1,780 research outputs found
Teaching for learning with technology: a faculty development initiative at a research university
This paper reviews recent literature addressing the state of
technology in higher education as a backdrop for a faculty
development program offered annually at Northwestern. First,
we will present the state of technology related to teaching in
three areas: (1) the varied institutional interest in technology,
(2) the variance in faculty engagement with technology, and (3)
factors that influence faculty acceptance of technology. Next,
we will introduce Northwestern’s response to the need for
faculty development related to technology, the 5-day Teaching
and Learning with Technology workshop. Finally, we will
present data gathered over two years that demonstrates how
pedagogically-driven technology training can enhance teaching
and encourage faculty to embrace technology in teaching to
accomplish pedagogically-based learning objectives
Quantum teleportation between light and matter
Quantum teleportation is an important ingredient in distributed quantum
networks, and can also serve as an elementary operation in quantum computers.
Teleportation was first demonstrated as a transfer of a quantum state of light
onto another light beam; later developments used optical relays and
demonstrated entanglement swapping for continuous variables. The teleportation
of a quantum state between two single material particles (trapped ions) has now
also been achieved. Here we demonstrate teleportation between objects of a
different nature - light and matter, which respectively represent 'flying' and
'stationary' media. A quantum state encoded in a light pulse is teleported onto
a macroscopic object (an atomic ensemble containing 10^12 caesium atoms).
Deterministic teleportation is achieved for sets of coherent states with mean
photon number (n) up to a few hundred. The fidelities are 0.58+-0.02 for n=20
and 0.60+-0.02 for n=5 - higher than any classical state transfer can possibly
achieve. Besides being of fundamental interest, teleportation using a
macroscopic atomic ensemble is relevant for the practical implementation of a
quantum repeater. An important factor for the implementation of quantum
networks is the teleportation distance between transmitter and receiver; this
is 0.5 metres in the present experiment. As our experiment uses propagating
light to achieve the entanglement of light and atoms required for
teleportation, the present approach should be scalable to longer distances.Comment: 23 pages, 8 figures, incl. supplementary informatio
The Affective Impact of Financial Skewness on Neural Activity and Choice
Few finance theories consider the influence of “skewness” (or large and asymmetric but unlikely outcomes) on financial choice. We investigated the impact of skewed gambles on subjects' neural activity, self-reported affective responses, and subsequent preferences using functional magnetic resonance imaging (FMRI). Neurally, skewed gambles elicited more anterior insula activation than symmetric gambles equated for expected value and variance, and positively skewed gambles also specifically elicited more nucleus accumbens (NAcc) activation than negatively skewed gambles. Affectively, positively skewed gambles elicited more positive arousal and negatively skewed gambles elicited more negative arousal than symmetric gambles equated for expected value and variance. Subjects also preferred positively skewed gambles more, but negatively skewed gambles less than symmetric gambles of equal expected value. Individual differences in both NAcc activity and positive arousal predicted preferences for positively skewed gambles. These findings support an anticipatory affect account in which statistical properties of gambles—including skewness—can influence neural activity, affective responses, and ultimately, choice
Trends in Radical Prostatectomy: Centralization, Robotics, and Access to Urologic Cancer Care
Robotic surgery has been widely adopted for radical prostatectomy. We hypothesize that this change is rapidly shifting procedures away from hospitals that do not offer robotics and consequently increasing patient travel
Mapping coherence in measurement via full quantum tomography of a hybrid optical detector
Quantum states and measurements exhibit wave-like --- continuous, or
particle-like --- discrete, character. Hybrid discrete-continuous photonic
systems are key to investigating fundamental quantum phenomena, generating
superpositions of macroscopic states, and form essential resources for
quantum-enhanced applications, e.g. entanglement distillation and quantum
computation, as well as highly efficient optical telecommunications. Realizing
the full potential of these hybrid systems requires quantum-optical
measurements sensitive to complementary observables such as field quadrature
amplitude and photon number. However, a thorough understanding of the practical
performance of an optical detector interpolating between these two regions is
absent. Here, we report the implementation of full quantum detector tomography,
enabling the characterization of the simultaneous wave and photon-number
sensitivities of quantum-optical detectors. This yields the largest
parametrization to-date in quantum tomography experiments, requiring the
development of novel theoretical tools. Our results reveal the role of
coherence in quantum measurements and demonstrate the tunability of hybrid
quantum-optical detectors.Comment: 7 pages, 3 figure
Prevalence and context of firearms-related problems in child protective service investigations
Background: Despite the significance of firearm safety, we need additional data to understand the prevalence and context surrounding firearm-related problems within the child welfare system.
Objective: Estimate proportion of cases reporting a firearm-related problem during case initiation and the contexts in which these problems exist.
Sample and setting: 75,809 caseworker-written investigation summaries that represented all substantiated referrals of maltreatment in Michigan from 2015 to 2017.
Methods: We developed an expert dictionary of firearm-related terms to search investigation summaries. We retrieved summaries that contained any of the terms to confirm whether a firearm was present (construct accurate) and whether it posed a threat to the child. Finally, we coded summaries that contained firearm-related problems to identify contexts in which problems exist.
Results: Of the 75,809 substantiated cases, the dictionary flagged 2397 cases that used a firearm term (3.2 %), with a construct accuracy rate of 96 %. Among construct accurate cases, 79 % contained a firearm-related problem. The most common intent for a firearm-related problem was violence against a person (45 %). The co-occurrence of domestic violence and/or substance use with a firearm-related problem was high (41 % and 48 %, respectively). 49 % of summaries that contained a firearm-related problem did not provide information regarding storage.
Conclusion: When caseworkers document a firearm within investigative summaries, a firearm-related risk to the child likely exists. Improved documentation of firearms and storage practices among investigated families may better identify families needing firearm-related services
Capsule carbohydrate structure determines virulence in Acinetobacter baumannii
Acinetobacter baumannii is a highly antibiotic-resistant bacterial pathogen for which novel therapeutic approaches are needed. Unfortunately, the drivers of virulence in A. baumannii remain uncertain. By comparing genomes among a panel of A. baumannii strains we identified a specific gene variation in the capsule locus that correlated with altered virulence. While less virulent strains possessed the intact gene gtr6, a hypervirulent clinical isolate contained a spontaneous transposon insertion in the same gene, resulting in the loss of a branchpoint in capsular carbohydrate structure. By constructing isogenic gtr6 mutants, we confirmed that gtr6-disrupted strains were protected from phagocytosis in vitro and displayed higher bacterial burden and lethality in vivo. Gtr6+ strains were phagocytized more readily and caused lower bacterial burden and no clinical illness in vivo. We found that the CR3 receptor mediated phagocytosis of gtr6+, but not gtr6-, strains in a complement-dependent manner. Furthermore, hypovirulent gtr6+ strains demonstrated increased virulence in vivo when CR3 function was abrogated. In summary, loss-of-function in a single capsule assembly gene dramatically altered virulence by inhibiting complement deposition and recognition by phagocytes across multiple A. baumannii strains. Thus, capsular structure can determine virulence among A. baumannii strains by altering bacterial interactions with host complement-mediated opsonophagocytosis
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