Enhancing Splinting Confidence through Inter-Residency Education: An Educational Workshop

Introduction. The initial treatment for many orthopaedic injuries is splinting. Unfortunately, formal musculoskeletal training is limited in primary care leading to deficiencies in competency and confidence. Suboptimal splints can result in complications such as skin breakdown, worsening of deformity, and increased pain. Our orthopaedic surgery clinic often cares for patients who initially present to an emergency department or primary care clinic for their orthopaedic injury. Previous studies have shown that a high number of splints are applied improperly in the primary care setting, which could result in in avoidable skin complications and fracture instability. Methods. Orthopaedic surgery residents held a splinting workshop for family medicine residents. The workshop involved didactic and skills portions. Pre- and post-surveys were administered using a 10-point scale to assess confidence in applying three common splints. The data were analyzed using student’s t-test and qualitative feedback. Results. Confidence in applying and molding each splint type improved significantly (p < 0.05). Knowledge in splint construction improved significantly as well (p < 0.05). Subjective feedback was positive. Conclusion. These results showed inter-residency education can increase residents’ confidence in skill-based medical care significantly. The results are encouraging and should facilitate further collaboration between multispecialty residency programs to improve patient care. Further investigation is needed to determine how well skills gained in workshop are retained

SOLID DISPERSIONS: RESUSCITATING ORAL DELIVERY OF HYDROPHOBIC DRUGS

Objective: This review article explores solid dispersions (SDs) as one of the suitable approaches to formulate poorly water-soluble drugs. The objective of this review on SD techniques is to explore their utility as a feasible, simple, and economically viable method for augmentation of dissolution of hydrophobic drugs. Methods: Various types of SDs are classified and compared. Use of surfactants to stabilize the SDs and their potential advantages and disadvantages has been discussed. Different techniques for preparing and evaluating SDs are appraised along with discussions on scalability and industrial production. Review of the current research on SD along with future trends is also offered. Results: Based on the various researches, SDs offer an efficient means of improving bioavailability while concurrently contributing to lower toxicity and dose-reduction. Conclusion: Solid-dispersions have been and continue to be one of the key technologies for solving the issue of poor solubility for newer hydrophobic molecules which are being discovered. This would give a new lease of life for such drugs enabling them to be delivered in an effective way

Examining the Role of CtEG using Drosophila

This project focused on creating viable drosophila models that could be used to evaluate and understand the significance of the N-tarp portion in the effector genes of Chlamydia Trachomatis. During our project we performed multiple DNA clean ups, PCR\u27s, gel electrophoresis, double digestions, and DNA ligations. In this we learned not only the methodological importance within these laboratory techniques but that a great deal of learning occurs in being able to evaluate and analyze ways to troubleshoot when intended results from an experiment are not observed.https://stars.library.ucf.edu/hip-2023fall/1045/thumbnail.jp

A Critical Review on Go-Ghrita, Shata Dhouta Ghrita and Sahasra Dhouta Ghrita

Traditional medical system has always played an important role in the maintenance of health of mankind. Modern medicine has been drawing inputs from these traditional systems since their very beginning. Samskara in Ayurveda, is a process of transformation of inherent attributes of a substance. This is created by dilution, application of heat, cleansing, churning, storing in a specific place, maturing, flavoring, impregnation, preservation, container etc. Ancient scholars considered that Ghrita is able to perform multiple actions if processed accordingly. On the base of this, many Samskaras are employed for Ghrita and subsequently various pharmacological actions are observed. Shatadhouta Ghrita and Sahsradhouta Ghrita are also an outcome of that keen observation. Shatadhouta Ghrita and Sahasradhouta Ghrita are two Ayurvedic preparations, which are prepared by washing cow ghee for hundred and thousand times respectively. They are considered as best alleviators of Pitta Dosha and burning sensation, in the treatments of wound healing. On the basis of detailed literary review, it was understood that, Shatadhouta Ghrita and Sahasradhouta Ghrita should be prepared by pressure washing of Ghrita with water. These preparations are indicated for Dahashamana action. Both of them have the properties as that of oil in water kind of emulsion

Perception of caregivers regarding danger signs of childhood diarrhea and attitude towards its management in rural Lucknow, UP, India

Background: Diarrhoea is a major cause of morbidity and mortality in children. Most deaths are caused by dehydration and are easily preventable by using oral rehydration therapy. Early management and recognition of danger signs are key strategies in treating diarrhoeal diseases at home. Aims & Objectives: 1. To assess the knowledge of caregivers regarding childhood diarrhoea and signs of dehydration and danger signs, 2. To assesses the mothers’ approach towards its home based management and health seeking behaviour. Material & Methods: A community based cross sectional study was conducted in different rural blocks of Lucknow selected by multistage sampling. Total of 240 households were interviewed to achieve targeted sample size of 410 children of less than five years age group. Perception of diarrhoea, signs of dehydration and danger signs were asked to caregivers and associations were established maternal knowledge and presence or absence of diarrhoea in children of less than five age group. Results: The study showed that 74.2 per cent of caregivers recognized diarrhoea correctly i.e. increased frequency of watery stool or blood and mucus in stool or both. Decreased urination or dis-coloured urine (89.6%), thirsty or eagerly drinking (55.7%), dry mouth and tongue (37.7%) etc. were recognized by caregivers as major signs of dehydration*. Caregivers recognized child getting seeker/ unconscious (94.9%), not able to drink or breast feed (66.7%), blood in stool (59%) etc. as danger signs* developing during diarrhoea episodes of child.  Conclusions: Caregiver’s knowledge regarding recognition of childhood diarrhoea in proper and early detection of signs of dehydration and development of danger signs at community level are keys to prevention of diarrhoea related death in less than five years age group

Functional Meat and Meat Products: An Overview

A food can be regarded as functional if it is satisfactorily demonstrated to beneficially affect one or more target functions in the body, beyond adequate nutritional effects, in a way that is relevant to either improved health or well-being and/or to a reduction in the risk of disease. They are very important for health and are classified on various basis such as Supplementation of functional ingredients in diets of animals which includes Conjugated linoleic acid, Vitamin E, Omega-3 (ω3) fatty acids and Selenium; enrichment of functional ingredients in meat and meat products which includes functional foods from plant sources such as Soy proteins, Wheat proteins, Fibers, Broccoli and other Cruciferous Vegetables, Citrus Fruits, Tomatoes, Flaxseed, Herbs and spices as well as functional foods from animal sources such as Fish and Dairy Products like Whey protein and Probiotics and finally production of functional components during processing which includes Curing, Fermentation, Production of antibacterial compounds like Bacteriocin and Enzyme hydrolysis of proteins. Current status of functional meat products in world and India, safety issues and future prospects has been discussed

Cultivation of Black Goji Berry (Lycium Ruthenicum Murr.) in the Trans Himalayan Region Ladakh Agro Technique Harvest, Yield and Cost Benefit Analysis

The present study discusses the agro technique, harvesting, yield, and economics of less explored highly medicinal plant black goji berry (Lycium ruthenicum). It was observed that black goji berries can be easily cultivated through seed, pencil-thickness hardwood stem cuttings, and rootstock. Black goji berry harvesting is a very difficult and tedious task for goji growing farmers as the berries get easily ruptured during harvesting and lose their content. To address these obstacles, DIHAR-DRDO, Leh conducted several goji berry harvesting trials deploying various techniques. Collecting fruits/berries to their full potential requires careful planning and tactics, which involves the use of an appropriate harvesting method that minimizes damage. After performing various method of harvesting, the best outcome was reported in cutting the fruit-bearing branch method as its less expensive with minimum fruit damage (5 %), time-saving, and retain the quality of fruit as compared to the other harvesting methods. An approximate cost production and net profit calculation were performed for 1011.71 square meters (02 Kanal) plantations of L. ruthenicum to their average yield of fruit production per plant. The average yield of three-year-old hardwood stem cutting and uprooted plant is 500-600 gm of fresh berry per plant on average. The economic relation to the cost production of L. ruthenicum is highly beneficial and it has all the capabilities of enhancing the socio-economy of the fragile ecosystem