Cardiac involvement in COVID-19: a matter close to the heart, beyond the acute illness

© 2023 International Journal of Cardiovascular Sciences. This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.Human infection with the SARS-CoV-2 virus and COVID-19 have been ravaging the entire world since December 2019. As of February 17, 2023, records from the World Health Organization point to more than 756 million confirmed cases and approximately 6,845,000 deaths. In Brazil, until this date, approximately 36,961,000 cases have been reported, with about 698,000 deaths.Among the deaths, the main comorbidities reported are heart disease (40%), diabetes (28%), obesity (10%), neurological diseases (5%), kidney diseases (5%), and pneumopathies (5%). Furthermore, 70% of patients who died were 60 years old or older, and males were prevalent in 60% of the cases.info:eu-repo/semantics/publishedVersio

COVID-19 : a matter close to the heart

© This is an open-access article distributed under the terms of the Creative Commons Attribution License 4.0 International – CC BYThe world is facing a new challenge, the novel coronavirus disease 2019 (COVID-19), caused by a betacoronavirus named severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), phylogenetically identical to the SARS-CoV (severe acute respiratory syndrome coronavirus) and the MERS-CoV (Middle East respiratory syndrome coronavirus) responsible for innumerable deaths in China in 2003 and in the Middle East in 2012, respectively.info:eu-repo/semantics/publishedVersio

Covid-19 and Safety in the Cath Lab: Where We Are and Where We Are Headed

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Fetal and maternal factors are associated with mortality due to circulatory system disorders in children

OBJECTIVE: To analyze the association of characteristics recorded at the time of birth, including weight, occurrence of asphyxia, gestation duration, maternal age and education level, with death from diseases or malformations of the circulatory system in children under 18 years of age. METHODS: The Brazilian Information System on Live Births and Information System on Mortality databases were linked and evaluated following a longitudinal cohort analysis strategy. The following independent variables were evaluated: characteristics recorded at the time of birth, including weight, occurrence of asphyxia, gestation duration, maternal age and education level. Dependent variables were death from diseases or malformations of the circulatory system in children under 18 years of age. Crude relative risks were estimated and relative risks were adjusted for the variables. RESULTS: 6,380 deaths were linked to 4,282,260 birth records, yielding 5,062 pairs considered as true. Low birth weight (RR = 2.26), asphyxia at 1 (RR = 1.72) and 5 minutes (RR = 1.51), prematurity (RR = 1.50), maternal age ≥ 40 years (RR = 2.06), and low maternal education level (RR = 1.45) increased the probability of death caused by circulatory system diseases. In the association with death by malformations of the circulatory system, the predictive variables showed the same association profile, but with greater intensity. CONCLUSIONS: Fetal and maternal factors are associated with increased mortality due to diseases and malformations of the circulatory system. Measures to control these factors and improve access to their diagnosis and treatment would contribute to reducing the number of deaths caused by diseases and malformations of the circulatory system. However, the identification of environmental influences during gestation and birth on the risk of death should be carefully considered due to being influenced by genetic factors

The Best Articles of 2022 in the Arquivos Brasileiros de Cardiologia and Revista Portuguesa de Cardiologia

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RELAÇÃO ENTRE AMPLITUDE DE MOVIMENTO DE QUADRIS, JOELHOS E TORNOZELOS E A OCORRÊNCIA DE QUEDAS EM IDOSOS INSTITUCIONALIZADOS

Estudar a relação entre a amplitude de movimento de quadris, joelhos e tornozelos com a ocorrência de quedas em idosos. Estudo descritivo transversal realizado com 39 idosos institucionalizados na Casa dos Idosos Vila Mutirão em Goiânia (Goiás, Brasil). Foram constituídos dois grupos, idosos caidores (n = 16) e idosos não caidores (n = 14). A amplitude de movimento dos quadris, joelhos e tornozelos foi avaliada por meio da goniometria. Foram feitas análises estatísticas descritivas para todas as variáveis e para a comparação entre os grupos foram utilizados o teste T-Studant, no nível de significância de 5%. Houve diferenças estatisticamente significativas entre os grupos para as variáveis sexo, renda e escolaridade e não houve diferenças significativas entre os grupos para a amplitude de movimento de quadris, joelhos e tornozelos. Embora sem diferença estatisticamente significativa entre os grupos, percebemos menor amplitude de movimento entre os idosos caidores. A restrição da mobilidade está associada a ocorrência de quedas em idosos, sendo essa limitação passível de intervenção fisioterapêutica. Fazem-se necessários programas de exercícios terapêuticos a fim de prevenir eventos adversos como as quedas em idosos

COVID-19 and Hypercoagulable State: A New Therapeutic Perspective

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Effects of the Topical Application of Hydroalcoholic Leaf Extract of Oncidium flexuosum Sims. (Orchidaceae) and Microcurrent on the Healing of Wounds Surgically Induced in Wistar Rats

This study evaluated the wound healing activity of hydroalcoholic leaf extract of Oncidium flexuosum Sims. (Orchidaceae), an important native plant of Brazil, combined or not with microcurrent stimulation. Wistar rats were randomly divided into four groups of nine animals: control (C), topical application of the extract (OF), treated with a microcurrent (10 μA/2 min) (MC), and topical application of the extract plus microcurrent (OF + MC). Tissue samples were obtained 2, 6, and 10 days after injury and submitted to structural and morphometric analysis. The simultaneous application of OF + MC was found to be highly effective in terms of the parameters analyzed (P < .05), with positive effects on the area of newly formed tissue, number of fibroblasts, number of newly formed blood vessels, and epithelial thickness. Morphometric data confirmed the structural findings. The O. flexuosum leaf extract contains active compounds that speed the healing process, especially when applied simultaneously with microcurrent stimulation