recent experience has shown that the prison population runs a high risk of being engulfed by AIDS. By late 1992, HIV-positive prisoners had been detected in at least one of the prisons in Nigeria and there was beginning to be concern for the safety of the prison population. Therefore a study of the prison population was planned as part of a larger continuing research program of the Ondo State University, Ado-Ekiti, Nigeria, on Sexual Networking, STDs and HIV/AIDS Transmission, supported by a grant from the Swedish Agency for Research Cooperation with Developing Countries (SAREC). The aim of the prison study was to investigate the attitudes and activities that are likely to facilitate the spread of sexually transmitted diseases, HIV and AIDS; and to develop an intervention program for the prison population and any population that may be in a similar situation

    Effects of Na2Cr2O7 Inhibitor on the Corrosion Potential Response of Steel Reinforced Concrete in Saline Medium

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    Electrochemical monitoring method of the open circuit potential was used to investigate the effect of the concentrations of Na2Cr2O7 on the corrosion potential response of steel reinforced concrete in sodium chloride medium. In the study, five different concentrations of Na2Cr2O7 admixtures were employed in a system of replicated samples of steel-reinforced concrete specimens partially immersed in 3.5% NaCl to simulate marine and saline environments. Forty days measured responses from these were subjected to the statistical analyses of the Normal and the Weibull distribution functions and tested using the Kolmogorov-Smirnov goodness of fit criteria. Results obtained from the analyses identified 4 g Na2Cr2O7 with optimal averaged potential response inhibition performance by the Normal model which showed better agreements in its models of Na2Cr2O7 potential test data than that obtained from the Weibull model of the same data. These bear pertinent implications on the need for suitability studies of appropriate statistical distribution for studying performance of corrosion inhibitors even as suggestions were proffered for addressing results conflicts among replicates of steel reinforced concrete samples employed

    METHODS OF ASTM G16 AND CONFLICTS IN CORROSION TEST DATA: CASE STUDY OF NANO2 EFFECTIVENESS ON STEEL-REBAR CORROSION

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    In this paper, applications of the methods of ASTM G16 for addressing inherent conflicts in laboratory measurements of corrosion test data were studied, using the inhibiting effect of NaNO2 on the corrosion of concrete steel-rebar for the case study. For this, electrochemical monitoring techniques were employed for studying effectiveness of different concentrations of NaNO2 admixture in replicated concrete samples immersed in NaCl and in H2SO4 media for an experimental period of sixty-eight days. The corrosion test data from this experimental setup were subjected to the probability density fittings of the Normal and the Weibull functions as well as to significance testing methods of ASTM G16-99 R04 specifications. Results identified 10g (0.1208M) NaNO2 admixture with optimal inhibition efficiency model, η = 88.38±4.62%, in the saline/marine simulating environment and the 8 g (0.0966M) NaNO2 admixture with optimum effectiveness, η = 13.51±83.48%, in the acidic environment. The techniques of ASTM G16 adequately identified and addressed conflicting effectiveness from the test data of NaNO2 admixtures in the studied test environments

    Effectiveness of Treatment Outcomes of Public Private Mix Tuberculosis Control Program in Eastern Nigeria

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    Effective tuberculosis treatment has been shown to have significant effect on the control of tuberculosis. Completion of treatment of active cases is therefore the most important priority of tuberculosis control programmes. Descriptive statistics with a retrospective cohort study design used to analyze secondary data set (2007-2010) of patients accessing TB-DOTS treatment in two facilities (Nnamdi Azikiwe University Teaching Hospital, NAUTH and Department of Health Services Tuberculosis and Leprosy  Control Unit Nnewi North Local Government Area (L.G.A.) Secretariat, DHSTLCU ) as public health facilities and other two facilities ( Immaculate Heart of Catholic Church Hospital, IHCCH  and Diocesan Anglican Communion Hospital, DACH) as private health facilities in Nnewi North L.G.A., Anambra State. Gender of patients were male: female 54%(1016 patients) : 46% (883 patients) and 53%(63 patients) : 47%(56 patients) in public and private health facilities respectively . Using WHO (1996) standards the health facilities adjudged as efficient were: in 2007, private facilities using the indicator  of treatment failure rate; private facilities using the indicator of death rate;  public facilities and private facilities using  the indicator of transfer-out rate ; public facilities using the indicator of  treatment completion rate. In 2008, effective health facilities were: private health facilities using the indicator of failure rate; public and private health facilities using the indicator of transfer-out rate; private facilities using the indicator of treatment completion rate. In 2009, effective health facilities were public and private health facilities using indicator of treatment failure rate; public and private health facilities using the indicator of death rate; public and private facilities using the indicator of transfer out; public and private facilities using the indicator of treatment completion rate. In 2010, effective health facilities were: private health facilities using the indicator of  cure rate; private facilities using the indicator of death rate ; public and private facilities using the indicator of transfer-out; public facilities using the indicator of treatment completion rate. In conclusion, private health facilities were more effective than public health facilities  by the several indicators over the four year period.  Future research is needful to use primary and secondary data sets in assessment of TB control program effectiveness; technical efficiency assessment using non-parametric statistics will assess the validity of assessing effectiveness using only the WHO standards; identify centre-specific factors associated with poor treatment outcome; institutionalizing a reward system for effective TB-DOTS facilities will engender healthy competition in the Public Private Mix for sustained effectiveness; the Monitoring and Evaluation tools especially the treatment card for data capture should be improved upon for comprehensiveness of patients socio-economic history. Keywords: Tuberculosis, Effectiveness, Treatments Outcomes, Public Private Mi

    Nanochitosan derived from marine bacteria

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    Nanochitosans are polysaccharides produced by the alkalescent deacetylation of chitin and comprise a series of 2-deoxy-2 (acetylamino) glucose linked by ß-(1-4) glycosidic linkages. These are naturally formed from the deacetylation of shellfish shells and the exoskeleton of aquatic arthropods and crustaceans. Reports of chitosan production from unicellular marine bacteria inhabiting the sea, and possessing distinct animal- and plant-like characteristics abound. This capacity to synthesize chitosan from chitin arises from response to stress under extreme environmental conditions, as a means of survival. Consequently, the microencapsulation of these nanocarriers results in new and improved chitosan nanoparticles, nanochitosan. This nontoxic bioactive material which can serve as an antibacterial agent, gene delivery vector as well as carrier for protein and drug release as compared with chitosan, is limited by its nonspecific molecular weight and higher composition of deacetylated chitin. This chapter highlights the biology and diversity of nanochitosan-producing marine bacteria, including the factors influencing their activities, survival, and distribution. More so, the applications of marine bacterial nanochitosans in transfection and gene delivery; wound healing and drug delivery; feed supplement development and antimicrobial activity are discussed

    Next Generation Nanochitosan Applications in Animal Husbandry, Aquaculture and Food Conservation

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    Studies have identified the properties of enzymes, functionalized molecules, and compounds in food industry applications as edible coatings and encapsulations, that assure prolonged food quality and standards. These molecules present benefits of longer shelf-life by delayed deterioration and inhibition of the proliferation of spoilage and mycotoxigenic microorganisms. However, challenges of reduced nutrient levels, miniaturized size, and low chemical stability remain concerning. Chitosan polymers naturally formed from the deacetylation of shellfish shells and exoskeletons of aquatic arthropods and crustaceans offer improved benefits when functionalized into nanoparticles as nanochitosans. These polysaccharides produced by the alkalescent deacetylation of chitin, comprise a series of 2-deoxy-2 (acetylamino) glucose linked by ß-(1- 4) glycosidic linkages. This chapter considers the health impacts and microbiological health hazards associated with animal feeds quality and the enzyme immobilization potentials of nanochitosans in animalbased food and feed packages. Thereafter, nanochitosan properties and benefits are compared against traditional preservatives from microbes and plants; with highlights on current challenges in the application of nanochitosan for enzyme immobilization

    Chapter 21 - Utilization of nanochitosan in the sterilization of ponds and water treatment for aquaculture

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    Water pollution constitutes the leading cause of infant mortality, neonatal deformities, and shrinkage of man’s average life expectancy. Pollutants come from point and nonpoint sources; and water pollution arises from the discharge of wastewater containing undesirable impurities used for domestic, agricultural, and industrial purposes. More so, high nutrient and wastewater runoffs from fish production systems contribute to the fouling and eutrophication of recipient water bodies. Hence, aquaculture which is inextricably linked to the natural environment is challenged by the dearth of appropriate water quantity and quality, militating against fish, and fishery production. Nanochitosans as polysaccharides produced by the alkalescent deacetylation of chitin, comprise a series of 2-deoxy-2 (acetylamino) glucose linked by ß-(1-4) glycosidic linkages. They are naturally formed from the deacetylation of shellfish shells and exoskeletons of aquatic arthropods and crustaceans. The unique attributes of chitin confer a wide range of biotechnological applications on the polymer, observed in flocculation as a wastewater treatment and purification route initiated by chitosan. This chapter highlights nanochitosan properties of aquaculture relevance; and elucidates the purification potentials of nanochitosan, compared to inorganic coagulants and organic polymeric flocculants. Effects of chitosan on contaminants and microorganisms, as well as applications in fish pathogens detection, fish disease diagnosis, and control are discussed

    Utilization of nanochitosan in the sterilization of ponds and water treatment for aquaculture

    Get PDF
    Water pollution constitutes the leading cause of infant mortality, neonatal deformities, and shrinkage of man’s average life expectancy. Pollutants come from point and nonpoint sources; and water pollution arises from the discharge of wastewater containing undesirable impurities used for domestic, agricultural, and industrial purposes. More so, high nutrient and wastewater runoffs from fish production systems contribute to the fouling and eutrophication of recipient water bodies. Hence, aquaculture which is inextricably linked to the natural environment is challenged by the dearth of appropriate water quantity and quality, militating against fish, and fishery production. Nanochitosans as polysaccharides produced by the alkalescent deacetylation of chitin, comprise a series of 2-deoxy-2 (acetylamino) glucose linked by ß-(1-4) glycosidic linkages. They are naturally formed from the deacetylation of shellfish shells and exoskeletons of aquatic arthropods and crustaceans. The unique attributes of chitin confer a wide range of biotechnological applications on the polymer, observed in flocculation as a wastewater treatment and purification route initiated by chitosan. This chapter highlights nanochitosan properties of aquaculture relevance; and elucidates the purification potentials of nanochitosan, compared to inorganic coagulants and organic polymeric flocculants. Effects of chitosan on contaminants and microorganisms, as well as applications in fish pathogens detection, fish disease diagnosis, and control are discussed

    Utilization of nanochitosan for enzyme immobilization of aquatic and animal-based food packages

    Get PDF
    Studies have identified the properties of enzymes, functionalized molecules, and compounds in food industry applications as edible coatings and encapsulations, that assure prolonged food quality and standards. These molecules present benefits of longer shelf-life by delayed deterioration and inhibition of the proliferation of spoilage and mycotoxigenic microorganisms. However, challenges of reduced nutrient levels, miniaturized size, and low chemical stability remain concerning. Chitosan polymers naturally formed from the deacetylation of shellfish shells and exoskeletons of aquatic arthropods and crustaceans offer improved benefits when functionalized into nanoparticles as nanochitosans. These polysaccharides produced by the alkalescent deacetylation of chitin, comprise a series of 2-deoxy-2 (acetylamino) glucose linked by ß-(1-4) glycosidic linkages. This chapter considers the health impacts and

    Nanochitosan derived from marine bacteria

    Get PDF
    Nanochitosans are polysaccharides produced by the alkalescent deacetylation of chitin and comprise a series of 2‐deoxy‐2 (acetylamino) glucose linked by ß‐(1‐4) glycosidic linkages. These are naturally formed from the deacetylation of shellfish shells and the exoskeleton of aquatic arthropods and crustaceans. Reports of chitosan production from unicellular marine bacteria inhabiting the sea, and possessing distinct animal‐ and plant‐like characteristics abound. This capacity to synthesize chitosan from chitin arises from response to stress under extreme environmental conditions, as a means of survival. Consequently, the microencapsulation of these nanocarriers results in new and improved chitosan nanoparticles, nanochitosan. This nontoxic bioactive material which can serve as an antibacterial agent, gene delivery vector as well as carrier for protein and drug release as compared with chitosan, is limited by its nonspecific molecular weight and higher composition of deacetylated chitin. This chapter highlights the biology and diversity of nanochitosan‐producing marine bacteria, including the factors influencing their activities, survival, and distribution. More so, the applications of marine bacterial nanochitosans in transfection and gene delivery; wound healing and drug delivery; feed supplement development and antimicrobial activity are discussed
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