Hubungan Antara Kualifikasi Akademik, Kompetensi, Motivasi Kerja Dengan Kinerja Guru Sekolah Dasar (SD) Di Kecamatan Bajawa, Kabupaten Ngada

Penelitian ini bertujuan untuk mengetahui hubungan antara kualifikasi akademik, kompetensi, motivasi kerja dengan kinerja guru sekolah dasar (SD) di kecamatan Bajawa, kabupaten Ngada. Populasi penelitian ini adalah seluruh guru sekolah dasar di Kecamatan Bajawa, Kabupaten Ngada yang berjumlah 366 orang. Sesuai dengan tabel Krejcie dan Morgan serta formula Wenwich banyaknya anggota sampel adalah 188 orang.Pengambilan sampel dilakukan dengan teknik random sampling. Penelitian ini menggunakan rancangan ex-post facto dengan teknik korelasioanl. Data yang dikumpulkan dalam penelitian ini menggunakan kuesioner dengan mengikuti pola Likert. Untuk menguji hipotesis pertama, kedua dan ketiga (H 1,2,3) di gunakan teknik analisis regresi sederhana, sedangkan untuk menguji hipotesis keempat (H4) digunakan analisis regresi berganda dan uji-F. Hasil penelitian menunjukkan bahwa; 1) terdapat hubungan yang positif dan signifikan antara kualifikasi akademik dengan kinerja guru,2) terdapat hubungan yang positif dan signifikan antara kompetensi dengan kinerja guru, 3) terdapat hubungan yang positif dan signifikan antara motivasi kerja dengan kinerja guru, 4) terdapat hubungan yang positif dan signifikan secara bersama – sama antara kualifikasi akademik, kompetensi, motivasi kerja dengan kinerja guru. Dengan demikian ke tiga faktor kualifikasi akademik, kompetensi dan motivasi kerja dapat dijadikan prediktor tingkat kecenderungan kinerja guru sekolah dasar di kecamatan Bajawa, kabupaten NgadaKata Kunci : Kinerja Guru, Kompetensi, Kualifikasi Akademik, Motivasi Kerja. This research intends to know the relation Academic Qualification, Competence,Work Motivation with teascher performance in Bajawa District,Ngada Regency .This Reseacrh Population is from all Elementary School Teacher in Bajawa District,Ngada Regency which has 336 person. Accordance with Krejcie and Morgan tabel with Wenwich formulation , the amount of sample member was taken from 188 persons. The way for using sample was done with random sample tecnic. This research us ed expost facto design with corelation technice. The collected data in this research used quetionnaire by following the Likert model. For testing First,second and third hypotesis (H1,2,3) was used with simple regression technic, while for testing the fourth hypothesis (H4) was used multiple regression analysis and F-test. This Research shows that (1) found the positive and significant relation between Academic Qualification with the Teacher Performance,(2) found the positive and significant relation between teacher competence with teacher performance, 3) found the positive and significant relation between work motivation with teacher performance , (4) found the positive and significant relation together between Academic Qualification, Competence, Work Motivation with the Teacher Performance. Thus, this three factor can be become a predictor to tendency level of Elementary School Teacher Perfomance in Bajawa District, Ngada Regenc

Effect of stirring and ultrasound assisted extraction conditions in flavonoids, tannins, antioxidant and antimicrobial activities of chestnut outer shells (Castanea sativa Miller)

Portugal is one of the main producersof chestnut in Europe.info:eu-repo/semantics/publishedVersio

Gellan gum-based hydrogels support the recreation of the dermal papilla microenvironment

The dermal papilla (DP), a specialized compartment within the hair follicle, regulates hair growth. However, human DP cells rapidly lose their inductivity in 2D-culture given the loss of positional and microenvironmental cues. Spheroids have been capable of recreating the 3D intercellular organization of DP cells, however, DP cell-matrix interactions are poorly represented. Considering the specific nature of the DP's extracellular matrix (ECM), we functionalized gellan gum (GG) with collagen IV-(HepIII) or fibronectin-(cRGDfC) derived peptide sequences to generate a 3D environment in which the phenotype and physiological functions of DP cells are restored. We further tuned the stiffness of the microenvironments by varying GG amount. Biomimetic peptides in stiffer hydrogels promoted the adhesion of DP cells, while each peptide and amount of polymer independently influenced the type and quantity of ECM proteins deposited. Furthermore, although peptides did not seem to have an influence, stiffer hydrogels improved the inductive capacity of DP cells after short term culture. Interestingly, independently of the peptide, these hydrogels supported the recapitulation of basic hair morphogenesis-like events when incorporated in an organotypic human skin in vitro model. Our work demonstrates that tailored GG hydrogels support the generation of a microenvironment in which both cell-ECM and cell-cell interactions positively influence DP cells towards the creation of an artificial DP.Authors would like to acknowledge the financial support from the Consolidator Grant “ECM_INK” (ERC-2016-COG-726061) and from FCT/MCTES (Fundação para a Ciência e a Tecnologia/Ministério da Ciência, Tecnologia e Ensino Superior) through the PD/59/2013, PD/BD/113800/2015 (Carla Abreu), PD/169/2013 (Manuela Lago) and IF/00945/2014 (Alexandra Marques) grants. The authors also appreciate the support given by the FSE/POCH (Fundo Social Europeu through the Programa Operacional do Capital Humano) under the scope of the NORTE-08-5369-FSE-000037 grant (Manuela Lago)

Exploring perceived barriers to physical activity among older adults living in low-population density regions: gender differences and associations with activity dimensions

Older people in low-population density regions tend to have fewer resources to engage in regular physical activity (PA) compared to their counterparts in urban areas. Moreover, PA assumes different dimensions, and the amount of PA related to each dimension may differ between women and men, predisposing them to different PA practices. Therefore, this cross-sectional study aims to describe the prevalence of barriers to PA, gender differences, and their associations with different PA dimensions. A total of 259 older adults (153 women and 106 men; age, 75.17 8.05 years old) living in the community in the region of Guarda (Portugal) were interviewed face to face to record their sociodemographic characteristics, general health status (comorbidity index and self-reported health), PA behaviour, and barriers to PA.Women were more likely to report “low” income and living alone (p 0.05), while men reported a higher negative health status than women (p < 0.05). Two intrinsic (“Fear of injury” (40.1%) and “Need for rest” (26.3%)) and two extrinsic barriers (“Lack of nearby facilities” (30.5%) and “I don’t have transport” (25.6%)) were the most prevalent. For women, age, self-reported health, comorbidity index, and intrinsic and extrinsic barriers were similarly associated with the different PA dimensions. However, only self-reported health and extrinsic barriers were the variables associated with the different PA dimensions in men. Therefore, strategies to promote active ageing in low-population density regions should be focused on reducing intrinsic and extrinsic barriers based on gender and the PA dimension to be achieved.This study was funded by PORTUGAL2020 and by the Fundação para a Ciência e a Tecnologia (FCT, I.P.), under project SAICT-POL/23811/2016 and through the Portuguese Foundation for Science and Technology, I.P., under project UIDB/04045/2020. The Polytechnic of Guarda partly supported the research reported in this publication.info:eu-repo/semantics/publishedVersio

Diagnosing Severe Falciparum Malaria in Parasitaemic African Children: A Prospective Evaluation of Plasma PfHRP2 Measurement.

In African children, distinguishing severe falciparum malaria from other severe febrile illnesses with coincidental Plasmodium falciparum parasitaemia is a major challenge. P. falciparum histidine-rich protein 2 (PfHRP2) is released by mature sequestered parasites and can be used to estimate the total parasite burden. We investigated the prognostic significance of plasma PfHRP2 and used it to estimate the malaria-attributable fraction in African children diagnosed with severe malaria. Admission plasma PfHRP2 was measured prospectively in African children (from Mozambique, The Gambia, Kenya, Tanzania, Uganda, Rwanda, and the Democratic Republic of the Congo) aged 1 month to 15 years with severe febrile illness and a positive P. falciparum lactate dehydrogenase (pLDH)-based rapid test in a clinical trial comparing parenteral artesunate versus quinine (the AQUAMAT trial, ISRCTN 50258054). In 3,826 severely ill children, Plasmadium falciparum PfHRP2 was higher in patients with coma (p = 0.0209), acidosis (p<0.0001), and severe anaemia (p<0.0001). Admission geometric mean (95%CI) plasma PfHRP2 was 1,611 (1,350-1,922) ng/mL in fatal cases (n = 381) versus 1,046 (991-1,104) ng/mL in survivors (n = 3,445, p<0.0001), without differences in parasitaemia as assessed by microscopy. There was a U-shaped association between log(10) plasma PfHRP2 and risk of death. Mortality increased 20% per log(10) increase in PfHRP2 above 174 ng/mL (adjusted odds ratio [AOR] 1.21, 95%CI 1.05-1.39, p = 0.009). A mechanistic model assuming a PfHRP2-independent risk of death in non-malaria illness closely fitted the observed data and showed malaria-attributable mortality less than 50% with plasma PfHRP2≤174 ng/mL. The odds ratio (OR) for death in artesunate versus quinine-treated patients was 0.61 (95%CI 0.44-0.83, p = 0.0018) in the highest PfHRP2 tertile, whereas there was no difference in the lowest tertile (OR 1.05; 95%CI 0.69-1.61; p = 0.82). A limitation of the study is that some conclusions are drawn from a mechanistic model, which is inherently dependent on certain assumptions. However, a sensitivity analysis of the model indicated that the results were robust to a plausible range of parameter estimates. Further studies are needed to validate our findings. Plasma PfHRP2 has prognostic significance in African children with severe falciparum malaria and provides a tool to stratify the risk of "true" severe malaria-attributable disease as opposed to other severe illnesses in parasitaemic African children

Detectores de radiação em Portugal no século XX

info:eu-repo/semantics/publishedVersio

Genetic heterogeneity in Italian families with IgA nephropathy: suggestive linkage for two novel IgA nephropathy loci.

IgA nephropathy (IgAN) is the most common glomerulonephritis worldwide, but its etiologic mechanisms are still poorly understood. Different prevalences among ethnic groups and familial aggregation, together with an increased familial risk, suggest important genetic influences on its pathogenesis. A locus for familial IgAN, called "IGAN1," on chromosome 6q22-23 has been described, without the identification of any responsible gene. The partners of the European IgAN Consortium organized a second genomewide scan in 22 new informative Italian multiplex families. A total of 186 subjects (59 affected and 127 unaffected) were genotyped and were included in a two-stage genomewide linkage analysis. The regions 4q26-31 and 17q12-22 exhibited the strongest evidence of linkage by nonparametric analysis (best P=.0025 and .0045, respectively). These localizations were also supported by multipoint parametric analysis, in which peak LOD scores of 1.83 ( alpha =0.50) and 2.56 ( alpha =0.65) were obtained using the affected-only dominant model, and by allowance for the presence of genetic heterogeneity. Our results provide further evidence for genetic heterogeneity among families with IgAN. Evidence of linkage to multiple chromosomal regions is consistent with both an oligo/polygenic and a multiple-susceptibility-gene model for familial IgAN, with small or moderate effects in determining the pathological phenotype. Although we identified new candidate regions, replication studies are required to confirm the genetic contribution to familial IgA

Generation of Gellan Gum-Based Adipose-Like Microtissues

Adipose tissue is involved in many physiological processes. Therefore, the need for adipose tissue-like analogues either for soft tissue reconstruction or as in vitro testing platforms is undeniable. In this work, we explored the natural features of gellan gum (GG) to recreate injectable stable adipose-like microtissues. GG hydrogel particles with different percentages of polymer (0.5%, 0.75%, 1.25%) were developed and the effect of obtained mechanical properties over the ability of hASCs to differentiate towards the adipogenic lineage was evaluated based on the expression of the early (PPARγ) and late (FABP4) adipogenic markers, and on lipids formation and accumulation. Constructs were cultured in adipogenic induction medium up to 21 days or for six days in induction plus nine days in maintenance media. Overall, no significant differences were observed in terms of hASCs adipogenic differentiation within the range of Young’s moduli between 2.7 and 12.9 kPa. The long-term (up to six weeks) stability of the developed constructs supported its application in soft tissue reconstruction. Moreover, their ability to function as adipose-like microtissue models for drug screening was demonstrated by confirming its sensitivity to TNFα and ROCK inhibitor, respectively involved in the repression and induction of the adipogenic differentiation.FSE/POCH-PD/169/2013, NORTE-08-5369-FSE-000037 (MELL), POCI-01-0145-FEDER-007038—UMINHO/BPD/44/2016 (LdS); Portuguese Foundation for Science and Technology (FCT) for grant SFRH/BPD/109595/2015 (AFC); IF/00945/2014 (APM); The Discoveries Centre for Regenerative and Precision Medicine (H2020-WIDESPREAD-2014-1-739572)info:eu-repo/semantics/publishedVersio

ONTOLOGIA E MEDIAÇÃO: KANT, PEIRCE E JUNG

The origins of this text are a result from the reflections accomplished in group, during the development of the disciplines &ldquo;Epistemology and Science&rdquo; and &ldquo;Semiotics, Aesthetics and Knowledge&rdquo;, both of the Post-Graduate Program in Knowledge Engineering and Management - UFSC. The main approached subject is the intuition in the knowledge origin, as it was proposed firstly in the categories presented in the &quot;Critical of Pure Reason&quot; of Immanuel Kant, which had questioned the cartesianism. Later, the Kantian categories were also criticized by Charles S. Peirce, that was author of a series of seven questions on the theme in study. Those questions are presented and discussed to follow, in accordance with the Peirce&rsquo;s thought and, also, with Carl Gustav Jung ideas. The convergence point that justifies the confrontation of the Peirce and Jung ideas is the symbol concept that was adopted and particularly developed by the two thinkers.As origens deste texto decorrem das reflex&otilde;es realizadas em grupo, durante o desenvolvimento das disciplinas &ldquo;Epistemologia e Ci&ecirc;ncia&rdquo; e &ldquo;Semi&oacute;tica, Est&eacute;tica e Conhecimento&rdquo;, ambas do Programa de P&oacute;s-Gradua&ccedil;&atilde;o em Engenharia e Gest&atilde;o do Conhecimento - UFSC. A principal quest&atilde;o abordada &eacute; a intui&ccedil;&atilde;o na origem do conhecimento, como foi primeiramente proposta nas categorias apresentadas na &ldquo;Cr&iacute;tica da Raz&atilde;o Pura&rdquo; de Immanuel Kant, as quais questionaram o cartesianismo. Posteriormente, as categorias kantianas tamb&eacute;m foram criticadas por Charles S. Peirce, que foi autor de uma s&eacute;rie de sete quest&otilde;es sobre o tema em estudo. Essas quest&otilde;es s&atilde;o apresentadas e discutidas a seguir, de acordo com o pensamento de Peirce e, tamb&eacute;m, com as id&eacute;ias de Carl Gustav Jung. O ponto de converg&ecirc;ncia que justifica o confronto das id&eacute;ias de Peirce e Jung &eacute; o conceito de s&iacute;mbolo que foi adotado e particularmente desenvolvido pelos dois pensadores