Original Article - Comparison of the efficacy of topical 1% lindane vs 5% permethrin in scabies: A randomized, double-blind study

Background: Permethrin, a pyrethroid insecticide, is not yet available in Iran and may be a useful substitute for the control of scabies in Iran. Aim: To compare the efficacy of topical lindane with topical permethrin in the treatment of scabies in a population in Iran. Methods: In a double-blind, randomized study, all consecutive patients with scabies were randomized into two groups. One group and their family contacts received 1% lindane cream, and the other group and their family contacts were treated with topical 5% permethrin cream. Subsequently, patients were followed up at 2- and 4-week post-treatment. Results: Of the 99 patients enrolled in the study, 47 patients received 1% lindane cream, and 52 patients were treated topically with 5% permethrin cream. Permethrin provided an improvement rate of 84.6% after two weeks, whereas lindane was effective only in 48.9% of patients. Conclusion: Permethrin (5%) cream was found to be significantly more effective in the treatment of scabies in comparison with lindane in this study, and it seems that it could be an alternative treatment

The Spine Vertebral Bodies 3D Modeling and its Biomechanical Advantages

To perform an accurate approach to the spine specially for fracture stabilization a 3D model of spine surgical region may improve this mechanism and it can help the surgeon to have a deeper glance to this scenario. The pre-op planning facility is another advantage of the patient spine specific model to take a chance of making guides to direct pedicle screws safely and increase the pathomechanics of volumes of interest stability factor parallel with its mobility restoration. There are some algorithms for making 3D-reconstruction from CT or MR data-set but the main goal of in-vivo component 3D making is right component extraction from its peripheral segments to achieve the best judgment especially about the surgical approach. Here is a cervical vertebral bodies segmentation and 3D-reconstruction of two cervical adjacent levels combined with the registration process that is shown the intervertebral degree regarding to range of motion percent