81 research outputs found

    Ranking Of Sustainability Criteria For Industrial Symbiosis Applications Based On Anp

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    ALAKAS, Haci Mehmet/0000-0002-9874-7588WOS:000599463700004Enterprises have started to establish partnerships both to use their internal resources efficiently and to increase their environmental performance. Partnerships and interoperability of enterprises with different processes enable them to benefit more from their benefits. Moving towards the local and regional economy, these partnerships that increase environmental and own resources have created industrial symbiosis practices. Industrial ecology fields are established in these applications. Both environmental and economic gains can be achieved through the efficient use of resources by enterprises and the minimization of wastes. For the sustainability of these partnerships to be established by enterprises, they need to analyze the measures they take internally. In this study, the concept of industrial symbiosis and the criteria that are effective for the sustainability of these industrial symbiosis are evaluated. Analytical network process method is used. Thus, the industrial symbiosis infrastructures to be established by enterprises have been enabled to move strategically

    Askin's Tumor in an Adult: Case Report and Findings on 18F-FDG PET/CT

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    Primitive neuroectodermal tumor (PNET) of the chest wall or Askin's tumor is a rare neoplasm of chest wall. It most often affects children and adolescents and is a very rare tumor in adults. In this case report, we present an Askin's tumor occurred in a 73-year-old male. The patient was admitted with a history of 3-month lower back pain and cough. In computed tomography, there was a lesion with dimensions of 70 × 40 × 65 mm in the superior segment of the lower lobe of the left lung. Positron emission tomography/computed tomography with 18F-flourodeoxyglucose revealed a pleural-based tumor in the left lung with a maximum standardized uptake value of 4.36. No distant or lymph node metastases were present. The patient had gone through surgery, and wedge resection of the superior segment of left lobe and partial resection of the ipsilateral ribs were performed. Pathology report with immunocytochemistry was consistent with PNET and the patient received chemotherapy after that

    Pegylation of poly(γ-benzyl-L-glutamate) nanoparticles is efficient for avoiding mononuclear phagocyte system capture in rats

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    Poly(γ-benzyl-L-glutamate) (PBLG) derivatives are synthetic polypeptides for preparing nanoparticles with well controlled surface properties. The aim of this paper was to investigate the biodistribution of pegylated PBLG in rats. For this purpose, nanoparticles were prepared by a nanoprecipitation method using mixtures of different PBLG derivates, including a pegylated derivate to avoid mononuclear phagocyte system uptake. The morphology, size distribution, and surface charge of the nanoparticles were investigated as a function of the amount of polymer employed for the preparation. Moderately polydispersed nanoparticles (polydispersity index less than 0.2) were obtained. Their size increased with polymer concentration. The zeta potential values were negative whatever the formulations. The availability of polyethylene glycol chains on the nanoparticles’ surface was confirmed by measuring the decrease in bovine serum albumin adsorption. For in vivo distribution studies, pegylated and nonpegylated nanoparticles were prepared with polymer mixtures containing PBLG-fluorescein isothiocyanate and imaged by fluorescence microscopy to measure their accumulation in liver and spleen tissues of rats after intravenous administration. Injection of stealth formulations resulted in negligible fluorescence in liver and spleen compared with nonpegylated formulations, which suggests that these nanoparticles are promising candidates as a stealth-type long-circulating drug carrier system and could be useful for active targeting of drugs while reducing systemic side effects

    Patterns of lipid biomarkers in the fruit of Bupleurum L. growing wild in Turkey

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    Four Bupleurum species, representing two sections, were collected from their natural habitats and the fatty acid and sterol compositions and alpha-tocopherol contents of their fruit oils examined. The major fatty acids were oleic, linoleic and palmitic acids in all species (41.13-79.92%, 11.07-23.21% and 3.52-7.60%, respectively). Delta-5-Avenasterol, stigmasterol, beta-sitosterol, Delta-5,24-stigmastadienol and campesterol exhibited in significant concentrations in all species (9.63-48.79%, 15.42-33.44%, 16.11-25.35%, 12.67-22.97% and 3.10-4.86%, respectively). Higher a-tocopherol concentrations were quantified in both species from section Eubupleura (2.55-2.70 mg/100 g) than in section Perfoliata. Significant correlations were found among the fatty acid and phytosterol quantities observed in the Bupleurum accessions. The results indicated that these species have potential as alternative raw materials and nutraceutical sources through the selection of high yield cultivars and agricultural production

    Accumulation patterns of some seed oil components from wild sources of Turkey

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    Accumulation profiles of fatty acids and a-tocopherol were analysed at three ripening stages in the seed oils of Primula and Echium species. Total seed oils were increased considerably with maturation, while a-tocopherol contents decreased in both species. Increased levels of ALA and oleic acid, and decrease in linoleic and palmitic acids at late ripening stages of Primula sibthorpii, and slightly fluctuations of all examined fatty acids in Echium italicum were observed. Considerable amounts of a-tocopherol (27.4?mg/100?g), linoleic acid (42.76%) and ALA (25.46%) and GLA (4.11%) were detected in Ribes alpinum. Typical accumulation patterns of the examined parameters may be useful for species characterisation and biochemical monitoring of seed development in natural conditions

    Differentiation of Symphytum Species Using RAPD and Seed Fatty Acid Patterns

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    RAPD and fatty acid profiles, and alpha-tocoferol contents of the seeds of some Symphytum species were analyzed for their differentiation. Discriminative patterns were found in the examined species. Genotypic characteristics of three Symphytum species were experienced using 20 decamer RAPD primers. The majority of band positions varied between species. The total amplified products of 20 RAPD primers was 247 (average of 12.35 bands per primer), of which 189 bands were polymorphic, corresponding to nearly 76.1% genetic diversity. The number of bands for each RAPD primer varied from 8 (UBC320) to 18 (OPA7). The percent of polymorphic bands ranged from 45.4% (OPJ20) to 93.3% (OPA16). Major unsaturated fatty acids in the seeds were linoleic, gamma-linolenic and oleic acids; alpha-linolenic and eicosenoic acids exhibited lower levels. Variations in quantities and total ratios of fatty acid groups, and alpha-tocopherol contents were also observed between the species, and the developmental stages of the seeds. Significant differences were found for the whole series of fatty acids between species, in addition to the calculated ratios (p < 0.05). Differences were also significant for fatty acid traits between two developmental stages of the seeds of endemic S. pseudobulbosum (p < 0.05). In some morphological descriptors of the seeds, difference was found at a significant level (p < 0.05). Obtained data based on genetic and biochemical variations seem to be useful for molecular delimitation of Symphytum, in addition to selection of the genotypes expressing a high amount of GLA

    SEM observations on. petals and fruits of some Turkish endemic Bupleurum L. (Umbelliferae) species

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    Petal and fruit surface sculpturing are reported for seven endemic Bupleurum species in Turkey. Considerable differences in the dorsal surface of petals were observed, but major structural similarities were found in the ventral surface of petals. Significant taxonomic differences between species were determined on the surfaces of the fruits. These microstructural surface features are evaluated as possible consistent parameters in the delimitation of species of Bupleurum. (C) 2002 The Linnean Society of London, Botanical Journal of the Linnean Society, 2002, 138, 441-449

    Analysis of the fruit surfaces in Bupleurum L. (Umbelliferae) with SEM

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    20 Bupleurum L. taxa were investigated for micromorphological typology of the fruit surfaces with SEM. Considerably different types of sculpturing at species and subspecies level and similarities between related taxa were observed. A dichotomic key was prepared using the diagnostic surface patterns. Reticulate (sect. Bupleurum), rugose (sect. Aristata Godron subsect. Aristata) and rugulose-colliculate-verrucate (subsect. Juncea Briq.) types of surface structures were distinguished. Micromorphological characteristics may be valuable additional taxonomical criteria for the delimitation of infrageneric groups of species

    Analysis of the total oil and fatty acid composition of seeds of some Boraginaceae taxa from Turkey

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    Mature seed samples of twenty-four Boraginaceae taxa collected from their natural habitats in Turkey were analysed by GC for total oil content and fatty acid composition. The range of total fat in the taxa varied between 7.0 and 35.7%. The amounts of palmitic (16:0) and stearic (18:0) acids determined were 5.65-17.81 and 1.49-5.08%, respectively. Mono-unsaturated fatty acids were in the range 8.83-55.32% for oleic, 0.22-6.21% for eicosenoic, 0.04-8.94% for erucic, and 0.08-2.71% for nervonic acid. Poly-unsaturated fatty acids were between 1.41 and 68.44% for linoleic, 0.12 and 43.0% for alpha-linolenic, 0.04 and 24.03% for gamma-linolenic, and 0.02 and 14.59% for stearidonic acid. Total saturated (9.3-23.7%), mono-unsaturated (10.59-73.28%), and poly-unsaturated fatty acids (13.91-68.78%) varied substantially. Total unsaturated fatty acids ranged from 70.12 to 90.29%. There were significant differences between fatty acid profiles at taxa (P < 0.05) at genera levels, based on mono-unsaturated and poly-unsaturated fatty acid concentrations (P < 0.05). Segregation at the generic level by principle-component analysis was accomplished based on nine major fatty acids. The fatty acid patterns, their relative proportions, and quantities of unusual fatty acids as additional biochemical markers seem to be useful in the taxonomy of Boraginaceae at generic and infrageneric levels. All taxa are, in general, rich in linoleic and alpha-linolenic acids as essential fatty acids for dietary reference intakes. Seed oils of Symphytum, Anchusa, and Trachystemon orientalis for gamma-linolenic acid and Echium for both gamma-linolenic and stearidonic acid may be evaluated as alternative wild sources

    Molecular (RAPDs and Fatty acid) and micromorphological variations of Echium italicum L. populations from Turkey

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    Populational variations of Echium italicum were analysed based on RAPD, fatty acid and micromorphological patterns of the nutlets. Some minor differences in nutlet morphology and the surface sculpturing were detected. Total oil concentrations ranged from 19.3 [A2(E)] to 23.5 % (A1) among the populations. Significant variations between accessions were detected for fatty acid concentrations. Major unsaturated fatty acids were alpha-linolenic, linoleic, oleic, stearidonic and gamma-linolenic acids respectively. The highest values for stearidonic (15.48 %) and gamma-linolenic acid (7.66 %) were obtained from A2(E) population. The total amplified products of 15 RAPD primers was 220 (average of 14.6 bands per primer), of which 156 bands were polymorphic, corresponding to nearly 70.9 % genetic diversity. The number of bands for each RAPD primer varied from 7 (OPD14) to 30 (OPC6). Percent of polymorphic bands ranged from 0.7 % (OPC19) to 100 % (OPC4 and OPD19). Examined traits showing high polymorphism seems to be useful for the taxonomical circumscription, infraspecific delineations and segregation of the populations of E. italicum. Based on the dendrograms of RAPD and fatty acid data, investigated accessions may be separated into subgroups A1, C2, and Irano-Turanian and Mediterranean. Obtained results may be also evaluated for characterization of E. italicum germplasm in selection of high yield genotypes for the production of long chain omega-3 PUFAs including SDA and GLA, and improvement of oil crops in the field
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