Combined Human, Antenna Orientation in Elevation Direction and Ground Effect on RSSI in Wireless Sensor Networks

In this paper, we experimentally investigate the combined effect of human, antenna orientation in elevation direction and the ground effect on the Received Signal Strength Indicator (RSSI) parameter in the Wireless Sensor Network (WSN). In experiment, we use MICAz motes and consider different scenarios where antenna of the transmitter node is tilted in elevation direction. The motes were placed on the ground to take into account the ground effect on the RSSI. The effect of one, two and four persons on the RSSI is recorded. For one and two persons, different walking paces e.g. slow, medium and fast pace, are analysed. However, in case of four persons, random movement is carried out between the pair of motes. The experimental results show that some antenna orientation angles have drastic effect on the RSSI, even without any human activity. The fluctuation count and range of RSSI in different scenarios with same walking pace are completely different. Therefore, an efficient human activity algorithm is need that effectively takes into count the antenna elevation and other parameters to accurately detect the human activity in the WSN deployment region.Comment: 10th IEEE International Conference on Frontiers of Information Technology (FIT 12), 201

Opioids Delay Healing of Spinal Fusion: A Rabbit Posterolateral Lumbar Fusion Model

Background Context Opioid use is prevalent in the management of pre- and postoperative pain in patients undergoing spinal fusion. There is evidence that opioids downregulate osteoblasts in vitro, and a previous study found that morphine delays the maturation and remodeling of callus in a rat femur fracture model. However, the effect of opioids on healing of spinal fusion has not been investigated before. Isolating the effect of opioid exposure in humans would be limited by the numerous confounding factors that affect fusion healing. Therefore, we have used a well-established rabbit model to study the process of spinal fusion healing that closely mimics humans. Purpose The objective of this work was to study the effect of systemic opioids on the process of healing of spinal fusion in a rabbit posterolateral spinal fusion model. Study Design/Setting This is a preclinical animal study. Materials and Methods Twenty-four adult New Zealand white rabbits were studied in two groups after approval from the Institutional Animal Care and Use Committee (IACUC). The opioid group (n=12) received 4 weeks\u27 preoperative and 6 weeks\u27 postoperative transdermal fentanyl. Serum fentanyl levels were measured just before surgery and 4 weeks postoperatively to ensure adequate levels. The control group (n=12) received only perioperative pain control as necessary. All animals underwent a bilateral L5–L6 posterolateral spinal fusion using iliac crest autograft. Animals were euthanized at the 6-week postoperative time point, and assessment of fusion was done by manual palpation, plain radiographs, microcomputed tomography (microCT), and histology. Results Twelve animals in the control group and 11 animals in the opioid group were available for analysis at the end of 6 weeks. The fusion scores on manual palpation, radiographs, and microCT were not statistically different. Three-dimensional microCT morphometry found that the fusion mass in the opioid group had a lower bone volume (p=.09), a lower trabecular number (p=.02), and a higher trabecular separation (p=.02) compared with the control group. Histologic analysis found areas of incorporation of autograft and unincorporated graft fragments in both groups. In the control group, there was remodeling of de novo woven bone to lamellar organization with incorporation of osteocytes, formation of mature marrow, and relative paucity of hypertrophied osteoblasts lining new bone. Sections from the opioid group showed formation of de novo woven bone, and hypertrophied osteoblasts were seen lining the new bone. There were no sections showing lamellar organization and development of mature marrow elements in the opioid group. Less dense trabeculae on microCT correlated with histologic findings of relatively immature fusion mass in the opioid group. Conclusions Systemic opioids led to an inferior quality fusion mass with delay in maturation and remodeling at 6 weeks in this rabbit spinal fusion model. These preliminary results lay the foundation for further research to investigate underlying cellular mechanisms, the temporal fusion process, and the dose-duration relationship of opioids responsible for our findings

Efficiency enhancement strategy implementation in hybrid electric vehicles using sliding mode control

Introduction. Hybrid electric vehicles are offering the most economically viable choices in today's automotive industry, providing best solutions for a very high fuel economy and low rate of emissions. The rapid progress and development of this industry has prompted progress of human beings from primitive level to a very high industrial society where mobility used to be a fundamental need. However, the use of large number of automobiles is causing serious damage to our environment and human life. At present most of the vehicles are relying on burning of hydrocarbons in order to achieve power of propulsion to drive wheels. Therefore, there is a need to employ clean and efficient vehicles like hybrid electric vehicles. Unfortunately, earlier control strategies of series hybrid electric vehicle fail to include load disturbances during the vehicle operation and some of the variations of the nonlinear parameters (e.g. stator’s leakage inductance, resistance of winding etc.). The novelty of the proposed work is based on designing and implementing two robust sliding mode controllers (SMCs) on series hybrid electric vehicle to improve efficiency in terms of both speed and torque respectively. The basic idea is to let the engine operate only when necessary keeping in view the state of charge of battery. Purpose. In proposed scheme, both performance of engine and generator is being controlled, one sliding mode controllers is controlling engine speed and the other one is controlling generator torque, and results are then compared using 1-SMC and 2-SMC’s. Method. The series hybrid electric vehicle powertrain considered in this work consists of a battery bank and an engine-generator set which is referred to as the auxiliary power unit, traction motor, and power electronic circuits to drive the generator and traction motor. The general strategy is based on the operation of the engine in its optimal efficiency region by considering the battery state of charge. Results .Mathematical models of engine and generator were taken into consideration in order to design sliding mode controllers both for engine speed and generator torque control. Vehicle was being tested on standard cycle. Results proved that, instead of using only one controller for engine speed, much better results are achieved by simultaneously using two sliding mode controllers, one controlling engine speed and other controlling generator torque.Вступ. Гібридні електромобілі пропонують найбільш економічно доцільний вибір у сучасній автомобільній промисловості, надаючи найкращі рішення для дуже високої економії палива та низького рівня викидів. Швидкий прогрес та розвиток цієї галузі підштовхнули людей до переходу від примітивного рівня до дуже високого індустріального суспільства, де мобільність була фундаментальною потребою. Однак використання великої кількості автомобілів завдає серйозної шкоди довкіллю та життю людини. Нині більшість транспортних засобів покладаються на спалювання вуглеводнів задля досягнення потужності руху на провідних колесах. Отже, необхідно використовувати чисті та ефективні транспортні засоби, такі як гібридні електромобілі. На жаль, раніше стратегії управління серійним гібридним електромобілем не враховували збурення навантаження під час роботи автомобіля і деякі зміни нелінійних параметрів (наприклад, індуктивність розсіювання статора, опір обмотки і т.д.). Новизна запропонованої роботи заснована на розробці та реалізації двох надійних контролерів ковзного режиму (SMC) на серійному гібридному електромобілі для підвищення ефективності з точки зору швидкості та моменту, що крутить, відповідно. Основна ідея полягає в тому, щоб дозволити двигуну працювати тільки тоді, коли це необхідно з урахуванням стану заряду акумулятора. Мета. У пропонованій схемі контролюються характеристики як двигуна, так і генератора, один контролер ковзного режиму регулює швидкість двигуна, а інший регулює крутний момент генератора, а потім результати порівнюються з використанням режимів 1-SMC і 2-SMC. Метод. Силова установка серійного гібридного електромобіля, що розглядається в даній роботі, складається з акумуляторної батареї та установки двигун-генератор, яка називається допоміжною силовою установкою, тяговим двигуном та силовими електронними схемами для приводу генератора та тягового двигуна. Загальна стратегія заснована на роботі двигуна в області оптимальної ефективності з урахуванням рівня заряду акумуляторної батареї. Результати. Математичні моделі двигуна та генератора були прийняті до уваги для розробки регуляторів ковзного режиму як для керування частотою обертання двигуна, так і для керування крутним моментом генератора. Транспортний засіб випробовувався за стандартним циклом. Результати показали, що замість використання лише одного регулятора частоти обертання двигуна набагато кращі результати досягаються при одночасному використанні двох регуляторів ковзного режиму, один з яких керує частотою обертання двигуна, а інший - моментом, що крутить, генератора

Efficiency enhancement strategy implementation in hybrid electric vehicles using sliding mode control

Introduction. Hybrid electric vehicles are offering the most economically viable choices in today's automotive industry, providing best solutions for a very high fuel economy and low rate of emissions. The rapid progress and development of this industry has prompted progress of human beings from primitive level to a very high industrial society where mobility used to be a fundamental need. However, the use of large number of automobiles is causing serious damage to our environment and human life. At present most of the vehicles are relying on burning of hydrocarbons in order to achieve power of propulsion to drive wheels. Therefore, there is a need to employ clean and efficient vehicles like hybrid electric vehicles. Unfortunately, earlier control strategies of series hybrid electric vehicle fail to include load disturbances during the vehicle operation and some of the variations of the nonlinear parameters (e.g. stator’s leakage inductance, resistance of winding etc.). The novelty of the proposed work is based on designing and implementing two robust sliding mode controllers (SMCs) on series hybrid electric vehicle to improve efficiency in terms of both speed and torque respectively. The basic idea is to let the engine operate only when necessary keeping in view the state of charge of battery. Purpose. In proposed scheme, both performance of engine and generator is being controlled, one sliding mode controllers is controlling engine speed and the other one is controlling generator torque, and results are then compared using 1-SMC and 2-SMC’s. Method. The series hybrid electric vehicle powertrain considered in this work consists of a battery bank and an engine-generator set which is referred to as the auxiliary power unit, traction motor, and power electronic circuits to drive the generator and traction motor. The general strategy is based on the operation of the engine in its optimal efficiency region by considering the battery state of charge. Results .Mathematical models of engine and generator were taken into consideration in order to design sliding mode controllers both for engine speed and generator torque control. Vehicle was being tested on standard cycle. Results proved that, instead of using only one controller for engine speed, much better results are achieved by simultaneously using two sliding mode controllers, one controlling engine speed and other controlling generator torque.Вступ. Гібридні електромобілі пропонують найбільш економічно доцільний вибір у сучасній автомобільній промисловості, надаючи найкращі рішення для дуже високої економії палива та низького рівня викидів. Швидкий прогрес та розвиток цієї галузі підштовхнули людей до переходу від примітивного рівня до дуже високого індустріального суспільства, де мобільність була фундаментальною потребою. Однак використання великої кількості автомобілів завдає серйозної шкоди довкіллю та життю людини. Нині більшість транспортних засобів покладаються на спалювання вуглеводнів задля досягнення потужності руху на провідних колесах. Отже, необхідно використовувати чисті та ефективні транспортні засоби, такі як гібридні електромобілі. На жаль, раніше стратегії управління серійним гібридним електромобілем не враховували збурення навантаження під час роботи автомобіля і деякі зміни нелінійних параметрів (наприклад, індуктивність розсіювання статора, опір обмотки і т.д.). Новизна запропонованої роботи заснована на розробці та реалізації двох надійних контролерів ковзного режиму (SMC) на серійному гібридному електромобілі для підвищення ефективності з точки зору швидкості та моменту, що крутить, відповідно. Основна ідея полягає в тому, щоб дозволити двигуну працювати тільки тоді, коли це необхідно з урахуванням стану заряду акумулятора. Мета. У пропонованій схемі контролюються характеристики як двигуна, так і генератора, один контролер ковзного режиму регулює швидкість двигуна, а інший регулює крутний момент генератора, а потім результати порівнюються з використанням режимів 1-SMC і 2-SMC. Метод. Силова установка серійного гібридного електромобіля, що розглядається в даній роботі, складається з акумуляторної батареї та установки двигун-генератор, яка називається допоміжною силовою установкою, тяговим двигуном та силовими електронними схемами для приводу генератора та тягового двигуна. Загальна стратегія заснована на роботі двигуна в області оптимальної ефективності з урахуванням рівня заряду акумуляторної батареї. Результати. Математичні моделі двигуна та генератора були прийняті до уваги для розробки регуляторів ковзного режиму як для керування частотою обертання двигуна, так і для керування крутним моментом генератора. Транспортний засіб випробовувався за стандартним циклом. Результати показали, що замість використання лише одного регулятора частоти обертання двигуна набагато кращі результати досягаються при одночасному використанні двох регуляторів ковзного режиму, один з яких керує частотою обертання двигуна, а інший - моментом, що крутить, генератора

Dynamically sampled multivariate empirical mode decomposition

A method for accurate multivariate local mean estimation in the multivariate empirical mode decomposition algorithm by using a statistical data-driven approach based on the Menger curvature measure and normal-to-anything variate-generation method is proposed. This is achieved by aligning the projection vectors in the direction of the maximum `activity' of the input signal by considering the local curvature of the signal in multidimensional spaces, resulting in accurate mean estimation even for a very small number of projection vectors

EFFECT OF INDUCED MUTATION FOR VARIETAL IMPROVEMENT IN SOME LOCAL GRAPEVINE CULTIVARS

ABSTRACT Grape is important crop with high nutritional value, however there is a great need for improving the quality of the crop. Cultures were maintained in vitro on MS medium supplemented with 2.5 mg/L BAP+ TDZ 3.0 mg/ L. The effect of different doses of gamma irradiation as well as chemical mutagenesis by Sodium azide was studied. It was noted that doses up to 5 Gy helped to increase plant height from irradiated nodes. At 5 Gy, there was an increase of 4.7, 5 and 4.5 cm in plant height in Desi, Sundar Khani and Chinese varieties of grapes respectively. On further increase in concentration from 6 to 10 Gy, there was a gradual decrease in plant height. Sodium azide was selected to induce mutations in the nodal explants. Nodal explants of the varieties were subjected to different sodium azide concentrations ranging from 0.1 to 0.5%. It was noted that the height of plantlet decreased with an increase in concentration of sodium azide In explants treated with 0.2% sodium azide the plant height was 4 cm which increased to 4.2cm when the explants were treated with 0.3% sodium azide. Further increase in concentration not only caused decreases in length but also led to complete necrosis. In the present study, DNA analysis by RAPD markers was used to analyze mutagenesis. The RAPD analyses indicated that the plantlets subjected to gamma radiation had a great genetic diversity as compared to the control

Extraction and quantification of polyphenols from kinnow (Citrus reticulate L.) peel using ultrasound and maceration techniques

AbstractAn investigation was carried out to extract polyphenols from the peel of kinnow (Citrus reticulate L.) by maceration and ultrasound-assisted extraction (UAE) techniques. The antioxidant potential of these polyphenols was evaluated using ferric reducing antioxidant power (FRAP), 2,2-diphenyl-1-picrylhydrazyl (DPPH), and superoxide radical scavenging assays; and their antimicrobial activity was assessed against bacterial strains Staphyloccoccus aureus, Bacillus cereus, and Salmonella typhimurium. The highest extraction yield was obtained through the solvent ethanol at 80% concentration level, whereas UAE was a more efficient technique and yielded comparatively higher polyphenol contents than maceration. Maximum polyphenols were extracted with 80% methanol [32.48 mg gallic acid equivalent (GAE)/g extract] using UAE, whereas minimum phenolics (8.64 mg GAE/g extract) were obtained with 80% ethyl acetate through the maceration technique. Elevated antioxidant activity of kinnow peel extracts was exhibited in three antioxidant assays, where 80% methanolic extracts showed the highest antioxidant activity (27.67±1.11mM/100 g for FRAP) and the highest scavenging activity, 72.83±0.65% and 64.80±0.91% for DPPH and superoxide anion radical assays, respectively. Strong correlations between total polyphenols and antioxidant activity were recorded. Eleven phenolic compounds—including five phenolic acids and six flavonoids—were identified and quantified by high performance liquid chromatography. Ferulic acid and hesperidin were the most abundant compounds whereas caffeic acid was the least abundant phenolic compound in kinnow peel extracts. Maximum inhibition zone was recorded against S. aureus (16.00±0.58 mm) whereas minimum inhibition zone was noted against S. typhimurium (9.00±1.16 mm). It was concluded that kinnow mandarin peels, being a potential source of phenolic compounds with antioxidant and antimicrobial properties, may be used as an ingredient for the preparation of functional foods

Tobacco and cigarette butt consumption in humans and animals

Discarded cigarette butts may present health risks to human infants and animals because of indiscriminate eating behaviours. Nicotine found in cigarette butts may cause vomiting and neurological toxicity; leachates of cigarette butts in aquatic environments may cause exposure to additional toxic chemicals including heavy metals, ethyl phenol and pesticide residues. This report reviews published and grey literature regarding cigarette butt waste consumption by children, pets and wildlife. Although reports of human and animal exposures number in the tens of thousands, severe toxic outcomes due to butt consumption are rare. Nonetheless, the ubiquity of cigarette butt waste and its potential for adverse effects on human and animal health warrants additional research and policy interventions to reduce the stream of these pollutants in the environment

Mathematical assessment of the role of waning and boosting immunity against the BA.1 Omicron variant in the United States

The Simons Foundation, the National Science Foundation and the Fulbright Foreign Student Program.Three safe and effective vaccines against SARS-CoV-2 have played a major role in combating COVID-19 in the United States. However, the effectiveness of these vaccines and vaccination programs has been challenged by the emergence of new SARS-CoV-2 variants of concern. A new mathematical model is formulated to assess the impact of waning and boosting of immunity against the Omicron variant in the United States. To account for gradual waning of vaccine-derived immunity, we considered three vaccination classes that represent high, moderate and low levels of immunity. We showed that the disease-free equilibrium of the model is globally-asymptotically, for two special cases, if the associated reproduction number is less than unity. Simulations of the model showed that vaccinederived herd immunity can be achieved in the United States via a vaccination-boosting strategy which entails fully vaccinating at least 59% of the susceptible populace followed by the boosting of about 72% of the fully-vaccinated individuals whose vaccine-derived immunity has waned to moderate or low level. In the absence of boosting, waning of immunity only causes a marginal increase in the average number of new cases at the peak of the pandemic, while boosting at baseline could result in a dramatic reduction in the average number of new daily cases at the peak. Specifically, for the fast immunity waning scenario (where both vaccine-derived and natural immunity are assumed to wane within three months), boosting vaccine-derived immunity at baseline reduces the average number of daily cases at the peak by about 90% (in comparison to the corresponding scenario without boosting of the vaccine-derived immunity), whereas boosting of natural immunity (at baseline) only reduced the corresponding peak daily cases (in comparison to the corresponding scenario without boosting of natural immunity) by approximately 62%. Furthermore, boosting of vaccine-derived immunity is more beneficial (in reducing the burden of the pandemic) than boosting of natural immunity. Finally, boosting vaccine-derived immunity increased the prospects of altering the trajectory of COVID-19 from persistence to possible elimination.http://www.aimspress.com/journal/MBEam2024Mathematics and Applied MathematicsSDG-03:Good heatlh and well-bein

Is a single positive blood culture for Enterococcus species representative of infection or contamination?

Abstract Data on the clinical outcomes of patients with a single compared with multiple positive blood cultures for Enterococcus species is limited. We undertook a retrospective cohort study in adults with at least one positive blood culture for Enterococcus species in a single institution. Clinical outcomes included death and elimination of infection. We included 471 positive blood cultures from 206 enterococcal positive blood culture episodes in 189 patients. Multiple positive blood cultures for Enterococcus species occurred in 110/206 (53.4 %) episodes; 31.6 % of patients had diabetes mellitus; 42.9 % of patients had solid or hematologic malignancy; 26.5 % of patients were solid organ transplant recipients; hospital-acquired and healthcare-associated acquisition represented 55.3 % and 33.0 % of episodes, respectively. Thirtyfive patients died and 110 episodes of enterococcal bloodstream infection were successfully treated. In the multivariable analysis, multiple positive blood cultures were not statistically significantly associated with an increased likelihood of in-hospital death [odds ratio (OR) 1.00, 95 % confidence interval (CI) 0.42-2.40] or elimination (OR 1.41, 95 % CI 0.76-2.64) compared with single positive blood cultures. Hematologic malignancy and diabetes mellitus were independently associated with in-hospital death (OR 2.83, 95 % Cl 1.02-7.82; OR 2.79, 95 % Cl 1.16-6.70, respectively). Infectious disease consultation was associated with a greater likelihood of elimination (OR 2.50, 95 % Cl 1.32-4.72). The clinical outcomes of patients with single versus multiple positive blood cultures with Enterococcus species were similar in our institution. Further studies should examine efficient methods to detect contamination versus true infection