2,356 research outputs found
The Big Pet Diabetes Survey: Perceived Frequency and Triggers for Euthanasia
Current pet diabetes mellitus (DM) treatment necessitates the active daily involvement of owners and can be costly. The current study aimed to investigate the owner population which opts for euthanasia instead of DM treatment. A survey was designed using multiple feedback steps and made available online to veterinarians world-wide. A total of 1192 veterinarians completed the survey and suggested a median one in 10 diabetic pets are euthanased at diagnosis; a further median one in 10 within one year because of lack of success or compliance. Perceived most important motivating factors included âpresence concurrent diseaseâ (45% respondents); âcostsâ (44%); âanimal ageâ (37%); âproblems obtaining adequate controlâ (35%); âpet welfareâ (35%); and âimpact ownerâs lifestyleâ (32%). Cats in Canadian (odds ratio (OR) 2.7), Australian (OR 2.3), rural (OR 1.6) and mixed (OR 1.7) practices were more likely to be euthanased because of DM diagnosis, while cats presented to referral/university were less likely to be euthanased (OR 0.6). Dogs were more likely to be euthanased because of DM in Canadian (OR 1.8), rural (OR 1.8) and mixed (OR 1.6) practices. The survey results suggest that benefit exists in improved DM education with emphasis on offering a choice of treatment styles ranging from intense and expensive to hands-off and cheap
Investigation of Collision Welding by High-Speed Imaging
Collision welding bases on the oblique collision of two joining partners at high relative
velocities. Until today, the mechanisms of collision welding are not yet fully understood
due to the variety of phenomena occurring during the collision. One of these phenomena is
the cloud of particles whose influence on bond formation has been neglected concerning
its stored thermal energy. For the investigation of this influence, a collision welding model
test rig was used which allowed the precise adjustment of the process parameters. The
process observation was implemented by an image intensifier camera to visualize the
ongoing collision and the occurring process phenomena. In this manuscript the developed
methodology and the results of high-speed process observation are presented. The findings
confirmed previous research regarding the shape formation of the cloud of particles and
the influence on bond formation. It was found that the temperature of the cloud of particles
depends strongly on the collision angle. Furthermore, an accumulation of the cloud of
particles during the collision process was recorded which might influence the steadiness of
the welding process
Serum N-Terminal Type III Procollagen Propeptide: An Indicator of Growth Hormone Excess and Response to Treatment in Feline Hypersomatotropism
BACKGROUND: Nâterminal type III procollagen propeptide (PIIINP) is a biomarker of soft tissue proliferation. Hypersomatotropism (HS) is associated with soft tissue proliferation. HYPOTHESIS: Serum PIIINP is increased in cats with HS and decreases with effective treatment, and may be an additional tool in the diagnosis and treatment of feline HS. ANIMALS: Cats with uncomplicated diabetes mellitus (DM; n = 30) and with HSâinduced DM (HSDM; n = 30). Preâ and posttreatment samples were available from 5 cats undergoing radiotherapy (RT) and 16 cats undergoing hypophysectomy (HPX). METHODS: Retrospective and prospective crossâsectional study. Analytical performance of a serum PIIINP ELISA was assessed and validated for use in cats. PIIINP and insulinâlike growth factor 1 (IGFâ1) radioimmunoassays (RIA) were performed preâ and postâtreatment in cats with DM and HSDM. PIIINP and IGFâ1 were compared between cats treated by RT and HPX. RESULTS: Serum PIIINP concentrations were significantly higher (P < .001) in HSDM cats (median, 19.6 ng/mL; range, 1.7â27.9) compared to DM cats (median, 5.0 ng/mL; range, 2.1â10.4). A cutâoff of 10.5 ng/mL allowed differentiation between DM and HSDM cats with 87% sensitivity and 100% specificity (area under the curve [AUC], 0.91; 95% confidence interval [CI], 0.82â1). After RT, PIIINP increased significantly (P = .043) with no significant change in IGFâ1 concentrations. After HPX, serum PIIINP (P = .034) and IGFâ1 concentrations (P < .001) decreased significantly. CONCLUSION AND CLINICAL IMPORTANCE: PIIINP concentrations are increased in cats with untreated HSDM compared to those with DM, demonstrating the effect of excess GH on soft tissue. PIIINP concentrations decreased after HPX in most HSDM cats
Epidemiology of diabetes mellitus among 193,435 cats attending primary-care veterinary practices in England
BACKGROUND: Diabetes mellitus (DM) is a common endocrine disease of cats. The prevalence of DM in cats in England is not wellâdefined. HYPOTHESIS/OBJECTIVES: To estimate the prevalence and identify risk factors for DM in a large population of cats attending primaryâcare practices. ANIMALS: A cohort of 193,563 cats in the VetCompass Programme attending 118 primaryâcare practices in England. METHODS: Crossâsectional analysis of cohort clinical data. Data were extracted covering September 1st 2009 and August 31st 2014. Period prevalence of DM was calculated. Associations between risk factors and DM were assessed using logistic regression modelling. RESULTS: Of 1,128 DM cases were identified among 194,563 cats (period prevalence 0.58%; 95% confidence interval [CI] 0.54â0.61). Multivariable modelling indicated that Tonkinese (OR 4.1; 95% CI 1.8â9.6; P = .001), Norwegian Forest (odds ratio [OR] 3.5; 95% CI 1.3â9.6; P = .001) and Burmese (OR 3.0; 95% CI 2.0â4.4; P < .001) cats had increased odds of DM compared with crossbred cats. DM odds increased as bodyweight categories increased above 4 kg (P < .001), as cats aged beyond 6 years old (P < .001) and in insured cats (OR 2.0; 95% CI 1.6â2.4; P < .001) but sex was not significantly associated with DM. CONCLUSIONS AND CLINICAL IMPORTANCE: Diabetes mellitus is an important component of the primaryâcare practice caseload with 1âinâ200 cats affected. An increased risk of DM in certain cat breeds supports a genetic predisposition. These results can guide future research and preventative healthcare
The Meaning of Jewish-Catholic Encounter in the Austrian Refugee Camps
This study takes its point of departure from reports of antisemitic incidents among Hungarians in Austrian refugee camps at the end of 1956. These incidents may have been provoked by agents from Communist Hungary who had penetrated the camps and found ground for provocation among the refugees. The author argues their true significance should be sought in the contemporary history of Catholic Hungary and Austria. Special attention is given to the biography of the journalist and historian, Friedrich Heer, and the priest, Leopold Ungar, who challenged the Austrian church to greater openness. An additional analysis is provided of the confrontation with the Catholic Jewish question conducted by Fathers György Kis, John Ăsterreicher, and Alois Eckert. The engagement of Eckert and Ungar with the Hungarian refugees emerges as a prelude to the reconciliation of the Catholic Church with Judaism in the constitution Nostra Aetate of the Second Vatican Council
Reply to Comment on "Exact analytic solution for the generalized Lyapunov exponent of the 2-dimensional Anderson localization"
We reply to comments by P.Marko, L.Schweitzer and M.Weyrauch
[preceding paper] on our recent paper [J. Phys.: Condens. Matter 63, 13777
(2002)]. We demonstrate that our quite different viewpoints stem for the
different physical assumptions made prior to the choice of the mathematical
formalism. The authors of the Comment expect \emph{a priori} to see a single
thermodynamic phase while our approach is capable of detecting co-existence of
distinct pure phases. The limitations of the transfer matrix techniques for the
multi-dimensional Anderson localization problem are discussed.Comment: 4 pages, accepted for publication in J.Phys.: Condens. Mat
Heritage and Repatriation in the History of Habsburg and Hungarian Archives
Hungaryâs National Library and National Archives seek to collect, as exhaustively as possible, information sources defined as Hungarica: created by, or about, Hungary or Hungarians. Modern archival practice privileges the principle of provenance (the identity of the author or records creator) in determining what an archive should acquire. The Hungarian governmentâs Mikes Kelemen Program, founded in 2013, builds on earlier efforts for the acquisition of foreign Hungarica publications and manuscripts, defined by the Hungarian identity of the author. But because Hungarians living in the diaspora are not only Hungarian, sensitivity to the heritage and collecting interests of the diaspora host country is recommended
Pilot assessment of two computer-generated display formats for helicopter instrument approach
Two computer generated display formats were evaluated as primary displays by six research pilots in a fixed base simulator. One of the computer generated display formats was an electronic attitude director indicator (EADI) which featured three cue flight director, command information, superimposed on true perspective runway symbology. The other computer generated display format featured separate horizontal and vertical situation information with vector predictors. A baseline display, consisting of an electromechanical attitude director indicator (ADI) with a three cue flight director and a moving map, was used as a reference for the pilot evaluations
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