Graphic corresponding to the contingency table (Tab.II).

<p>Fischer exact test resulted in highly significance (p<0.0001). The sign of the ΔCVF is associated to specific Group: negative value is related to pathologic condition.</p

Mann-Whitney test demonstrates a significant difference (p<0.0001) in the comparison of the ΔCVF values between the group of healthy subjects (CTR) and the aggregated groups (1,2,3,4) of patients (MS).

<p>Mann-Whitney test demonstrates a significant difference (p<0.0001) in the comparison of the ΔCVF values between the group of healthy subjects (CTR) and the aggregated groups (1,2,3,4) of patients (MS).</p

Fisher's exact test applied to ΔCSA of right and left IJV within the two study groups: patients with MS (MS) and healthy subjects (CTR).

<p>The differences were not significant.</p

MS clinical summary data.

<p>MS clinical summary data.</p

Contingency table.

<p>CTR = healthy subjects; MS = patients with MS; ΔCVF = CVF in clinostatism - CVF in the seated position.</p

Box-and-Whiskers plot of ΔCVF within prevalent subgroups of MS and controls.

<p>Group 2: RRMS; Group 3: SPMS; Group 5: controls. There is a significant difference between Group 5 and the Groups 2 and 3.</p