282 research outputs found
Binding Small Molecules to a cis-Dicarbonyl -PNP Complex via Metal–Ligand Cooperativity
Metal–ligand cooperativity is a powerful tool for the activation of various bonds but has rarely, if ever, been studied with the radioactive transition metal Tc. In this work, we explore this bond activation pathway with the dearomatized PNP complex cis-[99TcI(PyrPNPtBu*)(CO)2] (4), which was synthesized by deprotonation of trans-[99TcI(PyrPNPtBu)(CO)2Cl] with KOtBu. Analogous to its rhenium congener, the dearomatized compound reacts with CO2 to form the carboxy complex cis-[99TcI(PyrPNPtBu–COO)(CO)2] and with H2 to form the mono-hydride complex cis-[99TcI(PyrPNPtBu)(CO)2H] (7). Substrates with weakly acidic protons are deprotonated by the Brønsted basic pincer backbone of 4, yielding a variety of intriguing complexes. Reactions with terminal alkynes enable the isolation of acetylide complexes. The deprotonation of an imidazolium salt results in the in situ formation and coordination of a carbene ligand. Furthermore, a study with heterocyclic substrates allowed for the isolation of pyrrolide and pyrazolide complexes, which is uncommon for Tc. The spectroscopic analyses and their solid-state structures are reported
Forward--Backward Asymmetry in B -> X_s l^+ l^- at the NNLL Level
We report the results of a new calculation of soft-gluon corrections in B ->
X_s l^+ l^- decays. In particular, we present the first calculation of
bremsstrahlung and corresponding virtual terms to the lepton forward-backward
asymmetry, which allows us to systematically include all contributions to this
observable beyond the lowest non-trivial order. The new terms are important,
for instance the position of the zero of the asymmetry receives corrections of
O(10%). Using a different method, we also provide an independent check of
recently published results on bremsstrahlung and infrared virtual corrections
to the dilepton-invariant mass distribution.Comment: 20 pages, 5 figures. v2: typo in (4.26) corrected; discussion on
mu-dependence modifie
NNLL QCD Corrections to the Decay
We briefly discuss the status of the NNLL QCD calculations in the inclusive
rare B decay . Two important ingredients, the two-loop
matrix elements of the four quark operator and the bremsstrahlung
contributions, were quite recently finalised. The new contributions
significantly improve the sensitivity of the inclusive decay decay in testing extensions of the standard model in the sector of flavour
dynamics; for instance the two-loop calculation cuts the low- scale uncertainty
in half and the bremsstrahlung calculation leads to a 10% shift of the position
of the zero of the forward- backward asymmetry.Comment: 7 pages, latex, 5 figures, references adde
Soft SUSY Breaking Grand Unification: Leptons vs Quarks on the Flavor Playground
We systematically analyze the correlations between the various leptonic and
hadronic flavor violating processes arising in SUSY Grand Unified Theories.
Using the GUT-symmetric relations between the soft SUSY breaking parameters, we
assess the impact of hadronic and leptonic flavor observables on the SUSY
sources of flavor violation.Comment: 39 pages, 10 figure
Flavor changing Z-decays from scalar interactions at a Giga-Z Linear Collider
The flavor changing decay Z -> d_I \bar{d}_J is investigated with special
emphasis on the b \bar{s} final state. Various models for flavor violation are
considered: two Higgs doublet models (2HDM's), supersymmetry (SUSY) with flavor
violation in the up and down-type squark mass matrices and SUSY with flavor
violation mediated by R-parity-violating interaction. We find that, within the
SUSY scenarios for flavor violation, the branching ratio for the decay Z -> b
\bar{s} can reach 10^{-6} for large \tan\beta values, while the typical size
for this branching ratio in the 2HDM's considered is about two orders of
magnitudes smaller at best. Thus, flavor changing SUSY signatures in radiative
Z decays such as Z -> b \bar{s} may be accessible to future ``Z factories''
such as a Giga-Z version of the TESLA design.Comment: 27 pages, 15 figures, REVTeX4. A new section added and a few minor
corrections were made in the tex
B decays and Supersymmetry
I discuss how supersymmetry affects various observables in B decays, and
point out the interesting channels in the context of B factories.Comment: LaTex file of working group talk presented at WHEPP-7, HRI,
Allahabad, Jan. 200
Calculation of two-loop virtual corrections to b --> s l+ l- in the standard model
We present in detail the calculation of the virtual O(alpha_s) corrections to
the inclusive semi-leptonic rare decay b --> s l+ l-. We also include those
O(alpha_s) bremsstrahlung contributions which cancel the infrared and mass
singularities showing up in the virtual corrections. In order to avoid large
resonant contributions, we restrict the invariant mass squared s of the lepton
pair to the range 0.05 < s/mb^2 < 0.25. The analytic results are represented as
expansions in the small parameters s/mb^2, z = mc^2/mb^2 and s/(4 mc^2). The
new contributions drastically reduce the renormalization scale dependence of
the decay spectrum. For the corresponding branching ratio (restricted to the
above s-range) the renormalization scale uncertainty gets reduced from +/-13%
to +/-6.5%.Comment: 41 pages including 9 postscript figures; in version 2 some typos and
inconsistent notation correcte
Functional features of gene expression profiles differentiating gastrointestinal stromal tumours according to KIT mutations and expression
<p>Abstract</p> <p>Background</p> <p>Gastrointestinal stromal tumours (GISTs) represent a heterogeneous group of tumours of mesenchymal origin characterized by gain-of-function mutations in <it>KIT </it>or <it>PDGFRA </it>of the type III receptor tyrosine kinase family. Although mutations in either receptor are thought to drive an early oncogenic event through similar pathways, two previous studies reported the mutation-specific gene expression profiles. However, their further conclusions were rather discordant. To clarify the molecular characteristics of differentially expressed genes according to GIST receptor mutations, we combined microarray-based analysis with detailed functional annotations.</p> <p>Methods</p> <p>Total RNA was isolated from 29 frozen gastric GISTs and processed for hybridization on GENECHIP<sup>® </sup>HG-U133 Plus 2.0 microarrays (Affymetrix). <it>KIT </it>and <it>PDGFRA </it>were analyzed by sequencing, while related mRNA levels were analyzed by quantitative RT-PCR.</p> <p>Results</p> <p>Fifteen and eleven tumours possessed mutations in <it>KIT </it>and <it>PDGFRA</it>, respectively; no mutation was found in three tumours. Gene expression analysis identified no discriminative profiles associated with clinical or pathological parameters, even though expression of hundreds of genes differentiated tumour receptor mutation and expression status. Functional features of genes differentially expressed between the two groups of GISTs suggested alterations in angiogenesis and G-protein-related and calcium signalling.</p> <p>Conclusion</p> <p>Our study has identified novel molecular elements likely to be involved in receptor-dependent GIST development and allowed confirmation of previously published results. These elements may be potential therapeutic targets and novel markers of <it>KIT </it>mutation status.</p
Stau LSP and comparison with H^+(-) phenomenology
In supersymmetric models with explicit breaking of R-parity the lightest
supersymmetric particle (LSP) may be the lightest stau, \stau_1. Such a
scenario would provide a clear sign of R-parity violating SUSY, although its
phenomenology may resemble that of a charged Higgs boson, . We discuss
various ways of distinguishing a LSP \stau_1 from at future
colliders, and address the case of \stau_1 mimicking the signal for .
As an example we suggest that the recent L3 signal for and
could be more easily explained by a LSP
\stau_1.Comment: 22 pages, 2 figures, Revtex, short discussion and references adde
b -> s gamma in the left-right supersymmetric model
The rare decay is studied in the left-right supersymmetric
model. We give explicit expressions for all the amplitudes associated with the
supersymmetric contributions coming from gluinos, charginos and neutralinos in
the model to one-loop level. The branching ratio is enhanced significantly
compared to the standard model and minimal supersymmetric standard model values
by contributions from the right-handed gaugino and squark sector. We give
numerical results coming from the leading order contributions. If the only
source of flavor violation comes from the CKM matrix, we constrain the scalar
fermion-gaugino sector. If intergenerational mixings are allowed in the squark
mass matrix, we constrain such supersymmetric sources of flavor violation. The
decay sets constraints on the parameters of the model and
provides distinguishing signs from other supersymmetric scenarios.Comment: 12 figure
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