Hydrodynamics of liquids of arbitrarily curved flux-lines and vortex loops

We derive a hydrodynamic model for a liquid of arbitrarily curved flux-lines and vortex loops using the mapping of the vortex liquid onto a liquid of relativistic charged quantum bosons in 2+1 dimensions recently suggested by Tesanovic and by Sudbo and collaborators. The loops in the flux-line system correspond to particle-antiparticle fluctuations in the bosons. We explicitly incorporate the externally applied magnetic field which in the boson model corresponds to a chemical potential associated with the conserved charge density of the bosons. We propose this model as a convenient and physically appealing starting point for studying the properties of the vortex liquid

Toadfish

24 p. : ill. ; 24 cm.Includes bibliographical references (p. 21-24)."Opsanus phobetron is described from the western Bahamas, Cuba, and the Isle of Pines. It was observed to nest in late December at Bimini, Bahamas. The black mouth functions as a warning mechanism, and under low albedo conditions, as at Bimini, the dark coloration is indicated to be of social significance. Attention is called to unidentified samples of Opsanus from Little Bahama Bank and the Gulf of Campeche. The ranges and recognition characters of O. pardus, O. tau, O. beta, and O. barbatus are discussed. Opsanus vandeuseni Fowler is referred to the synonymy of Opsanus beta (Goode and Bean). Opsanus hildebrandi Breder is placed in Marcgravia Jordan and appears not to be identical with M. ctyptocentra (Cuvier and Valenciennes). The low numbers of dorsal and anal rays attributed to Opsanus in the literature are valid if the Queensland genus Batrachoemus Ogilby is considered identical with Opsanus. Published paleotemperature measurements indicate that the 'tropical' Atlantic and Caribbean regions were not tropical during the last glacial period. The trans-Florida faunal province, now absent from southern Florida, was continuous around the southern tip of the Florida land mass; at the same time coral reefs were absent from most of the West Indies, and the shore fauna was predominantly temperate in the north and predominantly subtropical in the south. It is improbable that the Florida peninsula neck was submerged during Pleistocene interglacial periods. The presence of marine fishes in Florida fresh waters is not considered significant from the standpoint of historical zoogeography, and it is suggested that the elevated chlorinities in Florida fresh waters are maintained by current processes. Even if the neck of the Florida peninsula had been drowned, the Gulf of Mexico populations of trans-Florida fishes probably could not utilize the passage, as the temperatures would have been too high. The Gulf of Mexico disjunct trans-Florida populations are interpreted as glacial rather than interglacial relicts, and a comparison is drawn between the Gulf of Mexico and the Sea of Okhotsk. Because the spawning threshold temperature of Opsanus parallels the minimal thermal tolerance of reef corals, Opsanus is considered to be an 'indicator' of temperate coastal waters. Owing to thermal requirements and tolerances, Opsanus survives as a glacial relict in a few West Indian localities. During the last glacial period, the northern distributional limit for Opsanus may have been as far south as southern Florida. Opsanus, lacking pelagic life-history stages, could have dispersed through the West Indies by passive transport during storms"--P. 20-21

Regulation of valve endothelial cell vasculogenic network architectures with ROCK and Rac inhibitors

Objective: The age- and disease-dependent presence of microvessels within heart valves is an understudied characteristic of these tissues. Neovascularization involves endothelial cell (EC) migration and cytoskeletal reorientation, which are heavily regulated by the Rho family of GTPases. Given that valve ECs demonstrate unique mesenchymal transdifferentiation and cytoskeletal mechanoresponsiveness, compared to vascular ECs, this study quantified the effect of inhibiting two members of the Rho family on vasculogenic network formation by valve ECs. Approach and results: A tubule-like structure vasculogenesis assay (assessing lacunarity, junction density, and vessel density) was performed with porcine aortic valve ECs treated with small molecule inhibitors of Rho-associated serine-threonine protein kinase (ROCK), Y-27632, or the Rac1 inhibitor, NSC-23766. Actin coordination, cell number, and cell migration were assessed through immunocytochemistry, MTT assay, and scratch wound healing assay. ROCK inhibition reduced network lacunarity and interrupted proper cell–cell adhesion and actin coordination. Rac1 inhibition increased lacunarity and delayed actin-mediated network formation. ROCK inhibition alone significantly inhibited migration, whereas both ROCK and Rac1 inhibition significantly reduced cell number over time compared to controls. Compared to a vascular EC line, the valve ECs generated a network with larger total vessel length, but a less smooth appearance. Conclusions: Both ROCK and Rac1 inhibition interfered with key processes in vascular network formation by valve ECs. This is the first report of manipulation of valve EC vasculogenic organization in response to small molecule inhibitors. Further study is warranted to comprehend this facet of valvular cell biology and pathology and how it differs from vascular biology

Effect of increased rearing temperature on digestive function in cobia early juvenile

The present study is focused to elucidate the main characteristics of the digestive function of this carnivorous fast-growing fish living at high temperatures. With this aim, we have examined the effects of an increased temperature from 30 to 34 °C on the daily pattern of gastrointestinal pH, enzymatic proteolytic digestive activity and the feed transit time in early juveniles of cobia (Rachycentron canadum), a species living in tropical and subtropical waters with an increasing aquaculture production. Fish were fed two meals a day. Gastric luminal pH was permanently acidic (mean pH values: 2.76-4.74) while the intestinal pH increased from neutral/slightly acidic to slightly alkaline when the digesta was present, with an increasing alkalinity from proximal to distal intestine (mean pH values: 6.05 to 7.69). The temperature did not affect the gastric pH but a slightly higher acidity was induced in the intestine at 34 °C. Pepsin activity showed a daily rhythm at 30 °C with maximum in the middle of the light period, while at 34 °C some hourly changes coinciding with feed adding without a clear daily trend during the 24-h period were observed. The trypsin activity exhibited a daily rhythm at both temperatures with an increase after morning feeding to reach a maximum several hours later. Average pepsin activity during the daily cycle was slightly higher at 34 °C (6.1 and 7.3 U mg-1 BW at 30 and 34 °C respectively), but values were significantly different only at 8 and 24 h after the morning meal. Similarly, the trypsin activity was significantly affected by the temperature only at 8 and 16 h after the morning meal, but daily activity averages were similar (1.20 and 1.29 U g-1 BW at 30 and 34 °C respectively). The partial transit rates of the first meal in the stomach for each period inter-samplings were higher during the first 4-h period and decreased progressively along the rest of the 24-h cycle at both temperatures, but no significant differences were detected at 30 °C. In addition, the transit was notably faster at 34 °C particularly during the first 8 h after feeding, with rates between 100 and 65% of total volume displaced (intake or released) during each 4-h period. In the intestine the transit rate was relatively constant and similar at both temperatures during 12 h after feeding. Then the rates remained very low during the following 12 h. Residence time of the first meal was longer at 30 than at 34 °C, particularly in the stomach (12 h:02 min vs 4 h:54 min respectively). In the intestine the difference was not so large (8 h:18 min vs 6 h:24 min respectively). In a parallel study under same conditions, cobia reared at 30 °C grew faster and showed a more favorable feed conversion ratio than those at elevated temperature (34 °C). The present results indicate that at 34 °C, a subtle increase of proteolytic activity cannot compensate for the faster gut transit rate. Therefore, 30 °C is more appropriate temperature for the early on-growing of cobia because at higher temperatures the digestion efficiency decrease being one of the causes for a lower growth.Agência financiadora European Union (EU) 691150 MINECO, Spain + FEDER/ERDF contribution EFISHDIGESTAGL2014-52888 European Social Fund, the Operational Programme Human Potential IF/00482/2014/CP1217/CT0005 Portuguese Foundation for Science and Technology Portuguese Foundation for Science and Technology UDI/Multi/04326/2013 Norwegian Agency for Development Cooperation NORHED QZA-0485 SRV-13/0010info:eu-repo/semantics/publishedVersio

Superconducting Coherence and the Helicity Modulus in Vortex Line Models

We show how commonly used models for vortex lines in three dimensional superconductors can be modified to include k=0 excitations. We construct a formula for the k=0 helicity modulus in terms of fluctuations in the projected area of vortex loops. This gives a convenient criterion for the presence of superconducting coherence. We also present Monte Carlo simulations of a continuum vortex line model for the melting of the Abrikosov vortex lattice in pure YBCO.Comment: 4 pages RevTeX, 2 eps figures included using eps

Vortex-line liquid phases: Longitudinal superconductivity in the lattice London model

We study the vortex-line lattice and liquid phases of a clean type-II superconductor by means of Monte Carlo simulations of the lattice London model. Motivated by a recent controversy regarding the presence, within this model, of a vortex-liquid regime with longitudinal superconducting coherence over long length scales, we directly compare two different ways to calculate the longitudinal coherence. For an isotropic superconductor, we interpret our results in terms of a temperature regime within the liquid phase in which longitudinal superconducting coherence extends over length scales larger than the system thickness studied. We note that this regime disappears in the moderately anisotropic case due to a proliferation, close to the flux-line lattice melting temperature, of vortex loops between the layers.Comment: 8 pages, Revtex, with eps figures. To appear in Phys. Rev.

BDNF overexpression in mouse hippocampal astrocytes promotes local neurogenesis and elicits anxiolytic-like activities.

The therapeutic activity of selective serotonin (5-HT) reuptake inhibitors (SSRIs) relies on long-term adaptation at pre- and post-synaptic levels. The sustained administration of SSRIs increases the serotonergic neurotransmission in response to a functional desensitization of the inhibitory 5-HT1A autoreceptor in the dorsal raphe. At nerve terminal such as the hippocampus, the enhancement of 5-HT availability increases brain-derived neurotrophic factor (BDNF) synthesis and signaling, a major event in the stimulation of adult neurogenesis. In physiological conditions, BDNF would be expressed at functionally relevant levels in neurons. However, the recent observation that SSRIs upregulate BDNF mRNA in primary cultures of astrocytes strongly suggest that the therapeutic activity of antidepressant drugs might result from an increase in BDNF synthesis in this cell type. In this study, by overexpressing BDNF in astrocytes, we balanced the ratio between astrocytic and neuronal BDNF raising the possibility that such manipulation could positively reverberate on anxiolytic-/antidepressant-like activities in transfected mice. Our results indicate that BDNF overexpression in hippocampal astrocytes produced anxiolytic-/antidepressant-like activity in the novelty suppressed feeding in relation with the stimulation of hippocampal neurogenesis whereas it did not potentiate the effects of the SSRI fluoxetine on these parameters. Moreover, overexpressing BDNF revealed the anxiolytic-like activity of fluoxetine in the elevated plus maze while attenuating 5-HT neurotransmission in response to a blunted downregulation of the 5-HT1A autoreceptor. These results emphasize an original role of hippocampal astrocytes in the synthesis of BDNF, which can act through neurogenesis-dependent and -independent mechanisms to regulate different facets of anxiolytic-like responses

The Alexander-Orbach conjecture holds in high dimensions

We examine the incipient infinite cluster (IIC) of critical percolation in regimes where mean-field behavior has been established, namely when the dimension d is large enough or when d>6 and the lattice is sufficiently spread out. We find that random walk on the IIC exhibits anomalous diffusion with the spectral dimension d_s=4/3, that is, p_t(x,x)= t^{-2/3+o(1)}. This establishes a conjecture of Alexander and Orbach. En route we calculate the one-arm exponent with respect to the intrinsic distance.Comment: 25 pages, 2 figures. To appear in Inventiones Mathematica

Fractal superconductivity near localization threshold

We develop a semi-quantitative theory of electron pairing and resulting superconductivity in bulk "poor conductors" in which Fermi energy $E_F$ is located in the region of localized states not so far from the Anderson mobility edge $E_c$. We review the existing theories and experimental data and argue that a large class of disordered films is described by this model. Our theoretical analysis is based on the analytical treatment of pairing correlations, described in the basis of the exact single-particle eigenstates of the 3D Anderson model, which we combine with numerical data on eigenfunction correlations. Fractal nature of critical wavefunction's correlations is shown to be crucial for the physics of these systems. We identify three distinct phases: 'critical' superconductive state formed at $E_F=E_c$, superconducting state with a strong pseudogap, realized due to pairing of weakly localized electrons and insulating state realized at $E_F$ still deeper inside localized band. The 'critical' superconducting phase is characterized by the enhancement of the transition temperature with respect to BCS result, by the inhomogeneous spatial distribution of superconductive order parameter and local density of states. The major new feature of the pseudo-gaped state is the presence of two independent energy scales: superconducting gap $\Delta$, that is due to many-body correlations and a new "pseudogap" energy scale $\Delta_P$ which characterizes typical binding energy of localized electron pairs and leads to the insulating behavior of the resistivity as a function of temperature above superconductive $T_c$. Two gap nature of the "pseudo-gaped superconductor" is shown to lead to a number of unusual physical properties.Comment: 110 pages, 39 figures. The revised version corrects a number of typos, adds references and discussion of recent result

Stress corrosion cracking in Al-Zn-Mg-Cu aluminum alloys in saline environments

Copyright 2013 ASM International. This paper was published in Metallurgical and Materials Transactions A, 44A(3), 1230 - 1253, and is made available as an electronic reprint with the permission of ASM International. One print or electronic copy may be made for personal use only. Systematic or multiple reproduction, distribution to multiple locations via electronic or other means, duplications of any material in this paper for a fee or for commercial purposes, or modification of the content of this paper are prohibited.Stress corrosion cracking of Al-Zn-Mg-Cu (AA7xxx) aluminum alloys exposed to saline environments at temperatures ranging from 293 K to 353 K (20 °C to 80 °C) has been reviewed with particular attention to the influences of alloy composition and temper, and bulk and local environmental conditions. Stress corrosion crack (SCC) growth rates at room temperature for peak- and over-aged tempers in saline environments are minimized for Al-Zn-Mg-Cu alloys containing less than ~8 wt pct Zn when Zn/Mg ratios are ranging from 2 to 3, excess magnesium levels are less than 1 wt pct, and copper content is either less than ~0.2 wt pct or ranging from 1.3 to 2 wt pct. A minimum chloride ion concentration of ~0.01 M is required for crack growth rates to exceed those in distilled water, which insures that the local solution pH in crack-tip regions can be maintained at less than 4. Crack growth rates in saline solution without other additions gradually increase with bulk chloride ion concentrations up to around 0.6 M NaCl, whereas in solutions with sufficiently low dichromate (or chromate), inhibitor additions are insensitive to the bulk chloride concentration and are typically at least double those observed without the additions. DCB specimens, fatigue pre-cracked in air before immersion in a saline environment, show an initial period with no detectible crack growth, followed by crack growth at the distilled water rate, and then transition to a higher crack growth rate typical of region 2 crack growth in the saline environment. Time spent in each stage depends on the type of pre-crack (“pop-in” vs fatigue), applied stress intensity factor, alloy chemistry, bulk environment, and, if applied, the external polarization. Apparent activation energies (E a) for SCC growth in Al-Zn-Mg-Cu alloys exposed to 0.6 M NaCl over the temperatures ranging from 293 K to 353 K (20 °C to 80 °C) for under-, peak-, and over-aged low-copper-containing alloys (~0.8 wt pct), they are typically ranging from 20 to 40 kJ/mol for under- and peak-aged alloys, and based on limited data, around 85 kJ/mol for over-aged tempers. This means that crack propagation in saline environments is most likely to occur by a hydrogen-related process for low-copper-containing Al-Zn-Mg-Cu alloys in under-, peak- and over-aged tempers, and for high-copper alloys in under- and peak-aged tempers. For over-aged high-copper-containing alloys, cracking is most probably under anodic dissolution control. Future stress corrosion studies should focus on understanding the factors that control crack initiation, and insuring that the next generation of higher performance Al-Zn-Mg-Cu alloys has similar longer crack initiation times and crack propagation rates to those of the incumbent alloys in an over-aged condition where crack rates are less than 1 mm/month at a high stress intensity factor