Non-Isotropic Angular Distribution for Very Short-Time Gamma-Ray Bursts

While most gamma-ray bursts (GRBs) are now believed to be from cosmological distances, the origin of very short-time GRBs is still not known. In the past, we have shown that GRBs with time duration (T90) less than 100 ms may form a separate class of GRBs based on the hardness and time distribution of these events. We have also shown that the ln N ln S distribution is consistent with the expectation of quasi-Euclidean distribution of sources. In this paper, we report the study of the angular location of these GRBs showing a strong deviation from isotropy within the Galactic coordinates of plus 180 degrees < longitude < 90 degrees and -30 degrees < latitude < 30 degrees. We have studied the rest of the GRBs and do not find a similar deviation. This further indicates that the very-short GRBs likely form a separate class of GRBs, most probably from sources of Galactic or near solar origin

Summary of the NOW'98 Phenomenology Working Group

Summary of the Phenomenology Working Group at the Europhysics Neutrino Oscillation Workshop (NOW'98), 7-9 September 1998, Amsterdam.Comment: 66 page

On the origin of bimodal duration distribution of Gamma Ray Bursts

The modified version of a bullet model for gamma ray bursts is studied. The central engine of the source produces multiple sub-jets that are contained within a cone. The emission of photons in the source frame of a sub-jet either takes part in an infinitesimally thin shell, or during its expansion for a finite time. The analysis of the observed profiles of GRBs taken by BATSE leads us to the conclusion that the latter possibility is much more favored. We also study the statistical distribution of GRBs, in the context of their bimodality of durations, taking into account the detector's capability of observing the signal above a certain flux limit. The model with shells emitting for a finite time is able to reproduce only one class of bursts, short or long, depending on the adopted physical parameters. Therefore we suggest that the GRB bimodality is intrinsically connected with two separate classes of sources.Comment: 12 pages, 12 figures; accepted by MNRAS. Small changes to match the corre cted proof

Condensation transition in a model with attractive particles and non-local hops

We study a one dimensional nonequilibrium lattice model with competing features of particle attraction and non-local hops. The system is similar to a zero range process (ZRP) with attractive particles but the particles can make both local and non-local hops. The length of the non-local hop is dependent on the occupancy of the chosen site and its probability is given by the parameter $p$. Our numerical results show that the system undergoes a phase transition from a condensate phase to a homogeneous density phase as $p$ is increased beyond a critical value $p_c$. A mean-field approximation does not predict a phase transition and describes only the condensate phase. We provide heuristic arguments for understanding the numerical results.Comment: 11 Pages, 6 Figures. Published in Journal of Statistical Mechanics: Theory and Experimen

Magnetic structure and charge ordering in Fe3BO5 ludwigite

The crystal and magnetic structures of the three-leg ladder compound Fe3BO5 have been investigated by single crystal x-ray diffraction and neutron powder diffraction. Fe3BO5 contains two types of three-leg spin ladders. It shows a charge ordering transition at 283 K, an antiferromagnetic transition at 112 K, ferromagnetism below 70 K and a weak ferromagnetic behavior below 40K. The x-ray data reveal a smooth charge ordering and an incomplete charge localization down to 110K. Below the first magnetic transition, the first type of ladders orders as ferromagnetically coupled antiferromagnetic chains, while below 70K the second type of ladders orders as antiferromagnetically coupled ferromagnetic chains

Structure of Tagatose-1,6-bisphosphate Aldolase. Insight into chiral discrimination, mechanism, and specificity of class II aldolases

Tagatose-1,6-bisphosphate aldolase (TBPA) is a tetrameric class II aldolase that catalyzes the reversible condensation of dihydroxyacetone phosphate with glyceraldehyde 3-phosphate to produce tagatose 1,6-bisphosphate. The high resolution (1.45 Å) crystal structure of the Escherichia coli enzyme, encoded by the agaY gene, complexed with phosphoglycolohydroxamate (PGH) has been determined. Two subunits comprise the asymmetric unit, and a crystallographic 2-fold axis generates the functional tetramer. A complex network of hydrogen bonds position side chains in the active site that is occupied by two cations. An unusual Na(+) binding site is created using a interaction with Tyr(183) in addition to five oxygen ligands. The catalytic Zn(2+) is five-coordinate using three histidine nitrogens and two PGH oxygens. Comparisons of TBPA with the related fructose-1,6-bisphosphate aldolase (FBPA) identifies common features with implications for the mechanism. Because the major product of the condensation catalyzed by the enzymes differs in the chirality at a single position, models of FBPA and TBPA with their cognate bisphosphate products provide insight into chiral discrimination by these aldolases. The TBPA active site is more open on one side than FBPA, and this contributes to a less specific enzyme. The availability of more space and a wider range of aldehyde partners used by TBPA together with the highly specific nature of FBPA suggest that TBPA might be a preferred enzyme to modify for use in biotransformation chemistry

Three-dimensional Structure of L-2-Haloacid Dehalogenase from Xanthobacter autotrophicus GJ10 Complexed with the Substrate-analogue Formate

The L-2-haloacid dehalogenase from the 1,2-dichloroethane degrading bacterium Xanthobacter autotrophicus GJ10 catalyzes the hydrolytic dehalogenation of small L-2-haloalkanoic acids to yield the corresponding D-2-hydroxyalkanoic acids. Its crystal structure was solved by the method of multiple isomorphous replacement with incorporation of anomalous scattering information and solvent flattening, and was refined at 1.95-Å resolution to an R factor of 21.3%. The three-dimensional structure is similar to that of the homologous L-2-haloacid dehalogenase from Pseudomonas sp. YL (1), but the X. autotrophicus enzyme has an extra dimerization domain, an active site cavity that is completely shielded from the solvent, and a different orientation of several catalytically important amino acid residues. Moreover, under the conditions used, a formate ion is bound in the active site. The position of this substrate-analogue provides valuable information on the reaction mechanism and explains the limited substrate specificity of the Xanthobacter L-2-haloacid dehalogenase.

Catalysis by hen egg-white lysozyme proceeds via a covalent intermediate

Hen egg-white lysozyme (HEWL) was the first enzyme to have its three-dimensional structure determined by X-ray diffraction techniques(1). A catalytic mechanism, featuring a long-lived oxo-carbenium-ion intermediate, was proposed on the basis of model-building studies(2). The `Phillips' mechanism is widely held as the paradigm for the catalytic mechanism of beta -glycosidases that cleave glycosidic linkages with net retention of configuration of the anomeric centre. Studies with other retaining beta -glycosidases, however, provide strong evidence pointing to a common mechanism for these enzymes that involves a covalent glycosyl-enzyme intermediate, as previously postulated(3). Here we show, in three different cases using electrospray ionization mass spectrometry, a catalytically competent covalent glycosyl-enzyme intermediate during the catalytic cycle of HEWL. We also show the three-dimensional structure of this intermediate as determined by Xray diffraction. We formulate a general catalytic mechanism for all retaining beta -glycosidases that includes substrate distortion, formation of a covalent intermediate, and the electrophilic migration of C1 along the reaction coordinate

Precise 3D track reconstruction algorithm for the ICARUS T600 liquid argon time projection chamber detector

Liquid Argon Time Projection Chamber (LAr TPC) detectors offer charged particle imaging capability with remarkable spatial resolution. Precise event reconstruction procedures are critical in order to fully exploit the potential of this technology. In this paper we present a new, general approach of three-dimensional reconstruction for the LAr TPC with a practical application to track reconstruction. The efficiency of the method is evaluated on a sample of simulated tracks. We present also the application of the method to the analysis of real data tracks collected during the ICARUS T600 detector operation with the CNGS neutrino beam.Comment: Submitted to Advances in High Energy Physic