1,401 research outputs found
Matching the termination of radiating non-uniform transmission-lines
In this contribution a concept of matching the termination of radiating non-uniform transmission-lines is proposed. Using Transmission-Line Super Theory, position and frequency dependent line parameters can be obtained. Therefore, a characteristic impedance can be determined which is also position and frequency dependent. For a single wire transmission-line it could be shown that the maximum value of that characteristic impedance is an optimal termination in the sense of minimizing the variation of the current on the line. This indicates that matching is not a local effect at the position of the concentrated load but a cooperative process including the whole non-uniform transmission-line. In addition this choice of termination minimizes the variation of the radiated power over frequency
Incomplete reversibility of estimated glomerular filtration rate decline following tenofovir disoproxil fumarate exposure.
BACKGROUND: Tenofovir disoproxil fumarate (TDF) has been linked to renal impairment, but the extent to which this impairment is reversible is unclear. We aimed to investigate the reversibility of renal decline during TDF therapy.
METHODS: Cox proportional hazards models assessed factors associated with discontinuing TDF in those with an exposure duration of >6 months. In those who discontinued TDF therapy, linear piecewise regression models estimated glomerular filtration rate (eGFR) slopes before initiation of, during, and after discontinuation of TDF therapy. Factors associated with not achieving eGFR recovery 6 months after discontinuing TDF were assessed using multivariable logistic regression.
RESULTS: We observed declines in the eGFR during TDF exposure (mean slopes, -15.7 mL/minute/1.73 m(2)/year [95% confidence interval {CI}, -20.5 to -10.9] during the first 3 months and -3.1 mL/minute/1.73 m(2)/year [95% CI, -4.6 to -1.7] thereafter) and evidence of eGFR increases following discontinuation of TDF therapy (mean slopes, 12.5 mL/minute/1.73 m(2)/year [95% CI, 8.9-16.1] during the first 3 months and 0.8 mL/minute/1.73 m(2)/year [95% CI,.1-1.5] thereafter). Following TDF discontinuation, 38.6% of patients with a decline in the eGFR did not experience recovery. A higher eGFR at baseline, a lower eGFR after discontinuation of TDF therapy, and more-prolonged exposure to TDF were associated with an increased risk of incomplete recovery 6 months after discontinuation of TDF therapy.
CONCLUSIONS: This study shows that a decline in the eGFR during TDF therapy was not fully reversible in one third of patients and suggests that prolonged TDF exposure at a low eGFR should be avoided
Axial Torsion-Dirac spin Effect in Rotating Frame with Relativistic Factor
In the framework of spacetime with torsion and without curvature, the Dirac
particle spin precession in the rotational system is studied. We write out the
equivalent tetrad of rotating frame, in the polar coordinate system, through
considering the relativistic factor, and the resultant equivalent metric is a
flat Minkowski one. The obtained rotation-spin coupling formula can be applied
to the high speed rotating case, which is consistent with the expectation.Comment: 6 page
Gravitational Lorentz Force and the Description of the Gravitational Interaction
In the context of a gauge theory for the translation group, we have obtained,
for a spinless particle, a gravitational analog of the Lorentz force. Then, we
have shown that this force equation can be rewritten in terms of magnitudes
related to either the teleparallel or the riemannian structures induced in
spacetime by the presence of the gravitational field. In the first case, it
gives a force equation, with torsion playing the role of force. In the second,
it gives the usual geodesic equation of General Relativity. The main conclusion
is that scalar matter is able to feel anyone of the above spacetime geometries,
the teleparallel and the metric ones. Furthermore, both descriptions are found
to be completely equivalent in the sense that they give the same physical
trajectory for a spinless particle in a gravitational field.Comment: Equations (44)-(47) correcte
Multi-transmission-line-beam interactive system
We construct here a Lagrangian field formulation for a system consisting of
an electron beam interacting with a slow-wave structure modeled by a possibly
non-uniform multiple transmission line (MTL). In the case of a single line we
recover the linear model of a traveling wave tube (TWT) due to J.R. Pierce.
Since a properly chosen MTL can approximate a real waveguide structure with any
desired accuracy, the proposed model can be used in particular for design
optimization. Furthermore, the Lagrangian formulation provides for: (i) a clear
identification of the mathematical source of amplification, (ii) exact
expressions for the conserved energy and its flux distributions obtained from
the Noether theorem. In the case of uniform MTLs we carry out an exhaustive
analysis of eigenmodes and find sharp conditions on the parameters of the
system to provide for amplifying regimes
High prevalence of albuminuria amongst people who inject drugs: A cross-sectional study.
Albuminuria is a key biomarker for cardiovascular disease and chronic kidney disease. Our study aimed to describe the prevalence of albuminuria amongst people who inject drugs in London and to test any potential associations with demographic characteristics, past diagnoses, and drug preparation and administration practices. We carried out a cross-sectional survey amongst people who use drugs in London. The main outcome measure was any albuminuria including both microalbuminuria and macroalbuminuria. Three-hundred and sixteen samples were tested by local laboratory services. Our study initially employed point-of-care testing methods but this resulted in a high number of false positives. Our findings suggest the prevalence of albuminuria amongst PWID is twice that of the general population at 19% (95%CI 15.3-24.0%). Risk factors associated with albuminuria were HIV (aOR 4.11 [95% CI 1.37-12.38]); followed by overuse of acidifier for dissolving brown heroin prior to injection (aOR 2.10 [95% CI 1.04-4.22]). Albuminuria is high amongst people who inject drugs compared to the general population suggesting the presence of increased cardiovascular and renal pathologies. This is the first study to demonstrate an association with acidifier overuse. Dehydration may be common amongst this population and may affect the diagnostic accuracy of point-of-care testing for albuminuria
Application of Hansch’s Model to Capsaicinoids and Capsinoids: A Study Using the Quantitative Structure−Activity Relationship. A Novel Method for the Synthesis of Capsinoids
We describe a synthetic approach for two families of compounds, the capsaicinoids and capsinoids,
as part of a study of the quantitative relationship between structure and activity
Torsion Gravity: a Reappraisal
The role played by torsion in gravitation is critically reviewed. After a
description of the problems and controversies involving the physics of torsion,
a comprehensive presentation of the teleparallel equivalent of general
relativity is made. According to this theory, curvature and torsion are
alternative ways of describing the gravitational field, and consequently
related to the same degrees of freedom of gravity. However, more general
gravity theories, like for example Einstein-Cartan and gauge theories for the
Poincare and the affine groups, consider curvature and torsion as representing
independent degrees of freedom. By using an active version of the strong
equivalence principle, a possible solution to this conceptual question is
reviewed. This solution favors ultimately the teleparallel point of view, and
consequently the completeness of general relativity. A discussion of the
consequences for gravitation is presented.Comment: RevTeX, 34 pages. Review article to be published by Int. J. Mod.
Phys.
- …