Faculty Development: Mission and Methods for Practical Integration

This essay proposes a Catholic structure for the intellectual life of faculty that invites participation in ways that honor their diverse backgrounds, even antipathy toward religion, while also demonstrating that identifiable Catholic perspectives, including Catholic social teaching, can provide a useful framework for faculty members to understand their academic roles in support of Catholic identity, no matter their religious background

Robust, gapped, flat bands at half-filling in the minimal model of the superconducting metal-organic framework, Cu-BHT

The superconducting metal-organic framework Cu-BHT forms a kagome lattice with metals at the vertices and ligands along the bonds. We show that a tight-binding model with metal and ligand sites on this lattice yields five flat topological bands (FTBs), three of which are partially occupied at half-filling, with large gaps between them and all other bands. Long-range hopping induces curvature in the FTBs but leaves them flatter and more isolated than those in twisted bilayer graphene. Thus, framework materials are ideal materials for exploring flat band physics at high electronic densities.Comment: 5 pages, 3 figure

Factors Related to the Selection of a Real Estate Agency or Agent

Real estate firms attempting to maintain or increase their market share want to know the characteristics of the firm or individual agents that are important to market participants. A survey of homeowners conducted during August 1987 found the following: 1) the individual agent is more important than the firm itself in the selection of a real estate firm; 2) knowing an agent of the firm was the primary factor considered in the selection of a real estate firm; and 3) agent characteristics of selling ability, competence, integrity, knowledge of the market, and understanding the client's needs and concerns were most important.

Salvageability of renal function following renal revascularisation in children with Takayasu’s arteritis-induced renal artery stenosis

Background. Renal artery revascularisation procedures are usually carried out on children with renal artery stenosis from varied causes, including Takayasu’s   arteritis. Reports on the outcome of such procedures in children usually refer to the improvement in blood pressure, with only minimal mention of effects on renal  function.Objective. Salvageability renal function in children who underw ent renal  revascularisation for Takayasu’s arteritis-induced renal artery stenosis (TARAS) was the focus of this study.Methods. We undertook a retrospective analysis of children aged ≤16 years with angiographically confirmed TARAS who underwent renal artery revascularisation procedures between 1990 and 2010. Outcomes of renal function were studied over a period of 2 years and were defined as: (i) improvement: >20% increase in estimated glomerular filtration rate (e-GFR) from presurgery value; (ii) stabilisation: e-GFR within 20% of presurgery value; and (iii) failure: >20% deterioration in e-GFR from presurgery value. The GFR was estimated using the Schwartz formula.Results. Twenty children (9 males and 11 females, age range 2 - 14 years) had 27 renal artery revascularisation procedures. Thirteen of the patients (65.0%) had bilateral renal artery stenosis. The baseline mean e-GFR was 88.6 (standard deviation (SD) 25.4) mL/min/1.73 m2 and the mean duration of follow-up was 28.80 (SD 25.62) months. All the patients had stable or improved renal function until the 2-year follow-up, when the proportion decreased to 92.3% (12/13), as failure was recorded in one child. Bilateral revascularisation was found to be significantly associated with improvement in renal function in the early postoperative period  (p=0.04).Conclusion. Renal artery revascularisation procedures are successful in salvaging renal function in children with TARA

Photonic quantum signatures of chaos and boson sampling

Boson sampling is a paradigmatic example of a task that can be performed by a quantum photonic computer yet is hard for digital classical computers. In a typical boson sampling experiment, the scattering amplitude is determined by the permanent of a submatrix of a unitary drawn from an ensemble of random matrices. Random matrix theory plays a very important role in quite diverse fields while at the same time being intimately related to quantum signatures of chaos. Within this framework, a chaotic quantum system exhibits level statistics characteristic of ensembles of random matrices. Such quantum signatures are encoded in the unitary evolution and so in this work we combine the dynamics of chaotic systems with boson sampling. One of the key results of our work is that we demonstrate the intimate relation between out-of-time-order correlators and boson sampling. We show that the unitary dynamics of a Floquet system may be exploited to perform sampling tasks with identical particles using single-mode phase shifters and multiport beamsplitters. At the end of our paper propose a photonic implementation of the multiparticle kicked rotor, which provides a concrete example of our general approach.Comment: 17 pages, 7 figures. Comments are welcom

Important HIV-associated conditions in HIV-infected infants and children

This article is the last in a series of 6 articles that discussed the management of HIV-infected children in a clinically orientated, practical and concise fashion. The topics covered previously include; 1) Preventing and diagnosing HIV-infection in infants and children, 2) Initiating anti-retroviral therapy in HIV-infected infants and children, 3) Maintaining HIV-infected infants and children on anti-retroviral therapy, 4) Common opportunistic infection in HIV-infected children: Part 1-respiratory infections and 5) Part 2 non-respiratory infections. South African Family Practice Vol. 49 (4) 2007: pp.19-2

Electron microscopy structure of human APC/C-CDH1-EMI1 reveals multimodal mechanism of E3 ligase shutdown.

The anaphase-promoting complex/cyclosome (APC/C) is a similar to 1.5-MDa multiprotein E3 ligase enzyme that regulates cell division by promoting timely ubiquitin-mediated proteolysis of key cell-cycle regulatory proteins. Inhibition of human APC/C-CDH1 during interphase by early mitotic inhibitor 1 (EMI1) is essential for accurate coordination of DNA synthesis and mitosis. Here, we report a hybrid structural approach involving NMR, electron microscopy and enzymology, which reveal that EMI1's 143-residue C-terminal domain inhibits multiple APC/C-CDH1 functions. The intrinsically disordered D-box, linker and tail elements, together with a structured zinc-binding domain, bind distinct regions of APC/C-CDH1 to synergistically both block the substrate-binding site and inhibit ubiquitin-chain elongation. The functional importance of intrinsic structural disorder is explained by enabling a small inhibitory domain to bind multiple sites to shut down various functions of a 'molecular machine' nearly 100 times its size