Cruzamento natural e distância de isolamento entre genótipos de algodão na turquia

The purposes of this study were to determine the percentage of out-crossing, isolation distance and pollinator insect species for cotton (Gossypium hirsutum L.) seed production in the Aydin region in Turkey. The glandless and red-leaf traits in G. hirsutum were used as genetic markers. Two experiments were conducted over two years that monitored out-crossing in adjacent rows and adjacent plants and established that the percentage of out-crossing varied. The percentage of out-crossing varied between 0% and 13.3% depending on the genetic marker. In the experiment to determine isolation distance, natural crossing percentage was not observed in 2002, while this percentage was 0.8% in the first rows in 2003. In this study, cotton fields were also visited once a week during flowering periods for seven weeks in order to determine the numbers of pollinator insect species, where the only detected species was the honey bee. The numbers of pollinator insects were 2.14% (2002) and 1.30% (2003) for adjacent rows; 1.71% (2002) and 2.00% (2003) for adjacent plants in glandless parcels. It is recommended that the isolation distance between genotypes should be approximately 1 m.Os objetivos deste estudo foram determinar a percentagem de cruzamentos livres, a distância de isolamento e as espécies de insetos polinizadores na produção de sementes de algodão (Gossypium hirsutum L.) na região de Aydin, na Turquia. Foram utilizadas as características ausência de glândulas e folhas vermelhas como marcadores de G. hirsutum. Dois experimentos foram conduzidos durante dois anos, nos quais os cruzamentos livres em linhas e plantas adjacentes foram monitorados, tendo sido comprovada uma variação na percentagem de cruzamentos livres que variou entre 0 e 13,3% dependendo do marcador genético. No experimento de determinação da distância de isolamento, não se observou cruzamento natural em 2002, mas em 2003 sua percentagem foi de 0,8%, apenas nas primeiras linhas. Neste estudo, os campos de algodão foram visitados uma vez por semana, por sete semanas, para determinar o número de espécies de insetos polinizadores, tendo sido encontradas abelhas produtoras de mel. O número encontrado foi de 2,14% (2002) e 1,30% (2003) para linhas adjacentes; 1,71% (2002) e 2,00% (2003) para plantas em parcelas com ausência de glândulas. É recomendado que a distância de isolamento entre genótipos deva ser de aproximadamente 1 m

Minimal residual disease (MRD) detection with translocations and T-cell receptor and immunoglobulin gene rearrangements in adult acute lymphoblastic leukemia patients: a pilot study

Objective: Monitoring minimal residual disease has become increasingly important in clinical practice of ALL management. Break-point fusion regions of leukaemia related chromosomal aberrations and rearranged immunoglobulin (Ig) and T cell-receptor (TCR) genes are used as leukaemia specific markers in genetic studies of MRD.Material and Methods: A total of 31 consecutive patients with newly diagnosed ALL were screened for eligibility criteria. Of those 26 were included in the study. One patient with partial response following induction therapy and four patients who were lost to follow-up after induction were excluded from the study; thus 21 patients were evaluated for MRD by using polymerase chain reaction (PCR), heteroduplex analysis, sequencing and quantitative real time PCR techniques. Results: Chromosomal aberrations were detected in 5 (24%) of the patients and were used for MRD monitoring. Three patients had t(9;22) translocation, the other 2 had t(4;11) and t(1;19). MRD-based risk stratification of the16 patients analysed for Ig/TCR rearrangements revealed 3 low-risk, 11 intermediate-risk and 2 high-risk patients.Conclusion: MRD monitoring is progressively getting to be a more important predictive factor in adult ALL patients. As reported by others confirmed by our limited data there is a good correlation between MRD status and clinical outcome in patients receiving chemotherapy. The pilot-study presented here is the first that systematically and consecutively performs a molecular MRD monitoring of ALL patients in Turkey

Trends in distance education research: A content analysis of journals 2009-2013

This study intends to explore the current trends in the field of distance education research during the period of 2009-2013. The trends were identified by an extensive review of seven peer reviewed scholarly journals: The American Journal of Distance Education (AJDE), Distance Education (DE), The European Journal of Open, Distance and e-Learning (EURODL), The Journal of Distance Education (JDE), The Journal of Online Learning and Technology (JOLT), Open Learning: The Journal of Open, Distance and e-Learning (OL) and The International Review of Research in Open and Distributed Learning (IRRODL). A total of 861 research articles was reviewed. Mainly content analysis was employed to be able to analyze the current research. Also, a social network analysis (SNA) was used to interpret the interrelationship between keywords indicated in these articles. Themes were developed and the content of the articles in the selected journals were coded according to categories derived from earlier studies. The results were interpreted using descriptive analysis (frequencies) and social network analysis. The reporting of the results were organized into the following categories: research areas, theoretical and conceptual frameworks, variables, methods, models, strategies, data collection and analysis methods, and the participants. The study also identified the most commonly used keywords, and the most frequently cited authors and studies in distance education. The findings obtained in this study may be useful in the exploration of potential research areas and identification of neglected areas in the field of distance education

Volume CXIV, Number 4, November 7, 1996

Objective: Turner syndrome (TS) is a chromosomal disorder caused by complete or partial X chromosome monosomy that manifests various clinical features depending on the karyotype and on the genetic background of affected girls. This study aimed to systematically investigate the key clinical features of TS in relationship to karyotype in a large pediatric Turkish patient population.Methods: Our retrospective study included 842 karyotype-proven TS patients aged 0-18 years who were evaluated in 35 different centers in Turkey in the years 2013-2014.Results: The most common karyotype was 45,X (50.7%), followed by 45,X/46,XX (10.8%), 46,X,i(Xq) (10.1%) and 45,X/46,X,i(Xq) (9.5%). Mean age at diagnosis was 10.2±4.4 years. The most common presenting complaints were short stature and delayed puberty. Among patients diagnosed before age one year, the ratio of karyotype 45,X was significantly higher than that of other karyotype groups. Cardiac defects (bicuspid aortic valve, coarctation of the aorta and aortic stenosis) were the most common congenital anomalies, occurring in 25% of the TS cases. This was followed by urinary system anomalies (horseshoe kidney, double collector duct system and renal rotation) detected in 16.3%. Hashimoto's thyroiditis was found in 11.1% of patients, gastrointestinal abnormalities in 8.9%, ear nose and throat problems in 22.6%, dermatologic problems in 21.8% and osteoporosis in 15.3%. Learning difficulties and/or psychosocial problems were encountered in 39.1%. Insulin resistance and impaired fasting glucose were detected in 3.4% and 2.2%, respectively. Dyslipidemia prevalence was 11.4%.Conclusion: This comprehensive study systematically evaluated the largest group of karyotype-proven TS girls to date. The karyotype distribution, congenital anomaly and comorbidity profile closely parallel that from other countries and support the need for close medical surveillance of these complex patients throughout their lifespa

Tunnelling in difficult ground: A case study from Dranaz tunnel, Sinop, Turkey

This paper presents a case study of the instability mechanisms, and the excavation sequence, re-qualification and reinforcement methods adopted to pass through a short segment of a nearly 2-km tunnel built as part of a new 55-km state highway in northern Turkey. The instability problems were encountered during tunnel excavation due to the failure to recognize the fact that alteration in stress field and resulting deformation could cause dilation and increase in the permeability of claystone-shale layers and local fault gouge zones, and in turn significant reduction in shear strength. Change in natural drainage pattern and capillarity exacerbated saturation and the consequent strength reduction. The 92-m3 loose material flowed into the tunnel due to the collapse and caused 2.5 months of delay in completion of the tunnel. Longitudinal and oblique cracks observed in shotcrete were attributed to the reduction in modulus upon saturation, which caused a large cumulative deformation of approximately 110 mm at a section about 30 m behind the collapse face.It is concluded that early detection or prediction of potentially problematic zones (via probe drilling and monitoring) in tunnelling is of paramount importance, especially through mixed or difficult ground conditions characterized by alternating layers, folding, faulting and localized zones of high water pressure. Because mechanical detection methods cannot be fully relied upon, availability of experienced personnel to predict and deal with such instability problems effectively and promptly is the best insurance for successful completion of tunnelling contracts. © 2004 Elsevier B.V. All rights reserved

Upper extremity kinematics of flat serve in tennis

The purpose of the present study was to examine of the effects of upper body kinematics on the ball velocity at the impact phase of a tennis flat serve. 15 elite male tennis players were recruited to participate in this study (mean age 18.4±3.3 years, mean height 182.3±5.6cm, mean weight 72.2±7.9kg), of which five were from the Turkish National Team. Players performed flat tennis serves on a regulation indoor tennis court. Data were recorded digitally to computer hard drives on court using three Basler A602f cameras at 100Hz. The Radar gun (Sports Radar, Astro Products, CA), was used for velocity measurements of the tennis balls. The Spearman Rank Correlation procedure was used to determine the relationships between parameters and balls. Relationships between elbow angular velocity and trunk angular velocity, as well as between elbow angular velocity and wrist angular velocity were found. The ground reaction forces transmitted through the legs and trunk allowed for greater angular velocity of the elbow, which in turn provided a favourable advantage by affecting the wrist speed and ultimately, the ball speed.Key words: Tennis; Flat serve; Biomechanics; Kinematic analysis