(2Z,6Z)-N 2,N 2′-Bis(2,6-diisopropyl­phen­yl)-N 1,N 1′-bis­(2-methoxy­ethyl)pyridine-2,6-dicarboxamidine

In the title compound, C37H53N5O2, the benzene rings make dihedral angles of 84.61 (8) and 67.10 (9)° with the pyridine ring. The crystal structure is stabilized by strong intra­molecular inter­actions. The two (2-methoxyethyl)amine groups are disordered over two positions; the site occupancies are ca 0.6 and 0.4

Reducing the environmental impact of surgery on a global scale: systematic review and co-prioritization with healthcare workers in 132 countries

Abstract Background Healthcare cannot achieve net-zero carbon without addressing operating theatres. The aim of this study was to prioritize feasible interventions to reduce the environmental impact of operating theatres. Methods This study adopted a four-phase Delphi consensus co-prioritization methodology. In phase 1, a systematic review of published interventions and global consultation of perioperative healthcare professionals were used to longlist interventions. In phase 2, iterative thematic analysis consolidated comparable interventions into a shortlist. In phase 3, the shortlist was co-prioritized based on patient and clinician views on acceptability, feasibility, and safety. In phase 4, ranked lists of interventions were presented by their relevance to high-income countries and low–middle-income countries. Results In phase 1, 43 interventions were identified, which had low uptake in practice according to 3042 professionals globally. In phase 2, a shortlist of 15 intervention domains was generated. In phase 3, interventions were deemed acceptable for more than 90 per cent of patients except for reducing general anaesthesia (84 per cent) and re-sterilization of ‘single-use’ consumables (86 per cent). In phase 4, the top three shortlisted interventions for high-income countries were: introducing recycling; reducing use of anaesthetic gases; and appropriate clinical waste processing. In phase 4, the top three shortlisted interventions for low–middle-income countries were: introducing reusable surgical devices; reducing use of consumables; and reducing the use of general anaesthesia. Conclusion This is a step toward environmentally sustainable operating environments with actionable interventions applicable to both high– and low–middle–income countries

Mono- and binuclear ruthenium(II) complexes containing pyridine-2,6-diimine (Pydim) ligands: Synthesis, characterization and catalytic activity in the transfer hydrogenation of acetophenone

WOS: 000246908500023A series of neutral mono- and binuclear Ru(II) complexes: [PydimCl(2)RuL] (Pydim (1) pyridine-2,6-diimine; (2) L = NCMe; (3) L = PPh3) and [PydimCl(2)Ru(L-L)RuCl(2)Pydim] (4) L-L = pyrazine; (5) L-L = 4,4'-bipyridine) have been synthesized from the corresponding (p-cymene)ruthenium dichloride dimer, pydim and ancillary ligands L and L-L, respectively. The Pydim-Ru(II) complexes have been employed as catalysts for the transfer hydrogenation of acetophenone in the presence of KOH using 2-propanol as a hydrogen source. Ligand substitution studies indicate that there is a significant difference in reactivity between complexes containing L/L-L and Pydim. Yields of up to 93% were obtained after 5 min at 82 degrees C. (C) 2007 Elsevier B.V. All rights reserved

Synthesis of some ruthenium(II)-Schiff base complexes bearing sulfonamide fragment: New catalysts for transfer hydrogenation of ketones

Four new ruthenium(II) complexes [RuCl(1-4)(p-cymene)] (1-4 = N-(3-(2-hydroxybenzylideneamino)phenyl) benzenesulfonamides) were synthesized from [RuCl2(p-cymene)](2) with Schiff base ligands containing aromatic sulfonamide fragment, and characterized by spectroscopic techniques including H-1 and C-13 NMR, FT-IR, single crystal X-ray diffraction and by elemental analysis. Additionally, all the synthesized Ru(II) complexes were tested as catalysts for the reactions in the transfer hydrogenation (TH) of acetophenone derivatives. The results showed that these facile synthesized Ru(II) complexes are efficient catalysts in this reaction (turnover frequency: 1260 h(-1) for 6). (C) 2014 Elsevier B. V. All rights reserved

Ruthenium(II) complexes bearing pyridine-based tridentate and bidentate ligands: catalytic activity for transfer hydrogenation of aryl ketones

WOS: 000312137900002Ru(II) complexes of the general formula [RuCl2('NNN??')(L)] (1: 'N?=?Nb, L?=?MeOH; 2: 'N?=?Nb, L?=?CH3CN; 3: 'N?=?Nd, L?=?CH3CN; 4: 'N?=?Np, L?=?CH3CN), [Ru(p-cymene)(NN?ab)Cl]Cl (5a: N?Na?=?2,2'-bipyridine; 5b: N?Nb?=?4,4'-dimethyl2,2'-bipyridine), [Ru('NNN??')(NN?ab)Cl]Cl (6a: 'N?=?Nb, NN?a?=?2,2'-bipyridine; 6b: 'N?=?Nb, NN?b?=?4,4'-dimethyl-2,2'-bipyridine; 7a: 'N?=?Nd, NN?a?=?2,2'-bipyridine; 7b: 'N?=?Nd, NN?b?=?4,4'-dimethyl-2,2'-bipyridine; 8a: 'N?=?Np, NN?a?=?2,2'-bipyridine; 8b: 'N?=?Np, NN?b?=?4,4'-dimethyl-2,2'-bipyridine) and [Ru('NNN??')(NN?a)Cl]BF4 (9a: 'N?=?Nb; NN?a?=?2,2'-bipyridine) were synthesized from the corresponding [RuCl2(p-cymene)]2 dimer, 'NNN??' and NN?ab ligands. The compounds were characterized by elemental analysis, IR and NMR. Complex 9a was studied by X-ray diffraction, confirming its cationic-mononuclear [RuCl(bNNN??b)(NN?a)]+ nature. The synthesized Ru(II) complexes (18) were employed as catalysts for the transfer hydrogenation of ketones to secondary alcohols in the presence of KOH using 2-propanol as a hydrogen source at 82 degrees C. The rates of the transfer hydrogenation reactions strongly depended on the type of NNN?? and ancillary ligands. Copyright (C) 2012 John Wiley & Sons, Ltd.Scientific and Technical Research Council of Turkey (TUBITAK)Turkiye Bilimsel ve Teknolojik Arastirma Kurumu (TUBITAK) [107T808]This research has been supported by the Scientific and Technical Research Council of Turkey (TUBITAK) (project no. 107T808). The authors are grateful to Anadolu University and the Medicinal Plants and Medicine Research Centre of Anadolu University, Eskisehir, Turkey, for the use of the X-ray diffractometer