12 research outputs found
Prelude to Passion: Limbic Activation by “Unseen” Drug and Sexual Cues
- Author
- A Ohman
- AG Greenwald
- Aldo Rustichini
- AM Dale
- Anna Rose Childress
- AR Childress
- AR Childress
- BJ Everitt
- C Darwin
- Charles P. O'Brien
- D Greve
- D Holender
- Daniel Langleben
- Freud
- H Garavan
- H Garavan
- IP Pavlov
- Jesse Suh
- John Detre
- John Listerud
- Jonathan Hakun
- JS Morris
- JS Morris
- Kathleen Marquez
- M Overgaard
- M Pessiglione
- Nathan Sciortino
- P Wright
- PJ Lang
- PJ Whalen
- PJ Whalen
- PM Merikle
- RB Adams Jr
- RH Fazio
- RN Ehrman
- Ronald N. Ehrman
- S Hamann
- S Karama
- SB Hamann
- SL Rauch
- SM McClure
- ST Murphy
- T Hendler
- Teresa Franklin
- WD Killgore
- WD Killgore
- William Jens
- YI Sheline
- Yin Li
- Ze Wang
- Publication venue
- Public Library of Science
- Publication date
- Field of study
Riociguat treatment in patients with chronic thromboembolic pulmonary hypertension: Final safety data from the EXPERT registry
- Author
- Abdelsayed A.A. (Abeer Abeer)
- Acosta A. (Adriana)
- Adams H. (Heath)
- Agostinho J. (João)
- Agostoni P. (Piergiuseppe)
- Airò E. (Edoardo)
- Al Dalaan A. (Abdullah)
- Alexandre M. (Myriam)
- Alexeeva D.E. (Dalyana Eduardovna)
- Alfetlawi M. (Monthir)
- Almagro R.M. (Raúl Menor)
- Alonso L.P. (Lecue Pilar)
- Altraja A. (Alan)
- Andreassen A.K. (Arne K.)
- Anton L. (Ly)
- Argiento P. (Paola)
- Arjona J.J. (Josefa Jiménez)
- Asencio I. (Isabel)
- Atas H. (Halil)
- Avdeev S.N. (Sergey Nikolaevich)
- Avilés F.F. (Francisco Fernandez)
- Badagliacca R. (Roberto)
- Baptista R. (Rui)
- Barberá J.A. (Joan A.)
- Barry L. (Lisa)
- Bartfay S.-E. (Sven-Erik)
- Batalina M.V. (Marina Vadimovna)
- Bauleo C. (Carolina)
- Blanco I. (Isabel)
- Bohacekova M. (Marcela)
- Boogaard H. (H.)
- Boomars K.A.T. (Karin)
- Boonstra A. (Anco)
- Bosio M. (Martin)
- Bruno N. (Noemi)
- Bukatova I.F. (Irina Fedorovna)
- Camacho R.C. (Rafael Conde)
- Campo F. (Felipe)
- Caneva J. (Jorge)
- Capinha M. (Marta)
- Cardoso T. (Tania)
- Castro G. (Graça)
- Cheng C.-C. (Chin-Chang)
- Chu C.Y. (Chun Yuan)
- Church C. (Colin)
- Cifrián Martínez J.M. (José Manuel)
- Conte L. (Luca)
- Correra A. (Anna)
- Corris P. (Paul)
- Costa S. (Serena)
- Cottin V. (Vincent)
- Coutinho D. (Daniel)
- Cresci C. (Chiara)
- Cuesta V.M. (Victor Mora)
- Cárdenas S.L. (Salvador López)
- D'Alto M. (Michele)
- D'Armini A.M. (Andrea Maria)
- De La Pava S. (Sebastian)
- De Luca A. (Anna)
- De Pauw M. (Michel)
- Delcroix M. (Marion)
- Deleo S. (Sabino)
- Di Marco G.M. (Giovanni Maria)
- Diez M. (Mirta)
- Dwyer N. (Nathan)
- Egenlauf B. (Benjamin)
- Elias T. (Teresa)
- Escribano Subías P. (Pilar)
- Espinha M. (Mafalda)
- Evrard P. (Patrick)
- Ewert R. (Ralf)
- Fanaridis M. (Michail)
- Farina S. (Stefania)
- Farkasova I. (Iveta)
- Farruggio S. (Silvia)
- Feenstra J. (John)
- Feistmantl L.-T. (Lisa-Theresa)
- Fernandez D.I. (David Iturbe)
- Filippov E.V. (Evgeny Vladimirovich)
- Fong M.-C. (Man-Cai)
- Gaine S. (Sean)
- Galgano G. (Giuseppe)
- Gall H. (Henning)
- Galyavich A.S. (Albert Sarvatovich)
- Garcea A. (Alessio)
- Garcia A. (Alberto)
- Garcia P. (Paula)
- García S.A. (Salvador Alcaraz)
- Gasche-Soccal P. (Paola)
- Georgopoulos D. (Dimitrios)
- Gerhardt F. (Felix)
- Ghofrani H.A.
- Giannakoulas G. (George)
- Gomez Sanchez M.-A. (Miguel-Angel)
- Gomez J.E. (Juan Esteban)
- Grazioli V. (Valentina)
- Grimminger J. (Jan)
- Gruenberger M. (Margarethe)
- Grünig E. (Ekkehard)
- Guiot J. (Julien)
- Halank M. (Michael)
- Hanta I. (Ismail)
- Harbaum L. (Lars)
- Hegya D.V. (Daria Viktorovna)
- Helmersen D.S. (Douglas S.)
- Ho W.-J. (Wan-Jing)
- Hoeper M.M. (Marius M.)
- Hsu C.-H. (Chih-Hsin)
- Hsu P.-C. (Po-Chao)
- Hsu T.-S. (Tsu-Shiu)
- Huang C.-L. (Chien-Lung)
- Huang W.-C. (Wei-Chun)
- Huang W.-P. (Wen-Pin)
- Huber C. (Charlotte)
- Humbert M.
- Hung C.-S. (Chi-Sheng)
- Ivanov K.I. (Kyundyul Ivanovich)
- Jansa P. (Pavel)
- Jara L. (Luis)
- Karvounis H.I.
- Keogh A. (Anne)
- Klose H. (Hans)
- Klotsche J. (Jens)
- Knoop-Busch S. (Susanne)
- Kolomeytseva T.M. (Tatyana Mikhaylovna)
- Konstantinides S. (Stavros)
- Kotlyar E. (Eugene)
- Kotsia A. (Anna)
- Kramer T. (Tilmann)
- Kulka C. (Christine)
- Kuo P.-H. (Ping-Hung)
- Kuo S.-H. (Shu-Hung)
- Lador F. (Frédéric)
- Lai W.-T. (Wen-Ter)
- Lang I. (Irene)
- Lange T.J. (Tobias J.)
- Langleben D. (David)
- Lavender M. (Melanie)
- Lema C. (Camila)
- Lin J.-L. (Jiunn-Lee)
- Lin T.-H. (Tsung-Hsien)
- Lin Y.-H. (Yen-Hung)
- Lombardi F. (Francesco)
- Londoño A. (Alejandro)
- Lopez M. (Manuel)
- Lopez R. (Raquel)
- Louis R. (Renaud)
- Loureiro M.J. (Maria José)
- Lunardi C. (Claudio)
- Löffler-Ragg J. (Judith)
- Mackenzie M. (Michele)
- Mager J. (J.)
- Maldonado L. (Lorena)
- Manzi G. (Giovanna)
- Marinho A. (António)
- Marrero F.L. (Fernando León)
- Martinez W. (William)
- Martinez-Meñaca A. (Amaya)
- Martins Jesus S.M. (Susana Maria)
- Martynyuk T.V. (Tamila Vitalievna)
- Massola G. (Giulia)
- Mehta S. (Sanjay)
- Meier C. (Christian)
- Melatini L. (Luciano)
- Mellemkjaer S. (Soren)
- Michalis L.K. (Lampros)
- Mielniczuk L.M. (Lisa M.)
- Minson R. (Robert)
- Mitrouska I. (Ioanna)
- Mouratoglou S. (Sofia)
- Mulè M. (Massimiliano)
- Mutlu B. (Bülent)
- Naldi M. (Marco)
- Ndreu R. (Rudina)
- Newnham M. (Michael)
- Ng B. (Benjamin)
- Nielsen-Kudsk J.E. (Jens Erik)
- Nikolaevich B.A. (Bykov Aleksander)
- Nolde A. (Anna)
- Noël-Savina E. (Elise)
- Okumus G. (Gulfer)
- Oliveira A. (Ana)
- Olzik I. (Ilona)
- Ongen G. (Gul)
- Oqueka T. (Tim)
- Orozco-Levi M. (Mauricio)
- Otero R. (Remedios)
- Paciocco G. (Giuseppe)
- Pane F. (Federico)
- Pappas A. (Athanasios)
- Pappas K. (Konstantinos)
- Pavlickova I. (Ivana)
- Pavlova O.B. (Olga Borisovna)
- Peacock A. (Andrew)
- Pepke-Zaba J. (Joanna)
- Pesci A. (Alberto)
- Petruzzi M. (Mario)
- Peñate G.P. (Gregorio Pérez)
- Picariello C. (Claudio)
- Piccari L. (Lucilla)
- Pin M. (Maurizio)
- Pitsiou G. (Georgia)
- Pittrow D. (David)
- Platonov D.Y. (Dmitry Yurievich)
- Poscia R. (Roberto)
- Prediletto R. (Renato)
- Proudman S. (Susanna)
- Quezada C.A. (Carlos Andres)
- Reesink H.J. (Herre)
- Reeves G. (Glenn)
- Regotta S. (Sabine)
- Repolho D. (Débora)
- Rocha A. (Andreia)
- Rochat T. (Thierry)
- Rodríguez P.V. (Patricia Villanueva)
- Roman A. (Antonio)
- Roncon L. (Loris)
- Rosenkranz S. (Stephan)
- Rozas S.F. (Sonia Fernandez)
- Rundqvist B. (Bengt)
- Sadushi-Kolici R. (Roela)
- Sakkijha H. (Hussam)
- Saleemi S. (Sarferaz)
- Sardella L. (Luca)
- Schulz C. (Christian)
- Schwarz E.I. (Esther Irene)
- Sciortino A. (Antonio)
- Sebastian L. (Laura)
- Shearman N. (Nicole)
- Shiang T. (Teresa)
- Simon M. (Marcel)
- Simonneau G. (Gérald)
- Sitbon O. (Olivier)
- Skripkina E.S. (Elena Sergeevna)
- Snijder R.
- Sourla E. (Evdokia)
- Sousa J. (Joana)
- Speich R. (Rudolf)
- Stanopoulos I. (Ioannis)
- Steele P. (Peter)
- Steringer-Mascherbauer R. (Regina)
- Stevens W. (Wendy)
- Su H.-M. (Ho-Ming)
- Sung S.-H. (Shih-Hsien)
- Söderberg S. (Stefan)
- Talavera M.L. (Maria Lujan)
- Tania G. (Gonçalves)
- Tayler S. (Susanne)
- Tilea I. (Ioana)
- Toorn L.M. (Leon) van den
- Torricelli E. (Elena)
- Toshner M. (Mark)
- Tovar P.P. (Patricia Parada)
- Tregubova A.V. (Anna Viktorovna)
- Tsangaris I. (Iraklis)
- Tsareva N.A. (Natalia Anatolievna)
- Tuhay G. (Graciela)
- Têtu L. (Laurent)
- Ulrich S. (Silvia)
- Un Z. (Zeynep)
- Vachiéry J.-L. (Jean-Luc)
- Valkovicova T. (Tatiana)
- Vannucchi V. (Vieri)
- Vasankari T. (Tuija)
- Vihinen T. (Tapani)
- Vizza C.D. (Carmine Dario)
- Vonk Noordegraaf A. (Anton)
- Voon W.-C. (Wen-Chol)
- Vulcano N. (Norberto)
- Wang W.-H. (Wen-Hwa)
- Weheba I. (Ihab)
- Williams E. (Evgenia)
- Wirtz G. (Gil)
- Wirtz H. (Hubert)
- Wodlin P. (Peter)
- Wu C.-K. (Cho-Kai)
- Wu S.-H. (Shu-Hao)
- Yakovleva O.E. (Olga Eduardovna)
- Yen H.-W. (Hsueh-Wei)
- Yih-Jer Wu J. (Jacob)
- Yotti R. (Raquel)
- Zvereva T.N. (Tatyana Nikolaevna)
- Šimková I. (Iveta)
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/03/2021
- Field of study
Objective: The soluble guanylate cyclase stimulator riociguat is approved for the treatment of adult patients with pulmonary arterial hypertension (PAH) and inoperable or persistent/recurrent chronic thromboembolic pulmonary hypertension (CTEPH) following Phase
Menstrual Cycle Phase at Quit Date Predicts Smoking Status in an NRT Treatment Trial: A Retrospective Analysis
- Author
- Publication venue
- 'Mary Ann Liebert Inc'
- Publication date
- Field of study
Modulation of resting brain cerebral blood flow by the GABA B agonist, baclofen: A longitudinal perfusion fMRI study
- Author
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/01/2011
- Field of study
Modulation of resting brain cerebral blood flow by the GABA B agonist, baclofen: a longitudinal perfusion fMRI study
- Author
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/09/2011
- Field of study
Changing the State of State-Level Energy Programs: Policy Diffusion, Economic Stimulus, and New Federalism Paradigms
- Author
- American Recovery and Reinvestment Act Board
- Beyle T.L.
- Biden JR
- Brandeis L.D.
- British Broadcasting Corporation (BBC)
- Brooks G.E.
- Brown M.
- Brown M.
- Buchanan J.M.
- Database of State Incentives for Efficiency and Renewables (DSIRE)
- Deitchman B.
- Derthick M.
- Energy Information Administration (EIA)
- Galbraith K.
- Grunwald M.
- Harrigan J.J.
- Herzik E.B.
- Hollis D.B.
- Madison J.
- Nathan R.P.
- National Association of Energy Service Companies (NAESCO)
- National Governors Association
- National Governors Association
- New York State Energy Research and Development Authority (NYSERDA)
- Pollin R.
- Polsby N.W.
- Posner P.
- Rabe B.
- Ransone C.B.
- Revesz R.
- Revesz R.
- Rose C.
- Rosencranz A.
- Schlesinger J.A.
- Sciortino M.
- Selin H.
- Stavins R.N.
- Stern N.H.
- Stone D.
- Texas Office of the Governor
- True J.L.
- United States Department of Energy
- Weyland K.
- Yergin D.
- Publication venue
- 'Informa UK Limited'
- Publication date
- Field of study
DAT Genotype Modulates Brain and Behavioral Responses Elicited by Cigarette Cues
- Author
- A Droungas
- A Gratton
- A Heinz
- A Schafer
- A Schienle
- AB Singleton
- AJ Baillie
- AL Brody
- Anna Rose Childress
- AR Childress
- AR Childress
- AR Hariri
- B Sheehan
- CD Salzman
- CH van Dyck
- Charles P O'Brien
- CL Duvauchelle
- D Martinez
- D McBride
- DC Mash
- DE Comings
- Derek Harper
- DF Wong
- DJ Balfour
- DJ Vandenbergh
- DJ Vandenbergh
- DK Lahiri
- DM Small
- EC Hinton
- EP Noble
- Falk W Lohoff
- FE Pontieri
- FJ McClernon
- G Di Chiara
- G Di Chiara
- G Di Chiara
- GD Stuber
- GJ Taylor
- GJ Wang
- GK Aguirre
- H Karlsson
- HM Duvernoy
- I Boileau
- J Erblich
- J Gelernter
- J Mill
- J Yacubian
- JA Detre
- JA Detre
- JA Parkinson
- Jeffrey Cruz
- JM Bjork
- John A Detre
- JR Hughes
- JR Hughes
- KE Hutchison
- KO Fagerstrom
- Kyle Kampman
- LJ Bierut
- M Huber
- M Jaber
- M Kano
- MA Palmatier
- MG Haviland
- Nathan Sciortino
- ND Volkow
- NR Zahniser
- P Di Ciano
- P Wright
- R Stark
- Ron Ehrman
- S Berthoz
- S Fuke
- S Shiffman
- S Shipko
- SH VanNess
- TB Baker
- Teresa R Franklin
- TF Floyd
- TR Franklin
- TR Franklin
- TR Franklin
- V Batra
- W Penny
- WA Alvarez
- WA Corrigall
- Wade Berrettini
- Will Jens
- Yin Li
- Z Wang
- Ze Wang
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Riociguat treatment in patients with pulmonary arterial hypertension: Final safety data from the EXPERT registry
- Author
- Abdelsayed Abeer Abeer
- Acosta Adriana
- Adams Heath
- Agostinho João
- Agostoni Piergiuseppe
- Airò Edoardo
- Al Dalaan Abdullah
- Alexandre Myriam
- Alexeeva Dalyana Eduardovna
- Alfetlawi Monthir
- Almagro Raúl Menor
- Alonso Lecue Pilar
- Altraja Alan
- Andreassen Arne
- Anton Ly
- Argiento Paola
- Arjona Josefa Jiménez
- Asencio Isabel
- Atas Halil
- Avdeev Sergey Nikolaevich
- Avilés Francisco Fernandez
- Badagliacca Roberto
- Baptista Rui
- Barberà Joan
- Barry Lisa
- Bartfay Sven-Erik
- Batalina Marina Vadimovna
- Bauleo Carolina
- Blanco Isabel
- Bohacekova Marcela
- Boogaard H.
- Boomars Karin
- Boonstra Anco
- Bosio Martin
- Bruno Noemi
- Bukatova Irina Fedorovna
- Camacho Rafael Conde
- Campo Felipe
- Caneva Jorge
- Capinha Marta
- Cardoso Tania
- Castro Graça
- Cheng Chin-Chang
- Chu Chun Yuan
- Church Colin
- Cifrián Martínez José Manuel
- Conte Luca
- Correra Anna
- Corris Paul
- Costa Serena
- Cottin Vincent
- Coutinho Daniel
- Cresci Chiara
- Cuesta Victor Mora
- Cárdenas Salvador López
- d'Alto Michele
- d'Armini Andrea Maria
- de la Pava Sebastian
- de Luca Anna
- de Pauw Michel
- Delcroix Marion
- Deleo Sabino
- Di Marco Giovanni Maria
- Diez Mirta
- Dwyer Nathan
- Egenlauf Benjamin
- Elias Teresa
- Escribano Subias Pilar
- Espinha Mafalda
- Evrard Patrick
- Ewert Ralf
- Fanaridis Michail
- Farina Stefania
- Farkasova Iveta
- Farruggio Silvia
- Feenstra John
- Feistmantl Lisa-Theresa
- Fernandez David Iturbe
- Filippov Evgeny Vladimirovich
- Fong Man-Cai
- Gaine Sean
- Galgano Giuseppe
- Gall Henning
- Galyavich Albert Sarvatovich
- Garcea Alessio
- Garcia Alberto
- Garcia Paula
- García Salvador Alcaraz
- Gasche-Soccal Paola
- Georgopoulos Dimitrios
- Gerhardt Felix
- Ghofrani Hossein-Ardeschir
- Giannakoulas George
- Gomez Sanchez Miguel-Angel
- Gomez Juan Esteban
- Grazioli Valentina
- Grimminger Jan
- Gruenberger Margarethe
- Grünig Ekkehard
- Guiot Julien
- Halank Michael
- Hanta Ismail
- Harbaum Lars
- Hegya Daria Viktorovna
- Helmersen Douglas
- Ho Wan-Jing
- Hoeper Marius
- Hsu Chih-Hsin
- Hsu Po-Chao
- Hsu Tsu-Shiu
- Huang Chien-Lung
- Huang Wei-Chun
- Huang Wen-Pin
- Huber Charlotte
- Humbert Marc
- Hung Chi-Sheng
- Ivanov Kyundyul Ivanovich
- Jansa Pavel
- Jara Luis
- Karvounis Haralambos
- Keogh Anne
- Klose Hans
- Klotsche Jens
- Knoop-Busch Susanne
- Kolomeytseva Tatyana Mikhaylovna
- Konstantinides Stavros
- Kotlyar Eugene
- Kotsia Anna
- Kramer Tilmann
- Kulka Christine
- Kuo Ping-Hung
- Kuo Shu-Hung
- Lador Frédéric
- Lai Wen-Ter
- Lang Irene
- Lange Tobias
- Langleben David
- Lavender Melanie
- Lema Camila
- Lin Jiunn-Lee
- Lin Tsung-Hsien
- Lin Yen-Hung
- Lombardi Francesco
- Londoño Alejandro
- Lopez Manuel
- Lopez Raquel
- Louis Renaud
- Loureiro Maria José
- Lunardi Claudio
- Löffler-Ragg Judith
- Mackenzie Michele
- Mager J.
- Maldonado Lorena
- Manzi Giovanna
- Marinho António
- Marrero Fernando León
- Martinez William
- Martinez-Meñaca Amaya
- Martins Jesus Susana Maria
- Martynyuk Tamila Vitalievna
- Massola Giulia
- Mehta Sanjay
- Meier Christian
- Melatini Luciano
- Mellemkjaer Soren
- Michalis Lampros
- Mielniczuk Lisa
- Minson Robert
- Mitrouska Ioanna
- Mouratoglou Sofia
- Mulè Massimiliano
- Mutlu Bülent
- Naldi Marco
- Ndreu Rudina
- Newnham Michael
- Ng Benjamin
- Nielsen-Kudsk Jens Erik
- Nikolaevich Bykov Aleksander
- Nolde Anna
- Noël-Savina Elise
- Okumus Gulfer
- Oliveira Ana
- Olzik Ilona
- Ongen Gul
- Oqueka Tim
- Orozco-Levi Mauricio
- Otero Remedios
- Paciocco Giuseppe
- Pane Federico
- Pappas Athanasios
- Pappas Konstantinos
- Pavlickova Ivana
- Pavlova Olga Borisovna
- Peacock Andrew
- Pepke-Zaba Joanna
- Pesci Alberto
- Petruzzi Mario
- Peñate Gregorio Pérez
- Picariello Claudio
- Piccari Lucilla
- Pin Maurizio
- Pitsiou Georgia
- Pittrow David
- Platonov Dmitry Yurievich
- Poscia Roberto
- Prediletto Renato
- Proudman Susanna
- Quezada Carlos Andres
- Reesink H.
- Reeves Glenn
- Regotta Sabine
- Repolho Débora
- Rocha Andreia
- Rochat Thierry
- Rodríguez Patricia Villanueva
- Roman Antonio
- Roncon Loris
- Rosenkranz Stephan
- Rozas Sonia Fernandez
- Rundqvist Bengt
- Sadushi-Kolici Roela
- Sakkijha Hussam
- Saleemi Sarferaz
- Sardella Luca
- Schulz Christian
- Schwarz Esther Irene
- Sciortino Antonio
- Sebastian Laura
- Shearman Nicole
- Shiang Teresa
- Simon Marcel
- Simonneau Gérald
- Sitbon Olivier
- Skripkina Elena Sergeevna
- Snijder Repke
- Sourla Evdokia
- Sousa Joana
- Speich Rudolf
- Stanopoulos Ioannis
- Steele Peter
- Steringer-Mascherbauer Regina
- Stevens Wendy
- Su Ho-Ming
- Sung Shih-Hsien
- Söderberg Stefan
- Talavera Maria Lujan
- Tania Gonçalves
- Tayler Susanne
- Tilea Ioana
- Torricelli Elena
- Toshner Mark
- Tovar Patricia Parada
- Tregubova Anna Viktorovna
- Tsangaris Iraklis
- Tsareva Natalia Anatolievna
- Tuhay Graciela
- Têtu Laurent
- Ulrich Silvia
- Un Zeynep
- Vachiéry Jean-Luc
- Valkovicova Tatiana
- van den Toorn Leon
- Vannucchi Vieri
- Vasankari Tuija
- Vihinen Tapani
- Vizza Carmine Dario
- Vonk-Noordegraaf A.
- Voon Wen-Chol
- Vulcano Norberto
- Wang Wen-Hwa
- Weheba Ihab
- Williams Evgenia
- Wirtz Gil
- Wirtz Hubert
- Wodlin Peter
- Wu Cho-Kai
- Wu Shu-Hao
- Yakovleva Olga Eduardovna
- Yen Hsueh-Wei
- Yih-Jer Wu Jacob
- Yotti Raquel
- Zvereva Tatyana Nikolaevna
- Šimková Iveta
- Publication venue
- Elsevier
- Publication date
- 01/02/2021
- Field of study
International audienc
Riociguat treatment in patients with chronic thromboembolic pulmonary hypertension: Final safety data from the EXPERT registry
- Author
- Abdelsayed Abeer Abeer
- Acosta Adriana
- Adams Heath
- Agostinho João
- Agostoni Piergiuseppe
- Airò Edoardo
- Al Dalaan Abdullah
- Alexandre Myriam
- Alexeeva Dalyana Eduardovna
- Alfetlawi Monthir
- Almagro Raúl Menor
- Alonso Lecue Pilar
- Altraja Alan
- Andreassen Arne K.
- Anton Ly
- Argiento Paola
- Arjona Josefa Jiménez
- Asencio Isabel
- Atas Halil
- Avdeev Sergey Nikolaevich
- Avilés Francisco Fernandez
- Badagliacca Roberto
- Baptista Rui
- Barberá Joan A.
- Barry Lisa
- Bartfay Sven-Erik
- Batalina Marina Vadimovna
- Bauleo Carolina
- Blanco Isabel
- Bohacekova Marcela
- Boogaard H.
- Boomars Karin
- Boonstra Anco
- Bosio Martin
- Bruno Noemi
- Bukatova Irina Fedorovna
- Camacho Rafael Conde
- Campo Felipe
- Caneva Jorge
- Capinha Marta
- Cardoso Tania
- Castro Graça
- Cheng Chin-Chang
- Chu Chun Yuan
- Church Colin
- Cifrián Martínez José Manuel
- Conte Luca
- Correra Anna
- Corris Paul
- Costa Serena
- Cottin Vincent
- Coutinho Daniel
- Cresci Chiara
- Cuesta Victor Mora
- Cárdenas Salvador López
- D'Alto Michele
- D'Armini Andrea Maria
- De La Pava Sebastian
- De Luca Anna
- De Pauw Michel
- Delcroix Marion
- Deleo Sabino
- Di Marco Giovanni Maria
- Diez Mirta
- Dwyer Nathan
- Egenlauf Benjamin
- Elias Teresa
- Escribano Subias Pilar
- Espinha Mafalda
- Evrard Patrick
- Ewert Ralf
- Fanaridis Michail
- Farina Stefania
- Farkasova Iveta
- Farruggio Silvia
- Feenstra John
- Feistmantl Lisa-Theresa
- Fernandez David Iturbe
- Filippov Evgeny Vladimirovich
- Fong Man-Cai
- Gaine Sean
- Galgano Giuseppe
- Gall Henning
- Galyavich Albert Sarvatovich
- Garcea Alessio
- Garcia Alberto
- Garcia Paula
- García Salvador Alcaraz
- Gasche-Soccal Paola
- Georgopoulos Dimitrios
- Gerhardt Felix
- Ghofrani Hossein-Ardeschir
- Giannakoulas George
- Gomez Sanchez Miguel-Angel
- Gomez Juan Esteban
- Grazioli Valentina
- Grimminger Jan
- Gruenberger Margarethe
- Grünig Ekkehard
- Guiot Julien
- Halank Michael
- Hanta Ismail
- Harbaum Lars
- Hegya Daria Viktorovna
- Helmersen Douglas S.
- Ho Wan-Jing
- Hoeper Marius M.
- Hsu Chih-Hsin
- Hsu Po-Chao
- Hsu Tsu-Shiu
- Huang Chien-Lung
- Huang Wei-Chun
- Huang Wen-Pin
- Huber Charlotte
- Humbert Marc
- Hung Chi-Sheng
- Ivanov Kyundyul Ivanovich
- Jansa Pavel
- Jara Luis
- Karvounis Haralambos
- Keogh Anne
- Klose Hans
- Klotsche Jens
- Knoop-Busch Susanne
- Kolomeytseva Tatyana Mikhaylovna
- Konstantinides Stavros
- Kotlyar Eugene
- Kotsia Anna
- Kramer Tilmann
- Kulka Christine
- Kuo Ping-Hung
- Kuo Shu-Hung
- Lador Frédéric
- Lai Wen-Ter
- Lang Irene
- Lange Tobias J.
- Langleben David
- Lavender Melanie
- Lema Camila
- Lin Jiunn-Lee
- Lin Tsung-Hsien
- Lin Yen-Hung
- Lombardi Francesco
- Londoño Alejandro
- Lopez Manuel
- Lopez Raquel
- Louis Renaud
- Loureiro Maria José
- Lunardi Claudio
- Löffler-Ragg Judith
- Mackenzie Michele
- Mager J.
- Maldonado Lorena
- Manzi Giovanna
- Marinho António
- Marrero Fernando León
- Martinez William
- Martinez-Meñaca Amaya
- Martins Jesus Susana Maria
- Martynyuk Tamila Vitalievna
- Massola Giulia
- Mehta Sanjay
- Meier Christian
- Melatini Luciano
- Mellemkjaer Soren
- Michalis Lampros
- Mielniczuk Lisa M.
- Minson Robert
- Mitrouska Ioanna
- Mouratoglou Sofia
- Mulè Massimiliano
- Mutlu Bülent
- Naldi Marco
- Ndreu Rudina
- Newnham Michael
- Ng Benjamin
- Nielsen-Kudsk Jens Erik
- Nikolaevich Bykov Aleksander
- Nolde Anna
- Noël-Savina Elise
- Okumus Gulfer
- Oliveira Ana
- Olzik Ilona
- Ongen Gul
- Oqueka Tim
- Orozco-Levi Mauricio
- Otero Remedios
- Paciocco Giuseppe
- Pane Federico
- Pappas Athanasios
- Pappas Konstantinos
- Pavlickova Ivana
- Pavlova Olga Borisovna
- Peacock Andrew
- Pepke-Zaba Joanna
- Pesci Alberto
- Petruzzi Mario
- Peñate Gregorio Pérez
- Picariello Claudio
- Piccari Lucilla
- Pin Maurizio
- Pitsiou Georgia
- Pittrow David
- Platonov Dmitry Yurievich
- Poscia Roberto
- Prediletto Renato
- Proudman Susanna
- Quezada Carlos Andres
- Reesink H.
- Reeves Glenn
- Regotta Sabine
- Repolho Débora
- Rocha Andreia
- Rochat Thierry
- Rodríguez Patricia Villanueva
- Roman Antonio
- Roncon Loris
- Rosenkranz Stephan
- Rozas Sonia Fernandez
- Rundqvist Bengt
- Sadushi-Kolici Roela
- Sakkijha Hussam
- Saleemi Sarferaz
- Sardella Luca
- Schulz Christian
- Schwarz Esther Irene
- Sciortino Antonio
- Sebastian Laura
- Shearman Nicole
- Shiang Teresa
- Simon Marcel
- Simonneau Gérald
- Sitbon Olivier
- Skripkina Elena Sergeevna
- Snijder Repke J.
- Sourla Evdokia
- Sousa Joana
- Speich Rudolf
- Stanopoulos Ioannis
- Steele Peter
- Steringer-Mascherbauer Regina
- Stevens Wendy
- Su Ho-Ming
- Sung Shih-Hsien
- Söderberg Stefan
- Talavera Maria Lujan
- Tania Gonçalves
- Tayler Susanne
- Tilea Ioana
- Torricelli Elena
- Toshner Mark
- Tovar Patricia Parada
- Tregubova Anna Viktorovna
- Tsangaris Iraklis
- Tsareva Natalia Anatolievna
- Tuhay Graciela
- Têtu Laurent
- Ulrich Silvia
- Un Zeynep
- Un Zeynep
- Vachiéry Jean-Luc
- Valkovicova Tatiana
- van den Toorn Leon M.
- Vannucchi Vieri
- Vasankari Tuija
- Vihinen Tapani
- Vizza Carmine Dario
- Vonk-Noordegraaf A.
- Voon Wen-Chol
- Vulcano Norberto
- Wang Wen-Hwa
- Weheba Ihab
- Williams Evgenia
- Wirtz Gil
- Wirtz Hubert
- Wodlin Peter
- Wu Cho-Kai
- Wu Shu-Hao
- Yakovleva Olga Eduardovna
- Yen Hsueh-Wei
- Yih-Jer Wu Jacob
- Yotti Raquel
- Zvereva Tatyana Nikolaevna
- Šimková Iveta
- Publication venue
- W B SAUNDERS CO LTD
- Publication date
- 01/01/2021
- Field of study
Objective: The soluble guanylate cyclase stimulator riociguat is approved for the treatment of adult patients with pulmonary arterial hypertension (PAH) and inoperable or persistent/recurrent chronic thromboembolic pulmonary hypertension (CTEPH) following Phase 3 randomized trials. The EXPosurE Registry RiociguaT in patients with pulmonary hypertension (EXPERT) study was designed to monitor the long-term safety of riociguat in clinical practice. Methods: EXPERT was an international, multicenter, prospective, uncontrolled, non-interventional cohort study of patients treated with riociguat. Patients were followed for at least 1 year and up to 4 years from enrollment or until 30 days after stopping riociguat treatment. Primary safety outcomes were adverse events (AEs) and serious adverse events (SAEs) coded using Medical Dictionary for Regulatory Activities preferred terms and System Organ Classes version 21.0, collected during routine clinic visits and collated via case report forms. Results: In total, 956 patients with CTEPH were included in the analysis. The most common AEs in these patients were peripheral edema/edema (11.7%), dizziness (7.5%), right ventricular (RV)/cardiac failure (7.7%), and pneumonia (5.0%). The most common SAEs were RV/cardiac failure (7.4%), pneumonia (4.1%), dyspnea (3.6%), and syncope (2.5%). Exposure-adjusted rates of hemoptysis/pulmonary hemorrhage and hypotension were low and comparable to those in the long-term extension study of riociguat (Chronic Thromboembolic Pulmonary Hypertension Soluble Guanylate Cyclase-Stimulator Trial [CHEST-2]). Conclusion: Data from EXPERT show that in patients with CTEPH, the safety of riociguat in routine practice was consistent with the known safety profile of the drug, and no new safety concerns were identified
Riociguat treatment in patients with chronic thromboembolic pulmonary hypertension: Final safety data from the EXPERT registry
- Author
- Abdelsayed Abeer Abeer
- Acosta Adriana
- Adams Heath
- Agostinho João
- Agostoni Piergiuseppe
- Airò Edoardo
- Al Dalaan Abdullah
- Alexandre Myriam
- Alexeeva Dalyana Eduardovna
- Alfetlawi Monthir
- Almagro Raúl Menor
- Alonso Lecue Pilar
- Altraja Alan
- Andreassen Arne
- Anton Ly
- Argiento Paola
- Arjona Josefa Jiménez
- Asencio Isabel
- Atas Halil
- Avdeev Sergey Nikolaevich
- Avilés Francisco Fernandez
- Badagliacca Roberto
- Baptista Rui
- Barberá Joan
- Barry Lisa
- Bartfay Sven-Erik
- Batalina Marina Vadimovna
- Bauleo Carolina
- Blanco Isabel
- Bohacekova Marcela
- Boogaard H.
- Boomars Karin
- Boonstra Anco
- Bosio Martin
- Bruno Noemi
- Bukatova Irina Fedorovna
- Camacho Rafael Conde
- Campo Felipe
- Caneva Jorge
- Capinha Marta
- Cardoso Tania
- Castro Graça
- Cheng Chin-Chang
- Chu Chun Yuan
- Church Colin
- Cifrián Martínez José Manuel
- Conte Luca
- Correra Anna
- Corris Paul
- Costa Serena
- Cottin Vincent
- Coutinho Daniel
- Cresci Chiara
- Cuesta Victor Mora
- Cárdenas Salvador López
- d'Alto Michele
- d'Armini Andrea Maria
- de la Pava Sebastian
- de Luca Anna
- de Pauw Michel
- Delcroix Marion
- Deleo Sabino
- Di Marco Giovanni Maria
- Diez Mirta
- Dwyer Nathan
- Egenlauf Benjamin
- Elias Teresa
- Escribano Subias Pilar
- Espinha Mafalda
- Evrard Patrick
- Ewert Ralf
- Fanaridis Michail
- Farina Stefania
- Farkasova Iveta
- Farruggio Silvia
- Feenstra John
- Feistmantl Lisa-Theresa
- Fernandez David Iturbe
- Filippov Evgeny Vladimirovich
- Fong Man-Cai
- Gaine Sean
- Galgano Giuseppe
- Gall Henning
- Galyavich Albert Sarvatovich
- Garcea Alessio
- Garcia Alberto
- Garcia Paula
- García Salvador Alcaraz
- Gasche-Soccal Paola
- Georgopoulos Dimitrios
- Gerhardt Felix
- Ghofrani Hossein-Ardeschir
- Giannakoulas George
- Gomez Sanchez Miguel-Angel
- Gomez Juan Esteban
- Grazioli Valentina
- Grimminger Jan
- Gruenberger Margarethe
- Grünig Ekkehard
- Guiot Julien
- Halank Michael
- Hanta Ismail
- Harbaum Lars
- Hegya Daria Viktorovna
- Helmersen Douglas
- Ho Wan-Jing
- Hoeper Marius
- Hsu Chih-Hsin
- Hsu Po-Chao
- Hsu Tsu-Shiu
- Huang Chien-Lung
- Huang Wei-Chun
- Huang Wen-Pin
- Huber Charlotte
- Humbert Marc
- Hung Chi-Sheng
- Ivanov Kyundyul Ivanovich
- Jansa Pavel
- Jara Luis
- Karvounis Haralambos
- Keogh Anne
- Klose Hans
- Klotsche Jens
- Knoop-Busch Susanne
- Kolomeytseva Tatyana Mikhaylovna
- Konstantinides Stavros
- Kotlyar Eugene
- Kotsia Anna
- Kramer Tilmann
- Kulka Christine
- Kuo Ping-Hung
- Kuo Shu-Hung
- Lador Frédéric
- Lai Wen-Ter
- Lang Irene
- Lange Tobias
- Langleben David
- Lavender Melanie
- Lema Camila
- Lin Jiunn-Lee
- Lin Tsung-Hsien
- Lin Yen-Hung
- Lombardi Francesco
- Londoño Alejandro
- Lopez Manuel
- Lopez Raquel
- Louis Renaud
- Loureiro Maria José
- Lunardi Claudio
- Löffler-Ragg Judith
- Mackenzie Michele
- Mager J.
- Maldonado Lorena
- Manzi Giovanna
- Marinho António
- Marrero Fernando León
- Martinez William
- Martinez-Meñaca Amaya
- Martins Jesus Susana Maria
- Martynyuk Tamila Vitalievna
- Massola Giulia
- Mehta Sanjay
- Meier Christian
- Melatini Luciano
- Mellemkjaer Soren
- Michalis Lampros
- Mielniczuk Lisa
- Minson Robert
- Mitrouska Ioanna
- Mouratoglou Sofia
- Mulè Massimiliano
- Mutlu Bülent
- Naldi Marco
- Ndreu Rudina
- Newnham Michael
- Ng Benjamin
- Nielsen-Kudsk Jens Erik
- Nikolaevich Bykov Aleksander
- Nolde Anna
- Noël-Savina Elise
- Okumus Gulfer
- Oliveira Ana
- Olzik Ilona
- Ongen Gul
- Oqueka Tim
- Orozco-Levi Mauricio
- Otero Remedios
- Paciocco Giuseppe
- Pane Federico
- Pappas Athanasios
- Pappas Konstantinos
- Pavlickova Ivana
- Pavlova Olga Borisovna
- Peacock Andrew
- Pepke-Zaba Joanna
- Pesci Alberto
- Petruzzi Mario
- Peñate Gregorio Pérez
- Picariello Claudio
- Piccari Lucilla
- Pin Maurizio
- Pitsiou Georgia
- Pittrow David
- Platonov Dmitry Yurievich
- Poscia Roberto
- Prediletto Renato
- Proudman Susanna
- Quezada Carlos Andres
- Reesink H.
- Reeves Glenn
- Regotta Sabine
- Repolho Débora
- Rocha Andreia
- Rochat Thierry
- Rodríguez Patricia Villanueva
- Roman Antonio
- Roncon Loris
- Rosenkranz Stephan
- Rozas Sonia Fernandez
- Rundqvist Bengt
- Sadushi-Kolici Roela
- Sakkijha Hussam
- Saleemi Sarferaz
- Sardella Luca
- Schulz Christian
- Schwarz Esther Irene
- Sciortino Antonio
- Sebastian Laura
- Shearman Nicole
- Shiang Teresa
- Simon Marcel
- Simonneau Gérald
- Sitbon Olivier
- Skripkina Elena Sergeevna
- Snijder Repke
- Sourla Evdokia
- Sousa Joana
- Speich Rudolf
- Stanopoulos Ioannis
- Steele Peter
- Steringer-Mascherbauer Regina
- Stevens Wendy
- Su Ho-Ming
- Sung Shih-Hsien
- Söderberg Stefan
- Talavera Maria Lujan
- Tania Gonçalves
- Tayler Susanne
- Tilea Ioana
- Torricelli Elena
- Toshner Mark
- Tovar Patricia Parada
- Tregubova Anna Viktorovna
- Tsangaris Iraklis
- Tsareva Natalia Anatolievna
- Tuhay Graciela
- Têtu Laurent
- Ulrich Silvia
- Un Zeynep
- Un Zeynep
- Vachiéry Jean-Luc
- Valkovicova Tatiana
- van den Toorn Leon
- Vannucchi Vieri
- Vasankari Tuija
- Vihinen Tapani
- Vizza Carmine Dario
- Vonk-Noordegraaf A.
- Voon Wen-Chol
- Vulcano Norberto
- Wang Wen-Hwa
- Weheba Ihab
- Williams Evgenia
- Wirtz Gil
- Wirtz Hubert
- Wodlin Peter
- Wu Cho-Kai
- Wu Shu-Hao
- Yakovleva Olga Eduardovna
- Yen Hsueh-Wei
- Yih-Jer Wu Jacob
- Yotti Raquel
- Zvereva Tatyana Nikolaevna
- Šimková Iveta
- Publication venue
- Elsevier
- Publication date
- 01/03/2021
- Field of study
International audienc