649 research outputs found
Intermediate expression of CCRL1 reveals novel subpopulations of medullary thymic epithelial cells that emerge in the postnatal thymus.
- Publication venue
- 'Wiley'
- Publication date
- 01/01/2014
- Field of study
Cortical and medullary thymic epithelial cells (cTECs and mTECs, respectively) provide inductive microenvironments for T-cell development and selection. The differentiation pathway of cTEC/mTEC lineages downstream of common bipotent progenitors at discrete stages of development remains unresolved. Using IL-7/CCRL1 dual reporter mice that identify specialized TEC subsets, we show that the stepwise acquisition of chemokine (C-C motif) receptor-like 1 (CCRL1) is a late determinant of cTEC differentiation. Although cTECs expressing high CCRL1 levels (CCRL1(hi) ) develop normally in immunocompetent and Rag2(-/-) thymi, their differentiation is partially blocked in Rag2(-/-) Il2rg(-/-) counterparts. These results unravel a novel checkpoint in cTEC maturation that is regulated by the cross-talk between TECs and immature thymocytes. Additionally, we identify new Ulex europaeus agglutinin 1 (UEA)(+) mTEC subtypes expressing intermediate CCRL1 levels (CCRL1(int) ) that conspicuously emerge in the postnatal thymus and differentially express Tnfrsf11a, Ccl21, and Aire. While rare in fetal and in Rag2(-/-) thymi, CCRL1(int) mTECs are restored in Rag2(-/-) Marilyn TCR-Tg mice, indicating that the appearance of postnatal-restricted mTECs is closely linked with T-cell selection. Our findings suggest that alternative temporally restricted routes of new mTEC differentiation contribute to the establishment of the medullary niche in the postnatal thymus.We thank James Di Santo, Jocelyne Demengeot, and Thomas Boehm for Rag2−/−Il2rg−/−, CCRL1-reporter, and Marilyn-Rag2−/− mice, respectively. We thank Dr. Catarina Leit˜ao for critical reading of the manuscript and technical assistance. We thank FEDER funds through the Operational Competitiveness Programme – COMPETE and by National Funds through Fundaçao para a Ciência e a Tecnologia (FCT) under the project PTDC/SAU-IMU/117057/2010 funded this work. N.L.A., A.R.R.,C.M., and P.M.R. are supported by FCT Investigator program and PhD fellowships
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Dissecting celastrol with machine learning to unveil dark pharmacology
- Publication venue
- Chemical Communications
- Publication date
- 30/05/2019
- Field of study
Coallescing bespoke machine learning and bioinformatics analyses with cell-based assays we unveil pharmacology of celastrol. Celastrol is a direct modulator of the progesterone and cannabinoid receptors, and its effects correlate with the antiproliferative activity. We demonstrate how in silico methods may drive systems biology studies for natural products.We thank the Royal Society (URF\R\180019), H2020 (ERC StG, GA no. 676832, 743640 ad 807281) and FCT Portugal (IF/00624/2015 and 02/SAICT/2017, Grant 28333) for funding
Looking backward: From Euler to Riemann
- Author
- A Papadopoulos
- A Weil
- A Weil
- AB Kempe
- AB Niewenglowski
- AP Youschkevitch
- AW Knapp
- B Riemann
- B Riemann
- B Riemann
- B Riemann
- C Huffman
- CF Gauss
- GH Moore
- GW Leibniz
- H Grassmann
- H Lebesgue
- H Lebesgue
- H Poincaré
- I Kant
- J Dutka
- J-C Pont
- J-L-F Bertrand
- J-M Thiel
- J-P-F Valat
- JD Gergonne
- KA Andreiev
- L Poinsot
- L Poinsot
- LJ Goldstein
- LV Ahlfors
- M Feil
- NH Abel
- NL Biggs
- NV Bougaïev
- O Rodrigues
- P Appell
- P Carus
- P Hilton
- P-M-E Prouhet
- P-M-E Prouhet
- PH Fuss
- R Descartes
- R Remmert
- R Thom
- S-A-J Lhuillier
- S-D Poisson
- WP Thurston
- É Picard
- Publication venue
- Publication date
- 11/10/2017
- Field of study
We survey the main ideas in the early history of the subjects on which
Riemann worked and that led to some of his most important discoveries. The
subjects discussed include the theory of functions of a complex variable,
elliptic and Abelian integrals, the hypergeometric series, the zeta function,
topology, differential geometry, integration, and the notion of space. We shall
see that among Riemann's predecessors in all these fields, one name occupies a
prominent place, this is Leonhard Euler. The final version of this paper will
appear in the book \emph{From Riemann to differential geometry and relativity}
(L. Ji, A. Papadopoulos and S. Yamada, ed.) Berlin: Springer, 2017
Subdominant/Cryptic CD8 T Cell Epitopes Contribute to Resistance against Experimental Infection with a Human Protozoan Parasite
- Author
- AC Oliveira
- AF Araújo
- Alexandre V. Machado
- AM Padilla
- AV Machado
- BC de Alencar
- Bruna C. G. de Alencar
- C Claser
- C Junqueira
- CS Rosenberg
- DC Wilson
- DL Martin
- Eduardo L. V. Silveira
- EM Frickel
- F Kierszenbaum
- F Tzelepis
- F Tzelepis
- F Tzelepis
- FA Haolla
- FR Gutierrez
- Georges Snounou
- J Lannes-Vieira
- J Scharfstein
- J Schneider
- JA Marin-Neto
- JB Sacha
- José Ronnie C. de Vasconcelos
- JR Vasconcelos
- JW Yewdell
- K Irvine
- KA Kumar
- KM Bonney
- L Freire-de-Lima
- LM Bixby
- M Mauduit
- M Oukka
- M Rodrigues
- M Rodrigues
- M Sedegah
- Mariana R. Dominguez
- Mauricio M. Rodrigues
- MF Kotturi
- MH Newberg
- MM Rodrigues
- MR Jenkins
- N Blanchard
- ND MacHugh
- NL La Gruta
- NL La Gruta
- Oscar Bruna-Romero
- P Riedl
- R Holtappels
- RA Willis
- Ricardo T. Gazzinelli
- RL Tarleton
- S Li
- S Tenzer
- SB Boscardin
- SI Cazorla
- TC Friedrich
- TJ Ruckwardt
- V Pavelic
- W Chen
- W Chen
- W Kastenmuller
- Y Miyahira
- Publication venue
- Public Library of Science
- Publication date
- 01/01/2011
- Field of study
During adaptive immune response, pathogen-specific CD8+ T cells recognize preferentially a small number of epitopes, a phenomenon known as immunodominance. Its biological implications during natural or vaccine-induced immune responses are still unclear. Earlier, we have shown that during experimental infection, the human intracellular pathogen Trypanosoma cruzi restricts the repertoire of CD8+ T cells generating strong immunodominance. We hypothesized that this phenomenon could be a mechanism used by the parasite to reduce the breath and magnitude of the immune response, favoring parasitism, and thus that artificially broadening the T cell repertoire could favor the host. Here, we confirmed our previous observation by showing that CD8+ T cells of H-2a infected mice recognized a single epitope of an immunodominant antigen of the trans-sialidase super-family. In sharp contrast, CD8+ T cells from mice immunized with recombinant genetic vaccines (plasmid DNA and adenovirus) expressing this same T. cruzi antigen recognized, in addition to the immunodominant epitope, two other subdominant epitopes. This unexpected observation allowed us to test the protective role of the immune response to subdominant epitopes. This was accomplished by genetic vaccination of mice with mutated genes that did not express a functional immunodominant epitope. We found that these mice developed immune responses directed solely to the subdominant/cryptic CD8 T cell epitopes and a significant degree of protective immunity against infection mediated by CD8+ T cells. We concluded that artificially broadening the T cell repertoire contributes to host resistance against infection, a finding that has implications for the host-parasite relationship and vaccine development
Validation of a stroke symptom questionnaire for epidemiological surveys
- Author
- Alessandra Carvalho Goulart
- André C
- Berger K
- Cabral NL
- Cabral NL
- Carod-Artal FJ
- Carod-Artal FJ
- Carod-Artal FJ
- Christensen MC
- Gomes MM
- Goulart AC
- Isabela Martins Benseñor
- Ivana Makita Abe
- Landis JR
- Lessa I
- Lessa. I.
- Lolio CA
- Lotufo PA
- Lotufo PA
- Lotufo PA
- Lotufo PA
- Melcon CM
- Meneghini F
- Meneghini F
- Meschia JF
- Minelli C
- Monteiro CA
- Nicoletti A
- Paulo Andrade Lotufo
- Pereira ABCNG
- Truelsen T
- Truelsen T
- Waldyr Rodrigues Santos Júnior
- Publication venue
- 'FapUNIFESP (SciELO)'
- Publication date
- Field of study
Micromorphology of Paleosols of the Marília Formation and their Significance in the Paleoenvironmental Evolution of the Bauru Basin, Upper Cretaceous, Southeastern Brazil
- Author
- Alessandro Batezelli
- Amaral G
- Andreis RR
- Batezelli A
- Batezelli A
- Batezelli A
- Batezelli A
- Bedelean H
- Birkeland PW
- Brown TM
- Bullock P
- Castro SS
- Catt JA
- Delvigne JE
- Dias-Brito D
- Durand N
- Fernandes LA
- Fernandes LA
- Fernandes LA
- Fitzpatrick EA
- Fragoso CE
- Francisco Sérgio Bernardes Ladeira
- Fulfaro VJ
- Fulfaro VJ
- Gile LH
- Gobbo-Rodrigues RS
- Guimarães GB
- Hartley AJ
- Hasui Y
- Kosir A
- Kraus MJ
- Kraus MJ
- Machado Junior DL
- Machette MN
- Manafi S
- Marriott SB
- Martinelli AG
- Mccarthy P
- Márcio Luiz da Silva
- Nascimento NL
- Paula and Silva F
- Pimentel NL
- Porta J
- Retallack GJ
- Retallack GJ
- Riccomini C
- Riccomini C
- Santos RD
- Santucci RM
- Sheldon ND
- Singer A
- Sonoki IK
- Stanistreet I
- Stoops G
- Stoops G
- Stoops G
- Stoops G
- Wright VP
- Wright VP
- Publication venue
- 'FapUNIFESP (SciELO)'
- Publication date
- 01/01/2017
- Field of study
TRY plant trait database - enhanced coverage and open access
- Author
- Aakala T
- Abedi M
- Acosta ATR
- Adamidis GC
- Adamson K
- Aiba M
- Albert CH
- Alcantara JM
- Alcazar CC
- Aleixo I
- Ali H
- Amiaud B
- Ammer C
- Amoroso MM
- Anand M
- Anderson C
- Anh TDL
- Anten N
- Antos J
- Apgaua DMG
- Ashman TL
- Asmara DH
- Asner GP
- Aspinwall M
- Atkin O
- Aubin I
- Baastrup-Spohr L
- Bahalkeh K
- Bahn M
- Baker T
- Baker WJ
- Bakker JP
- Baldocchi D
- Baltzer J
- Banerjee A
- Baranger A
- Barlow J
- Barneche DR
- Baruch Z
- Bastianelli D
- Battles J
- Bauerle W
- Bauters M
- Bazzato E
- Beckmann M
- Beeckman H
- Beierkuhnlein C
- Bekker R
- Belfry G
- Belluau M
- Beloiu M
- Benavides R
- Benomar L
- Berdugo-Lattke ML
- Berenguer E
- Bergamin R
- Bergmann J
- Berner L
- Bernhardt-Romermann M
- Bigler C
- Bjorkman AD
- Blackman C
- Blanco C
- Blonder B
- Blumenthal D
- Bocanegra-Gonzalez KT
- Boeckx P
- Bohlman S
- Bohning-Gaese K
- Boisvert-Marsh L
- Bond W
- Bond-Lamberty B
- Bonisch G
- Boom A
- Boonman CCF
- Bordin K
- Boughton EH
- Boukili V
- Bowman DMJS
- Bravo S
- Brendel MR
- Broadley MR
- Brown KA
- Bruelheide H
- Brumnich F
- Bruun HH
- Bruy D
- Buchanan SW
- Bucher SF
- Buchmann N
- Buitenwerf R
- Bunker DE
- Burger J
- Burrascano S
- Burslem DFRP
- Butterfield BJ
- Byun C
- Caccianiga M
- Cadotte M
- Cailleret M
- Camac J
- Camarero JJ
- Campany C
- Campetella G
- Campos JA
- Cano-Arboleda L
- Canullo R
- Carbognani M
- Carlucci MB
- Carvalho F
- Casanoves F
- Castagneyrol B
- Catford JA
- Cavender-Bares J
- Cerabolini BEL
- Cervellini M
- Chacon-Madrigal E
- Chapin FS
- Chapin K
- Chelli S
- Chen AP
- Chen SC
- Cherubini P
- Chianucci F
- Choat B
- Chung KS
- Chytry M
- Ciccarelli D
- Coll L
- Collins CG
- Conti L
- Coomes D
- Cornelissen JHC
- Cornwell WK
- Corona P
- Coyea M
- Craine J
- Craven D
- Cromsigt JPGM
- Csecserits A
- Cufar K
- Cuntz M
- da Silva AC
- Dahlin KM
- Dainese M
- Dalke I
- Dalle Fratte M
- Danihelka J
- Dannoura M
- Dawson S
- de Beer AJ
- de Dios VR
- De Frutos A
- de Gasper AL
- De Long JR
- Dechant B
- Delagrange S
- Delpierre N
- Derroire G
- Dias AS
- Diaz S
- Diaz-Toribio MH
- Dimitrakopoulos PG
- Dobrowolski M
- Doktor D
- Domingues TF
- Dong N
- Dransfield J
- Dressler S
- Drevojan P
- Duarte L
- Ducouret E
- Dullinger S
- Durka W
- Duursma R
- Dymova O
- E-Vojtko A
- Eckstein RL
- Ejtehadi H
- Elser J
- Emilio T
- Engemann K
- Erfanian MB
- Erfmeier A
- Esquivel-Muelbert A
- Esser G
- Estiarte M
- Fagan WF
- Fagundez J
- Falster DS
- Fan Y
- Fang JY
- Farris E
- Fazlioglu F
- Feng YH
- Fernandez-Mendez F
- Ferrara C
- Ferreira J
- Fidelis A
- Finegan B
- Firn J
- Flowers TJ
- Flynn DFB
- Fontana V
- Forey E
- Forgiarini C
- Francois L
- Frangipani M
- Frank D
- Frenette-Dussault C
- Freschet GT
- Fry EL
- Fyllas NM
- Gachet S
- Gallagher R
- Ganade G
- Ganga F
- Garcia-Palacios P
- Gargaglione V
- Garnier E
- Garrido JL
- Garvizu GS
- Gea-Izquierdo G
- Gibson D
- Gillison AN
- Giroldo A
- Glasenhardt MC
- Gleason S
- Gliesch M
- Goldberg E
- Goldel B
- Gonzalez-Akre E
- Gonzalez-Andujar JL
- Gonzalez-Melo A
- Gonzalez-Robles A
- Graae BJ
- Granda E
- Graves S
- Green WA
- Gregor T
- Gross N
- Guerin GR
- Gunther A
- Gutierrez AG
- Haddock L
- Haines A
- Hall J
- Hambuckers A
- Han WX
- Harrison SP
- Hattingh W
- Hawes JE
- He PC
- He TH
- Heberling JM
- Helm A
- Hempel S
- Hentschel J
- Herault B
- Heres AM
- Herz K
- Heuertz M
- Hickler T
- Hietz P
- Higuchi P
- Hipp AL
- Hirons A
- Hock M
- Hogan JA
- Holl K
- Honnay O
- Hornstein D
- Hou EQ
- Hough-Snee N
- Hovstad KA
- Ichie T
- Igic B
- Illa E
- Isaac M
- Ishihara M
- Ivanov L
- Ivanova L
- Iversen CM
- Izquierdo J
- Jackson B
- Jackson RB
- Jactel H
- Jagodzinski AM
- Jandt U
- Jansen S
- Jenkins T
- Jentsch A
- Jespersen JRP
- Jiang GF
- Johansen JL
- Johnson D
- Jokela EJ
- Joly CA
- Jordan GJ
- Joseph GS
- Junaedi D
- Junker RR
- Justes E
- Kabzems R
- Kane J
- Kaplan Z
- Kattenborn T
- Kattge J
- Kavelenova L
- Kearsley E
- Kempel A
- Kenzo T
- Kerkhoff A
- Khalil MI
- Kinlock NL
- Kissling WD
- Kitajima K
- Kitzberger T
- Kjoller R
- Klein T
- Kleyer M
- Klimesova J
- Klipel J
- Kloeppel B
- Klotz S
- Knops JMH
- Kohyama T
- Koike F
- Kollmann J
- Komac B
- Komatsu K
- Konig C
- Kraft NJB
- Kramer K
- Kreft H
- Kuhn I
- Kumarathunge D
- Kuppler J
- Kurokawa H
- Kurosawa Y
- Kuyah S
- Laclau JP
- Lafleur B
- Lallai E
- Lamb E
- Lamprecht A
- Larkin DJ
- Laughlin D
- Lavorel S
- Le Bagousse-Pinguet Y
- le Maire G
- le Roux E
- le Roux PC
- Leadley P
- Lee T
- Lens F
- Lewis SL
- Lhotsky B
- Li XE
- Li YZ
- Lichstein JW
- Liebergesell M
- Lim JY
- Lin YS
- Linares JC
- Liu CJ
- Liu DJ
- Liu U
- Livingstone S
- Llusia J
- Lohbeck M
- Lopez-Garcia A
- Lopez-Gonzalez G
- Lososova Z
- Louault F
- Lukacs BA
- Lukes P
- Luo YJ
- Lussu M
- Ma SY
- Mack M
- Maire V
- Makela A
- Makinen H
- Malhado ACM
- Mallik A
- Manning P
- Manzoni S
- Marchetti Z
- Marchino L
- Marcilio-Silva V
- Marcon E
- Marignani M
- Markesteijn L
- Marques M
- Martin A
- Martinez-Garza C
- Martinez-Vilalta J
- Maskova T
- Mason K
- Mason N
- Massad TJ
- Masse J
- Mayrose I
- Mazzochini GG
- McCarthy J
- McCormack ML
- McCulloh K
- McFadden IR
- McGill BJ
- McPartland MY
- Medeiros JS
- Medlyn B
- Meerts P
- Mehrabi Z
- Meir P
- Melo FPL
- Mencuccini M
- Meredieu C
- Messier J
- Meszaros I
- Metsaranta J
- Michaletz ST
- Michelaki C
- Migalina S
- Milla R
- Miller JED
- Minden V
- Ming R
- Mokany K
- Moles AT
- Molnar VA
- Molofsky J
- Molz M
- Montgomery RA
- Monty A
- Moravcova L
- Moreno-Martinez A
- Moretti M
- Mori AS
- Mori S
- Morris D
- Morrison J
- Mucina L
- Mueller S
- Muir CD
- Muller SC
- Munoz F
- Myers-Smith IH
- Myster RW
- Nagano M
- Naidu S
- Narayanan A
- Natesan B
- Negoita L
- Nelson AS
- Neuschulz EL
- Ni J
- Niedrist G
- Nieto J
- Niinemets U
- Nolan R
- Nottebrock H
- Nouvellon Y
- Novakovskiy A
- Nystuen KO
- O'Grady A
- O'Hara K
- O'Reilly-Nugent A
- Oakley S
- Oberhuber W
- Ohtsuka T
- Oliveira R
- Ollerer K
- Olson ME
- Onipchenko V
- Onoda Y
- Onstein RE
- Ordonez JC
- Osada N
- Ostonen I
- Ottaviani G
- Otto S
- Overbeck GE
- Ozinga WA
- Pahl AT
- Paine CET
- Pakeman RJ
- Papageorgiou AC
- Parfionova E
- Partel M
- Patacca M
- Paula S
- Paule J
- Pauli H
- Pausas JG
- Peco B
- Penuelas J
- Perea A
- Pereira CMR
- Peri PL
- Petisco-Souza AC
- Petraglia A
- Petritan AM
- Phillips OL
- Pierce S
- Pillar VD
- Pinho BX
- Pisek J
- Pomogaybin A
- Poorter H
- Portsmuth A
- Poschlod P
- Potvin C
- Pounds D
- Powell AS
- Power SA
- Prentice IC
- Prinzing A
- Puglielli G
- Pysek P
- Raevel V
- Rammig A
- Ransijn J
- Ray CA
- Reich PB
- Reichstein M
- Reid DEB
- Rejou-Mechain M
- Ribeiro S
- Richardson S
- Riibak K
- Rillig MC
- Riviera F
- Robert EMR
- Roberts S
- Robroek B
- Roddy A
- Rodrigues AV
- Rogers A
- Rollinson E
- Rolo V
- Romermann C
- Ronzhina D
- Roscher C
- Rosell JA
- Rosenfield MF
- Rossi C
- Roy DB
- Royer-Tardif S
- Ruger N
- Ruiz-Peinado R
- Rumpf SB
- Rusch GM
- Ryo M
- Sack L
- Saldana A
- Salgado-Negret B
- Salguero-Gomez R
- Santa-Regina I
- Santacruz-Garcia AC
- Santos J
- Sardans J
- Scalon MC
- Schamp B
- Scherer-Lorenzen M
- Schleuning M
- Schmid B
- Schmidt M
- Schmitt S
- Schneider JV
- Schowanek SD
- Schrader J
- Schrodt F
- Schuldt B
- Schurr F
- Semchenko M
- Seymour C
- Sfair JC
- Sharpe JM
- Sheppard CS
- Sheremetiev S
- Shiodera S
- Shipley B
- Shovon TA
- Siebenkas A
- Sierra C
- Silva M
- Silva V
- Sitzia T
- Sjoman H
- Slot M
- Smith NG
- Sodhi D
- Soltis D
- Soltis P
- Somers B
- Sonnier G
- Sorensen MV
- Sosinski EE
- Soudzilovskaia NA
- Souza AF
- Spasojevic M
- Sperandii MG
- Stan AB
- Stegen J
- Steinbauer K
- Stephan JG
- Sterck F
- Stojanovic DB
- Strydom T
- Suarez ML
- Svenning JC
- Svitkova I
- Svitok M
- Svoboda M
- Swaine E
- Swenson N
- Tabarelli M
- Takagi K
- Tappeiner U
- Tarifa R
- Tarin T
- Tautenhahn S
- Tauugourdeau S
- Tavsanoglu C
- te Beest M
- Tedersoo L
- Thiffault N
- Thom D
- Thomas E
- Thompson K
- Thornton PE
- Thuiller W
- Tichy L
- Tissue D
- Tjoelker MG
- Tng DYP
- Tobias J
- Torok P
- Torres-Ruiz JM
- Tothmeresz B
- Treurnicht M
- Trivellone V
- Trolliet F
- Trotsiuk V
- Tsakalos JL
- Tsiripidis I
- Tysklind N
- Umehara T
- Usoltsev V. A.
- Vadeboncoeur M
- Vaezi J
- Valderrama MY
- Valladares F
- Vamosi J
- van Bodegom PM
- van Breugel M
- Van Cleemput E
- van de Weg M
- van der Merwe S
- van der Plas F
- van der Sande MT
- van Kleunen M
- Van Meerbeek K
- Vanderwel M
- Vanselow KA
- Varhammar A
- Varone L
- Vassilev K
- Vellend M
- Veneklaas EJ
- Verbeeck H
- Verheyen K
- Vibrans A
- Vieira I
- Villacis J
- Violle C
- Vivek P
- Wagner K
- Waldram M
- Waldron A
- Walker AP
- Waller M
- Walther G
- Wang F
- Wang H
- Wang WQ
- Watkins H
- Watkins J
- Weber U
- Weedon JT
- Wei LP
- Weigelt P
- Weiher E
- Wells AW
- Wellstein C
- Wenk E
- Werner GDA
- Westoby M
- Westwood A
- White PJ
- Whitten M
- Williams M
- Winkler DE
- Winter K
- Wirth C
- Womack C
- Wright IJ
- Wright J
- Wright SJ
- Ximenes F
- Yamada T
- Yamaji K
- Yanai R
- Yankov N
- Yguel B
- Zanini KJ
- Zanne AE
- Zeleny D
- Zhao YP
- Zheng J
- Zheng JM
- Zieminska K
- Zirbel CR
- Zizka G
- Zo-Bi IC
- Zotz G
- Publication venue
- 'Royal College of Obstetricians & Gynaecologists (RCOG)'
- Publication date
- 01/01/2020
- Field of study
Plant traits-the morphological, anatomical, physiological, biochemical and phenological characteristics of plants-determine how plants respond to environmental factors, affect other trophic levels, and influence ecosystem properties and their benefits and detriments to people. Plant trait data thus represent the basis for a vast area of research spanning from evolutionary biology, community and functional ecology, to biodiversity conservation, ecosystem and landscape management, restoration, biogeography and earth system modelling. Since its foundation in 2007, the TRY database of plant traits has grown continuously. It now provides unprecedented data coverage under an open access data policy and is the main plant trait database used by the research community worldwide. Increasingly, the TRY database also supports new frontiers of trait-based plant research, including the identification of data gaps and the subsequent mobilization or measurement of new data. To support this development, in this article we evaluate the extent of the trait data compiled in TRY and analyse emerging patterns of data coverage and representativeness. Best species coverage is achieved for categorical traits-almost complete coverage for 'plant growth form'. However, most traits relevant for ecology and vegetation modelling are characterized by continuous intraspecific variation and trait-environmental relationships. These traits have to be measured on individual plants in their respective environment. Despite unprecedented data coverage, we observe a humbling lack of completeness and representativeness of these continuous traits in many aspects. We, therefore, conclude that reducing data gaps and biases in the TRY database remains a key challenge and requires a coordinated approach to data mobilization and trait measurements. This can only be achieved in collaboration with other initiatives
Measurement of the cross-section of high transverse momentum vector bosons reconstructed as single jets and studies of jet substructure in pp collisions at √s = 7 TeV with the ATLAS detector
- Author
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- Zurzolo G
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- Publication venue
- 'IOP Publishing'
- Publication date
- 01/01/2014
- Field of study
This paper presents a measurement of the cross-section for high transverse momentum W and Z bosons produced in pp collisions and decaying to all-hadronic final states. The data used in the analysis were recorded by the ATLAS detector at the CERN Large Hadron Collider at a centre-of-mass energy of √s = 7 TeV;{\rm Te}{\rm V}andcorrespondtoanintegratedluminosityof4.6\;{\rm f}{{{\rm b}}^{-1}}.ThemeasurementisperformedbyreconstructingtheboostedWorZbosonsinsinglejets.ThereconstructedjetmassisusedtoidentifytheWandZbosons,andajetsubstructuremethodbasedonenergyclusterinformationinthejetcentre−of−massframeisusedtosuppressthelargemulti−jetbackground.Thecross−sectionforeventswithahadronicallydecayingWorZboson,withtransversemomentum{{p}_{{\rm T}}}\gt 320\;{\rm Ge}{\rm V}andpseudorapidity|\eta |\lt 1.9,ismeasuredtobe{{\sigma }_{W+Z}}=8.5\pm 1.7$ pb and is compared to next-to-leading-order calculations. The selected events are further used to study jet grooming techniques
Search for direct pair production of the top squark in all-hadronic final states in proton-proton collisions at s√=8 TeV with the ATLAS detector
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- Zenin O
- Zenis T
- Zerwas D
- Zhang D
- Zhang F
- Zhang H
- Zhang J
- Zhang L
- Zhang X
- Zhang Z
- Zhao Z
- Zhemchugov A
- Zhong J
- Zhou B
- Zhou L
- Zhou N
- Zhu CG
- Zhu H
- Zhu J
- Zhu Y
- Zhuang X
- Zhukov K
- Zibell A
- Zieminska D
- Zimine NI
- Zimmermann C
- Zimmermann R
- Zimmermann S
- Zimmermann S
- Zinonos Z
- Ziolkowski M
- Zobernig G
- Zoccoli A
- zur Nedden M
- Zurzolo G
- Zutshi V
- Zwalinski L
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2014
- Field of study
The results of a search for direct pair production of the scalar partner to the top quark using an integrated luminosity of 20.1fb−1 of proton–proton collision data at √s = 8 TeV recorded with the ATLAS detector at the LHC are reported. The top squark is assumed to decay via t˜→tχ˜01 or t˜→ bχ˜±1 →bW(∗)χ˜01 , where χ˜01 (χ˜±1 ) denotes the lightest neutralino (chargino) in supersymmetric models. The search targets a fully-hadronic final state in events with four or more jets and large missing transverse momentum. No significant excess over the Standard Model background prediction is observed, and exclusion limits are reported in terms of the top squark and neutralino masses and as a function of the branching fraction of t˜ → tχ˜01 . For a branching fraction of 100%, top squark masses in the range 270–645 GeV are excluded for χ˜01 masses below 30 GeV. For a branching fraction of 50% to either t˜ → tχ˜01 or t˜ → bχ˜±1 , and assuming the χ˜±1 mass to be twice the χ˜01 mass, top squark masses in the range 250–550 GeV are excluded for χ˜01 masses below 60 GeV
Search for pair-produced long-lived neutral particles decaying to jets in the ATLAS hadronic calorimeter in ppcollisions at √s=8TeV
- Author
- Aad G
- Abbott B
- Abdallah J
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- Aben R
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- Thompson PD
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- Youssef S
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- Yusuff I
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- Zaidan R
- Zaitsev AM
- Zaman A
- Zambito S
- Zanello L
- Zanzi D
- Zeitnitz C
- Zeman M
- Zemla A
- Zengel K
- Zenin O
- Zenis T
- Zerwas D
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- Zhemchugov A
- Zhong J
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- Zibell A
- Zieminska D
- Zimine NI
- Zimmermann C
- Zimmermann R
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- Zinonos Z
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- Zutshi V
- Zwalinski L
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/01/2014
- Field of study
The ATLAS detector at the Large Hadron Collider at CERN is used to search for the decay of a scalar boson to a pair of long-lived particles, neutral under the Standard Model gauge group, in 20.3fb−1of data collected in proton–proton collisions at √s=8TeV. This search is sensitive to long-lived particles that decay to Standard Model particles producing jets at the outer edge of the ATLAS electromagnetic calorimeter or inside the hadronic calorimeter. No significant excess of events is observed. Limits are reported on the product of the scalar boson production cross section times branching ratio into long-lived neutral particles as a function of the proper lifetime of the particles. Limits are reported for boson masses from 100 GeVto 900 GeV, and a long-lived neutral particle mass from 10 GeVto 150 GeV
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