Low-momentum nucleon-nucleon interaction and its application to few-nucleon systems

Low-momentum nucleon-nucleon interactions are derived within the framework of a unitary-transformationtheory, starting with realistic nucleon-nucleon interactions. A cutoff momentum L is introduced to specify aborder between the low- and high-momentum spaces. By Faddeev-Yakubovsky calculations the lowmomentuminteractions are investigated with respect to the dependence of ground-state energies of 3H and 4Heon the parameter L. It is found that we need the momentum cutoff parameter Lù5 fm−1 in order to reproducesatisfactorily the exact values of the binding energies for 3H and 4He. The calculation with L=2 fm−1 recommendedby Bogner et al. leads to considerable overbinding at least for few-nucleon systems

Low-momentum nucleon-nucleon interaction and its application to few-nucleon systems

Low-momentum nucleon-nucleon interactions are derived within the framework of a unitary-transformation theory, starting with realistic nucleon-nucleon interactions. A cutoff momentum L is introduced to specify a border between the low- and high-momentum spaces. By Faddeev-Yakubovsky calculations the lowmomentum interactions are investigated with respect to the dependence of ground-state energies of 3H and 4He on the parameter L. It is found that we need the momentum cutoff parameter Lù5 fm−1 in order to reproduce satisfactorily the exact values of the binding energies for 3H and 4He. The calculation with L=2 fm−1 recommended by Bogner et al. leads to considerable overbinding at least for few-nucleon systems

Effects of Tongue Pressure on Cerebral Blood Volume Dynamics: A Functional Near-Infrared Spectroscopy Study

Tongue pressure measurement (TPM) is an indicator of oral function. However, the association between tongue pressure and cerebral activation remains unclear. We used near-infrared spectroscopy (NIRS) to examine the correlation between cerebral cortex activation and tongue pressure stimulation against the anterior palatal mucosa. We measured voluntary maximum tongue pressure (MTP) using a TPM device; a pressure value of approximately 60% of the MTP was used for the experimental tongue pressure (MTP60%). We examined the effect of oral functional tongue pressure stimulation against the anterior palatal mucosa on cerebral activation using NIRS in 13 adults. Tongue pressure stimulation caused significant changes in cerebral blood flow in some areas compared with controls (p < 0.05). We performed a correlation analysis (p < 0.05) between MTP60% and changes in oxygenated hemoglobin in all 47 NIRS channels. MTP60% triggered activation of the right somatosensory motor area and right dorsolateral prefrontal cortex and deactivation of the anterior prefrontal cortex (APFC). TPM balloon-probe insertion in the oral cavity activated the bilateral somatosensory motor area and deactivated the wide area of the APFC. Moreover, MTP60% via the TPM balloon probe activated the bilateral somatosensory and motor cortex areas. Tongue pressure stimulation changes cerebral blood flow, and NIRS is useful in investigating the relationship between oral stimulation and brain function

Tumor-Infiltrating CD45RO⁺ Memory Cells Are Associated with Favorable Prognosis in Oral Squamous Cell Carcinoma Patients

Background: Tumor-infiltrating lymphocytes (TILs) have been used to predict the prognosis of solid tumors. In this study, we investigated which molecules in TILs play a role in the prognosis of patients with oral squamous cell carcinoma (OSCC). Methods: In a retrospective case-control study, we immunohistochemically evaluated the expression of CD3, CD8, CD45RO, Granzyme B, and the major histocompatibility complex class I chain-related molecule A (MICA) of the histocompatibility complex as predictors of prognosis in 33 patients with OSCC. The patients were classified as TILsHigh or TILsLow according to the number of TILs for each molecule in the central tumor (CT) and invasive margin (IM). Furthermore, MICA expression scores were determined based on the intensity of the staining. Results: CD45RO+/TIL in the nonrecurrent group were significantly higher than those in the recurrent group in the CT and IM areas (p +/TILsLow group in the CT and IM areas and the Granzyme B+/TILsLow group in the IM area was significantly lower than that of the CD45RO+/TILsHigh group and the Granzyme B+/TILsHigh group, respectively (p +/TILsHigh group was significantly higher than that of the CD45RO+/TILsLow group (p < 0.05). Conclusions: A high ratio of CD45RO-expressing TILs was associated with a disease-free/overall survival improvement in OSCC patients. Furthermore, the number of TILs that express CD45RO was associated with the expression of MICA in tumors. These results suggest that CD45RO-expressing TILs are useful biomarkers for OSCC