632 research outputs found
Controlling the transport of an ion: Classical and quantum mechanical solutions
We investigate the performance of different control techniques for ion
transport in state-of-the-art segmented miniaturized ion traps. We employ
numerical optimization of classical trajectories and quantum wavepacket
propagation as well as analytical solutions derived from invariant based
inverse engineering and geometric optimal control. We find that accurate
shuttling can be performed with operation times below the trap oscillation
period. The maximum speed is limited by the maximum acceleration that can be
exerted on the ion. When using controls obtained from classical dynamics for
wavepacket propagation, wavepacket squeezing is the only quantum effect that
comes into play for a large range of trapping parameters. We show that this can
be corrected by a compensating force derived from invariant based inverse
engineering, without a significant increase in the operation time
Errors in quantum optimal control and strategy for the search of easily implementable control pulses
We introduce a new approach to assess the error of control problems we aim to
optimize. The method offers a strategy to define new control pulses that are
not necessarily optimal but still able to yield an error not larger than some
fixed a priori threshold, and therefore provide control pulses that might be
more amenable for an experimental implementation. The formalism is applied to
an exactly solvable model and to the Landau-Zener model, whose optimal control
problem is solvable only numerically. The presented method is of importance for
applications where a high degree of controllability of the dynamics of quantum
systems is required.Comment: 13 pages, 3 figure
Precise method for the determination of the neutron electric form factor based on a relativistic analysis of the process $d(e,e'n)p
We generalize the recoil polarization method for the determination of the
proton form factor to the case of the disintegration of vector polarized
deuterons by longitudinally polarized electrons, . We
suggest to measure for this reaction, in the kinematics of quasi-elastic
-scattering, the ratio of the asymmetries induced by the
- and -components of the deuteron vector polarization. In the framework
of the relativistic impulse approximation the ratio is sensitive to
in a wide interval of momentum transfer squared, whereas it depends
weakly on the details of the -interaction and on the choice of the deuteron
wave function. Moreover, in the range 1.5 GeV, the ratio
shows a smooth dependence on , making the analysis simpler.Comment: 7 pages, 4 figs, 1 tabl
Quantum computing implementations with neutral particles
We review quantum information processing with cold neutral particles, that
is, atoms or polar molecules. First, we analyze the best suited degrees of
freedom of these particles for storing quantum information, and then we discuss
both single- and two-qubit gate implementations. We focus our discussion mainly
on collisional quantum gates, which are best suited for atom-chip-like devices,
as well as on gate proposals conceived for optical lattices. Additionally, we
analyze schemes both for cold atoms confined in optical cavities and hybrid
approaches to entanglement generation, and we show how optimal control theory
might be a powerful tool to enhance the speed up of the gate operations as well
as to achieve high fidelities required for fault tolerant quantum computation.Comment: 19 pages, 12 figures; From the issue entitled "Special Issue on
Neutral Particles
Fabrication of a planar micro Penning trap and numerical investigations of versatile ion positioning protocols
We describe a versatile planar Penning trap structure, which allows to
dynamically modify the trapping conguration almost arbitrarily. The trap
consists of 37 hexagonal electrodes, each with a circumcirle-diameter of 300 m,
fabricated in a gold-on-sapphire lithographic technique. Every hexagon can be
addressed individually, thus shaping the electric potential. The fabrication of
such a device with clean room methods is demonstrated. We illustrate the
variability of the device by a detailed numerical simulation of a lateral and a
vertical transport and we simulate trapping in racetrack and articial crystal
congurations. The trap may be used for ions or electrons, as a versatile
container for quantum optics and quantum information experiments.Comment: 10 pages, 7 figures, pdflatex, to be published in New Journal of
Physics (NJP) various changes according to the wishes of the NJP referees.
Text added and moved around, title changed, abstract changed, references
added rev3: one reference had a typo (ref 15), fixed (phys rev a 72, not 71
tBid induces alterations of mitochondrial fatty acid oxidation flux by malonyl-CoA-independent inhibition of carnitine palmitoyltransferase-1.
Recent studies suggest a close relationship between cell metabolism and apoptosis. We have evaluated changes in lipid metabolism on permeabilized hepatocytes treated with truncated Bid (tBid) in the presence of caspase inhibitors and exogenous cytochrome c. The measurement of b-oxidation flux by labeled palmitate demonstrates that tBid inhibits b-oxidation, thereby resulting in the accumulation of palmitoyl-coenzyme A (CoA) and depletion of acetyl-carnitine and acylcarnitines, which is pathognomonic for inhibition of carnitine palmitoyltransferase-1 (CPT-1). We also show that tBid decreases CPT-1 activity by a mechanism independent of both malonyl-CoA, the key inhibitory molecule of CPT-1, and Bak and/or Bax, but
dependent on cardiolipin decrease. Overexpression of Bcl-2, which is able to interact with CPT-1, counteracts the effects exerted by tBid on b-oxidation. The unexpected role of tBid in the regulation of lipid b-oxidation suggests a model in which tBid-induced metabolic decline leads to the accumulation of toxic lipid metabolites such as palmitoyl-CoA, which might become participants in the apoptotic pathway
Focusing a deterministic single-ion beam
We focus down an ion beam consisting of single 40Ca+ ions to a spot size of a
few mum using an einzel-lens. Starting from a segmented linear Paul trap, we
have implemented a procedure which allows us to deterministically load a
predetermined number of ions by using the potential shaping capabilities of our
segmented ion trap. For single-ion loading, an efficiency of 96.7(7)% has been
achieved. These ions are then deterministically extracted out of the trap and
focused down to a 1sigma-spot radius of (4.6 \pm 1.3)mum at a distance of 257mm
from the trap center. Compared to former measurements without ion optics, the
einzel-lens is focusing down the single-ion beam by a factor of 12. Due to the
small beam divergence and narrow velocity distribution of our ion source,
chromatic and spherical aberration at the einzel-lens is vastly reduced,
presenting a promising starting point for focusing single ions on their way to
a substrate.Comment: 16 pages, 7 figure
Enhanced in vitro antitumor activity of a titanocene complex encapsulated into polycaprolactone (PCL) electrospun fibers.
PURPOSE:
The purpose of this work was to achieve detailed biomaterials characterization of a drug delivery system for local cancer treatment based on electrospun titanocene trichloride-loaded resorbable polycaprolactone (PCL) fibers.
METHODS:
The PCL fibers were characterized for their structural, morphologic and physical properties. The drug release kinetics of the titanocene complex was investigated at different concentrations, to obtain a set of correlations between structure and tuneable release. After exposing cancer cells directly onto the surface of PCL fibers, the anti-proliferative effects of titanocene-loaded PCL were assessed by: (i) counting viable cells via live/dead staining methods, and (ii) analyzing cell apoptosis.
RESULTS AND CONCLUSIONS:
Titanocene concentration influenced fiber diameters reduced for PCL filled with titanocene. X-ray analysis suggested that the titanocene, encapsulated into the PCL fibers, is not allowed to crystallize and exists as amorphous aggregates into the fibers. The titanocene release curves presented two stages unrelated to PCL degradation: an initial burst release followed by a release linear with time, extending for a very long time. All of the titanocene-loaded fibers revealed sustained drug release properties suggesting their potential clinical applicability for the treatment of local cancer diseases
Optimal control of atom transport for quantum gates in optical lattices
By means of optimal control techniques we model and optimize the manipulation
of the external quantum state (center-of-mass motion) of atoms trapped in
adjustable optical potentials. We consider in detail the cases of both non
interacting and interacting atoms moving between neighboring sites in a lattice
of a double-well optical potentials. Such a lattice can perform
interaction-mediated entanglement of atom pairs and can realize two-qubit
quantum gates. The optimized control sequences for the optical potential allow
transport faster and with significantly larger fidelity than is possible with
processes based on adiabatic transport.Comment: revised version: minor changes, 2 references added, published versio
Spin-Dependent Electron Scattering from Polarized Protons and Deuterons with the BLAST Experiment at MIT-Bates
The Bates Large Acceptance Spectrometer Toroid (BLAST) experiment was operated at the MIT-Bates Linear Accelerator Center from 2003 until 2005. The experiment was designed to exploit the power of a polarized electron beam incident on polarized targets of hydrogen and deuterium to measure, in a systematic manner, the neutron, proton, and deuteron form factors as well as other aspects of the electromagnetic interaction on few-nucleon systems. We briefly describe the experiment, and present and discuss the numerous results obtained.United States. Dept. of EnergyNational Science Foundation (U.S.
- âŠ