Distal splenorenal shunt (DSRS) in children with extrahepatic portal hypertension

Portal hypertension (PH) is infrequent in children as compared to adults. Currently, repetitive endoscopic ablation of varices is standard treatment. However, endoscopic facilities are not readily available in resource-limited settings. We reviewed the indications, operative morbidity, mortality, shunt patency and re-bleeding episodes in nine patients (age range 6-16 years, M:F 6:3) who had DSRS for recurrent GI bleeding not responding to endoscopic treatment and hypersplenism. DSRS is a safe and effective treatment alternative in resource limiting setting for preventing bleeding and improving hypersplenism in children with extrahepatic portal hypertension

Titanium Cage Fixation in Thoracic and Thoraco-lumbar Anterior Inter-body Fusion

nner by inter body fusion. Study Design:  Prospective Study. Material and Method:  The study was conducted at the department of neurosurgery Lahore general hospital Lahore. Results:  Thirty cases were included during period two years. All cases operated for decompression, fusion and instrumentation, cages of titanium mesh were used. Neurological status of the patients assessed before and after operation. Twenty eight (93.3%) cases improved neurologically. Two (6.7%) did not improved. There were three infected cases which were treated and improved in the long run. Conclusion:  By using anterior interbody fusion (AIF) with cage we can mobilize the patient early. Improvement of the neurological status is excellent. Per operative infection rate is very low. Deformity can be corrected with more accuracy. Key Words:  Anterior cervical corpectomy, anterior dorsal inter body fusion, anterior, posterior and lateral, computed tommography, magnetic resonance imaging

RADIATION ASSISTED THERMONUCLEAR BURN WAVE DYNAMICS IN HEAVY ION FAST IGNITION OF CYLINDRICAL DT FUEL TARGET

Dynamics of thermonuclear burn wave propagation assisted by thermal radiation precursor in a heavy ion fast ignition of cy-lindrical deuterium-tritium (DT) fuel target are studied by two dimensional radiation hydrodynamic simulations using Multi-2D code. Thermal radiations, as they propagate ahead of the burn wave, suffer multiple reflections and preheat the fuel, are found to play a vital role in burn wave dynamics. After fuel ignition, the burn wave propagates in a steady state manner for some time. Multiple reflection and absorption of radiation at the fuel-tamper interface, fuel ablation and radial implosion driven by ablative shock and fast fusion rates on the fuel axis, at relatively later times, result into filamentary wave front. Strong pressure gradients are developed and sausage like structures behind the front are appeared. The situation leads to relatively reduced and non-uniform radial fuel burning and burn wave propagation. The fuel burning due to DD reaction is also taken into account and over-all fusion energy and fusion power density, due to DT and DD reactions, during the burn wave propagation are determined as a function of time

Formation Evaluation of Lower Goru Sands of Khipro Block, Lower Indus Basin, Pakistan

Formation evaluation is widely used in exploration and production in order to minimize the risk, uncertainty, and understanding of the detailed characteristics of potential reservoir rocks. This study is aimed to evaluate the Petrophysical characteristics of upper and lower basal sands of the Cretaceous lower Goru Formation in Niamat-01 and Siraj-01 wells and to focus on hydrocarbon exploration potential. These wells have been drilled in the Khipro block, lower Indus basin, which is the least explored for the reservoir quality evaluation. Present study characterized the lower Goru sands of the Khipro block. It is interpreted that the thickness of upper and lower Basal sands are 13m and 10m, respectively in Naimat Basal 01, whereas 9m and 17m, respectively, are reported in SirajSouth-01. The average effective porosity is 11% in upper Basal sands while 26% is interpreted for lower Basal sand in Naimat Basal-01. An average porosity of 11% is found for upper Basal sands in Siraj South-01 and 11% for lower Basal sand. Water saturation (Sw) calculated for upper and lower Basal sands are 22% and 19%, respectively. The hydrocarbon saturation (Sh) of 78% is interpreted for upper Basal sands and 81% hydrocarbon saturation reported for lower Basal sands in Naimat basal-01. However, 36% and 45% Sw have been recognized for upper and lower Basal sands, respectively. Whereas hydrocarbon saturations of 64% and 55% are reported for the upper and lower basal sands, respectively, in SirajSouth-01. Crossover effects in front of targeted formations confirmed the presence of hydrocarbons in the zone of interest. Lower sands of the lower Goru Formation in the Khipro block are favorable for hydrocarbon production and have potential for future hydrocarbon exploration activities

Increasing Trend of Silver Nanoparticles as Antibacterial and Anticancer Agent

Silver nanoparticles (AgNPs) synthesis from plants that already have been reported for medicinal purposes demonstrated better efficacy for curing diseases. Recently, a number of researches have been reported where AgNPs act as promising antibacterial and anticancer agent. Biosynthesized silver nanoparticles (AgNPs) are a type of environmentally friendly, cost-effective, and biocompatible substance that has gotten a lot of attention in treatment of cancer and inhibition of pathogenic microbes. In this chapter, a comprehensive report on the recent development of AgNPs as nanomedicine synthesized from plant extracts. The role and mechanism of AgNPs as antibacterial and anticancer agent was reported that leads towards development of targeted nannomedicines to treat infectious diseases and world most challenging disease like cancer. Reported literature give imminence importance of AgNPs and demonstrated more potency to treat cancer and bacterial infections

A Comparative Study of Cerium- and Ytterbium-Based GO/g-C3N4/Fe2O3 Composites for Electrochemical and Photocatalytic Applications

The design of sustainable and efficient materials for efficient energy storage and degradation of environmental pollutants (specifically organic dyes) is a matter of major interest these days. For this purpose, cerium- and ytterbium-based GO/g-C3N4/Fe2O3 composites have been synthesized to explore their properties, especially in charge storage devices such as supercapacitors, and also as photocatalysts for the degradation of carcinogenic dyes from the environment. Physicochemical studies have been carried out using XRD, FTIR, SEM, and BET techniques. Electrochemical techniques (cyclic voltammetry, galvanic charge discharge, and electrochemical impedance spectroscopy) have been employed to measure super-capacitance and EDLC properties. Results show that the gravimetric capacitance calculated from GCD results is 219 Fg−1 for ytterbium- and 169 Fg−1 for cerium-based nanocomposites at the current density of 1 A/g and scan rate of 2 mV/sec. The specific capacitance calculated for the ytterbium-based nanocomposite is 189 Fg−1 as compared to 125 Fg−1 for the cerium-based material. EIS results pointed to an enhanced resistance offered by cerium-based nanocomposites as compared to that of ytterbium, which can be assumed with the difference in particle size, as confirmed from structural studies including XRD. From obtained results, ytterbium oxide-based GO/g-C3N4/Fe2O3 is proven to be a better electro-catalyst as compared to cerium-based nanocomposites. Photocatalytic results are also in agreement with electrochemical results, as the degradation efficiency of ytterbium oxide-based GO/g-C3N4/Fe2O3 (67.11 and 83.50% for rhodamine B and methylene blue dyes) surpasses values observed for cerium-based GO/g-C3N4/Fe2O3 (63.08 and 70.61%)

An Assessment of the Causes of Drop outs in Primary Schools of Mountainous Areas of District Swat

The study was conducted in the mountainous areas of district Swat in the year 2010 to assess the causes of drop outs in primary schools of mountainous areas. Primary data was obtained through three different structured questionnaires using a sample of size sixty allocating to fifty government schools of three districts of the research area. The schools and respondents in the hilly area were randomly selected. The findings of the study showed that the major causes of drop outs in the research area were crowded and large schools; uncaring, untrained and irresponsible teachers; usage of passive teaching methods; inappropriate curriculum design; inappropriate evaluation procedure; lack of parents’ involvement; lack of checks and bureaucratic system and long distance and lack of extra co curricular activities. It is recommended that the government authorities should have strict checks on these schools. The presence of the staff, usage of audio visual aids in teaching process and students’ involvement in co-curriculum activities should be ensured

An Assessment of the Causes of Drop outs in Primary Schools of Mountainous Areas of District Swat

The study was conducted in the mountainous areas of district Swat in the year 2010 to assess the causes of drop outs in primary schools of mountainous areas. Primary data was obtained through three different structured questionnaires using a sample of size sixty allocating to fifty government schools of three districts of the research area. The schools and respondents in the hilly area were randomly selected. The findings of the study showed that the major causes of drop outs in the research area were crowded and large schools; uncaring, untrained and irresponsible teachers; usage of passive teaching methods; inappropriate curriculum design; inappropriate evaluation procedure; lack of parents’ involvement; lack of checks and bureaucratic system and long distance and lack of extra co curricular activities. It is recommended that the government authorities should have strict checks on these schools. The presence of the staff, usage of audio visual aids in teaching process and students’ involvement in co-curriculum activities should be ensured

3,4-Dimethyl­pyrano[2,3-c]pyrazol-6(2H)-one

The asymmetric unit of the title compound, C8H8N2O2, comprises two independent mol­ecules in both of which, all non-H atoms lie in a common plane (r.m.s. deviation = 0.014 and 0.017 Å). In the crystal, N—H⋯O hydrogen bonds connect the mol­ecules into zigzag chains running along [10-1]. Weak C—H⋯O inter­actions connect the chains into an infinite network