Tratamento de sementes de pimentão com microrganismos, micronutrientes, aminoácidos e reguladores de crescimento

Small sized seeds, such as the horticultural species, have limited quantities of reserves that can be balanced by coating then with essential nutrients for their initial development. In addition, inoculation of the seeds with microorganisms may protect the plants against phytopathogens, thus enhancing their growth. The present work had the objective of evaluate the physiological quality and seedling development of sweet pepper seeds and seedlings coated with several kind of films. Seeds were first coated with polymers and then with antagonistic microorganisms (Trichoderma viride, Trichoderma polysporhum, Trichoderma stromaticum, Beauveria bassiana, Metarhizium anisopliae), mycorrhizas, aminoacids, micronutrients and plant growth regulators. Evaluation was performed for percentage of germination and for seedling emergence, speed of emergence index, number of plants, dry mass of the aerial and root parts and height of the seedlings. Inoculation with Trichoderma viride increased the percentage and rate of the seedlings emergence Inoculation with Trichoderma viride, Metarhizium anisopliae and mycorrhizas promote better seedling development; seed microbiolization with microorganisms Trichoderma viride, T. polysporhum, T. stromaticum, Beauveria bassiana, Metarhizium anisopliae. Mycorrhizas mixture negatively affected seeds and seedling quality. Seed covering with plant growht regulator, at a 5 mL kg-1 dose increased the roots dry matter.Em sementes pequenas, como as de espécies hortícolas, as limitadas quantidades de reservas podem ser equilibradas por meio do seu recobrimento com nutrientes essenciais para o seu desenvolvimento inicial. Além disso, a inoculação dessas sementes com microrganismos, além de proteger as plantas contra fitopatógenos, pode promover o seu crescimento. Assim, objetivo do presente trabalho foi avaliar o efeito de tipos de revestimentos na qualidade de sementes e mudas de pimentão (Capsicum annum). Para tanto, as sementes foram primeiro revestidas com polímeros e depois foram adicionados microrganismos antagônicos (Trichoderma viride, Trichoderma polysporhum, Trichoderma stromaticum, Beauveria bassiana, Metarhizium anisopliae), micorrizas, aminoácidos, micronutrientes e reguladores vegetais. Avaliaram-se a porcentagem de germinação e de emergência, o índice de velocidade de emergência, o número de plantas, a massa seca de parte aérea e de raiz e a altura da parte aérea das mudas. A inoculação de sementes com Trichoderma viride aumentou a porcentagem e o índice de velocidade de emergência das plântulas; Trichoderma viride, Metarhizium anisopliae e as micorrizas inoculadas às sementes dessa espécie promovem melhor desenvolvimento das mudas; a microbiolização de sementes com a mistura dos microrganismos Trichoderma viride, T. polysporhum, T. stromaticum, Beauveria bassiana, Metarhizium anisopliae e micorrizas afetou negativamente a qualidade das sementes e mudas de pimentão e o revestimento dessas sementes com regulador vegetal, na dose de 5 mL kg-1 de sementes proporciona aumento na massa seca das raízes das plantas

Agenesia e lipoma de corpo caloso: relato de caso

The agenesis and lipoma of the corpus callosum is a very rare association. We report the case of a 18-years old woman with rare epileptic seizures since the age of 6 years, normal neurological examination, as well as normal electroencephalogram. The brain computed tomography scanning and the magnetic resonance showed the lipoma and the agenesis of the corpus callosum.A agenesia e lipoma do corpo caloso é uma associação muito rara. Relatamos o caso de uma paciente de 18 anos com raras crises epilépticas desde os 6 anos de idade, exame neurológico normal, assim como eletrencefalograma normal. A tomografia computadorizada de crânio e a ressonância magnética mostraram o lipoma e a agenesia de corpo caloso.Escola Paulista de MedicinaUNIFESP, EPMSciEL

IMPACTO DA EDUCAÇÃO SUPERIOR PARA A MOBILIDADE SOCIAL

Na ultima década tivemos um aumento expressivo de pessoas cursando o nível superior no Brasil. A literatura internacional faz uma relação direta entre nível de escolaridade e renda per capita dos países, porém não há trabalhos no contexto do Oeste Paulista. O objetivo deste trabalho foi quantificar se temos os mesmos padrões internacionais da mobilidade social, medindo a renda, os níveis de empreendedorismo e, a satisfação social. Para tal foram pesquisados egressos dos últimos 7 anos do curso de Administração de Empresas de uma universidade no Oeste Paulista, aplicando questionários elaborados segundo a escala Likert e, estudando dados secundários oficiais do IBGE e RAIS. Observou-se que as melhorias socioeconômicas dos ex-alunos estudados são superiores ao relatado na literatura internacional e a média nacional. Ao mesmo tempo foi detectado que o nível de empreendedorismo local é inferior ao nível nacional e o gap entre gêneros dos egressos também esta acima da média nacional.

Influence of CYP19A1 gene expression levels in women with breast cancer: a systematic review of the literature

Breast cancer is the most frequently diagnosed malignant neoplasm in women and is considered a multifactorial disease of unknown etiology. One of the major risk factors is genetic alteration. Changes in CYP19A1 gene expression levels have been associated with increased risk and increased aggressiveness of breast cancer. Increased CYP19A1 gene expression and/or aromatase activity are among the major regulatory events for intratumoral production of estrogens in breast malignant tissues. This systematic review aimed to investigate the influence of CYP19A1 gene expression levels in women with breast cancer. The research was carried out using the PubMed, Scopus, and Web of Science databases. Searches were conducted between February 2 and May 15, 2019. Inclusion criteria were studies published between 2009 and 2019, English language publications, and human studies addressing the gene expression of CYP19A1 in breast cancer. A total of 6.068 studies were identified through PubMed (n=773), Scopus (n=2,927), and the Web of Science (n=2,368). After selecting and applying the inclusion and exclusion criteria, six articles were included in this systematic review. This systematic review provides evidence that increased or decreased levels of CYP19A1 gene expression may be related to pathological clinical factors of disease, MFS, OS, DFS, WATi, markers of metabolic function, concentrations of E1, FSH, and in the use of multiple exons 1 of the CYP19A1 gene in breast cancer

Mining clinical attributes of genomic variants through assisted literature curation in Egas

The veritable deluge of biological data over recent years has led to the establishment of a considerable number of knowledge resources that compile curated information extracted from the literature and store it in structured form, facilitating its use and exploitation. In this article, we focus on the curation of inherited genetic variants and associated clinical attributes, such as zygosity, penetrance or inheritance mode, and describe the use of Egas for this task. Egas is a web-based platform for text-mining assisted literature curation that focuses on usability through modern design solutions and simple user interactions. Egas offers a flexible and customizable tool that allows defining the concept types and relations of interest for a given annotation task, as well as the ontologies used for normalizing each concept type. Further, annotations may be performed on raw documents or on the results of automated concept identification and relation extraction tools. Users can inspect, correct or remove automatic text-mining results, manually add new annotations, and export the results to standard formats. Egas is compatible with the most recent versions of Google Chrome, Mozilla Firefox, Internet Explorer and Safari and is available for use at https://demo.bmd-software.com/egas/

Pharmacological Activity of \u3ci\u3eCostus spicatus\u3c/i\u3e in Experimental \u3ci\u3eBothrops atrox\u3c/i\u3e Envenomation

Context: Medicinal plants encompass a rich source of active compounds that can neutralize snake venoms or toxins. Costus spicatus (Jacq.) Sw. (Costaceae) is used by the Amazonian population to treat inflammation, pain and other pathological manifestations. Objective: To evaluate the influence of C. spicatus aqueous extract on edema, peritonitis, nociception, coagulation, haemorrhage and indirect haemolytic activity induced by Bothrops atrox venom (BAV). Materials and methods: Dried and pulverized leaves were extracted with distilled water. Envenoming was induced by administration of B. atrox snake venom in Swiss Webster mice. The experimental groups consisted of BAV (at the minimum dose to induce measurable biological responses) and C. spicatus extract (CSE, 1.25, 2.5, 5.0, 7.5 and 10 mg/kg/25 ml phosphate-buffered saline) administered individually and in combination (BAVCSE). PBS was used as a control. In vitro assays were also conducted in order to evaluate phospholipase A2 coagulant activities (indirect haemolytic method). Results: CSE significantly reduced the venom-induced edema and nociception at all concentrations tested and inhibited migration of inflammatory cells at the three least concentrations (5.0, 7.5 and 10 mg/kg/25 ml PBS). CSE was not effective in inhibiting coagulant, haemorrhagic and indirect haemolytic activities of the venom. Discussion and conclusion: The data suggest that CSE could exhibit a central mechanism for pain inhibition, and may also inhibit prostaglandin synthesis. These findings corroborate the traditional administration of C. spicatus decoction to treat inflammatory disorders, including those caused by B. atrox envenomation

Cinema indígena: de objeto a sujeito da produção cinematográfica no Brasil

Baseado nos Estudos Culturais, o presente artigo reflete sobre uma experiência de produção cinematográfica junto a um grupo de jovens da etnia Sateré-Mawé, habitante da Amazônia brasileira. Localizamos a experiência em um contexto histórico e político mais amplo do Cinema Indígena. Abordamos as principais características do Cinema Brasileiro no decorrer do século XX e sua relação com movimentos nacionalistas na construção da imagem do índio. Focamos o Cinema Novo como uma ruptura com os padrões hollywoodianos da indústria cinematográfica brasileira da época a partir do neorrealismo italiano e da Nouvelle Vague francesa, na hipótese historiográfica e epistemológica de preparação de uma base ideológica e metodológica para a emergência futura do Cinema Indígena. Não perdemos de vista o Cinema e o Cinema Indígena nas Américas, principalmente em face das problemáticas relativas à identidade nacional no bojo das políticas culturais dos Estados nacionais que afetam diretamente a diversidade étnica em seus territórios. Com base nesse contexto, prosseguimos com uma compreensão do projeto “Cineastas Indígenas” da ONG “Vídeo nas Aldeias” enquanto um dispositivo teórico e metodológico a ser multiplicado e transformado.En base a los estudios culturales, este artículo reflexiona sobre la experiencia de la producción de la película con un grupo de jóvenes de etnia Sateré-Mawé, habitantes de la Amazonia brasileña. La experiencia se localiza en un contexto histórico y político más amplio del cine indígena. Se discuten las principales características del cine brasileño en el siglo XX y su relación con los movimientos nacionalistas en la construcción de la imagen del indígena. Se centra en el Cinema Novo como una ruptura con los estándares de Hollywood de la industria cinematográfica brasileña en la época del neorrealismo italiano y de la Nouvelle Vague francesa, en la hipótesis historiográfica y epistemológica de preparación de una base ideológica y metodológica para la futura aparición del cine indígena. No se pierde de vista el cine y el cine indígena en el continente americano, principalmente de cara a los problemas de la identidad nacional, en medio de las políticas culturales de los Estados nacionales que afectan directamente a la diversidad étnica en sus territorios. Sobre la base de este marco, se procede a una comprensión del proyecto “Cineastas Indígenas” de la ONG “Video en las Aldeas” como un dispositivo teórico y metodológico a ser multiplicado y transformado.Based on cultural studies, this article refers to a cinematographic production experienced by a group of Sateré Mawé youngsters, inhabitants of the brazilian Amazon. We tried to set this experience in a broader historical and political context of indigenous cinema. We discuss the main features corcerning brazilian cinema during the twentieth century and its relationship to nationalist movements in the building of indigenous people image. We focused on Cinema Novo as a break with Hollywood standards, working with the assumption of it as an ideological and epistemological basis for the future emergence of Indigenous Cinema. We specially emphasized the indigenous cinema on America, concerning to questions related to national identity, within culture politics of the national States which directly affect ethnic diversity in their territories. In this context, we discuss the “Cineastas Indígenas” project, realized by the NGO “Video nas Aldeias” as an important theoretical and methodological tool, that must be transformed and multiplyed

Perspectives on the Zika outbreak: herd immunity, antibody-dependent enhancement and vaccine

Submitted by Adagilson Silva ([email protected]) on 2017-05-05T18:22:21Z No. of bitstreams: 1 zika17abr25.pdf: 150751 bytes, checksum: 7c2ffa760d310a51900bc0b7bc387677 (MD5)Approved for entry into archive by Adagilson Silva ([email protected]) on 2017-05-05T18:26:57Z (GMT) No. of bitstreams: 1 zika17abr25.pdf: 150751 bytes, checksum: 7c2ffa760d310a51900bc0b7bc387677 (MD5)Made available in DSpace on 2017-05-05T18:26:57Z (GMT). No. of bitstreams: 1 zika17abr25.pdf: 150751 bytes, checksum: 7c2ffa760d310a51900bc0b7bc387677 (MD5) Previous issue date: 2017Fundação Oswaldo Cruz. Centro de Pesquisas Aggeu Magalhães. Departamento de Virologia e Terapia Experimental. Recife, PE, Brazil.Universidade Federal de Pernambuco. Laboratório de Imunopatologia Keizo Asami. Setor de Virologia. Recife, PE, Brazil.Fundação Oswaldo Cruz. Centro de Pesquisas Aggeu Magalhães. Departamento de Virologia e Terapia Experimental. Recife, PE, Brazil.Fundação Oswaldo Cruz. Centro de Pesquisas Aggeu Magalhães. Departamento de Virologia e Terapia Experimental. Recife, PE, Brazil.Fundação Oswaldo Cruz. Centro de Pesquisas Aggeu Magalhães. Departamento de Virologia e Terapia Experimental. Recife, PE, Brazil