The mysterious orphans of Mycoplasmataceae

Background: The length of a protein sequence is largely determined by its function, i.e. each functional group is associated with an optimal size. However, comparative genomics revealed that proteins length may be affected by additional factors. In 2002 it was shown that in bacterium Escherichia coli and the archaeon Archaeoglobus fulgidus, protein sequences with no homologs are, on average, shorter than those with homologs. Most experts now agree that the length distributions are distinctly different between protein sequences with and without homologs in bacterial and archaeal genomes. In this study, we examine this postulate by a comprehensive analysis of all annotated prokaryotic genomes and focusing on certain exceptions. Results: We compared lengths distributions of having homologs proteins (HHPs) and non-having homologs proteins (orphans or ORFans) in all currently annotated completely sequenced prokaryotic genomes. As expected, the HHPs and ORFans have strikingly different length distributions in almost all genomes. As previously established, the HHPs, indeed, are, on average, longer than the ORFans, and the length distributions for the ORFans have a relatively narrow peak, in contrast to the HHPs, whose lengths spread over a wider range of values. However, about thirty genomes do not obey these rules. Practically all genomes of Mycoplasma and Ureaplasma have atypical ORFans distributions, with the mean lengths of ORFan larger than the mean lengths of HHPs. These genera constitute over 80% of atypical genomes. Conclusions: We confirmed on a ubiquitous set of genomes the previous observation that HHPs and ORFans have different gene length distributions. We also showed that Mycoplasmataceae genomes have distinctive distributions of ORFans lengths. We offer several possible biological explanations of this phenomenon

Search for excess showers from Crab Nebula

The arrival directions of muon poor showers registrated in the Tien Shan experiment during an effective running time about I,8.IO(4)h were analyzed. It is shown that there is a significant excess of these showers coming the direction of Crab Nebula

Solvothermal Synthesis of Sm3+-doped Fe3O4 nanoparticles

Magnetic iron oxide nanoparticles doped with samarium were prepared by solvothermal polyol method. An introduction of 2,2'-bipyridine during the synthesis reduces the particle diameter to about 9 nm in average. The difference in physical and magnetic properties of the samples prepared with and without capping agent was outlined on the basis of complex characterization by a number of experimental techniques. The characteristics of resulted product make it suitable for biomedical applications, for instance, as a contrast agent for MR

Experimental investigation of radiative-acoustic effects in the water by the thermodynamical conditions of Dumand

The value of the sound pulse produced by a high energy neutrino, if the thermoacoustical mechanism of sound generation takes place, is proportional to the density of energy absorbed, the coefficient of thermal expansion, the sound velocity, and the specific heat all of which depend on temperature, pressure and the salt content of the water

Formal security model for virtual machine hypervisors in cloud computing systems

The paper describes a formal security model for virtual machine hypervisors in cloud systems based on the graph theory. This model defines security properties and data access operations hierarchy inside virtual machines and hypervisors in the cloud. The proposed model makes it possible to formalize major security issues for cloud systems and define tasks for hypervisor security and methods to solve them as well as the security condition for the virtual machine hypervisors

Generation of 10^15 - 10^17 eV photons by UHE CR in the Galactic magnetic filed

We show that the deep expected in the diffuse photon spectrum above the threshold of e+e- pair production, i.e., at energies 10^15 - 10^17 eV, may be absent due to the synchrotron radiation by the electron component of the extragalactic Ultra-High Energy Cosmic Rays (UHE CR) in the Galactic magnetic filed. The mechanism we propose requires small (less than 2x10^-12 G) extragalactic magnetic fields and large fraction of photons in the UHE CR. For a typical photon flux expected in top-down scenarios of UHE CR, the predicted flux in the region of the deep is close to the existing experimental limit. The sensitivity of our mechanism to the extragalactic magnetic field may be used to improve existing bounds on the latter by two orders of magnitude.Comment: 11 pages, LaTeX, 1 .ps figure. Numerical error corrected; references adde

Alignment in Gamma-Hadron Families of Cosmic Rays

Alignment of main fluxes of energy in a target plane is found in families of cosmic ray particles detected in deep lead X-ray chambers. The fraction of events with alignment is unexpectedly large for families with high energy and large number of hadrons. This can be considered as evidence for the existence of coplanar scattering of secondary particles in interaction of particles with superhigh energy, $E_0 > 10^{16}$ eV. Data analysis suggests that production of most aligned groups occurs low above the chamber and is characterized by a coplanar scattering and quasiscaling spectrum of secondaries in the fragmentation region. The most elaborated hypothesis for explanation of alignment is related to the quark-gluon string rupture. However, the problem of theoretical interpretation of our results still remains open.Comment: 15 pages, 2 tables, 6 figures (not included), Stanford University preprint SU-ITP-94-2