Preeclampsia and diuresis criteria: our experience at the University of Iowa Hospitals and Clinics

Preeclampsia is a multisystem disorder that complicates approximately 5-8% of pregnancies. It is known that the clinical manifestations of preeclampsia are a result of widespread vasoconstriction. It is therefore thought that the onset of diuresis may signal a reversal of this vasoconstriction, and thus resolution of the disease. This retrospective cohort study was conducted at the University of Iowa Hospitals and Clinics (UIHC) to validate our diuresis criteria and determine if there was a trend for diuresis that was dependent on the type of preeclampsia. This study suggests that the diuresis curves for those women with mild preeclampsia and severe preeclampsia do not vary significantly after the first 5 hours We were able to separate the women with severe preeclampsia into two groups, one of which would have met our diuresis criteria prior to 24 hours and the other of which would not have met diuresis criteria at 24 hours post-delivery

Planck 2015 results. XX. Constraints on inflation

We present the implications for cosmic inflation of the Planck measurements of the cosmic microwave background (CMB) anisotropies in both temperature and polarization based on the full Planck survey. The Planck full mission temperature data and a first release of polarization data on large angular scales measure the spectral index of curvature perturbations to be n s = 0.968 ± 0.006 and tightly constrain its scale dependence to dn s /dlnk = −0.003 ± 0.007 when combined with the Planck lensing likelihood. When the high-ℓ polarization data is included, the results are consistent and uncertainties are reduced. The upper bound on the tensor-to-scalar ratio is r 0.002 <0.11 (95% CL), consistent with the B-mode polarization constraint r<0.12 (95% CL) obtained from a joint BICEP2/Keck Array and Planck analysis. These results imply that V(ϕ)∝ϕ 2 and natural inflation are now disfavoured compared to models predicting a smaller tensor-to-scalar ratio, such as R 2 inflation. Three independent methods reconstructing the primordial power spectrum are investigated. The Planck data are consistent with adiabatic primordial perturbations. We investigate inflationary models producing an anisotropic modulation of the primordial curvature power spectrum as well as generalized models of inflation not governed by a scalar field with a canonical kinetic term. The 2015 results are consistent with the 2013 analysis based on the nominal mission data