WITHDRAWN: A subacute case of traumatic avulsion of the flexor digitorum pofundus tendon due to recurrent enchondroma of the distal phalanx

Abstract Avulsion of the flexor digitorum profundus (FDP) tendon associated to an enchondroma fracture in the distal phalanx is very rare. We report a subacute case of a type II FDP tendon avulsion of the small finger at its insertion, in combination with a fracture of the distal phalanx due to enchondroma. The bone lesion was curated and grafted using autogenous bone harvested from the ipsilateral radius. The FDP tendon was reattached to the distal phalanx using the pullout transosseous technique. Delayed protected active mobilization was used to treat the repaired tendon. According to the adjusted Strickland score, a good result was obtained and grip strength was similar between hands and PRWHE score was very low at 5 months from surgery. Early diagnosis leads to a fast surgery with good functional mobility and pain outcomes. If closely monitored by an experienced medical team, as this case demonstrates, an attempt to treat the benign tumor with a curettage, bone filling and reattachment of the tendon through the pullout technique in young motivated patients can be an alternative

Perfluoropolyethers coatings design for fouling reduction on heat transfer stainless steel surfaces

The scope of this research is to obtain a film coating on stainless steel surfaces in order to reduce the interaction between the metal surface and the precipitates, so to mitigate fouling in heat exchangers. Perfuoropolyethers were used to obtain nano-range fluorinated layers in order to make hydrophobic the stainless steel surfaces. A pilot plant with two identical heat exchangers was built to investigate the ability of the hydrophobic coating of preventing fouling. The heat exchangers, installed in parallel, operated at the same temperature and pressure conditions, i.e. laminar flow regime and inlet flow temperatures of 291\u2013293 K for cold streams and 313\u2013333 K for hot streams. We compared the heat transfer performance of the two heat exchangers. After a five months operation the decrease in the heat transferred was 56% for the coated heat exchanger and 62% for the uncoated heat exchanger. Moreover, the increase of heat transfer resistance due to scale on the uncoated heat exchanger, with respect to the coated one, was three times higher

Computational study of photoexcited dynamics in bichromophoric cross-shaped oligofluorene

The non-adiabatic excited state molecular dynamics (NA-ESMD) approach is applied to investigate photoexcited dynamics and relaxation pathways in a spiro-linked conjugated polyfluorene at room (T = 300 K) and low (T = 10 K) temperatures. This dimeric aggregate consists of two perpendicularly oriented weakly interacting α-polyfluorene oligomers. The negligible coupling between the monomer chains results in an initial absorption band composed of equal contributions of the two lowest excited electronic states, each localized on one of the two chains. After photoexcitation, an efficient ultrafast localization of the entire electronic population to the lowest excited state is observed on the time scale of about 100 fs. Both internal conversion between excited electronic states and vibronic energy relaxation on a single electronic state contribute to this process. Thus, photoexcited dynamics of the polyfluorene dimer follows two distinct pathways with substantial temperature dependence on their efficiency. One relaxation channel involves resonance electronic energy transfer between the monomer chains, whereas the second pathway concerns the relaxation of the electronic energy on the same chain that has been initially excited due to electron-phonon coupling. Despite the slower vibrational relaxation, a more efficient ultrafast electronic relaxation is observed at low temperature. Our numerical simulations analyze the effects of molecular geometry distortion during the electronic energy redistribution and suggest spectroscopic signatures reflecting complex electron-vibrational dynamics.Fil: Ondarse Alvarez, Dianelys. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional de Quilmes; ArgentinaFil: Oldani, Andres Nicolas. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional de Quilmes; ArgentinaFil: Tretiak, S.. Los Alamos National Laboratory. Los Alamos; Estados UnidosFil: Fernández Alberti, Sebastián. Universidad Nacional de Quilmes; Argentin

Aquivion® PFSA-based spray-freeze dried composite materials with SiO2 and TiO2 as hybrid catalysts for the gas phase dehydration of ethanol to ethylene in mild conditions

Aquivion PFSA resin, a perfluorinated ion-exchange polymer, has been used as a heterogeneous strong acid catalyst for a range of reactions; however, the activity of this material is limited due to the extremely low surface area of the polymer. In this paper we described the one-step synthesis of Aquivion® PFSA-based hybrid materials using heterocoagulation and spray-freeze-drying of sols containing the precursor of the active phases. The intimated encapsulation of different nano-oxides, such as TiO2 and SiO2 in the superacid resin matrix was easily obtained using this technique and compared with similar catalysts prepared by the impregnation conventional route. The approach led to the preparation of porous micro-granules characterised by a high homogeneity in the phase distribution and high surface area. The prepared materials were active and selective for the gas phase dehydration of ethanol to ethylene in mild conditions. The increase of the porosity improved the activity of the composites, compared to the pure Aquivion® PFSA, and allowed to reduce the amount of the superacid resin. Moreover, the type of encapsulated oxide, TiO2 or SiO2, modified the improved performance of the catalysts, having TiO2 the higher efficiency for ethanol conversion and selectivity in ethylene at very low temperature

Propagation of hippocampal ripples to the neocortex by way of a subiculum-retrosplenial pathway

Bouts of high frequency activity known as sharp wave ripples (SPW-Rs) facilitate communication between the hippocampus and neocortex. However, the paths and mechanisms by which SPW-Rs broadcast their content are not well understood. Due to its anatomical positioning, the granular retrosplenial cortex (gRSC) may be a bridge for this hippocampo-cortical dialogue. Using silicon probe recordings in awake, head-fixed mice, we show the existence of SPW-R analogues in gRSC and demonstrate their coupling to hippocampal SPW-Rs. gRSC neurons reliably distinguished different subclasses of hippocampal SPW-Rs according to ensemble activity patterns in CA1. We demonstrate that this coupling is brain state-dependent, and delineate a topographically-organized anatomical pathway via VGlut2-expressing, bursty neurons in the subiculum. Optogenetic stimulation or inhibition of bursty subicular cells induced or reduced responses in superficial gRSC, respectively. These results identify a specific path and underlying mechanisms by which the hippocampus can convey neuronal content to the neocortex during SPW-Rs

Electronic Energy Relaxation in a Photoexcited Fully Fused Edge-Sharing Carbon Nanobelt

Carbon nanobelts are cylindrical molecules composed of fully fused edge-sharing arene rings. Because of their aesthetically appealing structures, they acquire unusual optoelectronic properties that are potentially suitable for a range of applications in nanoelectronics and photonics. Nevertheless, the very limited success of their synthesis has led to their photophysical properties remaining largely unknown. Compared to that of carbon nanorings (arenes linked by single bonds), the strong structural rigidity of nanobelts prevents significant deformations away from the original high-symmetry conformation and, therefore, impacts their photophysical properties. Herein, we study the photoinduced dynamics of a successfully synthesized belt segment of (6,6)CNT (carbon nanotube). Modeling this process with nonadiabatic excited state molecular dynamics simulations uncovers the critical role played by the changes in excited state wave function localization on the different types of carbon atoms. This allows a detailed description of the excited state dynamics and spatial exciton evolution throughout the nanobelt scaffold. Our results provide detailed information about the excited state electronic properties and internal conversion rates that is potentially useful for designing nanobelts for nanoelectronic and photonic applications.Fil: Freixas Lemus, Victor Manuel. Universidad Nacional de Quilmes. Departamento de Ciencia y Tecnología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Oldani, Andres Nicolas. Universidad Nacional de Quilmes. Departamento de Ciencia y Tecnología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Franklin Mergarejo, Ricardo. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional de Quilmes. Departamento de Ciencia y Tecnología; ArgentinaFil: Tretiak, S.. Los Alamos National High Magnetic Field Laboratory; Estados UnidosFil: Fernández Alberti, Sebastián. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional de Quilmes. Departamento de Ciencia y Tecnología; Argentin

Reply to: "Pre-retrieval reperfusion decreases cancer recurrence after rat ischemic liver graft transplantation"

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SynaptoPAC, an optogenetic tool for induction of presynaptic plasticity

Optogenetic manipulations have transformed neuroscience in recent years. While sophisticated tools now exist for controlling the firing patterns of neurons, it remains challenging to optogenetically define the plasticity state of individual synapses. A variety of synapses in the mammalian brain express presynaptic long-term potentiation (LTP) upon elevation of presynaptic cyclic adenosine monophosphate (cAMP), but the molecular expression mechanisms as well as the impact of presynaptic LTP on network activity and behavior are not fully understood. In order to establish optogenetic control of presynaptic cAMP levels and thereby presynaptic potentiation, we developed synaptoPAC, a presynaptically targeted version of the photoactivated adenylyl cyclase bPAC. In cultures of hippocampal granule cells, activation of synaptoPAC with blue light increases action potential-evoked transmission, an effect not seen in hippocampal cultures of non-granule cells. In acute brain slices, synaptoPAC activation immediately triggers a strong presynaptic potentiation at mossy fiber terminals in CA3, but not at Schaffer collateral synapse in CA1. Following light-triggered potentiation, mossy fiber transmission decreases within 20 minutes, but remains enhanced still after 30 min. Optogenetic potentiation alters the short-term plasticity dynamics of release, reminiscent of presynaptic LTP. SynaptoPAC is the first optogenetic tool that allows acute light-controlled potentiation of transmitter release at specific synapses of the brain, and will enable to investigate the role of presynaptic potentiation in network function and the animal’s behavior in an unprecedented manner. SIGNIFICANCE STATEMENT: SynaptoPAC is a novel optogenetic tool that allows increasing synaptic transmission by light-controlled induction of presynaptic plasticity

Mechanocatalytic Depolymerization of Cellulose With Perfluorinated Sulfonic Acid Ionomers

Here, we investigated that the mechanocatalytic depolymerization of cellulose in the presence of Aquivion, a sulfonated perfluorinated ionomer. Under optimized conditions, yields of water soluble sugars of 90-97% were obtained using Aquivion PW98 and PW66, respectively, as a solid acid catalyst. The detailed characterization of the water soluble fraction revealed (i) the selective formation of oligosaccharides with a DP up to 11 and (ii) that depolymerization and reversion reactions concomitantly occurred during the mechanocatalytic process, although the first largely predominated. More importantly, we discussed on the critical role of water contained in Aquivion and cellulose on the efficiency of the mechanocatalytic process.CNRS Centre National de la Recherche ScientifiqueUniversity of PoitiersSpanish Ministerio de Economía y Competitividad (MINECO, CTQ2015-64425-C2-1-R)Junta de Andalucía ( FQM2012-1467

Comet Machholz (C/2004 Q2): morphological structures in the inner coma and rotation parameters

Extensive observations of comet C/2004 Q2 (Machholz) were carried out between August 2004 and May 2005. The images obtained were used to investigate the comet's inner coma features at resolutions between 350 and 1500 km/pixel. A photometric analysis of the dust outflowing from the comet's nucleus and the study of the motion of the morphological structures in the inner coma indicated that the rotation period of the nucleus was most likely around 0.74 days. A thorough investigation of the inner coma morphology allowed us to observe two main active sources on the comet's nucleus, at a latitude of +85{\deg} \pm 5{\deg} and +45{\deg} \pm 5{\deg}, respectively. Further sources have been observed, but their activity ran out quite rapidly over time; the most relevant was at latcom. = 25{\deg} \pm 5{\deg}. Graphic simulations of the geometrical conditions of observation of the inner coma were compared with the images and used to determine a pole orientation at RA=95{\deg} \pm 5{\deg}, Dec=+35{\deg} \pm 5{\deg}. The comet's spin axis was lying nearly on the plane of the sky during the first decade of December 2004.Comment: 29 pages, 8 figures, 3 table