13 research outputs found

    Outcomes from elective colorectal cancer surgery during the SARS-CoV-2 pandemic

    Get PDF
    This study aimed to describe the change in surgical practice and the impact of SARS-CoV-2 on mortality after surgical resection of colorectal cancer during the initial phases of the SARS-CoV-2 pandemic

    Nurses' perceptions of aids and obstacles to the provision of optimal end of life care in ICU

    Get PDF
    Contains fulltext : 172380.pdf (publisher's version ) (Open Access

    Tumor maligno da bainha dos nervos periféricos do pulmão: A propósito de um caso clínico

    Get PDF
    Resumo: Os tumores malignos da bainha dos nervos perifĂ©ricos correspondem a um grupo raro de sarcomas de tecidos moles que tendem a ocorrer em doentes com neurofibromatose tipo 1 ou vĂĄrios anos apĂłs tratamentos de radioterapia. A sua localização torĂĄcica Ă© uma entidade muito rara. A sintomatologia habitual deve-se ao efeito de massa exercido sobre os nervos, podendo persistir durante meses ou anos antes do diagnĂłstico. A escassez de doentes com este tipo de tumor faz com que a abordagem terapĂȘutica ainda permaneça em debate, sendo a cirurgia o procedimento de eleição. O prognĂłstico destes doentes Ă© mau dada a grande recorrĂȘncia local e metastização. O caso clĂ­nico descrito serve de tema Ă  discussĂŁo. Abstract: Malignant peripheral nerve sheath tumors comprehend a rare group of soft tissue sarcomas that tend to occur in patients with neurofibromatosis type 1 or several years after radiotherapy treatments. Its thoracic localization is a very unusual entity. The typical symptoms are due to nerve roots compression which can persist for several months or years before diagnosis. Due to very few patients with this type of tumor its therapeutic approach is still a matter of permanent debate, being surgery the main treatment. This tumor has a bad prognosis because of high local recurrence and metastasis. The clinical case we describe serves as a glimpse for discussion. Palavras-chave: Tumor maligno, bainha nervo perifĂ©rico, Key-words: Malignant tumour, peripheral nerve sheat

    Tumor maligno da bainha dos nervos periféricos do pulmão: A propósito de um caso clínico Malignant peripheral nerve sheath tumors: A case report

    No full text
    Os tumores malignos da bainha dos nervos perifĂ©ricos correspondem a um grupo raro de sarcomas de tecidos moles que tendem a ocorrer em doentes com neurofibromatose tipo 1 ou vĂĄrios anos apĂłs tratamentos de radioterapia. A sua localização torĂĄcica Ă© uma entidade muito rara. A sintomatologia habitual deve-se ao efeito de massa exercido sobre os nervos, podendo persistir durante meses ou anos antes do diagnĂłstico. A escassez de doentes com este tipo de tumor faz com que a abordagem terapĂȘutica ainda permaneça em debate, sendo a cirurgia o procedimento de eleição. O prognĂłstico destes doentes Ă© mau dada a grande recorrĂȘncia local e metastização. O caso clĂ­nico descrito serve de tema Ă  discussĂŁo.Malignant peripheral nerve sheath tumors comprehend a rare group of soft tissue sarcomas that tend to occur in patients with neurofibromatosis type 1 or several years after radiotherapy treatments. Its thoracic localization is a very unusual entity. The typical symptoms are due to nerve roots compression which can persist for several months or years before diagnosis. Due to very few patients with this type of tumor its therapeutic approach is still a matter of permanent debate, being surgery the main treatment. This tumor has a bad prognosis because of high local recurrence and metastasis. The clinical case we describe serves as a glimpse for discussion

    Low nadir CD4+ T-cell counts predict gut dysbiosis in HIV-1 infection

    No full text

    Delaying surgery for patients with a previous SARS-CoV-2 infection

    Get PDF
    Not availabl

    Elective Cancer Surgery in COVID-19–Free Surgical Pathways During the SARS-CoV-2 Pandemic: An International, Multicenter, Comparative Cohort Study

    No full text

    The impact of surgical delay on resectability of colorectal cancer: An international prospective cohort study

    Get PDF
    AimThe SARS-CoV-2 pandemic has provided a unique opportunity to explore the impact of surgical delays on cancer resectability. This study aimed to compare resectability for colorectal cancer patients undergoing delayed versus non-delayed surgery.MethodsThis was an international prospective cohort study of consecutive colorectal cancer patients with a decision for curative surgery (January-April 2020). Surgical delay was defined as an operation taking place more than 4 weeks after treatment decision, in a patient who did not receive neoadjuvant therapy. A subgroup analysis explored the effects of delay in elective patients only. The impact of longer delays was explored in a sensitivity analysis. The primary outcome was complete resection, defined as curative resection with an R0 margin.ResultsOverall, 5453 patients from 304 hospitals in 47 countries were included, of whom 6.6% (358/5453) did not receive their planned operation. Of the 4304 operated patients without neoadjuvant therapy, 40.5% (1744/4304) were delayed beyond 4 weeks. Delayed patients were more likely to be older, men, more comorbid, have higher body mass index and have rectal cancer and early stage disease. Delayed patients had higher unadjusted rates of complete resection (93.7% vs. 91.9%, P = 0.032) and lower rates of emergency surgery (4.5% vs. 22.5%, P ConclusionOne in 15 colorectal cancer patients did not receive their planned operation during the first wave of COVID-19. Surgical delay did not appear to compromise resectability, raising the hypothesis that any reduction in long-term survival attributable to delays is likely to be due to micro-metastatic disease
    corecore