3,029 research outputs found
Current Standards in the Management of Cerebral Metastases
The last 30 years have seen major changes in attitude toward patients with cerebral metastases. This paper aims to outline the major landmarks in this transition and the therapeutic strategies currently used. The controversies surrounding control of brain disease are discussed, and two emerging management trends are reviewed: tumor bed radiosurgery and salvage radiation
Decreasing Cerebral Oxygen Consumption During Upright Tilt in Vasovagal Syncope
We measured changes in transcranial Doppler ultrasound (TCD) and near infrared spectroscopy (NIRS) during 70 degrees upright tilt in patients with recurrent vasovagal syncope (VVS, N = 20), postural tachycardia syndrome (POTS, N = 20), and healthy controls (N = 12) aged 15-27 years old. VVS was included if they fainted during testing within 5-15 min of upright tilt. We combined TCD and NIRS to obtain estimates of percent change in the cerebral metabolic rate of oxygen consumption (CMRO2), cerebral blood flow velocity (CBFv), and oxygen extraction fraction (OEF). Over the course of 10 min of upright tilt, CBFv decreased from a baseline of 70 +/- 5 to 63 +/- 5 cm/sec in controls and 74 +/- 3 to 64 +/- 3 cm/sec in POTS while decreasing from 74 +/- 4 to 44 +/- 3 cm/sec in VVS CMRO2 was unchanged in POTS and controls during tilt while OEF increased by 19 +/- 3% and 15 +/- 3%, respectively. CMRO2 decreased by 31 +/- 3% in VVS during tilt while OEF only increased by 7 +/- 3%. Oxyhemoglobin decreased by 1.1 +/- 1.3 mumol/kg brain tissue in controls, by 1.1 +/- 1.3 mumol/kg in POTS, and 11.1 +/- 1.3 mumol/kg in VVS CBFv and CMRO2 fell steadily in VVS during upright tilt. The deficit in CMRO2 in VVS results from inadequate OEF in the face of greatly reduced CBF
The Effect of Thermal Fluctuations on Schulman Area Elasticity
We study the elastic properties of a two-dimensional fluctuating surface
whose area density is allowed to deviate from its optimal (Schulman) value. The
behavior of such a surface is determined by an interplay between the
area-dependent elastic energy, the curvature elasticity, and the entropy. We
identify three different elastic regimes depending on the ratio
between the projected (frame) and the saturated areas. We show that thermal
fluctuations modify the elastic energy of stretched surfaces (),
and dominate the elastic energy of compressed surfaces (). When
the elastic energy is not much affected by the fluctuations; the
frame area at which the surface tension vanishes becomes smaller than and
the area elasticity modulus increases.Comment: 12 pages, to appear in Euro. Phys. J.
Comparison of methods for calibrating AVIRIS data to ground reflectance
We are comparing three basic methods of calibrating AVIRIS data to ground reflectance: (1) atmospheric radiative transfer models with the solar flux can be used to calibrate AVIRIS radiance data (Specific methods include the University of Colorado CSES ARP and ATREM algorithms); (2) Robert Green's modified MODTRAN and AVIRIS radiance model (This method is similar to 1 but differs in that the solar radiance is bypassed, so any errors in the solar flux are canceled, too); and (3) ground calibration using known sites in the AVIRIS scene. We are using 1992AVIRIS data over Cuprite, Nevada, and Blackhawk Island, Wisconsin, as our test scenes. Both these sites have extensive field measurements. The Cuprite site had a very clear atmosphere, thus path radiance was dominated by Rayleigh scattering with little or no flux beyond 1 micron. The Blackhawk site has more aerosols, with significant path radiance flux beyond 2 micron
P33. Expression of alpha v beta 3 integrin in patients with high and low grade glioma
Fuente Fuente, Carlos;Puig-Pey, J.;Buenaño Pastor, Manue
Spitzer, Near-Infrared, and Submillimeter Imaging of the Relatively Sparse Young Cluster, Lynds 988e
We present {\it Spitzer} images of the relatively sparse, low luminosity
young cluster L988e, as well as complementary near-infrared (NIR) and
submillimeter images of the region. The cluster is asymmetric, with the western
region of the cluster embedded within the molecular cloud, and the slightly
less dense eastern region to the east of, and on the edge of, the molecular
cloud. With these data, as well as with extant H data of stars
primarily found in the eastern region of the cluster, and a molecular CO
gas emission map of the entire region, we investigate the distribution of
forming young stars with respect to the cloud material, concentrating
particularly on the differences and similarities between the exposed and
embedded regions of the cluster. We also compare star formation in this region
to that in denser, more luminous and more massive clusters already investigated
in our comprehensive multi-wavelength study of young clusters within 1 kpc of
the Sun.Comment: 21 pages, 6 tables, 13 figures. Full resolution figures at:
http://astro.pas.rochester.edu/~tom/Preprints/L988e.pd
Self-gravitating domain walls and the thin-wall limit
We analyse the distributional thin wall limit of self gravitating scalar
field configurations representing thick domain wall geometries. We show that
thick wall solutions can be generated by appropiate scaling of the thin wall
ones, and obtain an exact solution for a domain wall that interpolates between
AdS_4 asymptotic vacua and has a well-defined thin wall limit.Solutions
representing scalar field configurations obtained via the same scaling but that
do not have a thin wall limit are also presented.Comment: 10 pages, revte
Phase ordering and shape deformation of two-phase membranes
Within a coupled-field Ginzburg-Landau model we study analytically phase
separation and accompanying shape deformation on a two-phase elastic membrane
in simple geometries such as cylinders, spheres and tori. Using an exact
periodic domain wall solution we solve for the shape and phase ordering field,
and estimate the degree of deformation of the membrane. The results are
pertinent to a preferential phase separation in regions of differing curvature
on a variety of vesicles.Comment: 4 pages, submitted to PR
An all-sky search algorithm for continuous gravitational waves from spinning neutron stars in binary systems
Rapidly spinning neutron stars with non-axisymmetric mass distributions are
expected to generate quasi-monochromatic continuous gravitational waves. While
many searches for unknown, isolated spinning neutron stars have been carried
out, there have been no previous searches for unknown sources in binary
systems. Since current search methods for unknown, isolated neutron stars are
already computationally limited, expanding the parameter space searched to
include binary systems is a formidable challenge. We present a new hierarchical
binary search method called TwoSpect, which exploits the periodic orbital
modulations of the continuous waves by searching for patterns in doubly
Fourier-transformed data. We will describe the TwoSpect search pipeline,
including its mitigation of detector noise variations and corrections for
Doppler frequency modulation caused by changing detector velocity. Tests on
Gaussian noise and on a set of simulated signals will be presented.Comment: 22 pages, 10 figures, 1 table, Submitted to Classical and Quantum
Gravit
Low-Temperature Phase Transitions in a Soluble Oligoacene and Their Effect on Device Performance and Stability
The use of organic semiconductors in high-performance organic field-effect transistors requires a thorough understanding of the effects that processing conditions, thermal, and bias-stress history have on device operation. Here, we evaluate the temperature dependence of the electrical properties of transistors fabricated with 2,8-difluoro-5,11-bis(triethylsilylethynyl)anthradithiophene, a material that has attracted much attention recently due to its exceptional electrical properties. We have discovered a phase transition at T = 205 K and discuss its implications on device performance and stability. We examined the impact of this low-temperature phase transition on the thermodynamic, electrical, and structural properties of both single crystals and thin films of this material. Our results show that while the changes to the crystal structure are reversible, the induced thermal stress yields irreversible degradation of the devices
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