40 research outputs found
Global age-sex-specific fertility, mortality, healthy life expectancy (HALE), and population estimates in 204 countries and territories, 1950-2019 : a comprehensive demographic analysis for the Global Burden of Disease Study 2019
- Author
- Abbas KM
- Abbasi-Kangevari M
- Abbasifard M
- Abbastabar H
- Abd El Razek HM
- Abd El Razek MM
- Abd-Allah F
- Abdelalim A
- Abdulkader RS
- Abdullah KH
- Abolhassani H
- Abreu LG
- Abrigo MRM
- Abushouk AI
- Adabi M
- Adair T
- Adebayo OM
- Adedeji IA
- Adekanmbi V
- Adeoye AM
- Adetokunboh OO
- Advani SM
- Afshin A
- Aghaali M
- Agrawal A
- Ahmadi K
- Ahmadieh H
- Ahmed MB
- Al-Aly Z
- Al-Mekhlafi HM
- Alam K
- Alam T
- Alanezi FM
- Alanzi TM
- Alcalde-Rabanal JE
- Ali M
- Alicandro G
- Alijanzadeh M
- Alinia C
- Alipour V
- Alizade H
- Aljunid SM
- Allebeck P
- Almadi MAH
- Almasi-Hashiani A
- Altirkawi KA
- Alumran AK
- Alvis-Guzman N
- Amini-Rarani M
- Aminorroaya A
- Amit AML
- Ancuceanu R
- Andrei CL
- Androudi S
- Angus C
- Anjomshoa M
- Ansari F
- Ansari I
- Ansari-Moghaddam A
- Antonio CAT
- Antony CM
- Anvari D
- Appiah SCY
- Arab-Zozani M
- Arabloo J
- Aravkin AY
- Aremu O
- Arnlov J
- Aryal KK
- Asadi-Pooya AA
- Asgari S
- Atteraya MS
- Ausloos M
- Avila-Burgos L
- Avokpaho EFGA
- Ayano G
- Ayanore MA
- Azarian G
- Babaee E
- Badiye AD
- Bagli E
- Bahrami MA
- Bakhtiari A
- Balassyano S
- Bali AO
- Banach M
- Bandpei MAM
- Banik PC
- Barker-Collo SL
- Barnighausen TW
- Barzegar A
- Basu S
- Baune BT
- Bayati M
- Bazmandegan G
- Bedi N
- Bell ML
- Bennett DA
- Bensenor IM
- Berhe K
- Berman AE
- Bertolacci GJ
- Bhageerathy R
- Bhala N
- Bhattacharyya K
- Bhutta ZA
- Bijani A
- Bin Zaman S
- Biondi A
- Bisanzio D
- Bisignano C
- Biswas RK
- Bjrge T
- Bohlouli S
- Bohluli M
- Bolla SRR
- Borzi AM
- Borzouei S
- Brady OJ
- Braithwaite D
- Brauer M
- Briko AN
- Briko NI
- Bumgarner BR
- Butt ZA
- Cai T
- Callender CSKH
- Camera LLAA
- Campos-Nonato IR
- Car LT
- Cardenas R
- Carreras G
- Carrero JJ
- Carvalho F
- Castaldelli-Maia JM
- Castelpietra G
- Castro F
- Catala-Lopez F
- Cederroth CR
- Cerin E
- Chattu VK
- Chin KL
- Chu D-T
- Ciobanu LG
- Cirillo M
- Comfort H
- Costa VM
- Cowden RG
- Cromwell EA
- Croneberger AJ
- Cunningham M
- D'Amico E
- da Silva DD
- Dahlawi SMA
- Damiani G
- Dandona L
- Dandona R
- Dargan PI
- Darwesh AM
- Daryani A
- Das Gupta R
- das Neves J
- Davletov K
- De Leo D
- Defo BK
- Denova-Gutierrez E
- Deribe K
- Dervenis N
- Desai R
- Dhungana GP
- Diaz D
- Dippenaar IN
- Djalalinia S
- Do HT
- Dokova K
- Doku DT
- Dorostkar F
- dos Santos FLC
- Doshi CP
- Doshmangir L
- Doyle KE
- Dubljanin E
- Duraes AR
- Edvardsson D
- Effiong A
- El Sayed I
- El Tantawi M
- El-Jaafary SI
- Elbarazi I
- Emamian MH
- Eskandarieh S
- Esmaeilzadeh F
- Estep K
- Farahmand M
- Faraj A
- Fareed M
- Faridnia R
- Faro A
- Farzadfar F
- Fattahi N
- Fazaeli AA
- Fazlzadeh M
- Feigin VL
- Fereshtehnejad S-M
- Fernandes E
- Ferreira ML
- Filip I
- Fischer F
- Flohr C
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- Folayan MO
- Fomenkov AA
- Freitas M
- Fukumoto T
- Fuller JE
- Furtado JM
- Gad MM
- Gakidou E
- Gallus S
- Gebrehiwot AM
- Gebremedhin KB
- Gething PW
- Ghamari F
- Ghashghaee A
- Gholamian A
- Gilani SA
- Gitimoghaddam M
- Glushkova EV
- Gnedovskaya EV
- Gopalani SV
- Goulart AC
- Gugnani HC
- Guo Y
- Gupta R
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- Haagsma JA
- Haj-Mirzaian A
- Haj-Mirzaian A
- Halvaei I
- Hamadeh RR
- Han C
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- Hankey GJ
- Haririan H
- Haro JM
- Hasaballah AI
- Hassanipour S
- Hassankhani H
- Hay SI
- Heibati B
- Heidari-Soureshjani R
- Henny K
- Henry NJ
- Herteliu C
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- Hole MK
- Hoogar P
- Hosgood HD
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- Hosseinzadeh M
- Hostiuc M
- Hostiuc S
- Househ M
- Hoy DG
- Hu G
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- Ibitoye SE
- Ikuta KS
- Il Shin J
- Ilesanmi OS
- Ilic IM
- Ilic MD
- Imani-Nasab MH
- Islam M
- Iso H
- Iwu CJ
- Jaafari J
- Jacobsen KH
- Jafarabadi MA
- Jahagirdar D
- Jahanmehr N
- Jalali A
- Jalilian F
- James SL
- Janjani H
- Jenabi E
- Jha RP
- Jha V
- Ji JS
- Jonas JB
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- Jurisson M
- Kabir Z
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- Kayode GA
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- Khater MM
- Khazaei S
- Khazaie H
- Khodayari MT
- Khubchandani J
- Kianipour N
- Kim C-I
- Kim Y-E
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- Kisa A
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- Kivimaki M
- Komaki H
- Kopec JA
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- Koul PA
- Koyanagi A
- Kravchenko MA
- Krishan K
- Krohn KJ
- Kumar GA
- Kumar M
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- Kusuma D
- Kyu HH
- La Vecchia C
- Lacey B
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- Lee SWH
- Leever AT
- LeGrand KE
- Leonardi M
- Li S
- Lim L-L
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- Lodha R
- Logroscino G
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- Lopukhov PD
- Lotufo PA
- Lozano R
- Lu A
- Lunevicius R
- Madadin M
- Maddison ER
- Mahasha PW
- Mahdavi MM
- Mahesh PA
- Malekzadeh R
- Mamun AA
- Manafi N
- Mansour-Ghanaei F
- Mansouri B
- Mansournia MA
- Mapoma CC
- Martini S
- Martins-Melo FR
- Masaka A
- Mastrogiacomo CI
- Mathur MR
- May EA
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- McKee M
- Mehndiratta MM
- Mehri F
- Mehta KM
- Meitei WB
- Memiah PTN
- Mendoza W
- Menezes RG
- Mengesha EW
- Mensah GA
- Meretoja A
- Meretoja TJ
- Mestrovic T
- Mezerji NMG
- Michalek IM
- Mihretie KM
- Miller TR
- Mills EJ
- Milne GJ
- Mirrakhimov EM
- Mirzaei H
- Mirzaei M
- Mirzaei-Alavijeh M
- Misganaw AT
- Moazen B
- Moghadam TZ
- Moghadaszadeh M
- Moghaddam SS
- Mohamadi E
- Mohammad DK
- Mohammad Y
- Mohammadbeigi A
- Mohammadian-Hafshejani A
- Mohammadpourhodki R
- Mohammed H
- Mohammed S
- Mohebi F
- Mokari A
- Mokdad AH
- Momen NC
- Monasta L
- Mooney MD
- Moradi G
- Moradi M
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- Moradzadeh R
- Moraga P
- Morgado-da-Costa J
- Morrison SD
- Mosser JF
- Motlagh SN
- Mouodi S
- Mousavi SM
- Mueller UO
- Murray CJL
- Musa KI
- Muthupandian S
- Nabavizadeh B
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- Naghavi M
- Naghshtabrizi B
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- Negoi I
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- Nguyen HLT
- Nguyen TH
- Nigatu YT
- Nikbakhsh R
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- Pepito VCF
- Peprah EK
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- Pourmalek F
- Pourshams A
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- Prada SI
- Prakash S
- Preotescu L
- Quintanilla BPA
- Rabiee M
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- Shahabi S
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- Shams-Beyranvand M
- Shamsi M
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- Shannawaz M
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- Zamanian M
- Zandian H
- Zhang Z-J
- Zheng P
- Zhou M
- Ziapour A
- Publication venue
- Publication date
- 01/01/2020
- Field of study
Background Accurate and up-to-date assessment of demographic metrics is crucial for understanding a wide range of social, economic, and public health issues that affect populations worldwide. The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2019 produced updated and comprehensive demographic assessments of the key indicators of fertility, mortality, migration, and population for 204 countries and territories and selected subnational locations from 1950 to 2019. Methods 8078 country-years of vital registration and sample registration data, 938 surveys, 349 censuses, and 238 other sources were identified and used to estimate age-specific fertility. Spatiotemporal Gaussian process regression (ST-GPR) was used to generate age-specific fertility rates for 5-year age groups between ages 15 and 49 years. With extensions to age groups 10-14 and 50-54 years, the total fertility rate (TFR) was then aggregated using the estimated age-specific fertility between ages 10 and 54 years. 7417 sources were used for under-5 mortality estimation and 7355 for adult mortality. ST-GPR was used to synthesise data sources after correction for known biases. Adult mortality was measured as the probability of death between ages 15 and 60 years based on vital registration, sample registration, and sibling histories, and was also estimated using ST-GPR. HIV-free life tables were then estimated using estimates of under-5 and adult mortality rates using a relational model life table system created for GBD, which closely tracks observed age-specific mortality rates from complete vital registration when available. Independent estimates of HIV-specific mortality generated by an epidemiological analysis of HIV prevalence surveys and antenatal clinic serosurveillance and other sources were incorporated into the estimates in countries with large epidemics. Annual and single-year age estimates of net migration and population for each country and territory were generated using a Bayesian hierarchical cohort component model that analysed estimated age-specific fertility and mortality rates along with 1250 censuses and 747 population registry years. We classified location-years into seven categories on the basis of the natural rate of increase in population (calculated by subtracting the crude death rate from the crude birth rate) and the net migration rate. We computed healthy life expectancy (HALE) using years lived with disability (YLDs) per capita, life tables, and standard demographic methods. Uncertainty was propagated throughout the demographic estimation process, including fertility, mortality, and population, with 1000 draw-level estimates produced for each metric. Findings The global TFR decreased from 2.72 (95% uncertainty interval [UI] 2.66-2.79) in 2000 to 2.31 (2.17-2.46) in 2019. Global annual livebirths increased from 134.5 million (131.5-137.8) in 2000 to a peak of 139.6 million (133.0-146.9) in 2016. Global livebirths then declined to 135.3 million (127.2-144.1) in 2019. Of the 204 countries and territories included in this study, in 2019, 102 had a TFR lower than 2.1, which is considered a good approximation of replacement-level fertility. All countries in sub-Saharan Africa had TFRs above replacement level in 2019 and accounted for 27.1% (95% UI 26.4-27.8) of global livebirths. Global life expectancy at birth increased from 67.2 years (95% UI 66.8-67.6) in 2000 to 73.5 years (72.8-74.3) in 2019. The total number of deaths increased from 50.7 million (49.5-51.9) in 2000 to 56.5 million (53.7-59.2) in 2019. Under-5 deaths declined from 9.6 million (9.1-10.3) in 2000 to 5.0 million (4.3-6.0) in 2019. Global population increased by 25.7%, from 6.2 billion (6.0-6.3) in 2000 to 7.7 billion (7.5-8.0) in 2019. In 2019, 34 countries had negative natural rates of increase; in 17 of these, the population declined because immigration was not sufficient to counteract the negative rate of decline. Globally, HALE increased from 58.6 years (56.1-60.8) in 2000 to 63.5 years (60.8-66.1) in 2019. HALE increased in 202 of 204 countries and territories between 2000 and 2019. Interpretation Over the past 20 years, fertility rates have been dropping steadily and life expectancy has been increasing, with few exceptions. Much of this change follows historical patterns linking social and economic determinants, such as those captured by the GBD Socio-demographic Index, with demographic outcomes. More recently, several countries have experienced a combination of low fertility and stagnating improvement in mortality rates, pushing more populations into the late stages of the demographic transition. Tracking demographic change and the emergence of new patterns will be essential for global health monitoring. Copyright (C) 2020 The Author(s). Published by Elsevier Ltd.Peer reviewe
Global burden of 369 diseases and injuries in 204 countries and territories, 1990-2019: a systematic analysis for the Global Burden of Disease Study 2019
- Author
- Abbafati C
- Abbas KM
- Abbasi M
- Abbasi-Kangevari M
- Abbasifard M
- Abbastabar H
- Abd El Razek HM
- Abd El Razek MM
- Abd-Allah F
- Abdelalim A
- Abdollahi M
- Abdollahpour I
- Abdulkader RS
- Abdullah KH
- Abedi A
- Abedi P
- Abegaz KH
- Abolhassani H
- Abosetugn AE
- Aboyans V
- Abrams EM
- Abreu LG
- Abrigo MRM
- Abu Haimed AK
- Abu-Gharbieh E
- Abu-Raddad LJ
- Abualhasan A
- Abushouk AI
- Acebedo A
- Ackerman IN
- Adabi M
- Adair T
- Adamu AA
- Adebayo OM
- Adedeji IA
- Adekanmbi V
- Adelson JD
- Adeoye AM
- Adetokunboh OO
- Adham D
- Advani SM
- Afarideh M
- Afshari M
- Afshin A
- Agardh EE
- Agarwal G
- Agasthi P
- Agesa KM
- Aghaali M
- Aghamir SMK
- Agrawal A
- Ahmad T
- Ahmadi A
- Ahmadi K
- Ahmadi M
- Ahmadieh H
- Ahmadpour E
- Ahmed MB
- Aji B
- Akalu TY
- Akinyemi RO
- Akinyemiju T
- Akombi B
- Akunna CJ
- Al-Aly Z
- Al-Mekhlafi HM
- Al-Raddadi RM
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- Alam S
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- Alanzi TM
- Albertson SB
- Alcalde-Rabanal JE
- Alema NM
- Alemu BW
- Alemu YM
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- Alhassan RK
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- Ali S
- Alicandro G
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- Alinia C
- Alipour V
- Alizade H
- Aljunid SM
- Alla F
- Allebeck P
- Almadi MAH
- Almasi A
- Almasi-Hashiani A
- Almasri NA
- Almulhim AM
- Alonso J
- Altirkawi KA
- Alumran AK
- Alvis-Guzman N
- Alvis-Zakzuk NJ
- Amare AT
- Amare B
- Amini S
- Amini-Rarani M
- Aminorroaya A
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- Amit AML
- Amugsi DA
- Amul GGH
- Anbesu EW
- Ancuceanu R
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- Anderson JA
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- Androudi S
- Angus C
- Anjomshoa M
- Ansari F
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- Anvari D
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- Touvier M
- Tovani-Palone MR
- Traini E
- Tran BX
- Travillian R
- Trias-Llimos S
- Troeger CE
- Truelsen TC
- Tsai AC
- Tsatsakis A
- Tyrovolas S
- Uddin R
- Ullah I
- Ullah S
- Umeokonkwo CD
- Undurraga EA
- Unnikrishnan B
- Upadhyay E
- Uthman OA
- Vacante M
- Vaicekonyte R
- Vakilian A
- Valdez PR
- Valli A
- Van Donkelaar A
- Vardavas C
- Varughese S
- Vasankari TJ
- Vasconcelos AMN
- Vasseghian Y
- Veisani Y
- Velasquez IM
- Venketasubramanian N
- Vidale S
- Violante FS
- Vlassov V
- Vollset SE
- Vongpradith A
- Vos T
- Vu GT
- Vujcic IS
- Vukovic A
- Vukovic R
- Waheed Y
- Wallin MT
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- Wang F
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- Ward JL
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- Weintraub RG
- Weiss DJ
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- Werdecker A
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- Westerman R
- Whisnant JL
- Whiteford HA
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- Wickramasinghe ND
- Wiens KE
- Wijeratne T
- Wilner LB
- Wilson S
- Wiysonge CS
- Wojtyniak B
- Woldu G
- Wolfe CDA
- Wondmeneh TG
- Wondmieneh AB
- Wool EE
- Wozniak SS
- Wu A-M
- Wu C
- Wu J
- Wunrow HY
- Xie Y
- Xu G
- Xu R
- Yadgir S
- Yamada T
- Yamagishi K
- Yaminfirooz M
- Yano Y
- Yaya S
- Yazdi-Feyzabadi V
- Yearwood JA
- Yeheyis TY
- Yeshitila YG
- Yilgwan CS
- Yilma MT
- Yip P
- Yonemoto N
- Yoon S-J
- York HW
- Younis MZ
- Younker TP
- Yousefi B
- Yousefi Z
- Yousefifard M
- Yousefinezhadi T
- Yousuf AY
- Yu C
- Yu Y
- Yuan C-W
- Yuce D
- Yusefzadeh H
- Zadey S
- Zahabi SS
- Zaidi SS
- Zaki L
- Zaki MES
- Zakzuk J
- Zamani M
- Zamanian M
- Zandian H
- Zangeneh A
- Zarafshan H
- Zastrozhin MS
- Zewdie KA
- Zhang J
- Zhang Y
- Zhang Z-J
- Zhao JT
- Zhao X-JG
- Zhao Y
- Zheleva B
- Zheng P
- Zhou M
- Zhu C
- Ziapour A
- Zimsen SRM
- Zlavog BS
- Zodpey S
- Publication venue
- 'Elsevier BV'
- Publication date
- 17/10/2020
- Field of study
Five insights from the Global Burden of Disease Study 2019
- Author
- Abbafati C
- Abbas KM
- Abbasi M
- Abbasi-Kangevari M
- Abbasifard M
- Abbastabar H
- Abd El Razek HM
- Abd El Razek MM
- Abd-Allah F
- Abdelalim A
- Abdollahi M
- Abdollahpour I
- Abdulkader RS
- Abdullah KH
- Abedi A
- Abedi P
- Abegaz KH
- Abolhassani H
- Abosetugn AE
- Aboyans V
- Abrams EM
- Abreu LG
- Abrigo MRM
- Abu Haimed AK
- Abu-Gharbieh E
- Abu-Raddad LJ
- Abualhasan A
- Abushouk AI
- Acebedo A
- Ackerman IN
- Adabi M
- Adair T
- Adamu AA
- Adebayo OM
- Adedeji IA
- Adekanmbi V
- Adelson JD
- Adeoye AM
- Adetokunboh OO
- Adham D
- Advani SM
- Afarideh M
- Afshari M
- Afshin A
- Agardh EE
- Agarwal G
- Agasthi P
- Agesa KM
- Aghaali M
- Aghamir SMK
- Agrawal A
- Ahmad T
- Ahmadi A
- Ahmadi K
- Ahmadi M
- Ahmadieh H
- Ahmadpour E
- Ahmed MB
- Aji B
- Akalu TY
- Akinyemi RO
- Akinyemiju T
- Akombi B
- Akunna CJ
- Al-Aly Z
- Al-Mekhlafi HM
- Al-Raddadi RM
- Alahdab F
- Alam K
- Alam N
- Alam S
- Alam T
- Alanezi FM
- Alanzi TM
- Albertson SB
- Alcalde-Rabanal JE
- Alema NM
- Alemu BW
- Alemu YM
- Alhabib KF
- Alhassan RK
- Ali M
- Ali S
- Alicandro G
- Alijanzadeh M
- Alinia C
- Alipour V
- Alizade H
- Aljunid SM
- Alla F
- Allebeck P
- Almadi MAH
- Almasi A
- Almasi-Hashiani A
- Almasri NA
- Almulhim AM
- Alonso J
- Altirkawi KA
- Alumran AK
- Alvis-Guzman N
- Alvis-Zakzuk NJ
- Amare AT
- Amare B
- Amini S
- Amini-Rarani M
- Aminorroaya A
- Amiri F
- Amit AML
- Amugsi DA
- Amul GGH
- Anbesu EW
- Ancuceanu R
- Anderlini D
- Anderson JA
- Andrei CL
- Andrei T
- Androudi S
- Angus C
- Anjomshoa M
- Ansari F
- Ansari I
- Ansari-Moghaddam A
- Antonazzo IC
- Antonio CAT
- Antony CM
- Antriyandarti E
- Anvari D
- Anwer R
- Appiah SCY
- Arab-Zozani M
- Arabloo J
- Aravkin AY
- Arba AAK
- Aremu O
- Ariani F
- Aripov T
- Armoon B
- Arnlov J
- Arowosegbe OO
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- Arzani A
- Asaad M
- Asadi-Aliabadi M
- Asadi-Pooya AA
- Asgari S
- Asghari B
- Ashbaugh C
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- Atafar Z
- Athari SS
- Atnafu DD
- Atout MMW
- Atre SR
- Atteraya MS
- Ausloos F
- Ausloos M
- Avila-Burgos L
- Avokpaho EFGA
- Ayano G
- Ayanore MA
- Aynalem GL
- Aynalem YA
- Ayza MA
- Azari S
- Azarian G
- Azene ZN
- Azhar G
- Azzopardi PS
- Babaee E
- Badawi A
- Badiye AD
- Bagherzadeh M
- Bagli E
- Bahrami MA
- Baig AA
- Bairwa M
- Bakhshaei MH
- Bakhtiari A
- Bakkannavar SM
- Balachandran A
- Balakrishnan S
- Balalla S
- Balassyano S
- Baldasseroni A
- Bali AO
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- Ballew SH
- Balzi D
- Banach M
- Bandpei MAM
- Banerjee SK
- Banik PC
- Bannick MS
- Bante AB
- Bante SA
- Baraki AG
- Barboza MA
- Barker-Collo SL
- Barnighausen TW
- Barrero LH
- Barthelemy CM
- Barua L
- Barzegar A
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- Bassat Q
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- Bhutta ZA
- Bibi S
- Bicer BK
- Biehl MH
- Bijani A
- Bikbov B
- Bilano V
- Bin Sayeed MS
- Bin Zaman S
- Biondi A
- Birihane BM
- Bisanzio D
- Bisignano C
- Biswas RK
- Bitew H
- Bjorge T
- Bockarie MJ
- Bohlouli S
- Bohluli M
- Bojia HA
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- Brayne C
- Breitborde NJK
- Breitner S
- Brenner H
- Breusov AV
- Briant PS
- Briggs AM
- Briko AN
- Briko NI
- Britton GB
- Brugha T
- Bryazka D
- Buchbinder R
- Bumgarner BR
- Burkart K
- Burnett RT
- Busse R
- Butt ZA
- Caetano dos Santos FL
- Cahill LE
- Cahuana-Hurtado L
- Cai T
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- Camera LA
- Campos-Nonato IR
- Cao J
- Car J
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- Carrero JJ
- Carvalho F
- Castaldelli-Maia JM
- Castaneda-Orjuela CA
- Castelpietra G
- Castle CD
- Castro E
- Castro F
- Catala-Lopez F
- Causey K
- Cederroth CR
- Cercy KM
- Cerin E
- Chalek J
- Chandan JS
- Chang AR
- Chang AY
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- Chang K-L
- Charan J
- Charlson FJ
- Chattu VK
- Chaturvedi S
- Cherbuin N
- Chimed-Ochir O
- Chin KL
- Chirinos-Caceres JL
- Cho DY
- Choi J-YJ
- Christensen H
- Chu D-T
- Chung MT
- Chung S-C
- Cicuttini FM
- Ciobanu LG
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- Classen TKD
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- Collins EL
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- Compton K
- Conti S
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- Costa VM
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- Cowie BC
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- Crowe CS
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- Cunningham M
- D'Amico E
- da Silva DD
- Dahlawi SMA
- Dai H
- Dai H
- Damasceno AAM
- Damiani G
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- Daneshpajouhnejad P
- Dangel WJ
- Danielsson A-K
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- Darshan BB
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- Dean FE
- DeCleene NK
- Deen A
- Defo BK
- Degenhardt L
- DeLang M
- Dellavalle RP
- Demeke FM
- Demoz GT
- Demsie DG
- Denova-Gutierrez E
- Dereje ND
- Deribe K
- Dervenis N
- Desai R
- Desalew A
- Dessie GA
- Deuba K
- Dharmaratne SD
- Dhungana GP
- Dianatinasab M
- Diaz D
- Dichgans M
- Didarloo A
- Dingels ZV
- Dippenaar IN
- Dirac MA
- Djalalinia S
- Do HT
- Dokova K
- Doku DT
- Dolecek C
- Dolgert AJ
- Dorostkar F
- Doshi CP
- Doshi PP
- Doshmangir L
- Douiri A
- Doxey MC
- Doyle KE
- Driscoll TR
- Dubljanin E
- Dunachie SJ
- Duncan BB
- Duraes AR
- Eagan AW
- Ebrahimi H
- Edvardsson D
- Effiong A
- Ehrlich JR
- El Nahas N
- El Sayed I
- El Tantawi M
- El-Jaafary SI
- Elbarazi I
- Elgendy IY
- Elhabashy HR
- Elsharkawy A
- Elyazar IRF
- Emamian MH
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- Erskine HE
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- Eskandarieh S
- Esmaeilnejad S
- Esmaeilzadeh F
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- Etisso AE
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- Fanzo J
- Farag T
- Farahmand M
- Faraj A
- Faraon EJA
- Fareed M
- Faridnia R
- Farinha CSES
- Farioli A
- Faris PS
- Faro A
- Faruque M
- Farzadfar F
- Fattahi N
- Fazaeli AA
- Fazlzadeh M
- Feigin VL
- Feldman R
- Fereshtehnejad S-M
- Fernandes E
- Ferrara G
- Ferrara P
- Ferrari AJ
- Ferreira ML
- Feyissa GT
- Filip I
- Fischer F
- Fisher JL
- Fitzgerald R
- Flohr C
- Flor LS
- Foigt NA
- Folayan MO
- Fomenkov AA
- Force LM
- Fornari C
- Forooshani ZSD
- Foroutan M
- Fox JT
- Francis JM
- Frank TD
- Franklin RC
- Freitas M
- Fu W
- Fukumoto T
- Fukutaki K
- Fuller JE
- Fullman N
- Furtado JM
- Gad MM
- Gaidhane AM
- Gakidou E
- Galles NC
- Gallus S
- Gamkrelidze A
- Garcia-Basteiro AL
- Gardner WM
- Geberemariyam BS
- Gebrehiwot AM
- Gebremedhin KB
- Gebremeskel GG
- Gebremeskel LG
- Gebresillassie BM
- Gebreslassie AAAA
- Gela JD
- Geramo YCD
- Geremew A
- Gesesew HA
- Gething PW
- Gezae KE
- Ghadimi M
- Ghadiri K
- Ghaffarifar F
- Ghafourifard M
- Ghajar A
- Ghamari F
- Ghashghaee A
- Ghiasvand H
- Ghith N
- Gholamian A
- Ghosh R
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- Gilani SA
- Gill PS
- Gill TK
- Gillum RF
- Ginawi IA
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- Gnedovskaya EV
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- Guled RA
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- Jayatilleke AU
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- Publication venue
- Publication date
- 01/01/2020
- Field of study
The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2019 provides a rules-based synthesis of the available evidence on levels and trends in health outcomes, a diverse set of risk factors, and health system responses. GBD 2019 covered 204 countries and territories, as well as first administrative level disaggregations for 22 countries, from 1990 to 2019. Because GBD is highly standardised and comprehensive, spanning both fatal and non-fatal outcomes, and uses a mutually exclusive and collectively exhaustive list of hierarchical disease and injury causes, the study provides a powerful basis for detailed and broad insights on global health trends and emerging challenges. GBD 2019 incorporates data from 281 586 sources and provides more than 3.5 billion estimates of health outcome and health system measures of interest for global, national, and subnational policy dialogue. All GBD estimates are publicly available and adhere to the Guidelines on Accurate and Transparent Health Estimate Reporting. From this vast amount of information, five key insights that are important for health, social, and economic development strategies have been distilled. These insights are subject to the many limitations outlined in each of the component GBD capstone papers.Peer reviewe
Mortality from gastrointestinal congenital anomalies at 264 hospitals in 74 low-income, middle-income, and high-income countries: a multicentre, international, prospective cohort study
- Author
- Abantanga FA
- Abatli SJ
- Abbas W
- Abbo O
- Abd Elmenam M
- Abd Razak RB
- Abdelbaqi R
- Abdelhady DS
- Abdelhafez MOM
- Abdelhamid SS
- Abdelmaksoud S
- Abdelmoumen R
- Abdelmutalib F
- Abdul-Mumin A
- Abduljawad FM
- Abdullah F
- Abdulraheem N
- Abdulrahman A
- Abdulsalam MA
- Abdunomonovich DA
- Abib SDCV
- Aboelela A
- Abouheba M
- Abrahamsson K
- Abu Ajwa AE
- Abu Al-saleem HSH
- Abu Alamrain AA
- Abu Bakar AH
- Abu Farha MS
- Abu Jamie N
- Abu Jamie YMK
- Abu Jayyab M
- Abu Mayaleh A
- Abu Shiha E
- Abu Za'nouneh FJ
- Abu-Nejmah F
- Abuajaila A
- Abuattaya AA
- Abubakar AM
- Abueideh A
- Abuhayyeh HA
- Abuhlega MA
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- Abumunshar AA
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- Adams S
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- Adawi I
- Adawi S
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- Adegboyega R
- Ademuyiwa A
- Adesanya O
- Adhiwidjaja CF
- Adofo-Ansong N
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- Ajao EA
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- Zurikat RO
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- Publication venue
- ELSEVIER SCIENCE INC
- Publication date
- 24/07/2021
- Field of study
Background: Congenital anomalies are the fifth leading cause of mortality in children younger than 5 years globally. Many gastrointestinal congenital anomalies are fatal without timely access to neonatal surgical care, but few studies have been done on these conditions in low-income and middle-income countries (LMICs). We compared outcomes of the seven most common gastrointestinal congenital anomalies in low-income, middle-income, and high-income countries globally, and identified factors associated with mortality. // Methods: We did a multicentre, international prospective cohort study of patients younger than 16 years, presenting to hospital for the first time with oesophageal atresia, congenital diaphragmatic hernia, intestinal atresia, gastroschisis, exomphalos, anorectal malformation, and Hirschsprung's disease. Recruitment was of consecutive patients for a minimum of 1 month between October, 2018, and April, 2019. We collected data on patient demographics, clinical status, interventions, and outcomes using the REDCap platform. Patients were followed up for 30 days after primary intervention, or 30 days after admission if they did not receive an intervention. The primary outcome was all-cause, in-hospital mortality for all conditions combined and each condition individually, stratified by country income status. We did a complete case analysis. // Findings: We included 3849 patients with 3975 study conditions (560 with oesophageal atresia, 448 with congenital diaphragmatic hernia, 681 with intestinal atresia, 453 with gastroschisis, 325 with exomphalos, 991 with anorectal malformation, and 517 with Hirschsprung's disease) from 264 hospitals (89 in high-income countries, 166 in middle-income countries, and nine in low-income countries) in 74 countries. Of the 3849 patients, 2231 (58·0%) were male. Median gestational age at birth was 38 weeks (IQR 36â39) and median bodyweight at presentation was 2·8 kg (2·3â3·3). Mortality among all patients was 37 (39·8%) of 93 in low-income countries, 583 (20·4%) of 2860 in middle-income countries, and 50 (5·6%) of 896 in high-income countries (p<0·0001 between all country income groups). Gastroschisis had the greatest difference in mortality between country income strata (nine [90·0%] of ten in low-income countries, 97 [31·9%] of 304 in middle-income countries, and two [1·4%] of 139 in high-income countries; pâ€0·0001 between all country income groups). Factors significantly associated with higher mortality for all patients combined included country income status (low-income vs high-income countries, risk ratio 2·78 [95% CI 1·88â4·11], p<0·0001; middle-income vs high-income countries, 2·11 [1·59â2·79], p<0·0001), sepsis at presentation (1·20 [1·04â1·40], p=0·016), higher American Society of Anesthesiologists (ASA) score at primary intervention (ASA 4â5 vs ASA 1â2, 1·82 [1·40â2·35], p<0·0001; ASA 3 vs ASA 1â2, 1·58, [1·30â1·92], p<0·0001]), surgical safety checklist not used (1·39 [1·02â1·90], p=0·035), and ventilation or parenteral nutrition unavailable when needed (ventilation 1·96, [1·41â2·71], p=0·0001; parenteral nutrition 1·35, [1·05â1·74], p=0·018). Administration of parenteral nutrition (0·61, [0·47â0·79], p=0·0002) and use of a peripherally inserted central catheter (0·65 [0·50â0·86], p=0·0024) or percutaneous central line (0·69 [0·48â1·00], p=0·049) were associated with lower mortality. // Interpretation: Unacceptable differences in mortality exist for gastrointestinal congenital anomalies between low-income, middle-income, and high-income countries. Improving access to quality neonatal surgical care in LMICs will be vital to achieve Sustainable Development Goal 3.2 of ending preventable deaths in neonates and children younger than 5 years by 2030
Muon reconstruction and identification efficiency in ATLAS using the full Run 2 pp collision data set at \sqrt{s}=13 TeV
- Author
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- Abbott B
- Abbott DC
- Abeling K
- Abhayasinghe DK
- Abidi SH
- AbouZeid OS
- Abraham NL
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- Acharya BS
- Achkar B
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- Adamczyk L
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- Adelman J
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- Ahnen JV
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- Yildiz HD
- Yin P
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- Yoshihara K
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- Yue X
- Zaazoua M
- Zabinski B
- Zacharis G
- Zaffaroni E
- Zahreddine J
- Zaitsev AM
- Zakareishvili T
- Zakharchuk N
- Zambito S
- Zanzi D
- Zeissner SV
- Zeitnitz C
- Zemaityte G
- Zeng JC
- Zenin O
- Zenis T
- Zerwas D
- Zgubic M
- Zhang B
- Zhang DF
- Zhang G
- Zhang J
- Zhang K
- Zhang L
- Zhang L
- Zhang M
- Zhang R
- Zhang S
- Zhang X
- Zhang X
- Zhang Y
- Zhang Z
- Zhang Z
- Zhao P
- Zhao Y
- Zhao Z
- Zhemchugov A
- Zheng Z
- Zhong D
- Zhou B
- Zhou C
- Zhou H
- Zhou M
- Zhou N
- Zhou Y
- Zhu C
- Zhu CG
- Zhu H
- Zhu HL
- Zhu J
- Zhu Y
- Zhuang X
- Zhukov K
- Zhulanov V
- Zieminska D
- Zimine NI
- Zimmermann S
- Zinonos Z
- Ziolkowski M
- Zivkovic L
- Zobernig G
- Zoccoli A
- Zoch K
- Zorbas TG
- Zou R
- Zwalinski L
- Publication venue
- 'Springer Fachmedien Wiesbaden GmbH'
- Publication date
- 01/01/2021
- Field of study
This article documents the muon reconstruction and identification efficiency obtained by the ATLAS experiment for 139 \hbox {fb}^{-1} of pp collision data at \sqrt{s}=13 TeV collected between 2015 and 2018 during Run 2 of the LHC. The increased instantaneous luminosity delivered by the LHC over this period required a reoptimisation of the criteria for the identification of prompt muons. Improved and newly developed algorithms were deployed to preserve high muon identification efficiency with a low misidentification rate and good momentum resolution. The availability of large samples of Z\rightarrow \mu \mu and J/\psi \rightarrow \mu \mu decays, and the minimisation of systematic uncertainties, allows the efficiencies of criteria for muon identification, primary vertex association, and isolation to be measured with an accuracy at the per-mille level in the bulk of the phase space, and up to the percent level in complex kinematic configurations. Excellent performance is achieved over a range of transverse momenta from 3 GeV to several hundred GeV, and across the full muon detector acceptance of |\eta |<2.7
Corrigendum to "Search for flavour-changing neutral-current couplings between the top quark and the photon with the ATLAS detector at âs=13 TeV" (Physics Letters B, 842 (2023), 137379)
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- Ridel M
- Rieck P
- Riedler P
- Rijssenbeek M
- Rimoldi A
- Rimoldi M
- Rinaldi L
- Rinn Tt
- Rinnagel Mp
- Ripellino G
- Riu I
- Rivadeneira P
- Rivera Vergara Jc
- Rizatdinova F
- Rizvi E
- Rizzi C
- Roberts Ba
- Roberts Br
- Robertson Sh
- Robin M
- Robinson D
- Robles Gajardo Cm
- Robles Manzano M
- Robson A
- Rocchi A
- Roda C
- Rodriguez Bosca S
- Rodriguez Garcia Y
- Rodriguez Rodriguez A
- RodriÌguez Vera Am
- Roe S
- Roemer Jt
- Roepe-Gier Ar
- Roggel J
- Rojas Ra
- Roland B
- Roland Cpa
- Roloff J
- Romaniouk A
- Romano M
- Romero Hernandez Ac
- Rompotis N
- Roos L
- Rosati S
- Rosser Bj
- Rossi E
- Rossi E
- Rossi Lp
- Rossini L
- Rosten R
- Rotaru M
- Rottler B
- Rousseau D
- Rousso D
- Rovelli G
- Roy A
- Rozanov A
- Rozen Y
- Ruan X
- Rubio Jimenez A
- Ruby Aj
- Ruggeri Ta
- Ruiz-Martinez A
- Rummler A
- Rurikova Z
- Rusakovich Na
- Russell Hl
- Rutherfoord Jp
- RuÌhr F
- RuÌttinger Em
- Rybacki K
- Rybar M
- Rye Eb
- Ryzhov A
- RĂžhne O
- Sabater Iglesias Ja
- Sabatini P
- Sabetta L
- Sadrozinski Hf
- Safai Tehrani F
- Safarzadeh Samani B
- Safdari M
- Saha S
- Sahinsoy M
- Saimpert M
- Saito M
- Saito T
- Salamani D
- Salamanna G
- Salnikov A
- Salt J
- Salvador Salas A
- Salvatore D
- Salvatore F
- Salzburger A
- Sammel D
- Sampsonidis D
- Sampsonidou D
- Sanchez Pineda A
- Sanchez Sebastian V
- Sandaker H
- Sander Co
- Sandesara Ja
- Sandhoff M
- Sandoval C
- Sankey Dpc
- Sansoni A
- Santoni C
- Santos H
- Santpur Sn
- Santra A
- Saoucha Ka
- Saraiva Jg
- Sardain J
- Sasaki O
- Sato K
- Sauer C
- Sauerburger F
- Sauvan E
- Savard P
- Sawada R
- Sawyer C
- Sawyer L
- Sayago Galvan I
- SaÌnchez J
- Sbarra C
- Sbrizzi A
- Scanlon T
- Schaarschmidt J
- Schacht P
- Schaefer D
- Schaffer Ac
- Schaile D
- Schamberger Rd
- Schanet E
- Scharf C
- SchaÌfer U
- Schegelsky Va
- Scheirich D
- Schenck F
- Schernau M
- Scheulen C
- Schiavi C
- Schillaci Zm
- Schioppa Ej
- Schioppa M
- Schlag B
- Schleicher Ke
- Schlenker S
- Schmieden K
- Schmitt C
- Schmitt S
- Schoeffel L
- Schoening A
- Scholer Pg
- Schopf E
- Schott M
- Schovancova J
- Schramm S
- Schroeder F
- Schultz-Coulon H
- Schumacher M
- Schumm Ba
- Schune P
- Schwartzman A
- Schwarz Ta
- Schwemling P
- Schwienhorst R
- Sciandra A
- Sciolla G
- Scuri F
- Scutti F
- Sebastiani Cd
- Sedlaczek K
- Seema P
- Seidel Sc
- Seiden A
- Seidlitz Bd
- Seiss T
- Seitz C
- Seixas Jm
- Sekhniaidze G
- Sekula Sj
- Selem L
- Semprini-Cesari N
- Sen S
- Senthilkumar V
- Serin L
- Serkin L
- Sessa M
- Severini H
- Sevova S
- Sforza F
- Sfyrla A
- Shabalina E
- Shaheen R
- Shahinian Jd
- Shaikh Nw
- Shaked Renous D
- Shan Ly
- Shapiro M
- Sharma A
- Sharma As
- Sharma P
- Sharma S
- Shatalov Pb
- Shaw K
- Shaw Sm
- Sherwood P
- Shi L
- Shimmin Co
- Shimogama Y
- Shinner Jd
- Shipsey Ipj
- Shirabe S
- Shiyakova M
- Shlomi J
- Shochet Mj
- Shojaii J
- Shope Dr
- Shrestha S
- Shrif Em
- Shroff Mj
- Sicho P
- Sickles Am
- Sideras Haddad E
- Sidiropoulou O
- Sidoti A
- Siegert F
- Sijacki D
- Sikora R
- Sili F
- Silva Oliveira Mv
- Silva Jm
- Silverstein Sb
- Simion S
- Simoniello R
- Simpson El
- Simpson Nd
- Simsek S
- Sindhu S
- Sinervo P
- Sinetckii V
- Singh S
- Singh S
- Sinha S
- Sinha S
- Sioli M
- Siral I
- Sivoklokov Sy
- SjoÌlin J
- Skaf A
- Skorda E
- Skubic P
- Slawinska M
- Smakhtin V
- Smart Bh
- Smiesko J
- Smirnov Sy
- Smirnov Y
- Smirnova Ln
- Smirnova O
- Smith Ea
- Smith Ha
- Smith Jl
- Smith R
- Smizanska M
- Smolek K
- Smykiewicz A
- Snesarev Aa
- Snoek Hl
- Snyder S
- Sobie R
- Soffer A
- Solans Sanchez Ca
- Soldatov Ey
- Soldevila U
- Solodkov Aa
- Solomon S
- Soloshenko A
- Solovieva K
- Solovyanov Ov
- Solovyev V
- Sommer P
- Sonay A
- Song Wy
- Sopczak A
- Sopio Al
- Sopkova F
- Sothilingam V
- Sottocornola S
- Soualah R
- Soumaimi Z
- South D
- Spagnolo S
- Spalla M
- SpanoÌ F
- Sperlich D
- Spigo G
- Spina M
- Spinali S
- Spiteri Dp
- Spousta M
- Staats Ej
- Stabile A
- Stamen R
- Stamenkovic M
- Stampekis A
- Standke M
- Stanecka E
- Stanislaus B
- Stanitzki Mm
- Stankaityte M
- Stapf B
- Starchenko Ea
- Stark Gh
- Stark J
- Starko Dm
- Staroba P
- Starovoitov P
- Staszewski R
- Stavropoulos G
- StaÌrz S
- Steentoft J
- Steinberg P
- Steinhebel Al
- Stelzer B
- Stelzer Hj
- Stelzer-Chilton O
- Stenzel H
- Stevenson Tj
- Stewart Ga
- Stockton Mc
- Stoicea G
- Stolarski M
- Stonjek S
- Straessner A
- Strandberg J
- Strandberg S
- Strauss M
- Strebler T
- Strizenec P
- Strom Dm
- Strom Lr
- Stroynowski R
- StroÌhmer R
- Strubig A
- Stucci Sa
- Stugu B
- Stupak J
- Styles Na
- Su D
- Su S
- Su W
- Su X
- Sugizaki K
- Sulin Vv
- Sullivan Mj
- Sultan Dms
- Sultanaliyeva L
- Sultansoy S
- Sumida T
- Sun S
- Sun S
- Sunneborn Gudnadottir O
- Sutton Mr
- Svatos M
- Swiatlowski M
- Swirski T
- Sykora I
- Sykora M
- Sykora T
- Ta D
- Tackmann K
- Taffard A
- Tafirout R
- Tafoya Vargas Js
- Taibah Rhm
- Takashima R
- Takeda K
- Takeva Ep
- Takubo Y
- Talby M
- Talyshev Aa
- Tam Kc
- Tamir Nm
- Tanaka A
- Tanaka J
- Tanaka R
- Tanasini M
- Tang J
- Tao Z
- Tapia Araya S
- Tapprogge S
- Tarek Abouelfadl Mohamed A
- Tarem S
- Tariq K
- Tarna G
- Tartarelli Gf
- Tas P
- Tasevsky M
- Tassi E
- Tate Ac
- Tateno G
- Tayalati Y
- Taylor Gn
- Taylor W
- Teagle H
- Tee As
- Teixeira De Lima R
- Teixeira-Dias P
- Teoh Jj
- Terashi K
- Terron J
- Terzo S
- Testa M
- Teuscher Rj
- Themistokleous N
- Theveneaux-Pelzer T
- Thielmann O
- Thomas Dw
- Thomas Jp
- Thompson Ea
- Thompson Pd
- Thomson E
- Thorpe Ej
- Tian Y
- Tikhomirov V
- Tikhonov Ya
- Timoshenko S
- Ting Exl
- Tipton P
- Tisserant S
- Tlou Sh
- Tnourji A
- Todome K
- Todorova-Nova S
- Todt S
- Togawa M
- Tojo J
- TokaÌr S
- Tokushuku K
- Tombs R
- Tomoto M
- Tompkins L
- Tornambe P
- Torrence E
- Torres H
- TorroÌ Pastor E
- Toscani M
- Tosciri C
- Tovey Dr
- Traeet A
- Trandafir Is
- Trefzger T
- Tricoli A
- Trigger Im
- Trincaz-Duvoid S
- Trischuk Da
- TrocmeÌ B
- Trofymov A
- Troncon C
- Truong L
- Trzebinski M
- Trzupek A
- Tsai F
- Tsai M
- Tsiamis A
- Tsiareshka Pv
- Tsirigotis A
- Tsiskaridze V
- Tskhadadze Eg
- Tsopoulou M
- Tsujikawa Y
- Tsukerman Ii
- Tsulaia V
- Tsuno S
- Tsur O
- Tsybychev D
- Tu Y
- Tudorache A
- Tudorache V
- Tuna An
- Turchikhin S
- Turk Cakir I
- Turra R
- Tuts Pm
- Tzamarias S
- Tzanis P
- Tzovara E
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- Ulloa Poblete Pa
- Unal G
- Unal M
- Undrus A
- Unel G
- Uno K
- Urban J
- Urquijo P
- Usai G
- Ushioda R
- Usman M
- Uysal Z
- Vacek V
- Vachon B
- Vadla Koh
- Vafeiadis T
- Valderanis C
- Valdes Santurio E
- Valente M
- Valentinetti S
- Valero A
- Vallier A
- Valls Ferrer Ja
- Van Daalen Tr
- Van Gemmeren P
- Van Stroud S
- Van Vulpen I
- Vanadia M
- Vandelli W
- Vandenbroucke M
- Vandewall Er
- Vannicola D
- Vannoli L
- Vari R
- Varnes Ew
- Varni C
- Varol T
- Varouchas D
- Varriale L
- Varvell Ke
- Vasile Me
- Vaslin L
- Vasquez Ga
- Vazeille F
- Vazquez Furelos D
- Vazquez Schroeder T
- Veatch J
- Vecchio V
- Veen Mj
- Veliscek I
- Veloce Lm
- Veloso F
- Veneziano S
- Ventura A
- Verbytskyi A
- Verducci M
- Vergis C
- Verissimo De Araujo M
- Verkerke W
- Vermeulen Jc
- Vernieri C
- Verschuuren Pj
- Vessella M
- Vesterbacka Ml
- Vetterli Mc
- Vgenopoulos A
- Viaux Maira N
- Vickey Boeriu Oe
- Vickey T
- Viehhauser Gha
- Vigani L
- Villa M
- Villaplana Perez M
- Villhauer Em
- Vilucchi E
- Vincter Mg
- Virdee Gs
- Vishwakarma A
- Vittori C
- Vivarelli I
- Vladimirov V
- Voevodina E
- Vogel F
- Vokac P
- Von Ahnen J
- Von Toerne E
- Vormwald B
- Vorobel V
- Vorobev K
- Vos M
- Vossebeld Jh
- Vozak M
- Vozdecky L
- Vranjes Milosavljevic M
- Vranjes N
- Vreeswijk M
- Vuillermet R
- Vujinovic O
- Vukotic I
- Wada S
- Wagner C
- Wagner W
- Wahdan S
- Wahlberg H
- Wakasa R
- Wakida M
- Walbrecht Vm
- Walder J
- Walker R
- Walkowiak W
- Wang Am
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- Wang T
- Wang Wt
- Wang Wx
- Wang X
- Wang X
- Wang X
- Wang Y
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- Wang Z
- Wang Z
- Wang Z
- Warburton A
- Ward Rj
- Warrack N
- Watson At
- Watson Mf
- Watts G
- Waugh Bm
- Webb Af
- Weber C
- Weber Ms
- Weber Sa
- Weber Sm
- Wei C
- Wei Y
- Weidberg Ar
- Weingarten J
- Weirich M
- Weiser C
- Wells Cj
- Wenaus T
- Wendland B
- Wengler T
- Wenke Ns
- Wermes N
- Wessels M
- Whalen K
- Wharton Am
- White A
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- White Mj
- Whiteson D
- Wickremasinghe L
- Wiedenmann W
- Wiel C
- Wielers M
- Wieseotte N
- Wiglesworth C
- Wiik-Fuchs Lam
- Wilbern Dj
- Wilkens Hg
- Williams Dm
- Williams Hh
- Williams S
- Willocq S
- Windischhofer Pj
- Winklmeier F
- Winter Bt
- Wittgen M
- Wobisch M
- Wolf A
- Wollrath J
- Wolter Mw
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- Wong Vws
- Wongel Af
- Worm Sd
- Wosiek Bk
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- Wyatt Tr
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- Xiotidis I
- Xu D
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- Yacoob S
- Yamaguchi N
- Yamaguchi Y
- Yamauchi H
- Yamazaki T
- Yamazaki Y
- Yan J
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- Yao W
- Yap Yc
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- Ye X
- Yeletskikh I
- Yexley Mr
- Yin P
- Yorita K
- Young C
- Young Cjs
- Yuan M
- Yuan R
- Yue X
- Zaazoua M
- Zabinski B
- Zaid E
- Zakareishvili T
- Zakharchuk N
- Zambito S
- Zang J
- Zanzi D
- Zaplatilek O
- Zeitnitz C
- ZeiĂner Sv
- Zeng Jc
- Zenger Dt
- Zenin O
- Zenz S
- Zerradi S
- Zerwas D
- Zhang B
- Zhang Df
- Zhang G
- Zhang J
- Zhang K
- Zhang L
- Zhang R
- Zhang S
- Zhang T
- Zhang X
- Zhang X
- Zhang Z
- Zhao H
- Zhao P
- Zhao T
- Zhao Y
- Zhao Z
- Zhemchugov A
- Zheng Z
- Zhong D
- Zhou B
- Zhou C
- Zhou H
- Zhou N
- Zhou Y
- Zhu C
- Zhu Cg
- Zhu H
- Zhu Hl
- Zhu J
- Zhu Y
- Zhuang X
- Zhukov K
- Zhulanov V
- Zimine Ni
- Zinsser J
- Ziolkowski M
- Zoccoli A
- Zoch K
- Zorbas Tg
- Zormpa O
- Zou W
- Zwalinski L
- ZÌenisÌ T
- ZÌivkovicÌ L
- Publication venue
- ELSEVIER
- Publication date
- 01/01/2023
- Field of study
Configuration and performance of the ATLAS b-jet triggers in Run 2
- Author
- Aad G
- Abbott B
- Abbott DC
- Abed Abud A
- Abeling K
- Abhayasinghe DK
- Abidi SH
- AbouZeid OS
- Abraham NL
- Abramowicz H
- Abreu H
- Abulaiti Y
- Acharya BS
- Achkar B
- Adam Bourdarios C
- Adam L
- Adamczyk L
- Adamek L
- Adelman J
- Adiguzel A
- Adorni S
- Adye T
- Affolder AA
- Afik Y
- Agapopoulou C
- Agaras MN
- Aggarwal A
- Agheorghiesei C
- Aguilar-Saavedra JA
- Ahmad A
- Ahmadov F
- Ahmed WS
- Ai X
- Aielli G
- Akatsuka S
- Akbiyik M
- Akesson TPA
- Akilli E
- Akimov AV
- Al Khoury K
- Alberghi GL
- Albert J
- Alconada Verzini MJ
- Alderweireldt S
- Aleksa M
- Aleksandrov IN
- Alexa C
- Alexopoulos T
- Alfonsi A
- Alfonsi F
- Alhroob M
- Ali B
- Ali S
- Aliev M
- Alimonti G
- Alison J
- Allaire C
- Allbrooke BMM
- Allport PP
- Aloisio A
- Alonso F
- Alpigiani C
- Alunno Camelia E
- Alvarez Estevez M
- Alviggi MG
- Amaral Coutinho Y
- Ambler A
- Ambroz L
- Amelung C
- Amidei D
- Amor Dos Santos SP
- Amoroso S
- Amrouche CS
- Anastopoulos C
- Andari N
- Andeen T
- Anders JK
- Andrean SY
- Andreazza A
- Andrei V
- Anelli CR
- Angelidakis S
- Angerami A
- Anisenkov AV
- Annovi A
- Antel C
- Anthony MT
- Antipov E
- Antonelli M
- Antrim DJA
- Anulli F
- Aoki M
- Aparisi Pozo JA
- Aparo MA
- Aperio Bella L
- Aranzabal N
- Araujo Ferraz V
- Arcangeletti C
- Arce ATH
- Arguin J-F
- Argyropoulos S
- Arling J-H
- Armbruster AJ
- Armstrong A
- Arnaez O
- Arnold H
- Arrubarrena Tame ZP
- Artoni G
- Asada H
- Asai K
- Asai S
- Asawatavonvanich T
- Asbah NA
- Asimakopoulou EM
- Asquith L
- Assahsah J
- Assamagan K
- Astalos R
- Atkin RJ
- Atkinson M
- Atlay NB
- Atmani H
- Atmasiddha PA
- Augsten K
- Austrup VA
- Avolio G
- Ayoub MK
- Azuelos G
- Babal D
- Bachacou H
- Bachas K
- Backman F
- Bagnaia P
- Bahrasemani H
- Bailey AJ
- Bailey VR
- Baines JT
- Bakalis C
- Baker OK
- Bakker PJ
- Bakos E
- Bakshi Gupta D
- Balaji S
- Balasubramanian R
- Baldin EM
- Balek P
- Balli F
- Balunas WK
- Balz J
- Banas E
- Bandieramonte M
- Bandyopadhyay A
- Barak L
- Barbe WM
- Barberio EL
- Barberis D
- Barbero M
- Barbour G
- Barillari T
- Barisits M-S
- Barkeloo J
- Barklow T
- Barnett BM
- Barnett RM
- Barnovska-Blenessy Z
- Baroncelli A
- Barone G
- Barr AJ
- Barranco Navarro L
- Barreiro Guimaraes da Costa J
- Barreiro F
- Barron U
- Barsov S
- Bartels F
- Bartoldus R
- Bartolini G
- Barton AE
- Bartos P
- Basalaev A
- Basan A
- Bassalat A
- Basso MJ
- Basson CR
- Bates RL
- Batlamous S
- Batley JR
- Batool B
- Battaglia M
- Bauce M
- Bauer F
- Bauer P
- Bawa HS
- Bayirli A
- Beacham JB
- Beau T
- Beauchemin PH
- Becherer F
- Bechtle P
- Beck HP
- Becker K
- Becot C
- Beddall AJ
- Bednyakov VA
- Bee CP
- Beermann TA
- Begalli M
- Begel M
- Behera A
- Behr JK
- Beisiegel F
- Belfkir M
- Bella G
- Bellagamba L
- Bellerive A
- Bellos P
- Beloborodov K
- Belotskiy K
- Belyaev NL
- Benchekroun D
- Benekos N
- Benhammou Y
- Benjamin DP
- Benoit M
- Bensinger JR
- Bentvelsen S
- Beresford L
- Beretta M
- Berge D
- Bergeaas Kuutmann E
- Berger N
- Bergmann B
- Bergsten LJ
- Beringer J
- Berlendis S
- Bernardi G
- Bernius C
- Bernlochner FU
- Berry T
- Berta P
- Berthold A
- Bertram IA
- Bessidskaia Bylund O
- Bethke S
- Betti A
- Bevan AJ
- Bhatta S
- Bhattacharya DS
- Bhattarai P
- Bhopatkar VS
- Bi R
- Bianchi RM
- Biebel O
- Biedermann D
- Bielski R
- Bierwagen K
- Biesuz NV
- Biglietti M
- Billoud TRV
- Bindi M
- Bingul A
- Bini C
- Biondi S
- Birch-Sykes CJ
- Birman M
- Bisanz T
- Biswal JP
- Biswas D
- Bitadze A
- Bittrich C
- Bjorke K
- Blazek T
- Bloch I
- Blocker C
- Blue A
- Blumenschein U
- Blumenthal J
- Bobbink GJ
- Bobrovnikov VS
- Bogavac D
- Bogdanchikov AG
- Bohm C
- Boisvert V
- Bokan P
- Bold T
- Bomben M
- Bona M
- Bonilla JS
- Boonekamp M
- Booth CD
- Borbely AG
- Borecka-Bielska HM
- Borgna LS
- Borissov G
- Bortoletto D
- Boscherini D
- Bosman M
- Bossio Sola JD
- Bouaouda K
- Boudreau J
- Bouhova-Thacker EV
- Boumediene D
- Bouquet R
- Boveia A
- Boyd J
- Boye D
- Boyko IR
- Bozson AJ
- Bracinik J
- Brahimi N
- Brandt G
- Brandt O
- Braren F
- Brau B
- Brau JE
- Breaden Madden WD
- Brendlinger K
- Brener R
- Brenner L
- Brenner R
- Bressler S
- Brickwedde B
- Briglin DL
- Britton D
- Britzger D
- Brock I
- Brock R
- Brooijmans G
- Brooks WK
- Brost E
- Bruckman de Renstrom PA
- Brueers B
- Bruncko D
- Bruni A
- Bruni G
- Bruschi M
- Bruscino N
- Bryngemark L
- Buanes T
- Buat Q
- Buchholz P
- Buckley AG
- Budagov IA
- Buescher V
- Bugge MK
- Bulekov O
- Bullard BA
- Burch TJ
- Burdin S
- Burgard CD
- Burger AM
- Burghgrave B
- Burr JTP
- Burton CD
- Burzynski JC
- Buschmann E
- Bussey PJ
- Butler JM
- Buttar CM
- Butterworth JM
- Buttinger W
- Buxo Vazquez CJ
- Buzykaev AR
- Cabras G
- Cabrera Urban S
- Caforio D
- Cai H
- Cairo VMM
- Cakir O
- Calace N
- Calafiura P
- Calderini G
- Calfayan P
- Callea G
- Caloba LP
- Caltabiano A
- Calvente Lopez S
- Calvet D
- Calvet S
- Calvet TP
- Calvetti M
- Camacho Toro R
- Camarda S
- Camarero Munoz D
- Camarri P
- Camerlingo MT
- Cameron D
- Camincher C
- Campanelli M
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- Zhang X
- Zhang X
- Zhang Y
- Zhang Z
- Zhao P
- Zhao Y
- Zhao Z
- Zhemchugov A
- Zheng Z
- Zhong D
- Zhou B
- Zhou C
- Zhou H
- Zhou M
- Zhou N
- Zhou Y
- Zhu C
- Zhu CG
- Zhu H
- Zhu HL
- Zhu J
- Zhu Y
- Zhuang X
- Zhukov K
- Zhulanov V
- Zieminska D
- Zimine NI
- Zimmermann S
- Zinonos Z
- Ziolkowski M
- Zivkovic L
- Zoccoli A
- Zoch K
- Zorbas TG
- Zou R
- Zou W
- Zwalinski L
- Publication venue
- 'Springer Fachmedien Wiesbaden GmbH'
- Publication date
- 01/12/2021
- Field of study
Several improvements to the ATLAS triggers used to identify jets containing b-hadrons (b-jets) were implemented for data-taking during Run 2 of the Large Hadron Collider from 2016 to 2018. These changes include reconfiguring the b-jet trigger software to improve primary-vertex finding and allow more stable running in conditions with high pile-up, and the implementation of the functionality needed to run sophisticated taggers used by the offline reconstruction in an online environment. These improvements yielded an order of magnitude better light-flavour jet rejection for the same b-jet identification efficiency compared to the performance in Run 1 (2011â2012). The efficiency to identify b-jets in the trigger, and the conditional efficiency for b-jets that satisfy offline b-tagging requirements to pass the trigger are also measured. Correction factors are derived to calibrate the b-tagging efficiency in simulation to match that observed in data. The associated systematic uncertainties are substantially smaller than in previous measurements. In addition, b-jet triggers were operated for the first time during heavy-ion data-taking, using dedicated triggers that were developed to identify semileptonic b-hadron decays by selecting events with geometrically overlapping muons and jets
The ATLAS inner detector trigger performance in pp collisions at 13 TeV during LHC Run 2
- Author
- Aad G
- Abbott B
- Abbott DC
- Abeling K
- Abhayasinghe DK
- Abidi SH
- AbouZeid OS
- Abraham NL
- Abramowicz H
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- Publication venue
- Publication date
- 01/01/2022
- Field of study
The design and performance of the inner detector trigger for the high level trigger of the ATLAS experiment at the Large Hadron Collider during the 2016-2018 data taking period is discussed. In 2016, 2017, and 2018 the ATLAS detector recorded 35.6 fb(-1), 46.9 fb(-1), and 60.6 fb(-1) respectively of proton-proton collision data at a centre-of-mass energy of 13TeV. In order to deal with the very high interaction multiplicities per bunch crossing expected with the 13TeV collisions the inner detector trigger was redesigned during the long shutdown of the Large Hadron Collider from 2013 until 2015. An overview of these developments is provided and the performance of the tracking in the trigger for the muon, electron, tau and b-jet signatures is discussed. The high performance of the inner detector trigger with these extreme interaction multiplicities demonstrates how the inner detector tracking continues to lie at the heart of the trigger performance and is essential in enabling the ATLAS physics programme
Pan-cancer analysis of whole genomes
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- The ICGC/TCGA Pan-Cancer Analysis of Whole Genomes Consortium View Correspondence (jump link)
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- Zhang H. b
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- Zheng
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- zt Kim
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- Ă. A. th
- Ă. sk
- Publication venue
- Publication date
- 11/12/2019
- Field of study
Cancer is driven by genetic change, and the advent of massively parallel sequencing has enabled systematic documentation of this variation at the whole-genome scale(1-3). Here we report the integrative analysis of 2,658 whole-cancer genomes and their matching normal tissues across 38 tumour types from the Pan-Cancer Analysis of Whole Genomes (PCAWG) Consortium of the International Cancer Genome Consortium (ICGC) and The Cancer Genome Atlas (TCGA). We describe the generation of the PCAWG resource, facilitated by international data sharing using compute clouds. On average, cancer genomes contained 4-5 driver mutations when combining coding and non-coding genomic elements; however, in around 5% of cases no drivers were identified, suggesting that cancer driver discovery is not yet complete. Chromothripsis, in which many clustered structural variants arise in a single catastrophic event, is frequently an early event in tumour evolution; in acral melanoma, for example, these events precede most somatic point mutations and affect several cancer-associated genes simultaneously. Cancers with abnormal telomere maintenance often originate from tissues with low replicative activity and show several mechanisms of preventing telomere attrition to critical levels. Common and rare germline variants affect patterns of somatic mutation, including point mutations, structural variants and somatic retrotransposition. A collection of papers from the PCAWG Consortium describes non-coding mutations that drive cancer beyond those in the TERT promoter(4); identifies new signatures of mutational processes that cause base substitutions, small insertions and deletions and structural variation(5,6); analyses timings and patterns of tumour evolution(7); describes the diverse transcriptional consequences of somatic mutation on splicing, expression levels, fusion genes and promoter activity(8,9); and evaluates a range of more-specialized features of cancer genomes(8,10-18).Peer reviewe
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1.
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- Abdelfatah S
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- Zhu H
- Zhu H
- Zhu W-G
- Zhu Y
- Zhu Y
- Zhuang H
- Zhuang X
- Zientara-Rytter K
- Zimmermann CM
- Ziviani E
- Zoladek T
- Zong W-X
- Zorov DB
- Zorzano A
- Zou W
- Zou Z
- Zou Z
- Zuryn S
- Zwerschke W
- Ălvarez ĂMC
- Ăvalos Y
- Ănal G
- ĂstĂŒn S
- ÄoliÄ M
- ÄokiÄ J
- Ćœerovnik E
- Publication venue
- 'Informa UK Limited'
- Publication date
- 01/01/2021
- Field of study
In 2008, we published the first set of guidelines for standardizing research in autophagy. Since then, this topic has received increasing attention, and many scientists have entered the field. Our knowledge base and relevant new technologies have also been expanding. Thus, it is important to formulate on a regular basis updated guidelines for monitoring autophagy in different organisms. Despite numerous reviews, there continues to be confusion regarding acceptable methods to evaluate autophagy, especially in multicellular eukaryotes. Here, we present a set of guidelines for investigators to select and interpret methods to examine autophagy and related processes, and for reviewers to provide realistic and reasonable critiques of reports that are focused on these processes. These guidelines are not meant to be a dogmatic set of rules, because the appropriateness of any assay largely depends on the question being asked and the system being used. Moreover, no individual assay is perfect for every situation, calling for the use of multiple techniques to properly monitor autophagy in each experimental setting. Finally, several core components of the autophagy machinery have been implicated in distinct autophagic processes (canonical and noncanonical autophagy), implying that genetic approaches to block autophagy should rely on targeting two or more autophagy-related genes that ideally participate in distinct steps of the pathway. Along similar lines, because multiple proteins involved in autophagy also regulate other cellular pathways including apoptosis, not all of them can be used as a specific marker for bona fide autophagic responses. Here, we critically discuss current methods of assessing autophagy and the information they can, or cannot, provide. Our ultimate goal is to encourage intellectual and technical innovation in the field