599 research outputs found

    A check list of fishes of the Exclusive Economic Zone of India collected during the research cruises of FORV Sagar Sampada

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    A knowledge on the fish fauna of the Exclusive Economic Zone of India is essential to study the distribution, zoogeography and biological aspects of the fish resources. The present check list of fishes is based on the pelagic and bottom trawl collections of FORV Sagar Sampada during her cruises 1-30, in the EEZ along both the east and west coasts of India during the years 1985-'87. This list is arranged alphabetically by families and genera. The list consists of 87 families and 242 species, including both conventional and nonconventional fish fauna of the Indian EEZ. The depth-wise distribution of the species in the latitude zones are also given

    Transcriptional networks specifying homeostatic and inflammatory programs of gene expression in human aortic endothelial cells.

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    Endothelial cells (ECs) are critical determinants of vascular homeostasis and inflammation, but transcriptional mechanisms specifying their identities and functional states remain poorly understood. Here, we report a genome-wide assessment of regulatory landscapes of primary human aortic endothelial cells (HAECs) under basal and activated conditions, enabling inference of transcription factor networks that direct homeostatic and pro-inflammatory programs. We demonstrate that 43% of detected enhancers are EC-specific and contain SNPs associated to cardiovascular disease and hypertension. We provide evidence that AP1, ETS, and GATA transcription factors play key roles in HAEC transcription by co-binding enhancers associated with EC-specific genes. We further demonstrate that exposure of HAECs to oxidized phospholipids or pro-inflammatory cytokines results in signal-specific alterations in enhancer landscapes and associate with coordinated binding of CEBPD, IRF1, and NFκB. Collectively, these findings identify cis-regulatory elements and corresponding trans-acting factors that contribute to EC identity and their specific responses to pro-inflammatory stimuli

    Financial Impact of Emergency Department Crowding

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    Objective: The economic benefits of reducing emergency department (ED) crowding are potentially substantial as they may decrease hospital length of stay. Hospital administrators and public officials may therefore be motivated to implement crowding protocols. We sought to identify a potential cost of ED crowding by evaluating the contribution of excess ED length of stay (LOS) to overall hospital length of stay. Methods: We performed a retrospective review of administrative data of adult patients from two urban hospitals (one county and one university) in Brooklyn, New York from 2006-2007. Data was provided by each facility. Extrapolating from prior research (Krochmal and Riley, 2005), we determined the increase in total hospital LOS due to extended ED lengths of stay, and applied cost and charge analyses for the two separate facilities. Results: We determined that 6,205 (5.0%) admitted adult patients from the county facility and 3,017 (3.4%) patients from the university facility were held in the ED greater than one day over a one-year period. From prior research, it has been estimated that each of these patient’s total hospital length of stay was increased on average by 11.7% (0.61 days at the county facility, and 0.71 days at the university facility). The increased charges over one year at the county facility due to the extended ED LOS was therefore approximately 9.8million,whiletheincreasedcostsattheuniversityfacilitywereapproximately9.8 million, while the increased costs at the university facility were approximately 3.9 million. Conclusion: Based on extrapolations from Krochmal and Riley applied to two New York urban hospitals, the county hospital could potentially save 9.8millioninchargesandtheuniversityhospital9.8 million in charges and the university hospital 3.9 million in costs per year if they eliminate ED boarding of adult admitted patients by improving movement to the inpatient setting. [West J Emerg Med. 2011;12(2):192-197.

    Kajian Teknis dan Ekonomis Bunkering LNG untuk Pemenuhan Bahan Bakar Gas Kapal Pelni

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    Penggunaan bahan bakar gas pada bidang perkapalan merupakan suatu keuntungan karena dapat menghemat biaya operasi dan mengurangi emisi gas buang. Pemanfaatan gas juga sesuai dengan tujuan pemerintah yang terdapat pada PP No.55/2009 tentang alokasi produksi gas dalam negeri untuk penggunaan lokal sebesar 25%. Proses pengisian bahan bakar (bunkering) LNG pada umumnya dapat dilakukan dengan tiga skema yaitu ship to ship, truck to ship dan onshore to ship. Untuk itu perlu dilakukan kajian untuk menentukan lokasi dan skema bunkering LNG yang akan digunakan pada studi kasus kali ini, yaitu untuk armada kapal PT. Pelni. Penentuan lokasi bunkering dilakukan dengan memperhatikan frekuensi kedatangan dan kebutuhan bunkering LNG pada setiap pelabuhan. Konversi kebutuhan bahan bakar minyak menjadi bahan bakar gas memakai asumsi bahwa motor diesel dimodifikasi menjadi duel fuel engine menggunakan konverter yang dapat dioperasikan dengan rasio bahan bakar HSD dengan LNG sebesar 50:50. Dari hasil didapatkan pada skenario I adalah Jakarta, Surabaya, Balikpapan, Makassar, Ambon dan Sorong. Skenario II dengan penambahan Bau-bau dan Skenario III dengan penambahan Jayapura. Untuk skema bunkering yang akan dipilih ditentukan dengan menggunakan metode Analytical Hierarchy Process (AHP) dengan kriteria yang dipakai diantaranya teknis, keselamatan dan biaya. Dari hasil pembobotan yang terpilih adalah skema truck to ship. Studi ditutup dengan kajian ekonomi dari sisi penyedia LNG dan dari sisi pemilik kapal. Beberapa parameter yang dipakai adalah Net Present Value, Internal Rate Return, dan Payback Period

    An Overview of State Criteria for Declaring a Public Health Emergency

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    https://digitalcommons.unmc.edu/coph_policy_reports/1006/thumbnail.jp

    Analysis of generalized negative binomial distributions attached to hyperbolic Landau levels

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    To each hyperbolic Landau level of the Poincar\'e disc is attached a generalized negative binomial distribution. In this paper, we compute the moment generating function of this distribution and supply its decomposition as a perturbation of the negative binomial distribution by a finitely-supported measure. Using the Mandel parameter, we also discuss the nonclassical nature of the associated coherent states. Next, we determine the L\'evy-Kintchine decomposition its characteristic function when the latter does not vanish and deduce that it is quasi-infinitely divisible except for the lowest hyperbolic Landau level corresponding to the negative binomial distribution. By considering the total variation of the obtained quasi-L\'evy measure, we introduce a new infinitely-divisible distribution for which we derive the characteristic function
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