Mammographic density adds accuracy to both the Tyrer-Cuzick and Gail breast cancer risk models in a prospective UK screening cohort

This work was supported by the National Institute for Health Research (NIHR) and Genesis Breast Cancer Prevention Appeal (references GA10-033 and GA13-006). This article presents independent research funded by the NIHR under its Programme Grants for Applied Research (grant RP-PG-0707-10031). The views expressed are those of the authors and not necessarily those of the NHS, the NIHR or the Department of Health. The authors also acknowledge the support of Medical Research Council Health eResearch Centre grant MR/K006665/1

The psychosocial impact of ductal carcinoma in situ (DCIS): a longitudinal prospective study.

DCIS is a non-invasive breast cancer, increasingly detected through routine breast screening. Patients are reassured that the condition is early and not life-threatening but they undergo surgery similar to that used in the treatment of invasive breast cancer (IBC). Little research has explored the psychosocial impact of DCIS, especially in the UK. A longitudinal, prospective study was therefore conducted to address this gap. Fifty women newly diagnosed with DCIS were followed over the first year post-diagnosis. Anxiety and depression significantly reduced from baseline to 6 months. Body image distress was relatively stable, but extensive for some women. Those undergoing mastectomy with immediate reconstruction experienced significantly greater body image concerns. This study highlights that DCIS patients can experience psychosocial distress that is often transient but in some cases extensive and prolonged. Appropriate psychosocial support is needed to help DCIS patients adjust to the diagnosis, its treatment and long-term implications