Reduced Context Effects on Retrieval in First-Episode Schizophrenia

Background: A recent modeling study by the authors predicted that contextual information is poorly integrated into episodic representations in schizophrenia, and that this is a main cause of the retrieval deficits seen in schizophrenia. Methodology/Principal Findings: We have tested this prediction in patients with first-episode schizophrenia and matched controls. The benefit from contextual cues in retrieval was strongly reduced in patients. On the other hand, retrieval based on item cues was spared. Conclusions/Significance: These results suggest that reduced integration of context information into episodic representations is a core deficit in schizophrenia and one of the main causes of episodic memory impairment

Microwave radiometric observations near 19.35, 92 and 183 GHz of precipitation in tropical storm Cora

Observations of rain cells in the remains of a decaying tropical storm were made by Airborne Microwave Radiometers at 19.35,92 and three frequencies near 183 GHz. Extremely low brightness temperatures, as low as 140 K were noted in the 92 and 183 GHz observations. These can be accounted for by the ice often associated with raindrop formation. Further, 183 GHz observations can be interpreted in terms of the height of the ice. The brightness temperatures observed suggest the presence of precipitation sized ice as high as 9 km or more

Rain observations in tropical storm Cora

Passive microwave observations were made in tropical storm Cora at 19.35 and 94GHz. These observations suggest that 94GHz is appropriate for mapping the extent of rain over either land or ocean backgrounds and that some rainfall intensity measurement is also possible

Vanadium (β-(Dimethylamino)ethyl)cyclopentadienyl Complexes with Diphenylacetylene Ligands

Reduction of the V(III) (β-(dimethylamino)ethyl)cyclopentadienyl dichloride complex [η5:η1-C5H4(CH2)2NMe2]VCl2(PMe3) with 1 equiv of Na/Hg yielded the V(II) dimer {[η5:η1-C5H4(CH2)2NMe2]V(µ-Cl)}2 (2). This compound reacted with diphenylacetylene in THF to give the V(II) alkyne adduct [η5:η1-C5H4(CH2)2NMe2]VCl(η2-PhC≡CPh). Further reduction of 2 with Mg in the presence of diphenylacetylene resulted in oxidative coupling of two diphenylacetylene groups to yield the diamagnetic, formally V(V), bent metallacyclopentatriene complex [η5:η1-C5H4(CH2)2NMe2]V(C4Ph4).

Study protocol to investigate the effect of a lifestyle intervention on body weight, psychological health status and risk factors associated with disease recurrence in women recovering from breast cancer treatment

Background Breast cancer survivors often encounter physiological and psychological problems related to their diagnosis and treatment that can influence long-term prognosis. The aim of this research is to investigate the effects of a lifestyle intervention on body weight and psychological well-being in women recovering from breast cancer treatment, and to determine the relationship between changes in these variables and biomarkers associated with disease recurrence and survival. Methods/design Following ethical approval, a total of 100 patients will be randomly assigned to a lifestyle intervention (incorporating dietary energy restriction in conjunction with aerobic exercise training) or normal care control group. Patients randomised to the dietary and exercise intervention will be given individualised healthy eating dietary advice and written information and attend moderate intensity aerobic exercise sessions on three to five days per week for a period of 24 weeks. The aim of this strategy is to induce a steady weight loss of up to 0.5 Kg each week. In addition, the overall quality of the diet will be examined with a view to (i) reducing the dietary intake of fat to ~25% of the total calories, (ii) eating at least 5 portions of fruit and vegetables a day, (iii) increasing the intake of fibre and reducing refined carbohydrates, and (iv) taking moderate amounts of alcohol. Outcome measures will include body weight and body composition, psychological health status (stress and depression), cardiorespiratory fitness and quality of life. In addition, biomarkers associated with disease recurrence, including stress hormones, estrogen status, inflammatory markers and indices of innate and adaptive immune function will be monitored. Discussion This research will provide valuable information on the effectiveness of a practical, easily implemented lifestyle intervention for evoking positive effects on body weight and psychological well-being, two important factors that can influence long-term prognosis in breast cancer survivors. However, the added value of the study is that it will also evaluate the effects of the lifestyle intervention on a range of biomarkers associated with disease recurrence and survival. Considered together, the results should improve our understanding of the potential role that lifestyle-modifiable factors could play in saving or prolonging lives

Preliminary Results: Complementary C4:C3 Grazing Systems

Native warm-season grasses (NWSG) can produce high quality forage and high rates of gain for beef cattle. However, little data is available on how NWSG affect the productivity of cow-calf operations on a farm scale. Therefore, we implemented an experiment at three sites, Booneville, AR, Linneus, MO and Louisville, TN, with cow-calf pairs (mature cows over ≥ 3 years old, spring calving). We evaluated two forage systems that mix either a drought or drought/flood tolerant native C4 species [big bluestem (BB) blend or eastern gamagrass (EG)] with a cool-season perennial, tall fescue (TF), and compared them to the most frequently used forage system within the Fescue Belt region, one that relies on TF only. The TN study site contains EG, with big bluestem at the MO site, and both big bluestem and EG at the AR site. Cattle (n = 12 pairs per experimental unit) were weighed yearly before initial grazing and again after final removal. Forage samples (n = 15) were collected at the beginning of grazing and once every twenty-eight days during the grazing season, and finally, at the conclusion of grazing. Harvested forages were tested for forage nutritive content (CP, NDF, ADF) using NIRS. Hay produced per forage system was documented by counting bales and weights of subsamples. The AR site was not able to participate in the first year of the study. Overall, there were no statistical differences between treatments in the first grazing season for either cattle or forage measures. However, cattle spent less time on NWSG in 2021 at the TN site to enable renovation of EG to be completed. Also, TF stands had a significant proportion of volunteer warm-season grasses within the pastures. Data from the second year of the study are currently under analysis

Atomic-scale modeling of the deformation of nanocrystalline metals

Nanocrystalline metals, i.e. metals with grain sizes from 5 to 50 nm, display technologically interesting properties, such as dramatically increased hardness, increasing with decreasing grain size. Due to the small grain size, direct atomic-scale simulations of plastic deformation of these materials are possible, as such a polycrystalline system can be modeled with the computational resources available today. We present molecular dynamics simulations of nanocrystalline copper with grain sizes up to 13 nm. Two different deformation mechanisms are active, one is deformation through the motion of dislocations, the other is sliding in the grain boundaries. At the grain sizes studied here the latter dominates, leading to a softening as the grain size is reduced. This implies that there is an ``optimal'' grain size, where the hardness is maximal. Since the grain boundaries participate actively in the deformation, it is interesting to study the effects of introducing impurity atoms in the grain boundaries. We study how silver atoms in the grain boundaries influence the mechanical properties of nanocrystalline copper.Comment: 10 pages, LaTeX2e, PS figures and sty files included. To appear in Mater. Res. Soc. Symp. Proc. vol 538 (invited paper). For related papers, see http://www.fysik.dtu.dk/~schiotz/publist.htm