CROSS-SECTIONAL STUDY OF ASSOCIATION BETWEEN GLYCEMIC CONTROL AND QUALITY OF LIFE AMONG DIABETIC PATIENTS

Objective: The present study aimed to evaluate the association between glycemic control and quality of life (QoL) in people with type 2 diabetesmellitus (T2DM) and identify that factors that influence glycemic control and QoL.Methods: This cross-sectional study was conducted at the general hospital in Depok City from October to December 2017. Respondents wereoutpatients diagnosed with T2DM, receiving routine care at the hospital. Glycemic control was assessed using glycated hemoglobin (HbA1c) levels,while QoL was measured using an Indonesian version of the validated 5-level EuroQol 5-Dimensional.Results: Among 108 participants, HbA1c levels were influenced by age, DM disease duration, DM treatment adherence, glycemic control, diet, andphysical activity suitable for patients with DM. The mean QoL value was 0.74±0.23 and the visual analog scale (VAS) score was 65.49±15.96. The QoLvalues of patients with DM were influenced by HbA1c levels, duration of DM, and physical activity, while the VAS score was significantly affected byHbA1c levels and duration of DM.Conclusion: The present study showed that the QoL of T2DM patients was significantly influenced by glycemic control and other factors

UJI AKTIVITAS ANTI BAKTERI EKSTRAK ETANOL DAUN KEMANGI (Ocimum sanctum L.) TERHADAP PERTUMBUHAN BAKTERI Staphylococcus aureus SECARA IN VITRO

Penyakit infeksi merupakan salah satu penyebab morbiditas dan mortalitas penduduk dunia yang menyebabkan penurunan kualitas hidup penduduk di negara berkembang maupun di negara maju. Salah satu agen penyebab infeksi adalah bakteri Staphylococcus aureus (S. aureus). Oleh sebab itu, dibutuhkan pengobatan terhadap infeksi yang disebabkan oleh Staphylococcus aureus dengan menggunakan antibiotik. Namun apabila penggunaan antibiotik tidak tepat maka akan menimbulkan resistensi antibiotik. Oleh sebab itu, diperlukan pengobatan alternatif lainnya yaitu pengobatan menggunakan tanaman herbal. Salah satu tumbuhan yang dapat digunakan sebagai tanaman obat adalah daun kemangi (Ocimum sanctum L.). Tujuan penelitian ini untuk mengetahui aktivitas antibakteri ekstrak daun kemangi terhadap pertumbuhan Staphylococcus aureus. Metode penelitian True experiment design dengan rancangan penelitian Posstest Only Control Group Design. Aktivitas antibakteri ekstrak etanol 70% daun kemangi diuji menggunakan metode dilusi cair. Sampel penelitian terdiri dari 9 kelompok perlakuan terdiri atas kontrol positif (sefazolin), kontrol negatif (aquades),ekstrak etanol 70% daun kemangi dengan konsentrasi 100%, 80%, 70%, 40%, 20%, 10%, dan 5% dengan tiga kali pengulangan. Hasil Uji Kolmogorov Smirnov menunjukkan p=0,194 yang berarti terdapat aktivitas antibakteri ekstrak etanol 70% daun kemangi terhadap bakteri Staphylococcus aureus. Kesimpulan dari penelitian ini ekstrak etanol 70% daun kemangi (Ocimum sanctum L.) memiliki aktivitas antibakteri terhadap Staphylococcus aureus dengan nilai Konsentrasi Hambat Minimum (KHM) dan Konsentrasi Bunuh Minimum (KBM) berturut-turut sebesar 80% dan 100%

Analisis Kualitas Eco-enzyme Berdasarkan Perbedaan Jaringan Tumbuhan

This research is focused on analyzing the quality of eco-enzymes based on differences in plant tissue on organic matter in the manufacture of eco-enzymes. The purpose of this study was to compare the quality of eco-enzymes made from pineapple peel (dominated by epidermal tissue) and pineapple flesh (dominated by parenchyma tissue). This research method is an experimental method with 3 repetitions. This research was conducted from June 3, 2021, to July 3, 2021. Pineapple peel and pineapple flesh each with a ratio of 3 parts (as organic matter) were mixed with 1 part molasses and 10 parts clean water, then fermented for 1 month. Samples of eco-enzymes from pineapple peel and pineapple flesh were analyzed to compare the research parameters in the form of color, organic conditions, the position of organic matter, aroma, presence of pitera mushrooms, and pH. The results showed that the eco-enzyme gave rise to different parameters but both had good quality. However, in this study the eco-enzyme that had better quality was the eco-enzyme derived from pineapple flesh (dominated by parenchyma tissue). So, it can be said that the eco-enzyme produced from tissue dominated by parenchyma tissue has better quality than that which is dominated by epidermal tissue.Penelitian ini difokuskan untuk menganalisis kualitas eco-enzyme berdasarkan perbedaan jaringan tumbuhan terhadap bahan organik dalam pembuatan eco-enzyme. Tujuan dari penelitian ini adalah untuk membandingkan kualitas eco-enzyme yang dibuat dari kulit nanas (didominasi oleh jaringan epidermis) dan daging nanas (didominasi oleh jaringan parenkim). Metode penelitian ini adalah metode eksperimen dengan 3 kali pengulangan. Penelitian ini dilaksanakan mulai tanggal 3 Juni 2021 sampai dengan 3 Juli 2021. Kulit nanas dan daging buah nanas masing-masing dengan perbandingan 3 bagian (sebagai bahan organik) dicampur dengan 1 bagian tetes tebu dan 10 bagian air bersih, kemudian difermentasi selama 1 bulan. . Sampel eco-enzyme dari kulit nanas dan daging nanas dianalisis untuk membandingkan parameter penelitian berupa warna, kondisi organik, posisi bahan organik, aroma, keberadaan jamur pitera, dan pH. Hasil penelitian menunjukkan bahwa eco-enzyme memunculkan parameter yang berbeda tetapi keduanya memiliki kualitas yang baik. Namun pada penelitian ini eco-enzyme yang memiliki kualitas lebih baik adalah eco-enzyme yang berasal dari daging buah nanas (didominasi oleh jaringan parenkim). Sehingga dapat dikatakan bahwa eco-enzyme yang dihasilkan dari jaringan yang didominasi oleh jaringan parenkim memiliki kualitas yang lebih baik daripada yang didominasi oleh jaringan epidermis

Improving ammonium sorption of Bayah natural zeolites by hydrothermal method

Natural zeolites are easily found and abundant in Indonesia. The natural zeolites are low-cost minerals; however, their ammonium sorption is poor. A hydrothermal method was applied to improve the ammonium sorption. Hydrothermal treatment times were varied 8, 24, and 32 h. The parent and hydrothermal treated samples were characterized by using X-ray diffraction (XRD), Field Emission Scanning Electron Microscopes (FE-SEM), Fourier-transform infrared spectroscopy (FTIR), and nitrogen physisorption. Ammonium adsorption was performed using a batch reactor to evaluate the adsorption performance of the prepared zeolite samples. The 8 h hydrothermal (HT 8 h) treated zeolites showed the highest ammonium removal percentage among others. The XRD analysis of HT 8 h shows a higher crystallinity of mordenite and the Brunauer–Emmett–Teller (BET) model shows a surface area of 105 m2 /g, much larger as compared to the parent with a surface area of 19 m2 /g. Various kinetic and isotherms models were also studied on the parent and HT 8 h samples. The intraparticle equation showed the most accurate model for the kinetic data and the Freundlich equation showed the most accurate model for the isotherm of the experimental data. In terms of ammonium removal efficiency, hydrothermally treated Bayah mordenite compares favorably with treated mordenite from other locations despite that clinoptilolite provides higher removal capacities than mordenite