724 research outputs found
Ray-based calculations of backscatter in laser fusion targets
A 1D, steady-state model for Brillouin and Raman backscatter from an
inhomogeneous plasma is presented. The daughter plasma waves are treated in the
strong damping limit, and have amplitudes given by the (linear) kinetic
response to the ponderomotive drive. Pump depletion, inverse-bremsstrahlung
damping, bremsstrahlung emission, Thomson scattering off density fluctuations,
and whole-beam focusing are included. The numerical code DEPLETE, which
implements this model, is described. The model is compared with traditional
linear gain calculations, as well as "plane-wave" simulations with the paraxial
propagation code pF3D. Comparisons with Brillouin-scattering experiments at the
OMEGA Laser Facility [T. R. Boehly et al., Opt. Commun. 133, p. 495 (1997)]
show that laser speckles greatly enhance the reflectivity over the DEPLETE
results. An approximate upper bound on this enhancement, motivated by phase
conjugation, is given by doubling the DEPLETE coupling coefficient. Analysis
with DEPLETE of an ignition design for the National Ignition Facility (NIF) [J.
A. Paisner, E. M. Campbell, and W. J. Hogan, Fusion Technol. 26, p. 755
(1994)], with a peak radiation temperature of 285 eV, shows encouragingly low
reflectivity. Re-absorption of Raman light is seen to be significant in this
design.Comment: 16 pages, 19 figure
Resumming the large-N approximation for time evolving quantum systems
In this paper we discuss two methods of resumming the leading and next to
leading order in 1/N diagrams for the quartic O(N) model. These two approaches
have the property that they preserve both boundedness and positivity for
expectation values of operators in our numerical simulations. These
approximations can be understood either in terms of a truncation to the
infinitely coupled Schwinger-Dyson hierarchy of equations, or by choosing a
particular two-particle irreducible vacuum energy graph in the effective action
of the Cornwall-Jackiw-Tomboulis formalism. We confine our discussion to the
case of quantum mechanics where the Lagrangian is . The
key to these approximations is to treat both the propagator and the
propagator on similar footing which leads to a theory whose graphs have the
same topology as QED with the propagator playing the role of the photon.
The bare vertex approximation is obtained by replacing the exact vertex
function by the bare one in the exact Schwinger-Dyson equations for the one and
two point functions. The second approximation, which we call the dynamic Debye
screening approximation, makes the further approximation of replacing the exact
propagator by its value at leading order in the 1/N expansion. These two
approximations are compared with exact numerical simulations for the quantum
roll problem. The bare vertex approximation captures the physics at large and
modest better than the dynamic Debye screening approximation.Comment: 30 pages, 12 figures. The color version of a few figures are
separately liste
Family coordination in families who have a child with autism spectrum disorder
Little is known about the interactions of families where there is a child with autism spectrum disorder (ASD). The present study applies the Lausanne Trilogue Play (LTP) to explore both its applicability to this population as well as to assess resources and areas of deficit in these families. The sample consisted of 68 families with a child with ASD, and 43 families with a typically developing (TD) child. With respect to the global score for family coordination there were several negative correlations: the more severe the symptoms (based on the child’s ADOS score), the more family coordination was dysfunctional. This correlation was particularly high when parents had to play together with the child. In the parts in which only one of the parents played actively with the child, while the other was simply present, some families did achieve scores in the functional range, despite the child’s symptom severity. The outcomes are discussed in terms of their clinical implications both for assessment and for interventio
Markov Properties of Electrical Discharge Current Fluctuations in Plasma
Using the Markovian method, we study the stochastic nature of electrical
discharge current fluctuations in the Helium plasma. Sinusoidal trends are
extracted from the data set by the Fourier-Detrended Fluctuation analysis and
consequently cleaned data is retrieved. We determine the Markov time scale of
the detrended data set by using likelihood analysis. We also estimate the
Kramers-Moyal's coefficients of the discharge current fluctuations and derive
the corresponding Fokker-Planck equation. In addition, the obtained Langevin
equation enables us to reconstruct discharge time series with similar
statistical properties compared with the observed in the experiment. We also
provide an exact decomposition of temporal correlation function by using
Kramers-Moyal's coefficients. We show that for the stationary time series, the
two point temporal correlation function has an exponential decaying behavior
with a characteristic correlation time scale. Our results confirm that, there
is no definite relation between correlation and Markov time scales. However
both of them behave as monotonic increasing function of discharge current
intensity. Finally to complete our analysis, the multifractal behavior of
reconstructed time series using its Keramers-Moyal's coefficients and original
data set are investigated. Extended self similarity analysis demonstrates that
fluctuations in our experimental setup deviates from Kolmogorov (K41) theory
for fully developed turbulence regime.Comment: 25 pages, 9 figures and 4 tables. V3: Added comments, references,
figures and major correction
Ecological Validity of Immersive Virtual Reality (IVR) Techniques for the Perception of Urban Sound Environments
Immersive Virtual Reality (IVR) is a simulated technology used to deliver multisensory information to people under different environmental conditions. When IVR is generally applied in urban planning and soundscape research, it reveals attractive possibilities for the assessment of urban sound environments with higher immersion for human participation. In virtual sound environments, various topics and measures are designed to collect subjective responses from participants under simulated laboratory conditions. Soundscape or noise assessment studies during virtual experiences adopt an evaluation approach similar to in situ methods. This paper aims to review the approaches that are utilized to assess the ecological validity of IVR for the perception of urban sound environments and the necessary technologies during audio–visual reproduction to establish a dynamic IVR experience that ensures ecological validity. The review shows that, through the use of laboratory tests including subjective response surveys, cognitive performance tests and physiological responses, the ecological validity of IVR can be assessed for the perception of urban sound environments. The reproduction system with head-tracking functions synchronizing spatial audio and visual stimuli (e.g., head-mounted displays (HMDs) with first-order Ambisonics (FOA)-tracked binaural playback) represents the prevailing trend to achieve high ecological validity. These studies potentially contribute to the outcomes of a normalized evaluation framework for subjective soundscape and noise assessments in virtual environment
A randomized controlled trial of metformin on left ventricular hypertrophy in patients with coronary artery disease without diabetes:the MET-REMODEL trial
Aim
We tested the hypothesis that metformin may regress left ventricular hypertrophy (LVH) in patients who have coronary artery disease (CAD), with insulin resistance (IR) and/or pre-diabetes.
Methods and results
We randomly assigned 68 patients (mean age 65 ± 8 years) without diabetes who have CAD with IR and/or pre-diabetes to receive either metformin XL (2000 mg daily dose) or placebo for 12 months. Primary endpoint was change in left ventricular mass indexed to height1.7 (LVMI), assessed by magnetic resonance imaging. In the modified intention-to-treat analysis (n = 63), metformin treatment significantly reduced LVMI compared with placebo group (absolute mean difference −1.37 (95% confidence interval: −2.63 to −0.12, P = 0.033). Metformin also significantly reduced other secondary study endpoints such as: LVM (P = 0.032), body weight (P = 0.001), subcutaneous adipose tissue (P = 0.024), office systolic blood pressure (BP, P = 0.022) and concentration of thiobarbituric acid reactive substances, a biomarker for oxidative stress (P = 0.04). The glycated haemoglobin A1C concentration and fasting IR index did not differ between study groups at the end of the study.
Conclusion
Metformin treatment significantly reduced LVMI, LVM, office systolic BP, body weight, and oxidative stress. Although LVH is a good surrogate marker of cardiovascular (CV) outcome, conclusive evidence for the cardio-protective role of metformin is required from large CV outcomes trials
Low Fidelity Imitation of Atypical Biological Kinematics in Autism Spectrum Disorders Is Modulated by Self-Generated Selective Attention.
We examined whether adults with autism had difficulty imitating atypical biological kinematics. To reduce the impact that higher-order processes have on imitation we used a non-human agent model to control social attention, and removed end-state target goals in half of the trials to minimise goal-directed attention. Findings showed that only neurotypical adults imitated atypical biological kinematics. Adults with autism did, however, become significantly more accurate at imitating movement time. This confirmed they engaged in the task, and that sensorimotor adaptation was self-regulated. The attentional bias to movement time suggests the attenuation in imitating kinematics might be a compensatory strategy due to deficits in lower-level visuomotor processes associated with self-other mapping, or selective attention modulated the processes that represent biological kinematics
Genetic and neurological foundations of customer orientation: field and experimental evidence
We explore genetic and neurological bases for customer orientation (CO) and contrast them with sales orientation (SO). Study 1 is a field study that establishes that CO, but not SO, leads to greater opportunity recognition. Study 2 examines genetic bases for CO and finds that salespeople with CO are more likely to have the 7R variant of the DRD4 gene. This is consistent with basic research on dopamine receptor activity in the brain that underlies novelty seeking, the reward function, and risk taking. Study 3 examines the neural basis of CO and finds that salespeople with CO, but not SO, experience greater activation of their mirror neuron systems and neural processes associated with empathy. Managerial and research implications are discussed
State of the climate in 2013
In 2013, the vast majority of the monitored climate variables reported here maintained trends established in recent decades. ENSO was in a neutral state during the entire year, remaining mostly on the cool side of neutral with modest impacts on regional weather patterns around the world. This follows several years dominated by the effects of either La Niña or El Niño events. According to several independent analyses, 2013 was again among the 10 warmest years on record at the global scale, both at the Earths surface and through the troposphere. Some regions in the Southern Hemisphere had record or near-record high temperatures for the year. Australia observed its hottest year on record, while Argentina and New Zealand reported their second and third hottest years, respectively. In Antarctica, Amundsen-Scott South Pole Station reported its highest annual temperature since records began in 1957. At the opposite pole, the Arctic observed its seventh warmest year since records began in the early 20th century. At 20-m depth, record high temperatures were measured at some permafrost stations on the North Slope of Alaska and in the Brooks Range. In the Northern Hemisphere extratropics, anomalous meridional atmospheric circulation occurred throughout much of the year, leading to marked regional extremes of both temperature and precipitation. Cold temperature anomalies during winter across Eurasia were followed by warm spring temperature anomalies, which were linked to a new record low Eurasian snow cover extent in May. Minimum sea ice extent in the Arctic was the sixth lowest since satellite observations began in 1979. Including 2013, all seven lowest extents on record have occurred in the past seven years. Antarctica, on the other hand, had above-average sea ice extent throughout 2013, with 116 days of new daily high extent records, including a new daily maximum sea ice area of 19.57 million km2 reached on 1 October. ENSO-neutral conditions in the eastern central Pacific Ocean and a negative Pacific decadal oscillation pattern in the North Pacific had the largest impacts on the global sea surface temperature in 2013. The North Pacific reached a historic high temperature in 2013 and on balance the globally-averaged sea surface temperature was among the 10 highest on record. Overall, the salt content in nearsurface ocean waters increased while in intermediate waters it decreased. Global mean sea level continued to rise during 2013, on pace with a trend of 3.2 mm yr-1 over the past two decades. A portion of this trend (0.5 mm yr-1) has been attributed to natural variability associated with the Pacific decadal oscillation as well as to ongoing contributions from the melting of glaciers and ice sheets and ocean warming. Global tropical cyclone frequency during 2013 was slightly above average with a total of 94 storms, although the North Atlantic Basin had its quietest hurricane season since 1994. In the Western North Pacific Basin, Super Typhoon Haiyan, the deadliest tropical cyclone of 2013, had 1-minute sustained winds estimated to be 170 kt (87.5 m s-1) on 7 November, the highest wind speed ever assigned to a tropical cyclone. High storm surge was also associated with Haiyan as it made landfall over the central Philippines, an area where sea level is currently at historic highs, increasing by 200 mm since 1970. In the atmosphere, carbon dioxide, methane, and nitrous oxide all continued to increase in 2013. As in previous years, each of these major greenhouse gases once again reached historic high concentrations. In the Arctic, carbon dioxide and methane increased at the same rate as the global increase. These increases are likely due to export from lower latitudes rather than a consequence of increases in Arctic sources, such as thawing permafrost. At Mauna Loa, Hawaii, for the first time since measurements began in 1958, the daily average mixing ratio of carbon dioxide exceeded 400 ppm on 9 May. The state of these variables, along with dozens of others, and the 2013 climate conditions of regions around the world are discussed in further detail in this 24th edition of the State of the Climate series. © 2014, American Meteorological Society. All rights reserved
- …
