Chondromyxoid Fibroma of Sphenoid Sinus with Unusual Calcifications: Case Report with Literature Review

Chondromyxoid fibroma (CMF) is a rare benign primary tumor which usually affects the metaphyses of the long bone of the lower extremities in childhood and young adults. Rarely, CMF occurs in the skull base and parasinuses, which may be difficult to distinguish from chondrosarcoma or chordoma and other tumors in the head. It is composed of chondroid, myxoid, and fibrous tissue growth in a lobular pattern, infrequently with calcifications. We report one case of CMF involving the sphenoid sinus mimicking a chondrosarcoma. The tumor mass showed calcifications on images and histology

Prediction of abnormalities in heart beat sounds using convolutional neural networks

Worldwide physicians prefer to use physical stethoscope and they listen to the heart beat sound and its rhythm to diagnose various heart conditions.  In this work various abnormalities that happened in heart will be reflected in the sound of the heartbeat. In this work we have created a classification system which is based on Convolutional Neural Network (CNN) to analyze the heart beat sound to predict the abnormalities. Heart beat sound is converted to spectrogram images and then CNN is trained with those images. In order to reduce the computational time, pooling is done, so that it reduces the parameters by taking particular pixel from particular part of pixels. The parameters in CNN are varied in the convolution and pooling layers to enhance the accuracy of classification of heart beat sound. Experiment is carried out by varying number of convolutional layers and by changing the pooling methods for various combinations of CNN models and the results are analyzed to find the optimal combination which can suit for sound analysis

Effect of rosiglitazone on the frequency of diabetes in patients with impaired glucose tolerance or impaired fasting glucose: a randomised controlled trial

Background Rosiglitazone is a thiazolidinedione that reduces insulin resistance and might preserve insulin secretion. The aim of this study was to assess prospectively the drugs ability to prevent type 2 diabetes in individuals at high risk of developing the condition