A mutant of Neurospora crassa deficient in cytochrome c heme lyase activity cannot import cytochrome c into mitochondria

The nuclear cyt-2-1 mutant of Neurospora crassa is characterized by a gross deficiency of cytochrome c (Bertrand, H., and Collins, R. A. (1978) Mol. Gen. Genet. 166, 1-13). The mutant produces mRNA that can be translated into apocytochrome c in vitro. Apocytochrome c is also synthesized in vivo in cyt-2-1, but it is rapidly degraded and thus does not accumulate in the cytosol. Mitochondria from wild-type cells bind apocytochrome c made in vitro from either wild-type or cyt-2-1 mRNA and convert it to holocytochrome c. This conversion depends on the addition of heme by cytochrome c heme lyase and is coupled to translocation of cytochrome c into the intermembrane space. Mitochondria from the cyt-2-1 strain are deficient in the ability to bind apocytochrome c. They are also completely devoid of cytochrome c heme lyase activity. These defects explain the inability of the cyt-2-1 mutant to convert apocytochrome c to the holo form and to import it into mitochondria

Radiation effects on silver and zinc battery electrodes, III Interim report, Oct. 1965 - Jan. 1966

Radiation effects on silver-zinc battery electrode

Atlantic menhaden, Brevoortia tyrannus, Purse Seine Fishery, 1972-84, with a brief discussion of age and size composition of the Landings

This report summarizes (I) annual purse seine landings of Atlantic menhaden, Brevoortia tyrannus, for 1972-84, (2) estimated numbers of fish caught by fishing area. (3) estimates of nominal fishing effort and catch-per-unit-effort, (4) mean fish length and weight, and (5) major changes in the fishery. During the 1970s stock size and recruitment increased and the age composition broadened. reversing trends witnessed during the fishery's decline in the 1960s. Landings steadily improved and by 1980 the total coast wide landings exceeded 400,000 metric tons. Nevertheless, the character of the fishery changed considerably. Eleven reduction plants processed fish at seven ports in 1972, but in 1984 only eight plants operated at live ports. Beginning in the mid-1960s the center of fishing aclivity shifted from the Middle Atlantic area to the Chesapeake Bay area, which has continued to dominate the fishery in landings and effort through the 1970s and 1980s. During this period the average size and age of fish in the catches declined. (PDF file contains 30 pages.

Chaotic saddles in nonlinear modulational interactions in a plasma

A nonlinear model of modulational processes in the subsonic regime involving a linearly unstable wave and two linearly damped waves with different damping rates in a plasma is studied numerically. We compute the maximum Lyapunov exponent as a function of the damping rates in a two-parameter space, and identify shrimp-shaped self-similar structures in the parameter space. By varying the damping rate of the low-frequency wave, we construct bifurcation diagrams and focus on a saddle-node bifurcation and an interior crisis associated with a periodic window. We detect chaotic saddles and their stable and unstable manifolds, and demonstrate how the connection between two chaotic saddles via coupling unstable periodic orbits can result in a crisis-induced intermittency. The relevance of this work for the understanding of modulational processes observed in plasmas and fluids is discussed.Comment: Physics of Plasmas, in pres

Systematic study of Optical Feshbach Resonances in an ideal gas

Using a narrow intercombination line in alkaline earth atoms to mitigate large inelastic losses, we explore the Optical Feshbach Resonance (OFR) effect in an ultracold gas of bosonic $^{88}$Sr. A systematic measurement of three resonances allows precise determinations of the OFR strength and scaling law, in agreement with coupled-channels theory. Resonant enhancement of the complex scattering length leads to thermalization mediated by elastic and inelastic collisions in an otherwise ideal gas. OFR could be used to control atomic interactions with high spatial and temporal resolution.Comment: Significant changes to text and figure presentation to improve clarity. Extended supplementary material. 4 pages, 4 figures; includes supplementary material 8 pages, 4 figures. Submitted to Physical Review Letter

A General Framework for Computing Optimal Correlated Equilibria in Compact Games

We analyze the problem of computing a correlated equilibrium that optimizes some objective (e.g., social welfare). Papadimitriou and Roughgarden [2008] gave a sufficient condition for the tractability of this problem; however, this condition only applies to a subset of existing representations. We propose a different algorithmic approach for the optimal CE problem that applies to all compact representations, and give a sufficient condition that generalizes that of Papadimitriou and Roughgarden. In particular, we reduce the optimal CE problem to the deviation-adjusted social welfare problem, a combinatorial optimization problem closely related to the optimal social welfare problem. This framework allows us to identify new classes of games for which the optimal CE problem is tractable; we show that graphical polymatrix games on tree graphs are one example. We also study the problem of computing the optimal coarse correlated equilibrium, a solution concept closely related to CE. Using a similar approach we derive a sufficient condition for this problem, and use it to prove that the problem is tractable for singleton congestion games.Comment: 14 pages. Short version to appear in WINE 201

Manufacturing in space: Fluid dynamics numerical analysis

Numerical computations were performed for natural convection in circular enclosures under various conditions of acceleration. It was found that subcritical acceleration vectors applied in the direction of the temperature gradient will lead to an eventual state of rest regardless of the initial state of motion. Supercritical acceleration vectors will lead to the same steady state condition of motion regardless of the initial state of motion. Convection velocities were computed for acceleration vectors at various angles of the initial temperature gradient. The results for Rayleigh numbers of 1000 or less were found to closely follow Weinbaum's first order theory. Higher Rayleigh number results were shown to depart significantly from the first order theory. Supercritical behavior was confirmed for Rayleigh numbers greater than the known supercritical value of 9216. Response times were determined to provide an indication of the time required to change states of motion for the various cases considered