Educating for Information Literacy : Assessing Indian Agricultural Sciences graduate’s knowledge and Information skills

The article makes as survey of graduate students knowledge on use of various library and learning resources and their information skills. Students across disciplines of Horticulture, Seed science, Vegetable science of G B Pant University of Agriculture & Technology were assessed, questions were posed to know how they perceived themselves capable of knowing information sources, arrangement, interpretation and location of physical items in library, knowledge of bibliographical database, academic search engines, use of library website, subject gateways, and library networks etc. The survey also makes an effort to know students attitude as to how they informed themselves about latest development in their subject and how they would like to be informed about library news and learning resources. The survey was made before the commencement of one credit course on information literacy, and the limited knowledge of graduate students was expected in skill areas. The finding reveals that there are notable gaps and students’ knowledge is digitally divided. Suggests that teaching of credit bearing IL courses is imperative to enhance graduate students knowledge and information seeking skills

Educating for Information Literacy : Assessing Indian Agricultural Sciences graduate’s knowledge and Information skills

The article makes as survey of graduate students knowledge on use of various library and learning resources and their information skills. Students across disciplines of Horticulture, Seed science, Vegetable science of G B Pant University of Agriculture & Technology were assessed, questions were posed to know how they perceived themselves capable of knowing information sources, arrangement, interpretation and location of physical items in library, knowledge of bibliographical database, academic search engines, use of library website, subject gateways, and library networks etc. The survey also makes an effort to know students attitude as to how they informed themselves about latest development in their subject and how they would like to be informed about library news and learning resources. The survey was made before the commencement of one credit course on information literacy, and the limited knowledge of graduate students was expected in skill areas. The finding reveals that there are notable gaps and students’ knowledge is digitally divided. Suggests that teaching of credit bearing IL courses is imperative to enhance graduate students knowledge and information seeking skills

Advances in the Rehabilitation of Hemispatial Inattention

PURPOSE OF REVIEW: There continue to be a plethora of approaches to the rehabilitation of hemispatial inattention, from different forms of sensory stimulation (visual, auditory and somatosensory feedback), through all major modes of non-invasive brain stimulation to drug therapies. Here we summarise trials published in the years 2017-2022 and tabulate their effect sizes, with the aim of drawing on common themes that may serve to inform future rehabilitative studies. RECENT FINDINGS: Immersive virtual reality approaches to visual stimulation seem well tolerated, although they have yet to yield any clinically relevant improvements. Dynamic auditory stimulation looks very promising and has high potential for implementation. Robotic interventions are limited by their cost and are perhaps best suited to patients with a co-occurring hemiparesis. Regarding brain stimulation, rTMS continues to demonstrate moderate effects but tDCS studies have yielded disappointing results so far. Drugs, primarily aimed at the dopaminergic system, often demonstrate beneficial effects of a medium size, but as with many of the approaches, it seems difficult to predict responders and non-responders. Our main recommendation is that researchers consider incorporating single-case experimental designs into their studies as rehabilitation trials are likely to remain small in terms of patient numbers, and this is the best way to deal with all the factors that cause large between-subject heterogeneity

Case study: sarcoidosis

No Abstrac

FORMULATION AND CHARACTERIZATION OF HPMC AND HPMCAS BASED SOLID DISPERSIONS OF FENOFIBRATE: A COMPARATIVE STUDY

Objective: The aim of the present study was to investigate the effect of novel polymeric carriers and to develop solid dispersion formulation that could improve in vitro profile of Fenofibrate (FB). Methods: Spray drying technique was used to fabricate solid dispersions with hydrophilic carriers, mainly hydroxypropyl methylcellulose (HPMC) and hydroxypropyl methylcellulose acetate succinate (HPMCAS). Solid dispersions in the form of spray-dried powder were characterized with respect to the pure drug and the corresponding physical mixtures by optical microscopy, x-ray diffraction (XRD), fourier transform infrared (FT-IR) spectroscopy and differential scanning calorimetry (DSC). Size and morphology of optimized solid dispersion were performed by scanning electron microscopy (SEM). Furthermore, in vitro dissolution comparisons were carried out between the optimized solid dispersion against the pure drug and the physical mixtures. Results: Solubility studies demonstrated that the solubility of FB was not affected by pH change. The transformation of crystalline FB into an amorphous solid dispersion powder has been clearly demonstrated by optical microscopy. The molecular dispersion of drug in the dispersion matrix prepared by spray drying was confirmed in XRD and DSC studies. IR spectroscopy was observed with negligible incompatibility of the drug with polymers. Spherical morphology was observed in SEM with no evidence of FB crystals. The prepared solid dispersions exhibited dissolution improvement as compared to the pure drug and spray dried FB in 0.05 M SLS, with HPMCAS as the superior carrier over HPMC. Conclusion: The present study vouches better in vitro profile of FB from spray-dried HPMCAS based solid dispersions

Iron content of ferritin modulates its uptake by intestinal epithelium: implications for co-transport of prions

The spread of Chronic Wasting Disease (CWD) in the deer and elk population has caused serious public health concerns due to its potential to infect farm animals and humans. Like other prion disorders such a sporadic Creutzfeldt-Jakob-disease of humans and Mad Cow Disease of cattle, CWD is caused by PrP-scrapie (PrPSc), a β-sheet rich isoform of a normal cell surface glycoprotein, the prion protein (PrPC). Since PrPSc is sufficient to cause infection and neurotoxicity if ingested by a susceptible host, it is important to understand the mechanism by which it crosses the stringent epithelial cell barrier of the small intestine. Possible mechanisms include co-transport with ferritin in ingested food and uptake by dendritic cells. Since ferritin is ubiquitously expressed and shares considerable homology among species, co-transport of PrPSc with ferritin can result in cross-species spread with deleterious consequences. We have used a combination of in vitro and in vivo models of intestinal epithelial cell barrier to understand the role of ferritin in mediating PrPSc uptake and transport. In this report, we demonstrate that PrPSc and ferritin from CWD affected deer and elk brains and scrapie from sheep resist degradation by digestive enzymes, and are transcytosed across a tight monolayer of human epithelial cells with significant efficiency. Likewise, ferritin from hamster brains is taken up by mouse intestinal epithelial cells in vivo, indicating that uptake of ferritin is not limited by species differences as described for prions. More importantly, the iron content of ferritin determines its efficiency of uptake and transport by Caco-2 cells and mouse models, providing insight into the mechanism(s) of ferritin and PrPSc uptake by intestinal epithelial cells

To study second trimester placental location as a predictor of adverse pregnancy outcome

Background: Pregnancy and childbirth is universally celebrated as an event. It can also be one of experiences of misery and suffering when complications or adverse circumstances comprise the pregnancy, causing morbidity or even mortality. To study second trimester placental localization as a predictor of adverse pregnancy outcome.Methods: The study was conducted in Upper India Sugar Exchange Maternity Hospital, GSVM Medical College, Kanpur, India from January 2014 to July 2015 on 592 pregnant women between 18-24 week over a period of 16 months.Results: This study shows that lateral placental location was associated with increased incidence of preeclampsia, intrauterine growth restriction and posterior placental location associated with preterm labour and stillbirth.Conclusions: Placental localization by ultrasound in pregnant women during 18-24 week of gestation can be used as easy, non-invasive, cost-effective tool as a predictor of adverse pregnancy outcome

Monitoring of Blood Pressure using Invasive or Non-invasive Method in Critically Ill Patients: A Review

Blood pressure is a core vital sign used as a basis for diagnosis and management of patients in critical care setting. Blood pressure (BP) can be monitored by both invasive and non-invasive methods. Invasive blood measurement using arterial access is considered the “gold” standard in critically ill patients. However, invasive methods put patient at risk of bleeding and infection as compared to non-invasive methods. Non-invasive blood pressure monitoring can be obtained through oscillometric or manual auscultatory sphygmomanometer. The objective of this review is to provide a global perspective of health care providers towards use of invasive or non-invasive method of measuring blood pressure. Both theoretical and existing clinical studies have suggested that non-invasive measurements may differ from invasive intra-arterial estimates of blood pressure

CHANGING PERCEPTIONS OF RURAL YOUTH IN PUNJAB: A SOCIOLOGICAL STUDY IN AMRITSAR DISTRICT OF PUNJAB

ABSTRACT Transitional issues within a single generation vary not only according to time and place but also according t