17 research outputs found

    Néoformations inflammatoires et tumorales dans le sinus maxillaire supérieur d’une brebis

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    Lombard Charles, Cabanié P. Néoformations inflammatoires et tumorales dans le sinus maxillaire supérieur d’une brebis. In: Bulletin de l'Académie Vétérinaire de France tome 119 n°4, 1966. pp. 147-148

    Un cas de mélanose pulmonaire chez le faisan

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    Lombard Charles, Cabanié P. Un cas de mélanose chez le faisan. In: Bulletin de l'Académie Vétérinaire de France tome 119 n°4, 1966. pp. 145-146

    Adénopapillome de la muqueuse pituitaire chez la Chèvre

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    Lombard Charles, Cabanié P., Crespin J. Adénopapillome de la muqueuse pituitaire chez la Chèvre. In: Bulletin de l'Académie Vétérinaire de France tome 119 n°6, 1966. pp. 199-202

    Competitive and stereoselective histamine H1 antagonistic effect of cicletanide in guinea-pig isolated ileum.

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    The histamine H1 antagonistic effects of the racemic form and the enantiomers of cicletanide, a new antihypertensive furopyridine derivative, were investigated in guinea-pig isolated ileum. Both the racemic and the (-) enantiomer behaved as competitive histamine antagonists (pA2 values of 6.8 and 7.2, respectively). The (+) enantiomer was at least 100 times less potent than the (-) enantiomer. The H1-blocking effect of cicletanide is the most potent and is the only stereoselective property so far reported for the drug

    Purification and ligand binding of a soluble class I major histocompatibility complex molecule consisting of the first three domains of H-2Kd fused to beta 2-microglobulin expressed in the baculovirus-insect cell system.

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    A recombinant baculovirus encoding a single-chain murine major histocompatibility complex class I molecule in which the first three domains of H-2Kd are fused to beta 2-microglobulin (beta 2-m) via a 15-amino acid linker has been isolated and used to infect lepidopteran cells. A soluble, 391-amino acid single-chain H-2Kd (SC-Kd) molecule of 48 kDa was synthesized and glycosylated in insect cells and could be purified in the absence of detergents by affinity chromatography using the anti-H-2Kd monoclonal antibody SF1.1.1.1. We tested the ability of SC-Kd to bind antigenic peptides using a direct binding assay based on photoaffinity labeling. The photoreactive derivative was prepared from the H-2Kd-restricted Plasmodium berghei circumsporozoite protein (P.b. CS) peptide 253-260 (YIPSAEKI), a probe that we had previously shown to be unable to bind to the H-2Kd heavy chain in infected cells in the absence of co-expressed beta 2-microglobulin. SC-Kd expressed in insect cells did not require additional mouse beta 2-m to bind the photoprobe, indicating that the covalently attached beta 2-m could substitute for the free molecule. Similarly, binding of the P.b. CS photoaffinity probe to the purified SC-Kd molecule was unaffected by the addition of exogenous beta 2-m. This is in contrast to H-2KdQ10, a soluble H-2Kd molecule in which beta 2-m is noncovalently bound to the soluble heavy chain, whose ability to bind the photoaffinity probe is greatly enhanced in the presence of an excess of exogenous beta 2-m. The binding of the probe to SC-Kd was allele-specific, since labeling was selectively inhibited only by antigenic peptides known to be presented by the H-2Kd molecule

    Isolation of the BVD virus in two cases of haemorrhagic syndrome in charolais Bovine

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    Two cases of haemorrhagic syndrome associated to the infection by non-cytopathogenic strains of Bovine viral diarrhoea virus ( BVDMD ) have been identified in France. The clinical signs are the same in both calves : hyperthermia, haemorrhagic lesions. Further tests are earned out (haematology, histology and virology ). As the prognosis is poor both calves are put to sleep. The BVD virus, of non cyto-pathogenic biotype has been isolated from the blood and organs of affected animals
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