Wind optimal flight trajectories to minimise fuel consumption within a 3 dimensional flight network

This paper assesses the potential fuel savings benefits that can be gained from wind optimal flight trajectories. This question is posed on a 3 dimensional fixed flight network consisting of discrete waypoints which is representative of the size of Europe. The optimisation implements Dijkstra's shortest path algorithm to compute the minimum fuel burn route through a network and compares this to the fuel burn for the shortest distance route. Particular effort is applied to testing the repeatability and robustness of the results. This is achieved through a sensitive analysis based on a number of identified model parameters relating to the setup of the flight network. The results of this study show fuel savings between 1.0%-10.3%, and suggest that the benefits of wind optimal flight trajectories are significant

Isotope shift in the Sulfur electron affinity: observation and theory

The electron affinities eA(S) are measured for the two isotopes 32S and 34S (16752.9753(41) and 16752.9776(85) cm-1, respectively). The isotope shift in the electron affinity is found to be positive, eA(34S)-eA(32S) = +0.0023(70) cm-1, but the uncertainty allows for the possibility that it may be either "normal" (eA(34S) > eA(32S)) or "anomalous" (eA(34S) < eA(32S)). The isotope shift is estimated theoretically using elaborate correlation models, monitoring the electron affinity and the mass polarization term expectation value. The theoretical analysis predicts a very large specific mass shift that counterbalances the normal mass shift and produces an anomalous isotope shift, eA(34S)-eA(32S) = - 0.0053(24) cm-1. The observed and theoretical residual isotope shifts agree with each other within the estimated uncertainties.Comment: 15 pages, 4 figure

Qualitative research: exploring the multiple perspectives of osteopathy

This paper is offered as an introduction to qualitative research, with the hope that it informs and stimulates osteopaths and researchers who are unfamiliar with this area of research. This paper discusses the potential contribution of qualitative research in exploring the complex and multiple aspects of osteopathy and how the findings of qualitative studies may contribute to the knowledge base of osteopathy. A definition of qualitative research is provided, and a number of different methodologies are discussed. Finally it suggests examples of how the findings of qualitative research could potentially help inform osteopathic practice. © 2011 Elsevier Ltd

Extreme star formation events in quasar hosts over 0.5<z<4{\bf0.5<\textit{z}<4}

We explore the relationship between active galactic nuclei and star formation in a sample of 513 optically luminous type 1 quasars up to redshifts of $\sim$4 hosting extremely high star formation rates (SFRs). The quasars are selected to be individually detected by the \textit{Herschel} SPIRE instrument at $>$3$\sigma$ at 250 $\mu$m, leading to typical SFRs of order of 1000 M$_{\odot}$yr$^{-1}$. We find the average SFRs to increase by almost a factor 10 from $z\sim0.5$ to $z\sim3$, mirroring the rise in the comoving SFR density over the same epoch. However, we find that the SFRs remain approximately constant with increasing accretion luminosity for accretion luminosities above 10$^{12}$ L$_{\odot}$. We also find that the SFRs do not correlate with black hole mass. Both of these results are most plausibly explained by the existence of a self-regulation process by the starburst at high SFRs, which controls SFRs on time-scales comparable to or shorter than the AGN or starburst duty cycles. We additionally find that SFRs do not depend on Eddington ratio at any redshift, consistent with no relation between SFR and black hole growth rate per unit black hole mass. Finally, we find that high-ionisation broad absorption line (HiBAL) quasars have indistinguishable far-infrared properties to those of classical quasars, consistent with HiBAL quasars being normal quasars observed along a particular line of sight, with the outflows in HiBAL quasars not having any measurable effect on the star formation in their hosts.Comment: 12 pages, 6 figure

The Democratic Foundations of the Just City

Key Insights From a European Comparative Study

Performance Studies of the Acoustic Module for the IceCube Upgrade

The IceCube Upgrade will augment the existing IceCube Neutrino Observatory by deploying 700 additional optical sensor modules and calibration devices within its center at a depth of 1.5 to 2.5 km in the Antarctic ice. One goal of the Upgrade is to improve the positioning calibration of the optical sensors to increase the angular resolution for neutrino directional reconstruction. An acoustic calibration system will be deployed to explore the capability of achieving this using trilateration of propagation times of acoustic signals. Ten Acoustic Modules (AM) capable of sending and receiving acoustic signals with frequencies from 5 to 30 kHz will be installed within the detector volume. Additionally, compact acoustic sensors inside 15 optical sensor modules will complement the acoustic calibration system. With this system, we aim for an accuracy of a few tens of cm to localize the Acoustic Modules and sensors. Due to the longer attenuation length of sound compared to light within the ice, acoustic position calibration is especially interesting for the upcoming IceCube-Gen2 detector, which will have a string spacing of around 240 m. In this contribution we present an overview of the technical design of the Acoustic Module as well as results of performance tests with a first complete prototype.Comment: Presented at the 38th International Cosmic Ray Conference (ICRC2023). See arXiv:2307.13048 for all IceCube-Gen2 contribution

Towards NEWS 3.0: development and validation of an oxygen therapy adjusted National Early Warning Score. A statistical analysis plan

Introduction Early warning scores (EWS) use routinely measured vital signs to identify patients at risk of deterioration. The National Early Warning Score 2 (NEWS2) is mandated for use by NHS England in all acute trusts. Within NEWS2, oxygen therapy is scored using a binary approach — patients receive 2 points if they are receiving supplemental oxygen and 0 points if they are breathing room air. Examples of binary oxygen EWS are widespread, including other nationally employed EWS. Some have expressed concerns that deterioration is missed when patients require an escalating amount of supplemental oxygen in the absence of other vital sign derangements. This study aims to adapt and validate a version of NEWS2 that accounts for the amount of supplemental oxygen therapy the patient receives (NEWS2-O2). Methods We will use data from four NHS healthcare trusts across the UK to develop and validate an oxygen therapy adjusted NEWS2 score. We will also explore the time trends of oxygen requirement and other vital signs prior to deterioration. We will perform an external validation of other oxygen adjusted vital sign only EWS identified in a prior systematic review. Generalisability and implications This work will explore the quantification and handling of oxygen therapy within an EWS. We aim to provide an example to the NEWS Development Group on how oxygen can be incorporated into the next iteration of NEWS