Health-related quality of life in the WA HIV Cohort: 2008

Quality of life (QOL) is an important outcome of HIV treatment and a priority in the management of HIV. A new Patient-Reported Outcomes (PRO) questionnaire to measure the QOL in people living with HIV/AIDS (PLWHA) from different cultures and language groups has been developed. The instrument, PROQOL-HIV, has undergone psychometric validation in 791 individuals from 8 countries including 99 people from the WA HIV Cohort Study

A point mass in an isotropic universe: III. The region R≤2mR\leq 2m

McVittie's solution of Einstein's field equations, representing a point mass embedded into an isotropic universe, possesses a scalar curvature singularity at proper radius $R=2m$. The singularity is space-like and precedes, in the expanding case, all other events in the space-time. It is shown here that this singularity is gravitationally weak, and the possible structure of the region $R\leq 2m$ is investigated. A characterization of this solution which does not involve asymptotics is given.Comment: Revtex, 11pp. To appear in Class.Quant.Grav. Paper II appeared as Class. Quant. Grav. 16 (1999) 122

Prospective genetic screening decreases the incidence of Abacavir hypersensitivity reactions in the Western Australian HIV cohort study

Abacavir therapy is associated with significant drug hypersensitivity in ∼8% of recipients, with retrospective studies indicating a strong genetic association with the HLA-B*5701 allelle. In this prospective study, involving 260 abacavir-naive individuals (7.7% of whom were positive for HLA-B*5701), we confirm the usefulness of genetic risk stratification, with no cases of abacavir hypersensitivity among 148 HLA-B*5701–negative recipients

Association between low 25(OH) vitamin D levels, antiretroviral therapy and metabolic profile in a cohort of treated ahd therapy naive HIV positive patients in Western Australia

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Validation of the exercise self-efficacy scale (ESE-S) for increased adherence to physical activity

Background: Various self-efficacy instruments have been used to predict exercise behavior. Many of these scales have been shown tobe valid and reliable measures for the strength dimension of self-efficacy, but have overlooked the construct’s dimensions of magnitude and generality. This study established the Exercise Self-Efficacy Scale (ESE-S), a measure of the strength, generality, and magnitude dimensions of exercise self-efficacy, as a valid tool towards the promotion and adherence of routine physical activity.Methods: Using a non-experimental, cross-sectional design, the ESE-S was administered to individuals aged 18 and older (n=270) whowere conveniently recruited from a large city located in Ohio. Participants were employees of a large, national company and consentedto participate in an employee wellness campaign over a two-day period. Participants completed the 24-item ESE-S onetime and demographic data were not collected. Confirmatory factor analysis was used to examine the 4-factor hypothesized structure of the ESE-S.Results: The confirmatory analysis showed that the data did not conform to the factorial structure as originally hypothesized, but didretain a 4-four factor solution. Final factors identified from the confirmatory analysis were internal strength, external strength, generality, and magnitude.Conclusions: This study confirmed a 4-factor, 21-item factorial structure. Although the structure differed from that hypothesized, theresults showed that the tool was a valid and reliable instrument to measure the dimensions of exercise self-efficacy commonly overlooked within the literature. Public health professionals and researchers can use the instrument to measure exercise self-efficacy and develop self-efficacy based exercise promotion programs

Chasing the second gamma-ray bright isolated neutron star: 3EG J1835+5918/RX J1836.2+5925

The EGRET telescope aboard NASAs Compton GRO has repeatedly detected 3EG J1835+5918, a bright and steady source of high-energy gamma-ray emission with no identification suggested until recently. The long absence of any likely counterpart for a bright gamma-ray source located 25 degrees off the Galactic plane initiated several attempts of deep observations at other wavelengths. We report on counterparts in X-rays on a basis of a 60 ksec ROSAT HRI image. In order to conclude on the plausibility of the X-ray counterparts, we reanalyzed data from EGRET at energies above 100 MeV and above 1 GeV, including data up to CGRO observation cycle 7. The gamma-ray source location represents the latest and probably the final positional assessment based on EGRET data. The X-ray counterparts were studied during follow-up optical identification campaigns, leaving only one object to be likely associated with the gamma-ray source 3EG J1835+5918. This object, RX J1836.2+5925, has the characteristics of an isolated neutron star and possibly of a radio-quiet pulsar.Comment: 5 pages, 3 figures. To appear in the Proceedings of the 270. WE-Heraeus Seminar on Neutron Stars, Pulsars and Supernova Remnants, Jan. 21-25, 2002, Physikzentrum Bad Honnef, eds W. Becker, H. Lesch & J. Truemper. Proceedings are available as MPE-Report 27

Bulk and surface energetics of lithium hydride crystal: benchmarks from quantum Monte Carlo and quantum chemistry

We show how accurate benchmark values of the surface formation energy of crystalline lithium hydride can be computed by the complementary techniques of quantum Monte Carlo (QMC) and wavefunction-based molecular quantum chemistry. To demonstrate the high accuracy of the QMC techniques, we present a detailed study of the energetics of the bulk LiH crystal, using both pseudopotential and all-electron approaches. We show that the equilibrium lattice parameter agrees with experiment to within 0.03 %, which is around the experimental uncertainty, and the cohesive energy agrees to within around 10 meV per formula unit. QMC in periodic slab geometry is used to compute the formation energy of the LiH (001) surface, and we show that the value can be accurately converged with respect to slab thickness and other technical parameters. The quantum chemistry calculations build on the recently developed hierarchical scheme for computing the correlation energy of a crystal to high precision. We show that the hierarchical scheme allows the accurate calculation of the surface formation energy, and we present results that are well converged with respect to basis set and with respect to the level of correlation treatment. The QMC and hierarchical results for the surface formation energy agree to within about 1 %.Comment: 16 pages, 4 figure

Taxing Corporate Distributions of Appreciated Property: Repeal of General Utilities Doctrine, Releif Measures and Entity Reclassification Proposals

Professor Wolfman presents the case for outright repeal of General Utilities and its statutory offspring. Professor Wolfman traces the history of the doctrine and its procedural infirmities, and then describes how several Code sections may be eliminated or simplified. Mr. Nolan argues against the repeal of General Utilities where there is a sale or distribution of assets in complete liquidation, and further argues that the current taxation regime fosters the important social and economic policies that Congress has adopted. Mr. Hobbett discusses the reasons given for entity reclassification, and suggests that preservation of partnership status for publicly traded partnerships would offer an opportunity to experiment with full integration treatment for entities that might resemble corporations. Mr. Hobbett concludes that, if General Utilities were repealed, taxpayers would choose the partnership as an appropriate full integration system